iiinova — where your digital self keeps evolving

Diego Javier Zea @diegozea.bsky.social · 19/08/2026

1/7 Two busy weeks around AlphaConformers: last week I presented it at #JuliaCon Global 2026; this week, our preprint is out on bioRxiv. The question behind it: can structural information help AlphaFold explore alternative protein conformations? 🧵

Here's the image of the apo-form, which serves as the query, alongside the holo-form, the target, along with the closest AlphaConformer model for the holo form, illustrating a successful example.

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JuliaHub @juliahub.bsky.social · 03/12/2025

Join us for a deep dive into JuliaC, the new toolchain for building executables and shared libraries from Julia code. Learn how to create compact binaries and integrate Julia with #C, #C++, #Python, and more. juliahub.com/events/build... #JuliaLang #EmbeddedSystems #TechnicalComputing

juliahub.com

JuliaC: A New Tool for Building Julia Binaries - Event - JuliaHub

Explore how JuliaC builds compact Julia binaries for embedded systems and real-time deployment, simplifying integration across engineering workflows.

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JuliaHub @juliahub.bsky.social · 24/10/2025

Scientific Modeling Cheatsheet: SciML has published a quick reference cheatsheet translating hundreds of functions between Julia, Python and MATLAB. Click here for more. sciml.github.io/Scientific_M... #JuliaLang #SciML #Python #MATLAB #ScientificComputing #DataScience #Cheatsheet #Engineering

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Mehmet Hakan Satman @jbytecode.bsky.social · 18/10/2025

Julia v1.12.1 is out! 🎈🙃 #JuliaLang

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Diego Javier Zea @diegozea.bsky.social · 17/10/2025

🚀 MIToS.jl v3.2.0 brings cleaner substitution matrices, better MSA quality measures, easier MSA merges, and sturdier PDB handling — plus higher test coverage. 🧵

Dragon showing the Julia colors and the text: MIToS.jl v3.2

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Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social · 07/07/2025

Folddisco finds similar (dis)continuous 3D motifs in large protein structure databases. Its efficient index enables fast uncharacterized active site annotation, protein conformational state analysis and PPI interface comparison. 1/9🧶🧬 📄 www.biorxiv.org/content/10.1... 🌐 search.foldseek.com/folddisco

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Diego Javier Zea @diegozea.bsky.social · 24/06/2025

📢 Deadline Extended! The application deadline for the PhD student position has been extended to July 4th. If you haven’t applied yet, there’s still time! 👇

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Diego Javier Zea @diegozea.bsky.social · 13/06/2025

🚨 We're hiring a Bioinformatics Engineer! 🛠️ Develop #JuliaLang & Python tools to model structural and evolutionary features of IDPs 📅 Start: 1 Sept 2025 🎓 3+ years of higher education (Master’s or engineering diploma preferred) 👉 Apply now: emploi.cnrs.fr/Offres/CDD/U...

emploi.cnrs.fr

Portail Emploi CNRS - Offre d'emploi - Ingénieur bioinformaticien – Analyse computationnelle des protéines intrinsèquement désordonnées (H/F)

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Diego Javier Zea @diegozea.bsky.social · 12/06/2025

Great news! I’m hiring a PhD student in structural #Bioinformatics to work on modeling protein conformations and interactions at @i2bcparissaclay.bsky.social as part of the ANR SPPICES project! 🚀 📅 Start: 1 Sept 2025 ⏳ Deadline: 23 June 2025 👉Apply now: emploi.cnrs.fr/Offres/Docto...

emploi.cnrs.fr

Portail Emploi CNRS - Offre d'emploi - Doctorant en bioinformatique structurale et évolution des protéines (H/F)

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Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 17/04/2025

AlphaFold is amazing but gives you static structures 🧊 In a fantastic teamwork, @mcagiada.bsky.social and @emilthomasen.bsky.social developed AF2χ to generate conformational ensembles representing side-chain dynamics using AF2 💃 Code: github.com/KULL-Centre/... Colab: github.com/matteo-cagia...

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Frank Noe @franknoe.bsky.social · 29/03/2025

BioEmu is now easily accessible on Colab. Thank you @martinsteinegger.bsky.social and @jjimenezluna.bsky.social !! @msftresearch.bsky.social

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Diego Javier Zea @diegozea.bsky.social · 06/03/2025

@googlecolab.bsky.social now has native support for #JuliaLang! 🎉 No special setup is needed anymore—start coding and sharing your @julialang.org projects! 🚀

Screen capture of Google Colab showing their native version of Julia (1.10.8)

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Diego del Alamo @delalamo.xyz · 27/11/2024

Chai-1, the open source AF3 clone, is now available with an Apache 2 license github.com/chaidiscover...

Chai-1 is released under an Apache 2.0 License, which means it can be used for both academic and commerical purposes, including for drug discovery.

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Jacob S. Zelko @thecedarprince.bsky.social · 08/11/2024

Hey folks! I got a bit swamped with all the new #julialang BlueSky people and made my own mega Julia #programmer starter pack! go.bsky.app/Hv4RKzM What other starter packs would you want to see? I'm in health research, mathematics, and open source/science. 🧪🛟🩺 📊

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Maike Osborne @maosbot.bsky.social · 09/11/2024

New here? Interested in AI/ML? Check out these great starter packs! AI: go.bsky.app/SipA7it RL: go.bsky.app/3WPHcHg Women in AI: go.bsky.app/LaGDpqg NLP: go.bsky.app/SngwGeS AI and news: go.bsky.app/5sFqVNS You can also search all starter packs here: blueskydirectory.com/starter-pack...

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Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social · 17/11/2024

This is the first fully open source release of a AF3 like model. Awesome! Congratulations to the team.

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Razvan Borza @rborza.bsky.social · 17/11/2024

⚠️THREAD OF ALL SCIENCE-RELATED STARTER PACKS! ⚠️ 🔄Share to help people finding its topic/field - STRUCTURAL BIOLOGY Structural Biology 1: bsky.app/starter-pack... Structural Biology 2: bsky.app/starter-pack... Crystallography: bsky.app/starter-pack... Synchrotron&CryoEM: bsky.app/starter-pack...

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Diego Javier Zea @diegozea.bsky.social · 30/01/2024

🎉 Exciting news! Our latest paper in Nature Communications delves into protein-protein interaction networks & IDRs using AlphaFold2. Dive into our findings here! 🧬 #Bioinformatics 1/8

Robot hand placing a protein fragment into the surface of a globular protein.

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Diego del Alamo @delalamo.xyz · 26/01/2024

Gonna stop curating structbio/ML preprint & papers for a few weeks. The colab notebook below should mostly do the trick (except arxiv) for anyone interested in catching up on whats going on colab.research.google.com/drive/17e0pD...

colab.research.google.com

Google Colaboratory

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Jessica Andreani @jessicaandreani.bsky.social · 18/01/2024

Happy to share our research on using AlphaFold2 to predict how peptides from disordered regions bind proteins, just published in NatureComms rdcu.be/dwlLa Work done with Hélène Bret and Raphael Guerois and for the revised version with great contributions from @diegozea.bsky.social and Jinmei Gao. 🧬🧶

rdcu.be

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Luis Pedro Coelho @luispedrocoelho.bsky.social · 15/01/2024

New experiment: I will work on a project (starting question: what antibiotic resistance genes co-occur in genomes/metagenomes and does it matter?) completely in the open Everyone is welcome!

youtu.be

Extremely Open Science Part 1 : introduction

#science #presentationLuis Pedro Coelho introduces the Extremely Open Science Project for 2024Links:- https://www.big-data-biology.org/extremely-open-science...

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Diego del Alamo @delalamo.xyz · 03/01/2024

CASP16 will start later this year, so to celebrate that here is a short thread on the uncanny valley separating experimental structures & computational models of proteins. Even though the latter are extremely accurate, there are still some weird differences that are hard to pin down. 🧪🧶🧬🧵

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Diego del Alamo @delalamo.xyz · 31/12/2023

My wish for 2024 is that all authors are this direct with their findings

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Chris Rackauckas @chrisrackauckas.bsky.social · 25/12/2023

Joris K. - Building Fast Packages Faster: #Julialang as a Backend to #Python and #R (#RStats) Using Julia instead of C or Fortran for package internals can have many advantages for Python and R users, since the language acts more similar to the higher level languages www.youtube.com/watch?v=JD8H...

youtube.com

Joris K. - Building Fast Packages Faster: Julia as a Backend to Python and R

Using Julia instead of C or Fortran for package internals can have many advantages for Python and R users, since the language acts more similar to the higher...

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