Our paper is now out, opioid use in rats increases microglia density, affects morphology, and it's related to brain volume changes. link.springer.com/article/10.1...
link.springer.com
Effects of morphine self-administration on brain structure and microglial phenotypic diversity in the absence of neuronal loss in male Wistar rats - Psychopharmacology
Rationale Opioid addiction, including morphine use, is a major public health crisis in the U.S. It has been associated with brain volume changes in reward-related regions, neuronal loss, and neuroinfl...