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Dr Emma S Chambers

@emmaschambers.bsky.social
1.8K followers 912 following 37 posts

Senior Lecturer in Immunology based at Blizard Institute, QMUL. My research focussed on life course immunology and the influence of age and sex, and life-course events such as menopause on the immune system in health and disease.

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Dr Emma S Chambers @emmaschambers.bsky.social · 19/04/2026
Two members of my lab are presenting their work at the #BSID2026 in Manchester, both on Tuesday. Cameron Ferguson will be presenting his DEBRA UK funded work on drug repurposing at 9.40am and Shuwei Zhang will be presenting her work on building a 3D model of aged skin at 1pm. Looking forward to it
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Dr Emma S Chambers @emmaschambers.bsky.social · 14/04/2026
Exciting news! I am doing Pint of Science 2026!! I will be presenting my work in a pub on Tuesday 19th May. My talk will be on menopause and sex difference in immunity in the session called "Mind the Gender Gap". Tickets for the event can be found below: pintofscience.co.uk/event/mind-t...
pintofscience.co.uk
Mind the Gender Gap
Medical research has historically ignored and underfunded issues that affect gender minorities, tonight Dr Emma Chambers and Dr Alison Berner will share th…
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Dr Emma S Chambers @emmaschambers.bsky.social · 13/04/2026
Interested in asthma, in vitro models and immunology? Well I have a PhD that would be perfect for you! www.findaphd.com/phds/program... Come and perform cutting edge bioengineering using a model of an asthma lung using a unique organ-on-a-chip model to test novel anti-inflammatory therapies.
findaphd.com
FindAPhD : EPSRC Centre for Doctoral Training in Next Generation Organ on a Chip Technology (COaCT) at Queen Mary University of London
Apply for a PhD: EPSRC Centre for Doctoral Training in Next Generation Organ on a Chip Technology (COaCT) at Queen Mary University of London
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British Society for Immunology @britsocimm.bsky.social · 03/02/2026
🧬 How do we move immunosenescence research forward? Join us in Guildford this May to explore next generation technologies for studying immune ageing. The event is taking place on 20 and 21 May 2026. Submit an abstract and be part of the discussion! 🔗 bit.ly/3YGD7VW
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Dr Emma S Chambers @emmaschambers.bsky.social · 02/02/2026
I am delighted to introduce the 'ImmunoPause' consortium. This is a collection of immunologists who are working on understanding how the immune system changes during the menopause. An important yet understudied research area. immunopause.my.canva.site#home
immunopause.my.canva.site
Home
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Wendy Bickmore @wbickmor.bsky.social · 01/02/2026
At a time when the UK should be capitalising on its global reputation as a great place to do science, this is an enormous own goal. I am so sorry for all those who jobs are going to be impacted.
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Dr Emma S Chambers @emmaschambers.bsky.social · 23/01/2026
Delighted to have contributed to this very cool monocyte resolution paper. Do take a look :)
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Journal of Experimental Medicine @jem.org · 12/01/2026
Estrogen influences class-switched memory B cell frequency only in humans with two X chromosomes. From @hlpeks.bsky.social, @emmaschambers.bsky.social, @bcellsrosser.bsky.social, Ciurtin et al. 👉 rupress.org/jem/article/... 📘 In 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
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British Society for Immunology @britsocimm.bsky.social · 22/12/2025
How do we better measure and target immune ageing? Registrations are now open for 'New technologies to advance immunosenescence research'. Join us on 20 and 21 May 2026 in Surrey to hear from experts in immune ageing and next generation technologies 🔬 bit.ly/3YGD7VW
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Dr Emma S Chambers @emmaschambers.bsky.social · 06/12/2025
Interested in developing an asthma organ-on-a-chip model? Then your luck is in! As I have a funded PhD as part of the COaCT PhD programme www.cpm.qmul.ac.uk/cdt/projects...
cpm.qmul.ac.uk
PhD Projects 2026: QMUL Centre for Predictive in vitro Models
The Centre for Predictive in vitro Models (CPM) represents multidisciplinary research focusing on the development and use of predictive in vitro models at Queen Mary University of London. This incorpo...
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Lizzy Rosser @bcellsrosser.bsky.social · 02/12/2025
Loving #BSI25, especially @ciurtinlab.bsky.social and @emmaschambers.bsky.social highlighting our paper in @jem.org is one of #ArthritisUK top research output of ‘25! If you have 5 minutes, give us a vote (number 5) below, sex differences in the immune system: www.arthritis-uk.org/our-research...
arthritis-uk.org
Research Highlight of the Year
Arthritis UK Research Highlight of the Year: celebrate the outstanding work that’s made a real impact over the past year.
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Dr Emma S Chambers @emmaschambers.bsky.social · 02/12/2025
Great to see a slide in the immunosenescence session advertising our exciting meeting next year #BSI25
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Dr Emma S Chambers @emmaschambers.bsky.social · 29/11/2025
I am off to the @britsocimm.bsky.social Congress this week. I will be speaking about menopause and monocytes in the sex differences nsession on Tuesday and chairing the skin session on Thursday. Looking forward to seeing all my immunology friends :) #BSI25
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Dr Emma S Chambers @emmaschambers.bsky.social · 23/10/2025
An exciting programme of talks today. Come and see my poster (17) about menopause as an immune ageing event.
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Barts Charity @bartscharity.bsky.social · 18/10/2025
This #WorldMenopauseDay we're proud to talk about how we supported innovative research into menopause and women's immunity - led by @emmaschambers.bsky.social at the @blizardinstitute.bsky.social @qmul.bsky.social bit.ly/492IYeG
qmul.ac.uk
Hormone replacement therapy may help restore immunity in menopausal women
https://www.qmul.ac.uk
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Dr Emma S Chambers @emmaschambers.bsky.social · 18/10/2025
Happy World Menopause Day. Reminder that as well as the impact of menopause on physical and mental wellbeing. Menopause also seems to be an immune-ageing event www.qmul.ac.uk/media/news/2...
qmul.ac.uk
Hormone replacement therapy may help restore immunity in menopausal women
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Immune Sex Differences @sexdiffimmunity.bsky.social · 15/10/2025
Surprisingly, it is not yet obvious to all researchers and funding agencies that sex and gender matter in research, and should be recorded and addressed properly. So we wrote it authors.elsevier.com/c/1lxSmbah1w...
authors.elsevier.com
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Eric Topol @erictopol.bsky.social · 09/10/2025
Hormone replacement therapy helps restore immune function in menopausal women, reducing inflammaging and preserving monocyte function. open-access onlinelibrary.wiley.com/doi/10.1111/... Extends what I previously summarized from immune system clocks erictopol.substack.com/p/new-anti-a...
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Roel De Maeyer @roeldemaeyer.bsky.social · 09/10/2025
New paper alert #immunosky 🚨 What happens to our immune systems as we get older? What happens after the menopause? Turns out monocytes are actually quite important in their own right! Check out our paper in Aging Cell now: onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Age‐Associated Inflammatory Monocytes Are Increased in Menopausal Females and Reversed by Hormone Replacement Therapy
Post-menopausal females (> 64 years) have an increase in frequency of inflammatory monocyte populations with defective phagocytosis as compared to pre-menopausal (< 40 years) females. Hormone Replace...
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Dr Emma S Chambers @emmaschambers.bsky.social · 09/10/2025
I am so proud to say that our paper is now available at Aging Cell. There is a paucity of data as to how the menopause impacts your immune system, and the aim of this study was to investigate the impact of the menopause on monocyte phenotype and function. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Age‐Associated Inflammatory Monocytes Are Increased in Menopausal Females and Reversed by Hormone Replacement Therapy
Post-menopausal females (> 64 years) have an increase in frequency of inflammatory monocyte populations with defective phagocytosis as compared to pre-menopausal (< 40 years) females. Hormone Replace....
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Dr Emma S Chambers @emmaschambers.bsky.social · 16/09/2025
This afternoon I am speaking at @emds2025.bsky.social. Chatting monocytes, ageing and menopause :) Looking forward to an exciting meeting
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British Society for Immunology @britsocimm.bsky.social · 01/09/2025
📣 Abstract submissions for #BSI25 are CLOSING SOON! Don't miss your chance to share your research — submit today. 🗓️Deadline: Midnight, Weds 3 Sept 🔗Submit here: bit.ly/3UfF6i5
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tovah-shaw-lab.bsky.social @tovah-shaw-lab.bsky.social · 12/08/2025
I am recruiting for a postdoc that wants to work on an exciting project on gut macrophages, TGFb signalling, and colon cancer! Please see the link for details - elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
elxw.fa.em3.oraclecloud.com
Postdoctoral Research Associate
We are looking for a talented and enthusiastic postdoctoral researcher to join the Shaw lab to investigate identify the regulatory function of NRROS/LRRC33 in gastrointestinal macrophage development a...
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Prof Sian Henson @drsianh.bsky.social · 23/06/2025
New output from the CELLO Network. Article highlighting how metabolic dysfunction underpins ageing and disease. Read the full open-access article 👉 link.springer.com/article/10.1... #Ageing #Metabolism #CellBiology #SystemsBiology
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Dr Emma S Chambers @emmaschambers.bsky.social · 23/06/2025
You get to listen to me talk about menopause and immunity :)
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Lizzy Rosser @bcellsrosser.bsky.social · 20/06/2025
GET YOUR APPLICATION IN NOW! Couldn’t recommend this lab more #sciencebffs ♥️
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Immune Sex Differences @sexdiffimmunity.bsky.social · 13/05/2025
Come join us this fall in Paris
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Matthew Sinton 🏳️‍🌈 @mcsinton.bsky.social · 24/04/2025
Who's ready for another @thestemvillage.bsky.social Immunology Seminar Series? If you haven't seen these before, we invite LGBTQ+ immunologists to present online to the wider immunology community. If you'd like to present or attend, please drop a mention below #immunosky 🧪 #academicsky
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Dr Emma S Chambers @emmaschambers.bsky.social · 02/04/2025
If you have wondered how age, sex and even the menopause influences monocyte phenotype and function. Then our new preprint is for you www.biorxiv.org/content/10.1...
biorxiv.org
Age-associated inflammatory monocytes are increased in menopausal females and reversed by Hormone Replacement Therapy
Biological sex is a crucial, but poorly understood variable in age-related susceptibility to infections and chronic inflammation, inflammageing. Monocytes are important immune cells responsible for in...
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Journal of Experimental Medicine @jem.org · 26/03/2025
Great coverage of the recent JEM paper by @hlpeks.bsky.social, @emmaschambers.bsky.social, @bcellsrosser.bsky.social, Coziana Ciurtin, and colleagues. See the original paper here: rupress.org/jem/article/...
rupress.org
Estrogen influences class-switched memory B cell frequency only in humans with two X chromosomes | Journal of Experimental Medicine | Rockefeller University Press
Sex hormones and chromosomes work in tandem to impact immune responses, with estrogen influencing class-switched memory B cell frequency exclusively in ind
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Dr Emma S Chambers @emmaschambers.bsky.social · 25/03/2025
Super excited to have contributed to this great paper led by @bcellsrosser.bsky.social @arrdept-ucldom.bsky.social showing that Oestrogen influences B cell class switching. rupress.org/jem/article/...
rupress.org
Estrogen influences class-switched memory B cell frequency only in humans with two X chromosomes | Journal of Experimental Medicine | Rockefeller University Press
Sex hormones and chromosomes work in tandem to impact immune responses, with estrogen influencing class-switched memory B cell frequency exclusively in ind
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John Connelly @connellybioeng.bsky.social · 18/03/2025
We have a new PhD position open in the lab! Interested in the intersection between cell mechanics and protein metabolism in scar formation, then have a look. tinyurl.com/4s7wduhu
tinyurl.com
Dissecting the role of lysosomal exocytosis in keloid scar pathogenesis at Queen Mary University of London on FindAPhD.com
PhD Project - Dissecting the role of lysosomal exocytosis in keloid scar pathogenesis at Queen Mary University of London, listed on FindAPhD.com
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Dr Emma S Chambers @emmaschambers.bsky.social · 14/03/2025
I had a lovely trip to my daughter's class today, to tell them all about our biological army, the immune system, for science week. I got such lovely thank you cards from the class :)
Text saying "thank you for teaching me about phagocytosis"Thank you cards with immune cells drawn on by children
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Dr Emma S Chambers @emmaschambers.bsky.social · 24/01/2025
I made myself an inspirational mug out of some recent grant feedback
Mug that is being held up and says on the side "solid application a d track record but .... Not stellar
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Waggoner Lab @labwaggoner.bsky.social · 22/01/2025
Menopause: Time to increase funding for study of a life stage experienced by half of humanity www.nature.com/articles/d41... Emerging therapies to prolong ovarian life and revisiting hormone replacement therapy could change women’s health @lynnepeeps.bsky.social www.nature.com/articles/d41...
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John Connelly @connellybioeng.bsky.social · 22/01/2025
We are super excited to share our newest publication on modelling immune responses in human skin! Hats off to the amazing work of Sarah Hindle during her PhD and all our collaborators! @emmaschambers.bsky.social doi.org/10.1002/advs...
doi.org
Replicating Dynamic Immune Responses at Single‐Cell Resolution within a Microfluidic Human Skin Equivalent
This study describes the development of a vascularized microfluidic skin equivalent, which supports the delivery of circulating immune cells and replication of dynamic inflammatory responses. Single-...
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Madhvi Menon @madhvimenon.bsky.social · 16/01/2025
🚨 The Menon lab is hiring a postdoc! Interested in mucosal immunology? Come join our team to study lung-infiltrating B cell dynamics in COPD & other chronic lung diseases @ukri.org @lydiabeckeriii.bsky.social Please help spread the word #ImmunoSky www.jobs.manchester.ac.uk/Job/JobDetai...
jobs.manchester.ac.uk
Research Associate in Mucosal Immunology :Manchester
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Emma Stoye @emmastoye.bsky.social · 14/01/2025
Nature is keen to find out how scientists are using Bluesky and whether it has become their go-to soc media platform. Do you use Bluesky? Has it replaced X for you? Tell us about it: www.nature.com/articles/d41...
nature.com
Has Bluesky replaced X for scientists? Take Nature’s poll
The research community has flocked to the social-media platform Bluesky. Tell us about your experience.
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Neil McCarthy @neilemccarthy.bsky.social · 06/01/2025
A good start to 2025! We found that IsoDGR protein damage promotes lung inflammation in old mice, but can be successfully treated using antibody therapy? Might the same approach also work in humans? 👀 onlinelibrary.wiley.com/doi/10.1111/... @blizardinstitute.bsky.social @emmaschambers.bsky.social
onlinelibrary.wiley.com
Immunotherapeutic targeting of aging‐associated isoDGR motif in chronic lung inflammation
Accumulation of isoDGR-damaged proteins in aged lung tissues leads to macrophage infiltration and chronic inflammation. Anti-isoDGR antibodies treatment clears isoDGR proteins and reduces inflammatio...
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Dr Louisa James @louisakjames.bsky.social · 19/12/2024
***Fully funded PhD position*** @blizardinstitute.bsky.social with myself and Prof Gavin Giovannoni to investigate CD40 signalling in Epstein Barr Virus-infected B-cells in people with multiple sclerosis. Please spread the word! www.findaphd.com/phds/project...
findaphd.com
CD40 ligand and EBV-infected B-cells in patients with multiple sclerosis at Queen Mary University of London on FindAPhD.com
PhD Project - CD40 ligand and EBV-infected B-cells in patients with multiple sclerosis at Queen Mary University of London, listed on FindAPhD.com
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Dr Emma S Chambers @emmaschambers.bsky.social · 27/11/2024
This week I am at the @BTSrespiratory Winter Meeting #BTSWinter2024. I am looking forward to discussing my new work on the influence of old age on asthma immunephenotype tomorrow morning at 8.50am in the discovery science session.
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Dr Emma S Chambers @emmaschambers.bsky.social · 18/11/2024
Really cool 3D-printed skin research from John Connelly's lab at the Blizard Institute, QMUL. www.biorxiv.org/content/10.1...
biorxiv.org
Replicating dynamic immune responses at single-cell resolution within a microfluidic human skin equivalent
The intricate immunological functions of human skin involve the interplay between multiple different cell types as well as dynamic trafficking of leukocytes in and out the tissue, both of which are ex...
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Dr Emma S Chambers @emmaschambers.bsky.social · 09/11/2024
My lab contributed a small part to this new paper in Aging Cell. doi.org/10.1111/acel...
doi.org
Multiple outcomes of the germline p16INK4a mutation affecting senescence and immunity in human skin
(a) In the skin fibroblasts are a key source of SASP production, with melanocytes having significantly less production. In healthy individuals, senescent fibroblasts play a major role in attracting T...
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Dr Emma S Chambers @emmaschambers.bsky.social · 20/10/2024
I am so excited to start my new @Barts_Charity funded project investigating how menopause and HRT impacts upon immunity. But we are in need of volunteers to help with the study :)
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Dr Emma S Chambers @emmaschambers.bsky.social · 30/01/2024
Just published! My first last author paper! Showing that vitamin D inhibits inflammatory cytokine production from senescent dermal fibroblasts via inhibition of p38-MAPKinase pathway doi.org/10.1111/acel...
doi.org
Vitamin D3 inhibits p38 MAPK and senescence‐associated inflammatory mediator secretion by senescen...
Aging Cell is an open access geroscience journal addressing the biology of aging, from molecular mechanisms of aging to age-related disease.
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Dr Emma S Chambers @emmaschambers.bsky.social · 04/12/2023
On my way to Belfast. I am chairing the @CARINAnetwork ageing and immunity session tomorrow and also my student Ana has a poster on Wed evening (P-202) about ageing, inflammation and monocytes #BSI23
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Dr Emma S Chambers @emmaschambers.bsky.social · 30/09/2023
My new preprint has just been published showing how individual characteristics can influence immune responses to COVID vaccinations www.medrxiv.org/content/10.1...
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