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Diego Javier Zea

@diegozea.bsky.social

1.9K followers 4.1K following 43 posts

Associate Professor at Université Paris-Saclay. Interested in Protein Structure, Interactions and Evolution, Machine Learning, and Julia programming. diegozea.github.io

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Diego Javier Zea @diegozea.bsky.social · 19/08/2026

5/7 I also presented a poster at #JuliaCon on MIToS.jl, my Julia package for working with protein sequences and structures. AlphaConformers relies heavily on MIToS, and developing the pipeline drove several improvements on it. MIToS: github.com/diegozea/MIT...

Me with my poster presenting the new features of MIToS at JuliaCon Global 2026.

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Diego Javier Zea @diegozea.bsky.social · 19/08/2026

1/7 Two busy weeks around AlphaConformers: last week I presented it at #JuliaCon Global 2026; this week, our preprint is out on bioRxiv. The question behind it: can structural information help AlphaFold explore alternative protein conformations? 🧵

Here's the image of the apo-form, which serves as the query, alongside the holo-form, the target, along with the closest AlphaConformer model for the holo form, illustrating a successful example.

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Diego Javier Zea @diegozea.bsky.social · 17/10/2025

🚀 MIToS.jl v3.2.0 brings cleaner substitution matrices, better MSA quality measures, easier MSA merges, and sturdier PDB handling — plus higher test coverage. 🧵

Dragon showing the Julia colors and the text: MIToS.jl v3.2

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Diego Javier Zea @diegozea.bsky.social · 06/03/2025

@googlecolab.bsky.social now has native support for #JuliaLang! 🎉 No special setup is needed anymore—start coding and sharing your @julialang.org projects! 🚀

Screen capture of Google Colab showing their native version of Julia (1.10.8)

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Diego Javier Zea @diegozea.bsky.social · 30/01/2024

🎉 Exciting news! Our latest paper in Nature Communications delves into protein-protein interaction networks & IDRs using AlphaFold2. Dive into our findings here! 🧬 #Bioinformatics 1/8

Robot hand placing a protein fragment into the surface of a globular protein.

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