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German Lagunas-Robles

@g-lagunasrobles.bsky.social
168 followers 257 following 22 posts

postdoc @ IU Bloomington (Bracewell Lab) genome evolution., supergenes, sex chromosomes 🐜🧬🪲

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Reposted by German Lagunas-Robles
Neil Tsutsui @neiltsutsui.bsky.social · 08/04/2026
Job alert! Post-doc position available in the Tsutsui lab at UC Berkeley. I'm specifically looking for someone optimize and scale RNA interference for invasive ant control and eradication. Happy to take questions at ntsutsui@berkeley.edu. Spread the word! aprecruit.berkeley.edu/JPF05325
aprecruit.berkeley.edu
Postdoctoral Scholar – Insect Molecular Biology – ESPM (Organisms & the Environment) - Tsutsui Lab
University of California, Berkeley is hiring. Apply now!
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Maria Akopyan, PhD @akopyan.bsky.social · 05/03/2026
Our paper is out in @Science! The Atlantic silverside spans Earth's steepest latitudinal gradient in coastal sea-surface temperature. Despite high gene flow, populations show clinal genetic variation in multiple locally adapted traits. doi.org/10.1126/scie...
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Jonathan Romiguier @selfishmeme.bsky.social · 23/02/2026
Queen-only parasitic parthogenetic ant. Cool combination! www.cell.com/current-biol...
cell.com
A parasitic, parthenogenetic ant with only queens and without workers or males
Hamaguchi, Kinomura and colleagues describe an ant species that lacks workers and males and consists exclusively of queens.
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Molecular Biology and Evolution @molbioevol.bsky.social · 11/02/2026
Thomas et al. reveal that positively selected and differentially expressed hippocampal genes cluster near breakpoints in shrews, tying chromosomal rearrangements and accessible chromatin to adaptation and brain size plasticity. 🔗 doi.org/10.1093/molbev/msag006 📷 Christian Ziegler #evobio #molbio
MBE | Genomic comparisons and the adaptive basis of brain size plasticity and chromosomal instability in the Eurasian common shrew
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German Lagunas-Robles @g-lagunasrobles.bsky.social · 02/02/2026
Check out our paper on the neo-sex chromosomes in mountain pine beetle! We assembled THREE neo-Ys that are quite distinct and their corresponding neo-Xs .
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 09/01/2026
Lethal epistasis maintains strong linkage disequilibrium between unlinked supergenes www.biorxiv.org/content/10.64898/20…
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Hugo Darras @hugodarras.bsky.social · 06/01/2026
New work from @miyapan.bsky.social and our team, bringing ant, bee, and wasp labs together. @chuanxinyu.bsky.social shows that the ANTSR locus we discovered in ants has determined sex for 150+ My across bees and stinging wasps 🐜🐝, despite virtually no sequence conservation 😮 doi.org/10.1073/pnas...
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German Lagunas-Robles @g-lagunasrobles.bsky.social · 26/12/2025
ANTSR seems to be the ancient master sex determining gene in Hymenoptera (as suggested by Pan et al. 2024)! So rad that a lncRNA is doing this! www.biorxiv.org/content/10.6...
biorxiv.org
Evidence for an ancient master sex determination gene in Hymenoptera
The vast majority of Hymenopterans determine sex by haplodiploidy, in which males and females develop from haploid unfertilized and diploid fertilized eggs, respectively. At the molecular level, the m...
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ISYEB @isyeb.mnhn.fr · 21/11/2025
New in @currentbiology.bsky.social "Genomic evidence of a complex supergene system linking dispersal to social polymorphism" #Myrmecina_graminicola Mona,S., Gay,E.J., Ducancel,J., Laso-Jadart,R., Chifflet-Belle, P., Doums,C. @isyeb.mnhn.fr @ephe-psl.bsky.social et al. 🐜 www.cell.com/current-biol...
cell.com
Genomic evidence of a complex supergene system linking dispersal to social polymorphism
Mona et al. report a complex supergene system in the ant Myrmecina graminicola characterized by three alleles determining both the number of queens in a colony (monogyne vs. polygyne) and the presence...
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German Lagunas-Robles @g-lagunasrobles.bsky.social · 18/11/2025
🧬🧬 A human supergene 🧬🧬 www.biorxiv.org/content/10.1...
biorxiv.org
A human supergene: BRCA1, CCDC200, and U2 snRNAs
BRCA1 occurs on one of two major haplotypes in populations of European and Asian ancestry that show signs of selection and functional differences. Near-maximal linkage disequilibrium associated with t...
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PLOS Biology @plosbiology.org · 04/11/2025
#Haplodiploid inheritance is found in all species of #Hymenoptera. @mwbstr.bsky.social &co map the #sex determining #gene of the red mason #bee to the ANTSR gene region, suggesting a shared, ancient origin of #SexDetermination in bees & ants >150 Mya ago @plosbiology.org 🧪 plos.io/47COEtH
Complementary sex determination (CSD) in bees and ants. Top left: Single-locus CSD is likely to be the predominant mode of sex determination in Hymenoptera. CSD loci have been identified in two species: the honeybee Apis mellifera and the invasive ant Linepithema humile. The tree shows evolutionary relationships between these species and Osmia bicornis, the main subject of this study. The origin of Hymenoptera is estimated as 386 million years ago and the common ancestor of Apoidea and Formicoidea is estimated as 153 million years ago. Top right: Under single-locus CSD, females are heterozygous at the CSD locus, whereas males are haploid and therefore hemizygous. A large number of CSD alleles are expected to segregate in outbred populations. A small proportion of homozygotes at the CSD locus are produced by chance, when parents share an allele, which results in the production of sterile diploid males. Middle: An O. bicornis nest consists of a row of cocoons in a tube. The mother lays fertilized diploid eggs deepest in the nest and unfertilized haploid eggs closer to the entrance. Eggs develop into adults inside cocoons. Diploid eggs typically develop into females whereas haploid eggs become male. A small proportion of diploids that are homozygous at the CSD locus develop into diploid males, which occur amongst females and are larger than haploid males. Bottom: A male and female red mason bee mating. Photo by Marie Louise Huskens.
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German Lagunas-Robles @g-lagunasrobles.bsky.social · 17/10/2025
2 year postdoc position in evolutionary genomics at University of California, Riverside in the Purcell Lab! 🧬🐜
2 year postdoc position in evolutionary genomics available at the University of California, Riverside in the Purcell Lab
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Charlotte Wright @charlottewright.bsky.social · 11/09/2025
How many chromosomes can an animal have? In our paper out now in @currentbiology.bsky.social we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact. www.cell.com/current-biol...
tinyurl.com
Constraints on chromosome evolution revealed by the 229 chromosome pairs of the Atlas blue butterfly
The genome of the Atlas blue butterfly contains ten times more chromosomes than most butterflies, and more than any other known diploid animal. Wright et al. show that this extraordinary karyotype is ...
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German Lagunas-Robles @g-lagunasrobles.bsky.social · 11/09/2025
ggplot2 ethusiasts, new update just dropped! 🔥🔥🔥
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Thomas Lin Pedersen @thomasp85.com · 11/09/2025
I am beyond excited to announce that ggplot2 4.0.0 has just landed on CRAN. It's not every day we have a new major #ggplot2 release but it is a fitting 18 year birthday present for the package. Get an overview of the release in this blog post and be on the lookout for more in-depth posts #rstats
tidyverse.org
ggplot2 4.0.0
A new major version of ggplot2 has been released on CRAN. Find out what is new here.
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Nature @nature.com · 03/09/2025
A common type of ant in Europe breaks a fundamental rule in biology: its queens can produce male offspring that are a whole different species go.nature.com/4mOb5T9
go.nature.com
‘Almost unimaginable’: these ants are different species but share a mother
Ant queens of one species clone ants of another to create hybrid workers that do their bidding.
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German Lagunas-Robles @g-lagunasrobles.bsky.social · 02/09/2025
Check out our latest preprint in Formica ants! We investigate how the sex ratio supergene evolved. We find that a colony-level sex ratio supergene evolved twice! This likely occurred as a result of recombination between the the ancestral queen number supergenes present in Formica. 🧬🐜🧬🐜🧬🐜
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German Lagunas-Robles @g-lagunasrobles.bsky.social · 24/07/2025
Excited to share some of the latest work coming from the Formica ant supergene system 🐜🧬! This project represents many collection trips and years of work! doi.org/10.1101/2025...
doi.org
Variation in social organization and supergene control along a latitudinal gradient
Widespread species often experience vastly different environmental conditions across their range. In species with polymorphic traits under strong genetic control, we can investigate how environmental ...
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Judith Mank @judithmank.bsky.social · 27/06/2025
Very pleased to see this officially out - Genome Architecture and Speciation in Plants and Animals. With @siluwang.bsky.social, @dortizba.bsky.social and Loren Rieseberg. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
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Journal of Evolutionary Biology @jevbio.bsky.social · 23/04/2025
The #EditorsChoice for this month from EIC @maxreuter.bsky.social is "Unexpected absence of a multiple-queen supergene haplotype from supercolonial populations of Formica ants" by @g-lagunasrobles.bsky.social et al academic.oup.com/jeb/article/...
academic.oup.com
Unexpected absence of a multiple-queen supergene haplotype from supercolonial populations of Formica ants
Abstract. Ants exhibit many complex social organization strategies. One particularly elaborate strategy is supercoloniality, in which a colony consists of
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German Lagunas-Robles @g-lagunasrobles.bsky.social · 09/04/2025
Is supercoloniality a simple extension of polygyny?Supercolonies, networks of interconnected nests with many queens, have been proposed as a natural extension of multi-queen nests. In many Formica ants, a supergene determines whether a colony has a single queen or many queens. (1/n)
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 26/03/2025
A novel supergene controls queen size and colony social organization in the ant Myrmica ruginodis www.biorxiv.org/content/10.1101/202…
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PLOS Biology @plosbiology.org · 03/03/2025
Dynamics of a supergene. A study of the BC supergene in wing color morphs of the African monarch #butterfly by @rishidekayne.bsky.social &co reveals dynamic evolution of #supergene haplotypes, fueled by incomplete recombination suppression 🧪 @plosbiology.org plos.io/3DiFhnL
Top: Topology weightings across chr15 showing how the karamu haplotype is related to the klugii and orientis haplotypes. Upper panel shows three possible rooted genealogical topologies. Second panel shows weights for each topology along the chromosome, smoothed with a 20 kb span. Arrows above the plot indicate the locations of inversions. Third panel shows unsmoothed topology weightings across a 1.5 Mb region corresponding to Inversion 2. Bottom: Ancestry painting across a 100 kb region within Inversion 2, showing ancestry tracts for two homozygous karamu individuals compared to two representative individuals homozygous for the orientis and klugii haplotypes. Coding regions are indicated below the plot, with the candidate gene for background colouration yellow indicated. Green triangles represent the top 10 SNPs for background colour in our GWAS. There is evidence for recombination throughout the supergene region, and specifically in the vicinity of yellow, consistent with the hypothesis that orientis ancestry at this locus (i.e., the B allele) is associated with darker colouration in karamu individuals.
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Jana Helsen @helsenjana.bsky.social · 17/01/2025
Centromere evolution isn't a sudden switch! Our study shows centromere transitions are a step-by-step process driven by a combination of drift and selection. Discover how the kinetochore interface shapes this gradual change in our new preprint 🥳 doi.org/10.1101/2025.01.16.633479 🧵(1/8)
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David Toews @davetoews.bsky.social · 14/10/2024
🦉🧪 Questions about high latitude myrtle warblers have been "up in the air" (pun intended) since 1899! @stephszarmach.bsky.social used fancy new geolocators that track light AND barometric pressure to add an unexpected chapter to this tale ......
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German Lagunas-Robles @g-lagunasrobles.bsky.social · 19/09/2024
Our preprint on the unexpected absence of a multiple-queen supergene haplotype in supercolonial populations is up on bioRxiv! We found that the P haplotype is not necessary for supercoloniality in the Formica rufa group, despite its longstanding association with non-supercolonial polygyny.
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Julian Catchen @jcatchen.bsky.social · 18/07/2024
Happy to release Stacks v2.67 today. This release updates process_radtags to make it easier to use SRA data and to filter poly-G (error) runs coming from Nextseq/Novaseq machines + bugfixes. We also added a genotype depth filter to populations #RADseq catchenlab.life.illinois.edu/stacks/
catchenlab.life.illinois.edu
Stacks
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The American Genetic Association @theaga.bsky.social · 13/06/2024
New article: 'The role of conflict in the formation and maintenance of variant sex chromosome systems in mammals' 🔬 From fusions to Y chromosome loss, sex chromosome karyotypes vary widely in mammalian genomes. 1/3
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Susan Johnston @susanjohnston.bsky.social · 21/03/2024
With a link that works 😊
biorxiv.org
The genetic architecture of recombination rates is sexually-dimorphic and polygenic in wild house sparrows (Passer domesticus).
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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Julia Kreiner @jmkreiner.bsky.social · 02/01/2024
Hey ya'll. Our paper on the phenotypic consequences of intraspecific variation in repeat content and genome size was published over the holidays. Check it out when you get back to work :) journals.plos.org/plosgenetics...
journals.plos.org
Quantifying the role of genome size and repeat content in adaptive variation and the architecture of...
Author summary The remarkable and seemingly inconsequential variation in genome size across species has long been an enigma in evolutionary biology. Calling this viewpoint into question, correlations ...
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Mark Hibbins, Great Lakes Swashbuckler @rejectresubmit.bsky.social · 14/12/2023
Excited to share the first paper from my postdoc, using phylogenomics to uncover dynamic genome evolution in Rumex! Featuring @joannarifkin.bsky.social, @bmsacchi.bsky.social, @stepheniwright.bsky.social, and others not on the app! www.biorxiv.org/content/10.1...
biorxiv.org
Phylogenomics resolves key relationships in Rumex and uncovers a dynamic history of independently ev...
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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German Lagunas-Robles @g-lagunasrobles.bsky.social · 21/11/2023
Posting for my colleague Giulia Scarparo and collaborators. Check out their new paper on a supergene that controls for queen miniaturization! Giulia's post attached below. Paper here: www.cell.com/current-biol...
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David Toews @davetoews.bsky.social · 08/11/2023
Steph Szarmach discusses her geolocator work on Alaskan Myrtle warblers! *Spoiler alert*: there are no spoilers! wilsonsociety.org/2023/11/07/g...
wilsonsociety.org
Guest Post: Tracking the Migrations of Alaskan Myrtle Warblers
Standing in a clearing surrounded by black spruce and birch, I raise my binoculars after spotting a quick flash of movement high up in the foliage.
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Tanja Slotte @tanjaslotte.bsky.social · 07/11/2023
Super happy to be awarded a project grant for our Linum supergene and mating system work from the Swedish Research Council, AND a Formas grant on unlocking genetic variation for drought tolerance using landscape genomics in crop wild relatives!
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Dr. Brendan "Doesn't-go-to-Ravenholm" Pinto @drpintothe2nd.bsky.social · 03/11/2023
Mitonuclear sex determination? Empirical evidence from bivalves. academic.oup.com/mbe/advance-...
academic.oup.com
Mitonuclear sex determination? Empirical evidence from bivalves
Abstract. Genetic elements encoded in nuclear DNA determine the sex of an individual in many animals. In certain bivalve lineages that possess doubly uniparenta
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Matthew Hahn @3rdreviewer.bsky.social · 30/10/2023
New from @snaildit.bsky.social and me. We find that popular methods for detecting introgression between sister species (fastsimcoal2, dadi, BPP) all have high false positive rates in biologically realistic settings. www.biorxiv.org/content/10.1...
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Anna Tigano @annatigano.bsky.social · 27/10/2023
Our new paper on the genomic vulnerability of climate change in Kokanee (resident ecotype of sockeye salmon) is out today doi.org/10.1111/eva.... We packed a lot of questions in this paper, and there is something for every taste: climate change, adaptive potential, heat waves,
doi.org
Genomic vulnerability of a freshwater salmonid under climate change
Evolutionary Applications is an open access evolutionary biology journal, covering questions of health, social and economic significance.
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E. Anne Chambers @chamberea.bsky.social · 27/10/2023
Want to use landscape genomics for conservation? Curious about how to apply these methods to individual-based sampling? Not to worry– use algatr! Our new paper w/ co-first author @anushabishop.bsky.social and coauthor Ian Wang is out in MER! More below ⬇️ #OA onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Individual‐based landscape genomics for conservation: An analysis pipeline
Molecular Ecology Resources is a broad journal publishing computer programs, statistical & molecular advances & more for studies in evolution, ecology & conservation.
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Henry North @henrylnorth.bsky.social · 24/10/2023
A polygenic explanation for Haldane’s rule in butterflies www.pnas.org/doi/abs/10.1...
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Julian Catchen @jcatchen.bsky.social · 24/10/2023
I have been having a lot of fun revising private allele analysis in #Stacks from #RADseq data. What are private alleles? Given SNPs in a set of populations, a private allele is found only in a specific population. 1/n
Chromosome genome scan showing private alleles from two species in a hybrid populationZoomed in 1Mbp region showing private alleles having introgressed into hybrid populations (dark blue vertical lines)
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 19/10/2023
Continuously fluctuating selection reveals extreme granularity and parallelism of adaptive tracking www.biorxiv.org/content/10.1101/202…
biorxiv.org
Continuously fluctuating selection reveals extreme granularity and parallelism of adaptive tracking https://www.biorxiv.org/content/10.1101/2023.10.16.562586v1
Temporally fluctuating environmental conditions are a ubiquitous feature of natural habitats. Yet, h
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