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Prof Amy Cain

@flamycain.bsky.social
447 followers 339 following 9 posts

ARC Future Fellow Macquarie University, School of Natural Sciences 🇦🇺 she/her | Functional 🧬,💊discovery, Synbio, 🐛, ♻️| Ex-@sangerinstitute @VertexPharma @Mlw_Programme

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Reposted by Prof Amy Cain
ARC Centre of Excellence in Synthetic Biology @coesb.com.au · 16/07/2026
🦠 A gene resistant to one of our last-resort antibiotics has been found somewhere no one was looking: polluted sediment, not a hospital. Researchers at Macquarie University and The University of Sydney discovered mcr-12, the first ever to be found in an environmental setting. Story: bit.ly/4pwlchC
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Antbiotic resistance found in surprise source - ARC Centre of Excellence in Synthetic Biology
Scientists have found a new source of antibiotic resistance in an unexpected place: polluted freshwater sediment in NSW. Researchers at Macquarie University and The University of Sydney discovered a g...
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ARC Centre of Excellence in Synthetic Biology @coesb.com.au · 01/07/2026
Exciting news for antifungal research and for translating great science into real-world impact. Congratulations to Centre researchers Professor Amy Cain @flamycain.bsky.social, Dr Hue Dinh and the team! 🎉 Read the story: www.coesb.com.au/exclusive-de... @arc-gov-au.bsky.social
coesb.com.au
Exclusive deal to advance therapies for fungal infection - ARC Centre of Excellence in Synthetic Biology
Centre researchers whose work showed cannabis-derived compounds can kill dangerous fungal pathogens have secured a commercial partner to take those findings toward clinical use. Australian life scienc...
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Prof Amy Cain @flamycain.bsky.social · 09/03/2026
Excited to host A/Prof Lars Barquist @lbarquist.bsky.social from @utoronto.ca and @helmholtz-hiri.bsky.social at Macquarie University for a fantastic workshop on RNAseq experimental design and analysis! Thanks to the FSE Multiomics Centre for sponsoring!
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Reposted by Prof Amy Cain
ARC Centre of Excellence in Synthetic Biology @coesb.com.au · 04/03/2026
From battling typhoid to fighting plastic pollution, Professor Amy Cain’s career has been driven by microbial mysteries. 👉 Read our Annual Report story 'How a moth's microbiome could hold the answer to plastic pollution' now: bit.ly/4rfYFou @flamycain.bsky.social
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How a moth's microbiome could hold the answer to plastic pollution
When Associate Professor Amy Cain was just a young girl, her mother introduced her to the idea that her skin was covered with microbes. Some children might have been freaked out by the notion, but you...
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Reposted by Prof Amy Cain
Sandra Reuter @sandrareuter.bsky.social · 20/01/2026
First paper of this year is out now! 📢 Very happy to present work with my collaborators Andrew Whitelaw and Mae Newton-Foot and especially great work from PhD student Kedisaletse Moloto at Stellenbosch University: journals.plos.org/plospathogen...
journals.plos.org
Carbapenem resistant Klebsiella pneumoniae isolates at a tertiary hospital in Cape Town, South Africa, are dominated by specific local clones rather than previously described international lineages
Author summary Carbapenem resistant K. pneumoniae (CRKP) have emerged as a cause of hospital and community acquired infections, posing a significant threat to public health, and have hence been listed...
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Reposted by Prof Amy Cain
Microbiology Society @microbiologysociety.org · 19/12/2025
📢 Senior Editor role opportunity available with the Microbiology Society for the Pathogens & Epidemiology section. This role supports journal strategy, section development & community engagement. More info: Voluntary Opportunities: microb.io/Vacancies
microb.io
Jobs
View the current job vacancies at the Microbiology Society.
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Reposted by Prof Amy Cain
Katie Field @katiefield4.bsky.social · 08/11/2025
1. Postdoc in plant-fungal interactions: jobsite.sheffield.ac.uk/job/Research... 2. Postdoc in molecular plant-microbe interactions: jobsite.sheffield.ac.uk/job/Research... 3. Research technician: jobsite.sheffield.ac.uk/job/Technici... (Pls share!)
jobsite.sheffield.ac.uk
Research Associate: Plant-fungal interactions
Research Associate: Plant-fungal interactions
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Reposted by Prof Amy Cain
ARC Tracker @arc-tracker.bsky.social · 26/10/2025
ARC says Discovery Projects outcomes will be tomorrow (Tuesday). Linkage Projects (2025, round 1) on Wed. Over past ~year, it's often been at about 11am (Canberra). My bot will pick up the change to RMS & post immediately. ARC should email outcomes to lead CIs, but might take an 1hr or so for DPs
Screenshot of tweet from the ARC saying they will announce DP26 outcomes on Tuesday 28th Oct, and LP25r1 outcomes on Wednesday 29th.
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Reposted by Prof Amy Cain
Typas Lab @typaslab.bsky.social · 13/10/2025
Excited to share our preprint led by Carlos Voogdt et al We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera. www.biorxiv.org/content/10.1...
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Prof Amy Cain @flamycain.bsky.social · 21/10/2025
Check out my PhD student Fiona Facey’s first first-author paper on finding microbes that can degrade multiple types of plastics in the Galleria mellonella gut microbiome 👇 enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
enviromicro-journals.onlinelibrary.wiley.com
Characterising the Multiple‐Plastic Degrading Strain of Bacillus subtilis GM_03 From the Galleria mellonella Microbiome
A novel strain of Bacillus subtilis has been isolated from plastic-fed Galleria mellonella larvae, which shows evidence of degradation of both LDPE and PU plastics. Genes potentially associated with ....
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Reposted by Prof Amy Cain
ASM NSW-ACT Branch @asm-nswact.bsky.social · 20/10/2025
🌟 Applications are now open for the 2025 ASM NSW-ACT Branch Summer Student Research Awards! 🌟 Are you an undergrad, Honours, or Masters (Coursework) student? Apply for a $1,500 research award to support a 4-week summer project. Deadline: 5pm, Fri 5 Dec Learn more & apply: asm-nswact.org.au/awards/
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Ronan McCarthy @ronanmccarthy.bsky.social · 29/09/2025
Delighted to share that @evgeniamaslova.bsky.social passed her PhD viva today with only minor corrections. Her project focused on novel models to study wound infection. Thank you to the @nc3rs.bsky.social for funding her PhD and @flamycain.bsky.social and Anthony Tsolaki for being superb examiners.
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Prof Amy Cain @flamycain.bsky.social · 04/09/2025
At the @asm-nswact.bsky.social AGM hosted by our outgoing Chair Karl Hassan and Secretary Tom Jeffries 🫡 Our post AGM speaker @bill-lab.bsky.social giving a fantastic post AGM talk with some eye candy microscopy! Thanks to all who joined!
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Prof Amy Cain @flamycain.bsky.social · 31/08/2025
Come join us on the ASM NSW committee! All you have to do is email back the committee form below!
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Reposted by Prof Amy Cain
ASM NSW-ACT Branch @asm-nswact.bsky.social · 31/08/2025
📢 Reminder: ASM Committee Nominations Are Open! 📝 Nomination form: asm-nswact.org.au/wp-content/u... 📅 AGM details: www.trybooking.com/events/landi... We’d love to see more members getting involved and helping shape the future of ASM. ✨
asm-nswact.org.au
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Australian Museum Eureka Prizes @eurekaprizes.bsky.social · 30/07/2025
@livingseawalls.bsky.social is a finalist in the NSW DCCEEW Eureka Prize for Environmental Research. Learn more: youtu.be/9yrRzgyZqoI #EurekaPrizes @sims-australia.bsky.social @melaniejbishop.bsky.social @cariocamayer.bsky.social @marialvozzo.bsky.social
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Australian Museum Eureka Prizes @eurekaprizes.bsky.social · 31/07/2025
The Fission Chips Team from Macquarie University is a finalist in the @ansto.bsky.social Eureka Prize for Innovative Use of Technology. Learn more: youtu.be/6yf27LdQkhw #EurekaPrizes
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Reposted by Prof Amy Cain
ARC Centre of Excellence in Synthetic Biology @coesb.com.au · 31/07/2025
Ian Paulsen has transformed #syntheticbiology from a niche science in Australia to a national strength. Under his leadership, our Centre has spun out ten startup companies that have raised more than $200 million in venture capital. Join us in congratulating Ian on this fantastic achievement! 🎊
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Reposted by Prof Amy Cain
Melanie Blokesch @mblokesch.bsky.social · 08/07/2025
Water everywhere 😜 - with Mario @feldmanlab.bsky.social & Amy @flamycain.bsky.social at Acinetobacter conference in Niagara Falls
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Lars Barquist @lbarquist.bsky.social · 12/06/2025
Very excited about our latest combining advanced cell culture, transposon-insertion sequencing, and statistical modeling to map Shigella virulence determinants in organoid models. Great collaboration w/ @mldm.bsky.social @sellinlab.bsky.social in @natgenet.nature.com www.nature.com/articles/s41...
nature.com
A scalable gut epithelial organoid model reveals the genome-wide colonization landscape of a human-adapted pathogen - Nature Genetics
A genome-wide screen using human gut epithelial organoids combined with transposon-directed insertion sequencing identifies over 100 Shigella flexneri genes required for epithelial colonization.
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Prof Amy Cain @flamycain.bsky.social · 09/06/2025
I'm excited to present our latest study in @plos.org NTDS, collaborating with @sydney.edu.au and UNSW that uncovers the potent antifungal activity of phytocannabinoids against life-threatening Cryptococcus and tinea/athletes foot fungi: lighthouse.mq.edu.au/article/may-... Reach out for more info!
lighthouse.mq.edu.au
Cannabis extract shows promise as treatment for fungal infections
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Reposted by Prof Amy Cain
Zannah Salter @zannahdu.bsky.social · 25/05/2025
Very pleased to share this preprint! "Characterisation of Ornithobacterium hominis colonisation dynamics and interaction with the nasopharyngeal microbiome in a South African birth cohort" 🧵 www.biorxiv.org/content/10.1...
biorxiv.org
Characterisation of Ornithobacterium hominis colonisation dynamics and interaction with the nasopharyngeal microbiome in a South African birth cohort.
Ornithobacterium hominis is a recently described Gram-negative bacterium that colonises the human nasopharynx and may be associated with poor upper respiratory tract health. Here, we describe the isol...
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Reposted by Prof Amy Cain
ARC Centre of Excellence in Synthetic Biology @coesb.com.au · 08/04/2025
Congratulations to Associate Professor Amy Cain @flamycain.bsky.social of our #MacquarieUniversity node on being awarded The Australian Academy of Science (#AAS) 2025 #GottschalkMedal — in recognition of her pioneering work in the fight against #antibioticresistance 🦠💊
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Mark Webber @webberma.bsky.social · 12/03/2025
Anyone interested in joining us @quadraminstitute.bsky.social as part of @norwichmicro.bsky.social we’re recruiting for group leaders! www.jobs.ac.uk/job/DMF274/g...
jobs.ac.uk
Group Leader (Microbes and Food Safety) at Quadram Institute Bioscience
Start your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top...
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Reposted by Prof Amy Cain
ARC Centre of Excellence in Synthetic Biology @coesb.com.au · 12/03/2025
🎉 Congratulations to Centre startups Levur, Newera Bio, Swan Genomics and Wild Yeast Zoo on securing Australia's Economic Accelerator (AEA) Ignite Grants! Read the full story 👇 bit.ly/3DM9BY2
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Centre startups secure AEA grants - ARC Centre of Excellence in Synthetic Biology
Four startups from the Centre have successfully secured Australia’s Economic Accelerator (AEA) Ignite Grants, providing a shot in the arm for the local synthetic biology ecosystem.NewEra Bio, Levur, S...
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Reposted by Prof Amy Cain
ASM NSW-ACT Branch @asm-nswact.bsky.social · 03/03/2025
🦠 Job Opportunity in Microbiology! 🦠 UNSW Sydney is hiring a Lecturer/Senior Lecturer (Education Focused) in Microbiology! 🎓 📅 Apply by: March 31st, 2025: url.au.m.mimecastprotect.com/s/F9dHCRONg6... Please share with your networks or anyone interested!
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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Reposted by Prof Amy Cain
The Lancet @thelancet.com · 02/03/2025
✨ Exciting new Lancet role ✨ This autumn, our Group is launching an OA journal dedicated to the unique health challenges on the African continent: The Lancet Regional Health—Africa 🌍 To lead this important endeavour, we are searching for an Editor-in-Chief. Find out more & apply ⤵️ bit.ly/3Xp919w
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Editor-in-Chief, The Lancet Regional Health - Africa
Do you enjoy using science to drive change in the world? Would you like to develop and launch an online-only gold open access journal for The Lancet. About our Team The Lancet Regional Health -Africa ...
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ASM NSW-ACT Branch @asm-nswact.bsky.social · 28/01/2025
📣Students and ECRs of Microbiology in NSW! The ASM travel award application deadlines are coming up on the 28th Feb and 17th March 2025. Make sure you apply below: Student Nancy Millis: asm-nswact.org.au/wp-content/u... ECR BD Award: asm-nswact.org.au/wp-content/u...
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Reposted by Prof Amy Cain
ARC Centre of Excellence in Synthetic Biology @coesb.com.au · 19/01/2025
🌍 A global research collaboration, including Macquarie University’s Associate Professor Amy Cain, has been awarded €1 million to combat the growing crisis of antifungal resistance. Congratulations! 👏👏👏 bit.ly/4jkB6YO
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Major Funding Boost for Combating Fungal Infections - ARC Centre of Excellence in Synthetic Biology
An international research collaboration, including Macquarie University's Associate Professor Amy Cain, has received €1 million to tackle the growing global crisis of antifungal resistance. This escal...
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Prof Amy Cain @flamycain.bsky.social · 16/01/2025
Super excited to announce that we’ve successful in an important new NHMRC/JPIAMR grant developing new metal-containing antifungals. Looking forward to working with some fantastic collaborators across Europe! url.au.m.mimecastprotect.com/s/Ur_tCWLVn6...
url.au.m.mimecastprotect.com
Tackling Antifungal Resistance: RAFT Project Secures Major Grant
The RAFT project, a groundbreaking international collaboration, has been awarded a prestigious grant exceeding € 1 million to address the growing crisis of antifungal resistance—a global healthcare ch...
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Prof Amy Cain @flamycain.bsky.social · 11/12/2024
Huge congratulations to my talented PhD student Geraldine Sullivan and amazing MRes student Natasha Delgado who graduated from Macquarie University yesterday - both with VC awards! Feeling proud and grateful to work with such fantastic students - looking forward to watching your careers grow!
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Lars Barquist @lbarquist.bsky.social · 19/11/2024
Are you applying RNA-seq or TraDIS/Tn-seq to antibiotic-treated bacteria? Our paper from earlier this year with @flamycain.bsky.social shows that antibiotic interference with chromosome replication can confound functional genomics analyses! Thread 1/n journals.asm.org/doi/full/10....
journals.asm.org
A method to correct for local alterations in DNA copy number that bias functional genomics assays applied to antibiotic-treated bacteria | mSystems
Altered gene dosage due to changes in DNA replication has been observed under a variety of stresses with a variety of experimental techniques. However, the implications of changes in gene dosage for s...
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Lars Barquist @lbarquist.bsky.social · 19/11/2024
And most of the credit should go to Geri Sullivan for all the hard work, and her PhD supervisor (and excellent collaborator!) @flamycain.bsky.social
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Lars Barquist @lbarquist.bsky.social · 11/01/2024
Very pleased to finally see this out in Genome Biology: we used mixed-effect machine learning to predict CRISPRi guide efficiency, learning more about the system along the way. Work from very talented former PhD student Yanying Yu, now postdoc at Broad Institute. link.springer.com/article/10.1...
link.springer.com
Improved prediction of bacterial CRISPRi guide efficiency from depletion screens through mixed-effec...
CRISPR interference (CRISPRi) is the leading technique to silence gene expression in bacteria; however, design rules remain poorly defined. We develop a best-in-class prediction algorithm for guide si...
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Jessica Blair @jessicamablair.bsky.social · 11/10/2023
Cool new paper from Ian Paulsen and co - Systematic analyses identify modes of action of ten clinically relevant biocides and antibiotic antagonism in Acinetobacter baumannii www.nature.com/articles/s41...
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