Sign in

Eder Zavala

@ederzavala.bsky.social
491 followers 264 following 95 posts

Applied mathematician investigating endocrine rhythms • UKRI Future Leaders Fellow • Modelling stress, metabolism, fertility, sleep, inflammation, wearables • Immigrant 🇲🇽🇯🇵🇬🇧 • mbg-lab.org

PostsRepliesMedia
Eder Zavala @ederzavala.bsky.social · 16/09/2026
A new Research Highlight featuring our work has just been published in @natrevendo.nature.com www.nature.com/articles/s41...
nature.com
Monitoring corticosteroid levels in primary aldosteronism - Nature Reviews Endocrinology
Nature Reviews Endocrinology - Monitoring corticosteroid levels in primary aldosteronism
052
Eder Zavala @ederzavala.bsky.social · 12/09/2026
Very interesting work. www.biorxiv.org/content/10.6...
biorxiv.org
Hormone oscillations preserve cellular responsiveness to future physiological demands
Living organisms must sense and adapt to physiological demands of varying intensity, requiring cells to remain responsive over time. While continuous changes in hormone concentrations communicate thes...
020
Eder Zavala @ederzavala.bsky.social · 10/09/2026
🚨 New paper alert! "Regulation of ultradian pulsatility and stress responses in the human hypothalamic–pituitary–adrenal axis" This work offers a theoretical framework for understanding how the stress response encodes dynamic behaviour in HPA axis hormones. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
<em>Journal of Neuroendocrinology</em> | BSN Journal | Wiley Online Library
The hypothalamic–pituitary–adrenal (HPA) axis is a vital neuroendocrine system that maintains homeostasis by regulating stress hormone secretion through tightly controlled circadian and ultradian rhy...
051
Reposted by Eder Zavala
Manchester Centre for Biological Timing @biologicaltimemcr.bsky.social · 09/09/2026
New paper from Eder Zavala's team at the CfBT Regulation of ultradian pulsatility and stress responses in the human hypothalamic–pituitary–adrenal axis onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com
<em>Journal of Neuroendocrinology</em> | BSN Journal | Wiley Online Library
The hypothalamic–pituitary–adrenal (HPA) axis is a vital neuroendocrine system that maintains homeostasis by regulating stress hormone secretion through tightly controlled circadian and ultradian rhy...
032
Reposted by Eder Zavala
Science Magazine @science.org · 31/08/2026
Applying a minimally invasive microdialysis system, researchers capture nuanced patterns in aldosterone levels over 24 hours in patients with primary aldosteronism, which could inform timelier diagnostic strategies. Learn more in #ScienceTranslationalMedicine: scim.ag/4xZGMOm
scim.ag
Tissue corticosteroid rhythms are dysregulated predominantly during sleep in primary aldosteronism
Ambulatory 24-hour microdialysis reveals disrupted corticosteroid rhythms in primary aldosteronism.
0152
Eder Zavala @ederzavala.bsky.social · 26/08/2026
Delighted to share our new study, published today in Science Translational Medicine! We combined dynamic hormone profiling with computational analysis to reveal that Primary Aldosteronism is characterised by disrupted patterns of hormonal secretion. www.science.org/doi/10.1126/...
1102
Eder Zavala @ederzavala.bsky.social · 26/08/2026
Our Mathematical Biomedicine Group has a new website! Come on in and have a peek: mbg-lab.org More exciting news very soon...
050
Reposted by Eder Zavala
Omar Rivasplata @omarrivasplata.bsky.social · 03/08/2026
📢 The Department of Computer Science at The University of Manchester is hiring a Lecturer or Senior Lecturer in AI/Machine Learning ✨ Further details in the LinkedIn job advert: www.linkedin.com/jobs/view/44...
linkedin.com
The University of Manchester hiring Lecturer or Senior Lecturer in Artificial Intelligence/Machine Learning in Manchester, England, United Kingdom | LinkedIn
Posted 4:49:38 PM. The Department of Computer Science seeks to strengthen and expand its research in AI &amp; Machine…See this and similar jobs on LinkedIn.
042
Eder Zavala @ederzavala.bsky.social · 25/06/2026
Unfortunately this is the future of “I did my own research”.
000
Reposted by Eder Zavala
Addison's Disease Self Help Group (ADSHG) @addisonsdisease.bsky.social · 29/05/2026
It’s #AddisonsDiseaseDay - a day for everyone who is affected by Addison’s disease & adrenal insufficiency to join together to raise awareness & celebrate this incredible community 🎉 This year our theme is ‘Turn Awareness into Action’. Find out more ➡️ loom.ly/Fl2cSE4 (1/9)
Graphic announcing Addison’s Disease Day 2026 with the theme “Turn Awareness Into Action.” 

The design features a woman wearing an Addison’s Disease Self-Help Group t-shirt standing in front of ivy-covered walls, alongside bold text, celebratory graphics and the Addison’s Disease Day 29 May logo.
11711
Eder Zavala @ederzavala.bsky.social · 19/05/2026
🚨 New paper alert! We combined high frequency automated microdialysis with mathematical modelling to understand dynamic HPA axis responses to heart surgery in children. Dynamic adrenal response of children to cardiac surgery and cardiac catheterisation academic.oup.com/jcem/article...
academic.oup.com
The dynamic adrenal response of children to cardiac surgery and cardiac catheterisation
AbstractContext. The hypothalamic-pituitary-adrenal (HPA) axis is the key homeostatic system regulating the response to surgical stress. Imbalances in HPA
020
Reposted by Eder Zavala
Division of Neuroscience @dns-uom.bsky.social · 14/05/2026
The next seminar in our series is on Wednesday 27th May at 2pm, presented by Dr Michele Nardin of HHMI Janelia, Virginia, USA and hosted by @ederzavala.bsky.social of Division of Diabetes, Endocrinology & Gastroenterology. As ever, details on poster - all welcome! 🧠#neuroscienceseminar
042
Eder Zavala @ederzavala.bsky.social · 07/04/2026
Delighted to learn our group has been awarded #ICN2026 Travel Grants from BSN @bsneuroendo.bsky.social. Looking forward to present our latest work modelling the human HPA axis dynamics. Thank you BSN for the continued support! www.congre.co.jp/icn2026/inde... @belindombard.bsky.social
congre.co.jp
ICN2026 NAGOYA JAPAN -The International Congress of Neuroendocrinology- [26-29 July 2026, WINC AICHI (Aichi Industry and Labor Center)]
This is the website for ICN2026 which will be held at WINC AICHI(Aichi Industry & Labor Center),Nagoya, Japan on 26-29 July 2026.
021
Reposted by Eder Zavala
Division of Neuroscience @dns-uom.bsky.social · 02/04/2026
The next seminar in our series is on Wednesday 15th April at 2pm, presented by Dr Enrico Amico of @unibirmingham.bsky.social and hosted by @ederzavala.bsky.social of Division of Diabetes, Endocrinology & Gastroenterology. As ever, details on poster - all welcome! 🧠#neuroscienceseminar
001
Eder Zavala @ederzavala.bsky.social · 05/03/2026
Very interesting animal physiology study on the differential regulation of the stress response in the Mexican axolotl. www.nature.com/articles/s41...
nature.com
The adrenal stress response involves distinct dynamics of both cortisol and corticosterone in the axolotl salamander - Lab Animal
This study examines adrenal stress responses and injury signals in axolotl, showing that corticosterone dominates after amputation, while cortisol, which rises with handling stress, is the primary glu...
010
Eder Zavala @ederzavala.bsky.social · 18/02/2026
Grant deadline approaching fast.
010
Eder Zavala @ederzavala.bsky.social · 10/02/2026
🚨 The Gibbs lab at Manchester is advertising a PDRA and a Technician post (3 yrs). The project combines murine models of inflammatory disease with analysis of human samples to delineate how daily rhythms in glucocorticoids direct the anti-inflammatory potential of the immune system. (1/2)
jobs.manchester.ac.uk
Research Associate in Circadian Immunology:Oxford Road
We are seeking an enthusiastic and highly motivated Post Doctoral Research Associate to join the Gibbs Lab, which studies the role of the circadian clock in regulating immunity.
110
Reposted by Eder Zavala
Manchester Centre for Biological Timing @biologicaltimemcr.bsky.social · 02/02/2026
New publication for the CfTB! Time of day of cardiac surgery and postoperative outcomes in the UK: a secondary analysis of linked national datasets associationofanaesthetists-publications.onlinelibrary.wiley.com/share/VKP7YS...
associationofanaesthetists-publications.onlinelibrary.wiley.com
Time of day of cardiac surgery and postoperative outcomes in the UK: a secondary analysis of linked national datasets
You have to enable JavaScript in your browser's settings in order to use the eReader.
012
Eder Zavala @ederzavala.bsky.social · 02/02/2026
🚨 Last week to apply! The PDRA will lead on projects modelling the mechanisms behind hormonal rhythm misalignment. Ideal for a candidate with a background in mathematics, physics, computer science or similar. Deadline is 6th Feb. www.jobs.manchester.ac.uk/Job/JobDetai...
jobs.manchester.ac.uk
Research Associate Mathematical Biomedicine:Oxford Road
The applicant should have experience with mathematical modelling using ODEs and/or DDEs, parameter estimation methods and HPC simulations. The applicant should be familiar with dynamical systems theory, network analysis and Bayesian inference frameworks.
010
Eder Zavala @ederzavala.bsky.social · 30/01/2026
ENDOTRAIN Doctoral Network (MSCA DN): 19 fully funded PhD positions in digital endocrinology, adrenal disorders, AI and wearable health technology: www.findaphd.com/phds/program...
findaphd.com
FindAPhD : ENDOTRAIN Doctoral Network (MSCA DN): 19 fully funded PhD positions in digital endocrinology, adrenal disorders, AI and wearable health technology at University of Bergen
Apply for a PhD: ENDOTRAIN Doctoral Network (MSCA DN): 19 fully funded PhD positions in digital endocrinology, adrenal disorders, AI and wearable health technology at University of Bergen
052
Eder Zavala @ederzavala.bsky.social · 28/01/2026
What could possible go wrong... Palantir, an American tech giant best known for its work with US defence and intelligence agencies, also works in the UK where it won a £330 million contract to develop data platforms that integrate information held across separate NHS trusts.
000
Reposted by Eder Zavala
Serge Ahmed @sergeahmed.bsky.social · 27/01/2026
Reward as drive reduction, the return! This opinion piece on the explanatory and unifying power of the homeostatic reinforcement learning framework is amazingly accessible, despite its technical nature, and extremely insightful 👏 www.sciencedirect.com/science/arti... 1/2
14715
Eder Zavala @ederzavala.bsky.social · 23/01/2026
Productive time in Bergen for the kickstart of the ENDOTRAIN doctoral network. A EU Horizon Marie Curie funded consortium to revolutionise Digital Endocrinology.
040
Reposted by Eder Zavala
John Morgan @johnmorgan3.bsky.social · 20/01/2026
Shift the govt wants at UKRI - and its new CEO wants - already in evidence as it pauses some funding calls. UKRI says it is in a "period of transition" after spending review, as it aligns more funding to "national priorities" and economic growth. www.researchprofessionalnews.com/rr-news-uk-r...
researchprofessionalnews.com
UKRI pauses several funding calls amid priorities shake-up - Research Professional News
“Period of transition” at funding agency sees some Medical Research Council funding opportunities on hiatus
124
Eder Zavala @ederzavala.bsky.social · 21/01/2026
Worth reading the full transcript of Mark Carney’s speech. It’s time we stop living within a lie. www.weforum.org/stories/2026...
weforum.org
Davos 2026: Special address by Mark Carney, PM of Canada
Canadian PM Mark Carney stressed the end of the rules-based international order and urged middle powers to act together to counter the great power rivalry.
020
Eder Zavala @ederzavala.bsky.social · 09/01/2026
🚨 Job alert! Looking for a postdoc to lead on projects modelling the mechanisms behind hormonal rhythm misalignment. Ideal for a candidate with a background in mathematics, physics, computer science or similar. Application deadline is 6th Feb. Full details: www.jobs.manchester.ac.uk/Job/JobDetai...
jobs.manchester.ac.uk
Research Associate Mathematical Biomedicine:Oxford Road
The applicant should have experience with mathematical modelling using ODEs and/or DDEs, parameter estimation methods and HPC simulations. The applicant should be familiar with dynamical systems theory, network analysis and Bayesian inference frameworks.
041
Reposted by Eder Zavala
Iain Johnston @mitomaths.bsky.social · 09/01/2026
1. Apply for one of the positions below (lab or theory) by Jan 18th 2. Learn interdisc skills and discover cool new things about how mitochondria move and socialise 3. Explore some of Norway's beautiful nature (both the below, Rundemanen and Gullfjellet, <10km from work)
058
Reposted by Eder Zavala
European Journal of Endocrinology @eurojendo.bsky.social · 05/01/2026
EJE Rising Stars Reviewer Board and Mentorship Programme - now open for applications! Apply now 👉 www.ese-hormones.org/about-us/gov... Deadline: Friday 16 January, 2026
034
Eder Zavala @ederzavala.bsky.social · 19/12/2025
🚨 New PhD alert! Thanks to our recent EU MSCA Doctoral Network award ENDOTRAIN, you can be part of Europe’s first doctoral network in digital endocrinology and help transform the diagnosis and management of adrenal disorders through cutting-edge digital tools. www.findaphd.com/phds/project... (1/2)
findaphd.com
Mathematical modelling of the cross-talk interactions between the HPA axis and the renin-angiotensin system at The University of Manchester on FindAPhD.com
PhD Project - Mathematical modelling of the cross-talk interactions between the HPA axis and the renin-angiotensin system at The University of Manchester, listed on FindAPhD.com
153
Eder Zavala @ederzavala.bsky.social · 13/12/2025
A lovely commentary on our latest paper where we challenged the notion of the popular Cortisol Awakening Response (CAR) as a response to awakening: "That which we call cortisol awakening response, by any other word would smell as sweet" doi.org/10.1093/brai...
050
Eder Zavala @ederzavala.bsky.social · 06/12/2025
Behind the Alan Turing building hosting the Department of Mathematics at @manchester.ac.uk
020
Eder Zavala @ederzavala.bsky.social · 04/12/2025
Great few days at Cambridge Newton Institute for Mathematical Sciences scoping meeting on computation, modelling, and statistical analysis of physiological and clinical brain signals for real-time classification and prediction. Here’s Belinda presenting her poster! www.newton.ac.uk/event/ooew10/
130
Reposted by Eder Zavala
Dan Jagger @auditorynerves.bsky.social · 25/11/2025
The human brain goes through distinct phases in life, with turning points at ages 9, 32, 66 & 83, scientists have revealed. ~4,000 people up to the age of 90 had scans to reveal the connections between their brain cells. We "peak" in our early 30s ... 🧪🧠 #neuroskyence www.bbc.com/news/article...
bbc.com
Four pivotal ages in your brain's development revealed in new scientific study
Brain scans on thousands of people reveal the dramatic shifts the brain goes through between birth and death.
42510
Eder Zavala @ederzavala.bsky.social · 28/11/2025
Looking forward to contribute to this event in Cambridge. We will discuss computational and statistical frameworks for processing physiological and clinical data, emphasising predictive accuracy and clinical interpretability. Talks will be streamed so you can tune in. www.newton.ac.uk/event/ooew10/
newton.ac.uk
Scoping meeting: Computation, modelling, and statistical analysis of physiological and clinical brain signals for real-time classification and prediction - Isaac Newton Institute
Shaping the future of real-time physiological and brain signal analysis — from mathematical models to bedside applications. This scoping meeting brings...
010
Eder Zavala @ederzavala.bsky.social · 25/11/2025
Very excited to join the Manchester CfBT and collaborate on multidisciplinary projects ranging from cellular timers and circadian clocks to human physiology and health.
030
Reposted by Eder Zavala
Division of Neuroscience @dns-uom.bsky.social · 17/11/2025
The next event in our seminar series is on Weds 26th November at 2pm. Presented by @ederzavala.bsky.social hosted by Prof Timothy Brown of Division of Diabetes, Endocrinology & Gastroenterology. Details on poster - all welcome! 🧠 #neuroscienceseminar #neuroscience #manchesterneuroscience
043
Eder Zavala @ederzavala.bsky.social · 15/11/2025
We need to speak out more about the realities of immigration and added value that we as immigrants bring to the country. It is vital to counteract misinformation, and if statistical evidence won't cut it, anecdotical evidence may.
061
Eder Zavala @ederzavala.bsky.social · 10/11/2025
Last few days to apply for these 2 fully funded PhD positions in my new group @manchester.ac.uk! Deadline this Saturday 15th Nov.
044
Reposted by Eder Zavala
Journal of Neuroendocrinology @jne-editor.bsky.social · 06/11/2025
📢 NEW early view article! Chronic circadian disruption in female mice induces a long-term alteration of the preovulatory LH surge. 🐁 Authors: Simonneaux M, Simonneaux V. onlinelibrary.wiley....
032
Eder Zavala @ederzavala.bsky.social · 04/11/2025
Autumn colours in Birmingham.
040
Reposted by Eder Zavala
Kat Holt @katholt.bsky.social · 03/11/2025
Apart from the AI junk part… the notion that one should not offer a potential mechanistic explanation for an observation, without first spending years & (unavailable) $$ trying to test possibilities before sharing the observation with others (who may be better equipped to investigate the mechanism)…
2218
Eder Zavala @ederzavala.bsky.social · 02/11/2025
Two weeks left to apply for 2 PhD positions in my group in Manchester. Suitable for maths / computer science / engineering graduates to work on ambitious interdisciplinary projects in digital endocrinology. Contact me for informal enquiries before the deadline on 15th Nov.
010
Reposted by Eder Zavala
Madeleine Kördel @mkoerdel.bsky.social · 15/10/2025
📣 Excited to share that my first paper is now published! 📄"Metabolic state shapes cortisol reactivity to acute stress: A systematic review and meta-analysis of metabolic and hormonal modulators" You can find the full paper here: doi.org/10.1016/j.yn...
doi.org
Redirecting
44312
Reposted by Eder Zavala
Eric Topol @erictopol.bsky.social · 28/10/2025
Longer walks linked with less mortality and cardiovascular risk compared with short bouts of physical activity @annalsofim.bsky.social www.acpjournals.org/doi/10.7326/...
acpjournals.org
Step Accumulation Patterns and Risk for Cardiovascular Events and Mortality Among Suboptimally Active Adults | Annals of Internal Medicine
Background: Although physical activity recommendations increasingly consider daily step counts, it remains unclear whether step accumulation patterns—short versus sustained longer bouts—affect associa...
520458
Eder Zavala @ederzavala.bsky.social · 20/10/2025
Britain has been stripped of the spaces that allow for true social integration. But it’s easier for politicians to blame ‘outsiders’ www.theguardian.com/world/commen...
theguardian.com
A-level English, voluntary work, delayed citizenship: it’s Labour’s Orwellian Two Minutes Hate for immigrants | Nesrine Malik
It’s easier for politicians to blame others than to face the truth: Britain has been stripped of the spaces and opportunities that allow for true social integration, says Guardian columnist Nesrine Ma...
010
Eder Zavala @ederzavala.bsky.social · 16/10/2025
🚨 I’ve got some exciting news! I have two PhD positions available in my group to advance Digital Endocrinology at @manchester.ac.uk Please help disseminate widely (application deadline 15th Nov): 1. Modelling hormonal dynamics in the human HPA axis. www.findaphd.com/phds/project... (1/2)
findaphd.com
(EPSRC CASE) Modelling hormonal dynamics in the human HPA axis at The University of Manchester on FindAPhD.com
PhD Project - (EPSRC CASE) Modelling hormonal dynamics in the human HPA axis at The University of Manchester, listed on FindAPhD.com
146
Eder Zavala @ederzavala.bsky.social · 16/10/2025
It's the same with computer code and other STEM areas. Who would have thought the demise of civilisation wouldn't be at the hands of an evil Terminator-style sentient AI, but the much more mundane laziness and carelessness of its early human operators.
010
Eder Zavala @ederzavala.bsky.social · 14/10/2025
Happy to announce that from 1st Dec I will join the University of Manchester @manchester.ac.uk as a UKRI Future Leaders Fellow @ukri.org, where my group will develop a new theoretical framework for Digital Endocrinology. I'm also looking forward to explore such a beautiful city! 🐝 (1/2)
1172
Eder Zavala @ederzavala.bsky.social · 08/10/2025
Just had a very exciting couple of days for the kickstart of UKRI Future Leaders Fellows cohort 9 in Glasgow. Truly impressed by the breadth, originality and quality of fellowship ideas 👌 A lot to live up to.
050