Post-menopausal females (> 64 years) have an increase in frequency of inflammatory monocyte populations with defective phagocytosis as compared to pre-menopausal (< 40 years) females. Hormone Replace...

Biological sex is a crucial, but poorly understood variable in age-related susceptibility to infections and chronic inflammation, inflammageing. Monocytes are important immune cells responsible for in...

Immune dysfunction increases with age owing to cellular senescence and low-grade inflammation, processes that drive each other during ageing. This Review discusses the potential of therapeutic approac...