Sign in

Dr François Gravey

@fgravey.bsky.social
45 followers 49 following 20 posts

🧫 Clinical Microbiologist | MD, PhD 🔬 Research: #Genomics of MDR bacteria, #AMR & #OneHealth. 📍 CHU Caen, France. Sharing microbiology news, resistance cases & my publications. 🇫🇷🇬🇧

PostsRepliesMedia
Dr François Gravey @fgravey.bsky.social · 20/12/2025
🩸 Sepsis: Can "Time to Positivity" (TTP) be a free, immediate diagnostic tool? Our study (in vitro + 151k vials) suggests TTP predicts species before identification. Thread on clinical rules ⤵️ doi.org/10.1016/j.di... #ClinMicro #IDSky #Sepsis #MedSky
doi.org
Redirecting
142
Reposted by Dr François Gravey
Nature Microbiology @natmicrobiol.nature.com · 12/12/2025
#NatMicroPicks AMR plasmid evolution over a century! ⭕🧬🦠💊 Plasmids from 1917–1954 reveal over a century of evolution shaped by antibiotic industrialization #MicroSky www.science.org/doi/10.1126/...
science.org
Pre- and postantibiotic epoch: The historical spread of antimicrobial resistance
Plasmids are now the primary vectors of antimicrobial resistance, but our understanding of how human industrialization of antibiotics influenced their evolution is limited by a paucity of data predati...
0185
Dr François Gravey @fgravey.bsky.social · 11/12/2025
🧪 Lab life question! What antibiogram methods do you use in your lab? 🔹 Disk diffusion? 🔹 MIC strips ? 🔹 Automated systems ? 🔹 Broth microdilution ? 🔹 Or something else? Let’s share and compare! 👇 #Microbiology #LabLife #AntimicrobialResistance #ClinicalMicrobiology #OneHealth
100
Dr François Gravey @fgravey.bsky.social · 11/12/2025
One of my favorite podcast 🫶 let's have a look 👀 next monday !
021
Dr François Gravey @fgravey.bsky.social · 10/12/2025
Are horses a reservoir for high-risk Enterobacter? 🐴🏥 Our new #Genomics study reveals the presence of human clones ST114 & ST171 in equine samples. Essential data for #OneHealth & #AMR monitoring. 📄 Read Harel et al.: doi.org/10.1371/jour... #MicroSky #VetSci @plosone.org @anses-fr.bsky.social
A phylogenetic tree showing the genetic diversity of 34 equine isolates alongside reference genomes. To the right of the tree, a matrix displays the resistome and phenotype: colored dots indicate the presence of specific antibiotic resistance genes (like beta-lactams and quinolones), and a heatmap shows phenotypic resistance levels. The chart highlights that Enterobacter hormaechei strains (ST114 and ST171) carry the most acquired resistance genes compared to Huaxiibacter and Lelliottia species.An alluvial diagram comparing two identification methods for equine bacterial strains. The left axis shows results from MALDI-TOF, and the right axis shows results from Whole Genome Sequencing (rMLST). Colored bands connecting the two sides illustrate significant discrepancies: many strains initially identified as Enterobacter spp. or "Not determined" by MALDI-TOF were reclassified as Lelliottia, Huaxiibacter, or Rahnella by genomic analysis.
132
Reposted by Dr François Gravey
AnniZLab: [🦠, 🧬 , ✨] @annizlab.bsky.social · 06/12/2025
Reference genome choice compromises population genetic analyses - a problem for microbes too! Our lab is designing a tool to automatically choose references for input samples using features like phylogeny of reads to existing references. Any thoughts🤩? 🧪🦠🧬🖥️ #microsky www.cell.com/cell/abstrac...
cell.com
Reference genome choice compromises population genetic analyses
Using a species-specific reference genome significantly improves the accuracy of population genetic analyses, as exemplified by mapping gray fox sequence data to genomes of several canid species. Mapp...
4257
Reposted by Dr François Gravey
sylvain Brisse @sylvainbrisse.bsky.social · 27/06/2025
The New Invasion - @fgravey.bsky.social presenting the epidemiology of carbapenem-resistant bacteria in Normandy, France
021
Dr François Gravey @fgravey.bsky.social · 20/05/2025
In France, despite medical biology contributing to 70% of medical diagnoses, a decreasing number of medical residents are choosing this specialty. However, dedicated teaching, presented in an engaging and interactive manner, has proven effective 😀 pubmed.ncbi.nlm.nih.gov/39991819/
pubmed.ncbi.nlm.nih.gov
[How to promote medical biology to medical students: interest of interactive clinical cases in biological laboratory] - PubMed
Despite its central role in modern medicine, medical biology tends to attract fewer future physicians. The reasons for this disinterest are varied: a lack of awareness about the specialty among studen...
000
Dr François Gravey @fgravey.bsky.social · 20/05/2025
Really agree with this post, amazing podcast, learned so much, thank you very much @cmicomms.bsky.social
140
Reposted by Dr François Gravey
womensartbluesky.bsky.social @womensartbluesky.bsky.social · 17/05/2025
Portrait of Otelia Cromwell, the first African American woman to receive a Ph.D. from Yale University, 1926, by contemporary US painter Jennifer Packer #WomensArt
06215850
Reposted by Dr François Gravey
Ursula Hofer @hoferu.bsky.social · 01/05/2025
Academically, I know there are massive problems with access to adequate antibiotics in LMICs, but looking at infection burden and sales of relevant antibiotics, this article estimates only 6.9% of CRGN infections are treated properly. Truly shocking.
132
Reposted by Dr François Gravey
Ursula Hofer @hoferu.bsky.social · 30/04/2025
I feel seen.
121
Dr François Gravey @fgravey.bsky.social · 29/04/2025
Really pleased to see our students doing their first oral communications at the rencontres normandes de microbiologie today organized in Evreux. Bravo Tarcila and Blandine ! @universite-caen.bsky.social @inserm.fr
123
Reposted by Dr François Gravey
The New Yorker @newyorker.com · 28/04/2025
Barry Blitt’s cover for this week’s issue, “The First Hundred Days.” #NewYorkerCovers nyer.cm/ysrCZ47
413273796603
Dr François Gravey @fgravey.bsky.social · 17/04/2025
This morning with my team we talked about the @angelahuttner.bsky.social pilot program in @cmicomms.bsky.social journal in which some very relevant reviewers could be add in the acknowledgments or perhaps among authors ! At the unanimity, this is an amazing idea 🙂
110
Reposted by Dr François Gravey
ESCMID @escmid.bsky.social · 15/04/2025
Attendees can receive certificates for attending or presenting at #ESCMIDGlobal 2025. For more info, visit the congress webpage: ow.ly/sHfa50VzNO7 Please note, you can only claim credit points once, so be sure to claim them all at the end.
072
Reposted by Dr François Gravey
Nature Reviews Microbiology @natrevmicro.nature.com · 16/04/2025
Our May issue is now LIVE!🎊 www.nature.com/nrmicro/volu... 🔹Antibiotic-recalcitrant Salmonella during infection 🔸The consequences of SARS-CoV-2 within-host persistence 🔹Shigella sonnei: epidemiology, evolution, pathogenesis, resistance & host interactions 🔸Hepatitis B and D virus entry
033
Dr François Gravey @fgravey.bsky.social · 16/04/2025
Very interesting discovery from an Institut Pateur team about interactions between bacterial and eukaryotic DNA cells. #bacteria #science #insitutpateur Sequence-dependent activity and compartmentalization of foreign DNA in a eukaryotic nucleus | Science www.science.org/doi/10.1126/...
science.org
Sequence-dependent activity and compartmentalization of foreign DNA in a eukaryotic nucleus
In eukaryotes, DNA-associated protein complexes coevolve with genomic sequences to orchestrate chromatin folding. We investigate the relationship between DNA sequence and the spontaneous loading and a...
000
Dr François Gravey @fgravey.bsky.social · 15/04/2025
Thank you very much to @drneilstone.bsky.social for your very inspiring talk this morning about the scientific presence on social medias at #escmidglobal2025. You have been heard, this is my first message on Bluesky. Let’s see how it goes 🙂
0325
Reposted by Dr François Gravey
The Lancet Infectious Diseases @thelancetinfdis.bsky.social · 15/04/2025
New reserach The WHO Bacterial Priority Pathogens List 2024: a prioritisation study to guide research, development, and public health strategies against antimicrobial resistance www.thelancet.com/journals/lan...
thelancet.com
The WHO Bacterial Priority Pathogens List 2024: a prioritisation study to guide research, development, and public health strategies against antimicrobial resistance
The 2024 WHO BPPL is a key tool for prioritising research and development investments and informing global public health policies to combat AMR. Gram-negative bacteria and rifampicin-resistant M tuber...
11611
Reposted by Dr François Gravey
Angela Huttner @angelahuttner.bsky.social · 15/04/2025
Great talk by Ursula Hofer @hoferu.bsky.social, editor-in-chief of @thelancetinfdis.bsky.social, on #predatorypublishing. So many horrible things to learn. 😥 #ESCMIDGlobal #IDSky
editor-in-chief Ursula Hofer speaks about predatory publishing at ESCMID Global in Vienna.
0117
Reposted by Dr François Gravey
CMI Communications @cmicomms.bsky.social · 15/04/2025
Another great talk! @drneilstone.bsky.social discusses how social media can serve you & communicate your research! Some great slides breaking down an effective posting strategy! 🚀 #ESCMIDGlobal #IDSky #clinmicro
1236