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Flávia E. Rius

@flaviaerius.bsky.social
71 followers 88 following 74 posts

Data scientist interested in polygenic risk scores, cancer, and a few unrelated things. #rstats #bioinformatics flaviaerius.com

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Flávia E. Rius @flaviaerius.bsky.social · 8h
I remember asking in a lecture I took during PhD called Immunology of Exercise: what are the most universally pro-health and anti-health factors? Pro-health: exercise Anti-health: cigarrettes
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Theo Priestley @theopriestley.net · 29/09/2026
Every AI CEO sounds like this.
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Georgios Karamanis @karaman.is · 25/09/2026
IKEA names its sofas after Swedish places, and most of its armchairs follow the same rule. IKEA Sweden sells 64 of them right now, and I put every one on a map. Pick a sofa or armchair and see where it comes from! karaman.is/ikea-place-n... #dataviz #maps
 A web page titled "The IKEA place-name map". On the left, a dropdown has MALMKÖPING selected. Below it is a photo of a beige 3-seat sofa priced from 7 295 kr, and it is placed in Flens kommun, Södermanlands län. On the right is a map of Sweden with dots for sofas, armchairs and places that have both. Most dots are in the south, and Älmhult, IKEA's home town, is marked with a red cross.
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Emil Uffelmann @euffelmann.bsky.social · 21/09/2026
New preprint 🧵 Nagelkerke's R² is widely used to report polygenic score performance for binary traits, but it depends on prevalence and case fraction, so you can't compare it across diseases or studies. We derive a simple conversion to the liability scale. 👇
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Sharon Machlis @smachlis.bsky.social · 16/09/2026
3 key skills in the era of software development with generative AI, @wesmckinney.com tells #PositConf2026: Judgment - deciding what's worth doing Taste - recognize what makes it good Agency
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Flávia E. Rius @flaviaerius.bsky.social · 15/09/2026
Chat vs. workflow vs. agent evaluation in a medical evaluation (patient) context, shows that for this context agent means better quality by the lowest cost. Extracted from the great presentation by Timothy Keyes at #positconf2026. #positconf
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Flávia E. Rius @flaviaerius.bsky.social · 15/09/2026
Love the intro video of #positconf2026! Happy to have contributed to a small part of it, by telling my story and my "what if". Congrats to the team for the amazing work!
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Mike Inouye @mikeinouye.bsky.social · 15/09/2026
We are recruiting for a Postdoctoral Researcher in Biomedical AI to open up new frontiers at the interface of genetics, biochemistry and the use of population-scale data to guide development of therapeutics! www.cam.ac.uk/jobs/researc... Come do some blue sky research w/ me & @cfoguet.bsky.social 😁
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Garrick Aden-Buie @grrrck.xyz · 13/09/2026
I’m on my way to #PositConf2026! Stoked to see old friends, make new friends, and show off some of the cool things we’ve built since last year! Here’s a sneak peek: I made a shinychat conf concierge to help you catch all your favorite talks! bit.ly/posit-conf-c...
bit.ly
posit::conf(2026) Schedule Assistant
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Flávia E. Rius @flaviaerius.bsky.social · 10/09/2026
My calendar is ready for #positconf2026 next week! Excited to see what's coming! PS: I'll split in two for some talks, no problem :its-fine-emoji:
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Flávia E. Rius @flaviaerius.bsky.social · 01/07/2026
Note on using Gemini Pro for paper references: First, it hallucinated on the year and journal, making it up for a preprint paper. Second: it got wrong the order of authorship for a second paper with the same team, repeating the order of the first paper. Folks, review your AI results.
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In Preparation @inprep.bsky.social · 26/06/2026
inpreparation.substack.com
Open Science Advocate Develops Scalable Method For Ruining Everyone's Day
TEL AVIV, ISRAEL—In a breakthrough moment for professional disappointment, open science advocate Oded Rechavi demonstrated Tuesday a novel platform capable of ruining the mornings of 56,880…
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Andrew Heiss @andrew.heiss.phd · 17/11/2025
I recently discovered Conventional Comments (conventionalcomments.org) for providing a pseudo-standard set of labels for feedback and just tried it for an article review and it was really helpful to specify issues vs. thoughts vs. suggestions, etc. Hopefully it's helpful for the authors too!
We strongly suggest using the following labels:

praise:	Praises highlight something positive. Try to leave at least one of these comments per review. Do not leave false praise (which can actually be damaging). Do look for something to sincerely praise.
nitpick:	Nitpicks are trivial preference-based requests. These should be non-blocking by nature.
suggestion:	Suggestions propose improvements to the current subject. It’s important to be explicit and clear on what is being suggested and why it is an improvement. Consider using patches and the blocking or non-blocking decorations to further communicate your intent.
issue:	Issues highlight specific problems with the subject under review. These problems can be user-facing or behind the scenes. It is strongly recommended to pair this comment with a suggestion. If you are not sure if a problem exists or not, consider leaving a question.
todo:	TODO’s are small, trivial, but necessary changes. Distinguishing todo comments from issues: or suggestions: helps direct the reader’s attention to comments requiring more involvement.
question:	Questions are appropriate if you have a potential concern but are not quite sure if it’s relevant or not. Asking the author for clarification or investigation can lead to a quick resolution.
thought:	Thoughts represent an idea that popped up from reviewing. These comments are non-blocking by nature, but they are extremely valuable and can lead to more focused initiatives and mentoring opportunities.
chore:	Chores are simple tasks that must be done before the subject can be “officially” accepted. Usually, these comments reference some common process. Try to leave a link to the process description so that the reader knows how to resolve the chore.
note:	Notes are always non-blocking and simply highlight something the reader should take note of.
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Isabella Velásquez @ivelasq3.bsky.social · 17/06/2026
As a previous co-organizer for R-Ladies Seattle, I know how long a little help can go. That’s why I’m so excited that Posit is supporting community conferences and local meetups! Please share this with an organizer who wants to feed folks some pizza while learning about data science tools 🍕
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Emil Hvitfeldt @emilhvitfeldt.bsky.social · 17/06/2026
Come join me for a all new slidecrafting workshop! 2 hours of all new content, teaching you to go from zero to hero in quarto slides! It is free and open to anyone, very minimal quarto knowledge required, we are starting with the basics! pos.it/slide-wrkshp #quarto #slidecrafting
pos.it
Slidecrafting Workshop with Emil Hvitfeldt
This will be a 2-hour workshop (with a short break) led by Emil Hvitfeldt all about making great slides in Quarto! Wed, Aug 12, 2026 12:00 PM EDT
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wenchangyue.bsky.social @wenchangyue.bsky.social · 17/06/2026
10 colour palettes I reach for in research charts — curated, and most are colourblind-safe. Categorical + sequential: Okabe-Ito, Paul Tol, Tableau 10, viridis, cividis, magma. Skip default tab10 and rainbow/jet. Which do you swear by? Anything I'm missing? #DataViz #ColorPalette #SciComm
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Flávia E. Rius @flaviaerius.bsky.social · 19/05/2026
TIL that .callout blocks in quarto can be collapsed using {.callout-note collapse="true"}. So useful when you need a long text like an introduction to be included, but you want to avoid excessive scrolling to get to the main data in the report. #quarto #rstats
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Flávia E. Rius @flaviaerius.bsky.social · 28/04/2026
I love that #rstats introduced me to some social sciences and economics people. The studies I come across by because of this are quite interesting! I would never see any of this in my biomedical sciences bubble.
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Ryan Hernandez @rdhernand.bsky.social · 14/02/2026
Science Bluesky is now much better than Science Twitter is… but I still miss peak pre-pandemic Science Twitter.
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Flávia E. Rius @flaviaerius.bsky.social · 08/04/2026
This benckmark does not express how better Claude Code is than the other models on top. Apparently, the reasoning of Opus 4.6 being better makes all the difference. (I've tested it for some bioinformatics data analysis in the last hour and the difference is brutal, even Sonnet vs. Gemini-any).
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Flávia E. Rius @flaviaerius.bsky.social · 21/03/2026
There is a subtle difference in transforming a vector into a file using writeLines() or write.table(col_names = F, row.names=F): the latter allows quotes in the output. It makes a lot of difference for file paths, for example. #rstats
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Libby Heeren @libbyheeren.bsky.social · 12/03/2026
R/Medicine conf is so good. I'm not in medicine, and it doesn't matter. It's always great!! #rstats
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Flávia E. Rius @flaviaerius.bsky.social · 05/03/2026
OMG the proportion this post took. This is NOT a hateful post for tidyverse. I love tidyverse! It is only a person pov while doing more stuff with python pandas*. As @nrennie.bsky.social pointed out, polars is more similar to the tidyverse.
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Flávia E. Rius @flaviaerius.bsky.social · 04/03/2026
It is much easier to understand python code for data science if you know a bit of base R than if you only know tidyverse. #rstats #python
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Luis D. Verde Arregoitia @liomys.mx · 20/02/2026
English version now available luisdva.github.io/rstats/RRstu...
luisdva.github.io
R is not RStudio
and that’s OK
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Flávia E. Rius @flaviaerius.bsky.social · 20/02/2026
Using quarto with python is a whole new experience. It is *not* a simple switch of languages (if you're an R user like me).
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DMM Journal @dmmjournal.bsky.social · 19/02/2026
We also have a separate programme for the Global South. If your idea is selected, we will bring the event to your region. #BiologistsWorkshops Details: www.biologists.com/workshops/pr...
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Flávia E. Rius @flaviaerius.bsky.social · 18/02/2026
Wow. ✨
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Flávia E. Rius @flaviaerius.bsky.social · 06/02/2026
Is there any buzzfeed-like quiz out there yet to figure out which AI model is the best for you? It would be fun.
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Flávia E. Rius @flaviaerius.bsky.social · 27/01/2026
{ellmer} 10/10 in stability to extract structured from unstructured data using #gemini API. I used type_object() to set the desired output, and json to set the input. I'm still experimenting with LLM API calls, but so far it was much better error-wise than a python script with schemas. #rstats
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Flávia E. Rius @flaviaerius.bsky.social · 27/01/2026
Guys, you need to come up with a better strategy of getting rid of robots. I lose half of my day recognizing buses, bikes and stairs.
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Flávia E. Rius @flaviaerius.bsky.social · 26/01/2026
Creating a package to organize my work, instead of just reloading functions from scripts, was the best thing I did so far this year. #rstats
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Posit @posit.co · 23/01/2026
2 weeks left to take the stage at posit::conf(2026)! 🎤 Share your work on R, Python, open-source, or any topic the community would love. Can't make it to Houston? Apply for our virtual track! It’s a great way to reach the global community. Apply here: posit.co/blog/posit-c... #positconf2026 #rstats
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Eric Topol @erictopol.bsky.social · 22/01/2026
The Shingles vaccine and reduction of dementia: a new natural experiment from Canada replicated 3 others and adds to this week's link to slowing of biological aging. erictopol.substack.com/p/spotlight-...
erictopol.substack.com
Spotlight on the Shingles Vaccine—Again!
Two new studies add to a remarkable body of evidence for benefit
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Flávia E. Rius @flaviaerius.bsky.social · 16/01/2026
If you'd like your files to be ordered by "last modified" in the explorer, you can append the following config to your settings.json: { "explorer.sortOrder": "modified" } Works both in #positron and in #vscode.
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Flávia E. Rius @flaviaerius.bsky.social · 16/01/2026
If you are using independent training and testing sets which need PCA calculation in genomics, be sure to do it using projection and to the same panel, alongside the same parameters (maf, ld and missingness). Otherwise, you are comparing bananas to apples. #genomics #bioinformatics
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Posit @posit.co · 15/01/2026
Speak at posit::conf(2026) and share your R & Python stories! Accepted speakers get: ✨ Travel & lodging help ✨ Free conference pass ✨ Professional coaching Apply by Feb 6 to join us Sept 14-16 in Houston, TX! Submit here: pos.it/conf-talk-2026 #positconf2026 #rstats #pydata
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Flávia E. Rius @flaviaerius.bsky.social · 15/01/2026
3 things I learned from @stephenturner.us workshop on #R pkg development in #Positron - there is a light bulb icon that creates a roxygen template for an R file - available::available("pkgname") checks if the name you want has already been used - {pkgndep} evaluates heaviness of pkg dependencies
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Flávia E. Rius @flaviaerius.bsky.social · 12/01/2026
I use a gist everytime I need to run a few basic #bioinformatics explorations in a new instance, and thought I could share it here so someone could benefit from it too! I have forked it and adapted a bit to my needs. Here it goes: gist.github.com/flaviaerius/...
gist.github.com
Install samtools, bcftools and htslib on linux
Install samtools, bcftools and htslib on linux. GitHub Gist: instantly share code, notes, and snippets.
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Flávia E. Rius @flaviaerius.bsky.social · 09/01/2026
I won't miss this one!
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Stephen Turner @stephenturner.us · 07/01/2026
poisonfrogs: Color Palettes Inspired by Neotropical Poison Frogs laurenoconnelllab.github.io/poisonfrogs/ #Rstats
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Jack Kosmicki @jakphd.bsky.social · 07/01/2026
Really nice work by @nbaya.bsky.social and co. showing that, as expected, individuals whose observed phenotype deviates from their genetically predicted trait are enriched for rare damaging variants in associated genes with said trait. Now to see if embryo selection companies pick up on this 😉
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Flávia E. Rius @flaviaerius.bsky.social · 06/01/2026
Crazy interesting biology! I wonder if there is any phenotypic evidence of this chimerism.
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Totoro @nigelsq.bsky.social · 31/12/2025
#RStats Friends, for those of you who need to work with #RStudio in Windows I've put a survival guide for you here. github.com/eriksquires/...
github.com
GitHub - eriksquires/RStudio_with_Windows
Contribute to eriksquires/RStudio_with_Windows development by creating an account on GitHub.
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Sharon Machlis @smachlis.bsky.social · 16/12/2025
Turn YAML into R and R into YAML with the new {yaml12} #RStats 📦 posit-dev.github.io/r-yaml12/ind... By @t-kalinowski.bsky.social On the 📦 website: "YAML in 2 Minutes: A Gentle Introduction for R Users" posit-dev.github.io/r-yaml12/art...
posit-dev.github.io
Fast YAML 1.2 Parser and Formatter
A fast, correct, safe, and ergonomic YAML 1.2 parser and generator written in Rust. Convert between YAML and simple R objects with full support for multi-document streams, tags, anchors, and aliases. ...
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Stephen Turner @stephenturner.us · 03/12/2025
polars-bio—fast, scalable and out-of-core operations on large genomic interval datasets academic.oup.com/bioinformati... 🧬🖥️🧪 github.com/biodatageeks...
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Stephen Turner @stephenturner.us · 25/11/2024
Tech I'm thankful for blog.stephenturner.us/p/tech-im-th... #rstats 🧬🖥️🧪
blog.stephenturner.us
Tech I'm thankful for (2024)
Data science and bioinformatics tech I'm thankful for in 2024: tidyverse, RStudio, Positron, Bluesky, blogs, Quarto, bioRxiv, LLMs for code, Ollama, Seqera Containers, StackOverflow, ...
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Flávia E. Rius @flaviaerius.bsky.social · 11/11/2025
Tip for formatting text on Google Docs by Gemini *without changing content*: If the text is in one language, use the prompt to format in another language. It worked perfectly for me! Before that, every time I asked it to "format without changing text" it failed. #gemini
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Flávia E. Rius @flaviaerius.bsky.social · 10/11/2025
My talk on #positconf2025 is available on Youtube! Check it out: youtu.be/phh8p2ImBMQ?...
youtu.be
Precision Medicine for All: Using Tidymodels to Validate PRS in Brazil (Flávia Rius) | posit::conf
YouTube video by Posit PBC
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saskiasanderson.bsky.social @saskiasanderson.bsky.social · 06/11/2025
🧬 PRSs in practice (3/5): Higher-risk results = behaviour change? A common concern is that higher-risk polygenic risk scores (PRSs) don’t motivate lifestyle behaviour change. My @nathumbehav.nature.com paper with @mikeinouye.bsky.social addresses this 👉 rdcu.be/eNeKN #Genomics #BehaviourChange
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