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Annals of Internal Medicine

@annalsofim.bsky.social
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Annals publishes content to inform medical professionals and society, advance standards of medical research, and improve the health of people worldwide.

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Annals of Internal Medicine @annalsofim.bsky.social · 29/09/2026
A randomized trial found that supervised physical therapy and education led to greater short-term improvements in knee pain, function, muscle strength, and recovery than a self-directed exercise program among young adults with ongoing symptoms after ACL reconstruction. bit.ly/4jo2V4N
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Annals of Internal Medicine @annalsofim.bsky.social · 22/09/2026
NEW: Alcohol consumption in the U.S. declined modestly in 2024 after reaching elevated levels during and after the #COVID19 pandemic. #GenZ showed notable decreases in alcohol use and Millennials experienced the greatest reductions in heavy drinking. Read the full study: bit.ly/4hG7Eh2
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Annals of Internal Medicine @annalsofim.bsky.social · 15/09/2026
New research found that people exposed to medetomidine reported severe sedation, distinct withdrawal symptoms, and difficulties with treatment. Researchers say greater awareness, surveillance, and clinical guidance are needed to address this emerging public health concern. bit.ly/4r9qXSZ
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Annals of Internal Medicine @annalsofim.bsky.social · 08/09/2026
NEW: A systematic review found that hospital-based interventions to improve outpatient follow-up for alcohol use disorder (AUD) after discharge show mixed results. bit.ly/4zHkh2i
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Annals of Internal Medicine @annalsofim.bsky.social · 01/09/2026
A prospective cohort study found that higher vitamin B12 levels in mothers and fathers before conception were associated with a lower risk for birth defects. Additionally, mothers with adequate folate levels in early pregnancy had a lower predicted prevalence of birth defects. bit.ly/4qEL5MA
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Annals of Internal Medicine @annalsofim.bsky.social · 25/08/2026
Updated VA/DoD guidelines for adult overweight and #obesity management recommend assessing health risks using #BMI alongside waist circumference and integrating medications, including #GLP1 therapies, when appropriate. Read the full synopsis for free here: bit.ly/4xpAesw
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Annals of Internal Medicine @annalsofim.bsky.social · 19/08/2026
In a new commentary, Aaron E. Carroll, MD, MS @aaronecarroll.bsky.social and David Atkins, MD, MPH argue that the recent cuts to the #AHRQ threaten the future of health care quality and #PatientSafety in the United States. Read here: bit.ly/45BwMik
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Annals of Internal Medicine @annalsofim.bsky.social · 18/08/2026
A study of more than 8,400 adults aged 70 and older found that those with persistently elevated levels of NT-proBNP, a marker of #HeartStress, had a higher risk for #CardiovascularDisease and death. Read here: bit.ly/4xEY7Mu
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Annals of Internal Medicine @annalsofim.bsky.social · 11/08/2026
A randomized trial found that patients with painful hallux rigidus (#arthritis of the big toe joint) who underwent first metatarsophalangeal joint (MTPJ) arthrodesis reported substantially less walking pain after 12 months compared with watchful waiting. bit.ly/3Uadn5n
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Annals of Internal Medicine @annalsofim.bsky.social · 04/08/2026
The @acpimphysicians.bsky.social Immunization Committee reviewed the 2026 AAFP and ACOG immunization schedules and has unanimously voted to support these guidelines. Read the commentary and view the AAFP and ACOG vaccine schedules here: bit.ly/3UbKPIF
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Annals of Internal Medicine @annalsofim.bsky.social · 28/07/2026
In a new commentary, Robert B. Shpiner, MD, argues that growing reliance on #AI for health advice reflects deeper problems in the health care system, including barriers to accessing care, administrative burdens, and communication challenges. Read here: bit.ly/4vZSw21
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Annals of Internal Medicine @annalsofim.bsky.social · 21/07/2026
A subanalysis of an open-label, phase 2b study found that olorofim, a first-in-class orotomide antifungal agent, showed efficacy in patients with disseminated coccidioidomycosis (DCM), a rare complication of Valley Fever, who have limited or no effective treatment options. bit.ly/3TMTd12
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Annals of Internal Medicine @annalsofim.bsky.social · 14/07/2026
A new study analyzing U.S. insurance claims data found that people with #Type2Diabetes who started GLP-1 receptor agonists had a modestly higher rate of ischemic optic neuropathy, a condition causing sudden vision loss, compared with those taking SGLT2 or DPP-4 inhibitors. bit.ly/4bsJB1B
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Annals of Internal Medicine @annalsofim.bsky.social · 07/07/2026
Researchers from Columbia University Irving Medical Center found that reducing sleep by just 1.5 hours per night for six weeks was associated with modest increases in body weight, waist circumference, and sedentary time among adults with elevated cardiometabolic risk. bit.ly/4bw2JM6
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Annals of Internal Medicine @annalsofim.bsky.social · 30/06/2026
A study of over 2.5 million adults found that that same day coadministration of the #COVID19 and flu #vaccines was not associated with increased risk of serious adverse events compared with getting the #FluVaccine alone. bit.ly/4eMaKPn
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Annals of Internal Medicine @annalsofim.bsky.social · 23/06/2026
A pragmatic trial examined whether a comprehensive nurse-led #telehealth program could improve outcomes for patients with poorly controlled #Type2Diabetes in a fee-for-service setting. Read more here: bit.ly/4gBurdN
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Annals of Internal Medicine @annalsofim.bsky.social · 16/06/2026
A new living clinical guideline from @acpimphysicians.bsky.social recommends #semaglutide and #tirzepatide as first-line options when initiating pharmacologic treatment with lifestyle modifications for weight management for nonpregnant adults with obesity. bit.ly/4gmbICO
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Annals of Internal Medicine @annalsofim.bsky.social · 09/06/2026
NEW: Findings from a target trial emulation did not indicate that #GLP1 RA use in early #pregnancy increases the risk for pregnancy loss, abnormal fetal growth, or major birth defects. bit.ly/4oBlW4F
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Annals of Internal Medicine @annalsofim.bsky.social · 02/06/2026
NEW: A study found that many adults who fall into “normal” or “overweight” #BMI categories may still meet criteria for clinical #obesity, a broader term that combines body measurements with evidence of obesity-related health conditions. bit.ly/4uRinJU
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Annals of Internal Medicine @annalsofim.bsky.social · 26/05/2026
NEW: Many patients could pay less for generic drugs by purchasing directly from the Mark Cuban Cost Plus Drug Company instead of using employer-sponsored insurance. bit.ly/4dBCjZJ
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Annals of Internal Medicine @annalsofim.bsky.social · 19/05/2026
In a new position paper, @acpimphysicians.bsky.social says the Centers for Medicare and Medicaid Services (CMS) should reform #MedicareAdvantage to protect patient health and realign the plan option with its original purpose. Read now: bit.ly/4v1sXO8
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Annals of Internal Medicine @annalsofim.bsky.social · 12/05/2026
A randomized controlled trial of 98,000 adults over two decades found that a single screening #sigmoidoscopy significantly reduced #ColorectalCancer risk, especially in men. bit.ly/48UYGb9
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Annals of Internal Medicine @annalsofim.bsky.social · 05/05/2026
A new multicenter randomized trial found that hospitalized patients receiving a low-volume bowel preparation regimen for inpatient #colonoscopy achieved bowel cleansing quality comparable to higher-volume regimens. bit.ly/4tRW1XV
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Annals of Internal Medicine @annalsofim.bsky.social · 21/04/2026
NEW: A randomized trial found that proximal hypoglossal nerve stimulation (pHGNS), an implanted therapy for obstructive sleep apnea, reduced breathing interruptions during sleep and improved daytime sleepiness. bit.ly/4sKvlXO
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Annals of Internal Medicine @annalsofim.bsky.social · 17/04/2026
At this morning’s #IM2026 plenary session, authors of three breaking scientific articles on #AI scribes, #obesity medications and body composition, and #mammography screening presented their research to an impressive crowd. Head to Annals.org to read the full texts of all the articles presented.
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Annals of Internal Medicine @annalsofim.bsky.social · 16/04/2026
We are excited to be in San Francisco for @acpimphysicians.bsky.social Internal Medicine Meeting 2026! We will be sharing highlights from the meeting to keep attendees and readers informed about important sessions and events. Stay tuned for important updates and fun photos from the meeting. #IM2026
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Annals of Internal Medicine @annalsofim.bsky.social · 07/04/2026
A new study found that the SaFETy score, a firearm-specific risk screening tool, can accurately predict #firearm violence risk among young adults treated in #EmergencyDepartments. bit.ly/3NRMWim #ThisIsOurLane
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Annals of Internal Medicine @annalsofim.bsky.social · 31/03/2026
NEW: The commonly prescribed antidepressant fluvoxamine significantly reduced #longCOVID fatigue, while the diabetes drug #metformin showed no benefit. Although longer-term effects remain unknown, fluvoxamine may offer a viable treatment option for long COVID fatigue. bit.ly/4dlAxxj
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Annals of Internal Medicine @annalsofim.bsky.social · 24/03/2026
A new systematic review of 31 studies found that increasing fluid intake and following a diet low in salt and animal protein may help prevent recurrent #KidneyStones. Several medications, including thiazide diuretics, alkali therapy, and allopurinol, may also be helpful. bit.ly/3PFEPpo
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Annals of Internal Medicine @annalsofim.bsky.social · 17/03/2026
NEW: A national survey estimates that nearly 30 million U.S. adults acquired #firearms after the pandemic, newly exposing about 9 million adults and 6.6 million children to firearms in their home. Read the study for free here: bit.ly/4uzr6As #ThisIsOurLane #GunViolence #FirearmViolence
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Annals of Internal Medicine @annalsofim.bsky.social · 10/03/2026
In a position paper, @acpimphysicians.bsky.social outlines barriers that people with disabilities face when entering and advancing in the medical profession. ACP’s recommendations call for greater #accessibility in medical schools, training programs, and clinical environments. bit.ly/46QBOZc
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Annals of Internal Medicine @annalsofim.bsky.social · 03/03/2026
New @acpimphysicians.bsky.social #RSV practice points recommend adults 75 and older receive a protein subunit RSV #vaccine, and those aged 60 to 74 with conditions like heart disease, diabetes, kidney or lung disease, or other comorbidities should consider RSV vaccination. bit.ly/4rNPEnK
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Annals of Internal Medicine @annalsofim.bsky.social · 24/02/2026
NEW: Updated #COVID19 vaccine practice points from @acpimphysicians.bsky.social recommend adults over age 65 and those aged 18-64 at increased risk for COVID-19 should receive the updated 2025-2026 mRNA-based COVID-19 #vaccine. Read the guidelines for free: bit.ly/47azxYS
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Annals of Internal Medicine @annalsofim.bsky.social · 17/02/2026
NEW: Between 2021–2023, 1 in 6 older adults used telehealth, and nearly half of all mental health visits occurred virtually. Researchers warn that rolling back #Medicare telehealth flexibilities could disrupt care for medically vulnerable adults. bit.ly/4aq5vRH
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Annals of Internal Medicine @annalsofim.bsky.social · 10/02/2026
A new ethics policy paper from the @acpimphysicians.bsky.social argues that referring to physicians as “providers” undermines the ethical foundation of the patient‑physician relationship and fails to reflect physicians’ training, responsibilities, and professional role. bit.ly/4cmbj1f
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Annals of Internal Medicine @annalsofim.bsky.social · 03/02/2026
A new modeling study suggests women vaccinated against HPV could undergo cervical cancer screening far less often. The findings indicate that women vaccinated between ages 12 and 24 could be screened just two or three times in their lifetime. Read the study here: bit.ly/4auvNn6
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Annals of Internal Medicine @annalsofim.bsky.social · 28/01/2026
In an editorial, Jeanne Marrazzo, MD, MPH, CEO of @idsainfo.bsky.social, explains the critical role of CDC data surveillance in light of a recent audit that found almost half of CDC public databases halted updates in 2025. bit.ly/4tniUTB
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Annals of Internal Medicine @annalsofim.bsky.social · 27/01/2026
NEW: An audit of routinely updated CDC public databases found that 46% of these databases stopped publishing updates in 2025. The authors warn that these health data gaps could impact public health guidance and trust. Read now: bit.ly/4qN25j4
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Annals of Internal Medicine @annalsofim.bsky.social · 20/01/2026
A cohort study found that 58% of people infected with #Mpox during the 2022 outbreak still had lingering symptoms 11–18 months later. Most were appearance‑related, but some experienced ongoing effects on physical function or daily life. Read the full study for free: bit.ly/3LJa2qf
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Annals of Internal Medicine @annalsofim.bsky.social · 13/01/2026
NEW: A novel tool predicts long-term risk of dying from prostate cancer, helping doctors interpret PSA results more accurately. Tested on over 200K men, it could help doctors tailor screening and treatment to individual risk and life expectancy. Read now: bit.ly/4sEYG7k
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Annals of Internal Medicine @annalsofim.bsky.social · 06/01/2026
NEW: A study of more than 84,000 adults with type 2 #diabetes found that those starting treatment with sodium–glucose cotransporter-2 inhibitors have a slightly lower risk of developing diabetic foot disease compared to those taking glucagon-like peptide-1 receptor agonists. bit.ly/4sr1pBd
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Annals of Internal Medicine @annalsofim.bsky.social · 01/01/2026
As the new year begins, Annals remains committed to publishing evidence-based research that clinicians and patients can trust. Follow along on social media in the coming weeks as we shine a spotlight on some of the most impactful articles published in the past year. bit.ly/4qolRki
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Annals of Internal Medicine @annalsofim.bsky.social · 30/12/2025
A large cohort study found that statins lower mortality and major cardiovascular events in adults with type 2 diabetes, even for those with low predicted heart disease risk. The findings suggest that statins may have broader protective value than previously assumed. Read here: bit.ly/4j9jfo9
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Annals of Internal Medicine @annalsofim.bsky.social · 25/12/2025
Happy holidays from everyone at Annals of Internal Medicine!
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Annals of Internal Medicine @annalsofim.bsky.social · 24/12/2025
The strength of Annals of Internal Medicine depends largely on the ability and effort of many hundreds of reviewers. We offer our gratitude and thanks to all reviewers! Find a full list here: bit.ly/4b98UGu
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Annals of Internal Medicine @annalsofim.bsky.social · 23/12/2025
A new review found that high-THC products may offer modest short-term relief for #ChronicPain, while CBD-only products show no clear benefit. However, side effects like dizziness and nausea were common. Read the review here: bit.ly/4p8ndyz  #THC #CBD #Cannabis
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Annals of Internal Medicine @annalsofim.bsky.social · 16/12/2025
A review found that cutting #SaturatedFat can lower mortality and heart disease risk for people at high #cardiovascular risk. The greatest benefit occurred when saturated fats were replaced with polyunsaturated fats, which reduced nonfatal heart attacks. Read more: bit.ly/4aCvRlx
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Annals of Internal Medicine @annalsofim.bsky.social · 09/12/2025
NEW: A systematic review found that #GLP1 receptor agonists have little or no effect on the risk for obesity-related cancers. The findings offer insights into the safety of GLP-1RAs and suggest no clear signal of increased #cancer risk. bit.ly/4oITSuw
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Annals of Internal Medicine @annalsofim.bsky.social · 02/12/2025
A new systematic review and meta-analysis of 20 randomized controlled trials shows #corticosteroids probably reduce short-term mortality in severe non-COVID-19 pneumonia & ARDS without raising infection risk. Read more at Annals.org: f.mtr.cool/wbqdfbszmg
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Annals of Internal Medicine @annalsofim.bsky.social · 25/11/2025
NEW: Neighborhoods near #cannabis stores saw a 12% increase in cannabis-related ER visits compared to those farther away. The findings suggest that restrictions on the overall number of cannabis retail stores and store concentrations could offer #PublicHealth benefits. f.mtr.cool/droonbhkju
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