The thermostability of RNA vaccines is improved with AI.

How cumulative environmental allergen exposures are encoded by peripheral sensory neurons to shape immune responsiveness is unclear. Zhu et al. show that protease allergens induce an…

CD4+Foxp3+ regulatory T cells (Treg) are essential for maintaining immune tolerance in both lymphoid and non-lymphoid tissues, including transplanted organs. Understanding the mechanisms that…

Claimed Navier-Stokes solution has polarized mathematicians over AI’s role—and what it means for the next generation

1. used to express disappointment at the fact that a situation is not as you…

Amid a shortage of human reviewers, tests indicate AI can assist—but is not a savior

Within the skin, glutamatergic neurons expressing neurofilament heavy chain (Nefh) play a role in aging. Loss of Nefh during aging drives skin fibroblast senescence and collagen loss, whereas…

Nucleic acid sensing by endolysosomal Toll-like receptors is critically involved in systemic lupus erythematosus (SLE) and related autoimmune disea...

A positive trial holds promise for treating people with cancer. More research is needed to get effective vaccines to the clinic.

New ruling bars programs said to discriminate by race and sex, six others can continue if modified

Fecal microbiome transplant up-regulates immune tolerance pathways in food allergy.

Using CRISPR-based TCR editing, Chi et al. systematically compare gut TCRs recognizing dietary, microbial, and self-antigens to define the principles that govern peripheral Treg cell differentiation. ...

Using CRISPR-based TCR editing, Chi et al. systematically compare gut TCRs recognizing dietary, microbial, and self-antigens to define the principles that govern peripheral Treg cell differentiation.…

Extracellular ATP (eATP) is associated with immune suppression in the tumor microenvironment (TME) via its metabolite adenosine. Hu et al. find that immunotherapy increases eATP within the TME and…

Diet shapes obesity-associated therapeutic responses to immune checkpoint inhibitors through gut microbial metabolism and host anti-tumour immunity, demonstrated in mouse custom-diet models and…

Xue et al. describe the dynamics of chromatin architecture during exhausted CD8+ T cell fate decisions and identify Id proteins as key regulators.

Originally from Beslan, North Ossetia, singer Karina Kushtati has embraced Georgia, often performing traditional songs from across the Caucasus.