Hospital-acquired 'A. baumannii' infections are notoriously hard to treat. A new study shows how these microbes can prolong infection by hiding from antibiotics inside immune cells.

Communications Biology - Gene expression studies in the critical pathogen Acinetobacter baumannii identified the existence of daily rhythms displaying a robust response to light, as well as...

Author summary Acinetobacter baumannii causes life-threatening and often antibiotic-resistant infections thereby posing a global threat. Accordingly, there is an urgent need for alternative treatments...

Bacteroides spp. are Gram-negative, gut commensals that shape the enteric landscape by producing outer membrane vesicles (OMVs) that degrade dietary fibers and traffic immunomodulatory biomolecules. U...

Many antibiotics are ineffective against Gram-negative pathogens such as Pseudomonas aeruginosa because they cannot penetrate the bacterial outer membrane. Here, we show that protein antibiotics calle...

Nature - A new lasso peptide antibiotic exhibits broad-spectrum activity against Gram-negative and Gram-positive bacteria by interfering with bacterial protein synthesis, is unaffected by common...

Pope Francis is being treated in hospital for double pneumonia — but what is this condition, and why might the pope be particularly vulnerable to it?

The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.

Using an arcane law, officials have effectively delayed funding from the National Institutes of Health, leaving medical studies in jeopardy.

Toxin-antitoxin systems make up a branch of the bacterial anti-phage immune system. Here, Johannesman et al demonstrate that some phages have co-opted an orphan antitoxin to counter a DNA ADP-ribosylt...

Its architect's daughter has cystic fibrosis—and benefits from a "miracle drug" backed by an agency he's attacking.

Vasodilation is a crucial protective response to inflammation and infection. Endothelial cells control vasodilation through the bioavailability of eNOS-produced nitric oxide (NO), and the generation o...

The Trump administration has put a hold on all federal financial grants and loans, affecting tens of billions of dollars in payments.

St. Jude Careers is hiring a Senior Scientist-Immunology, Vaccinology, Infection in Memphis, Tennessee. Review all of the job details and apply today!

The authors describe a new crosstalk between a globally disseminated carbapenem resistance plasmid and clinical enterobacteria clones. This crosstalk provides a fitness advantage to the plasmid-carryi...