Esmaeilishirazifard et al. present a high-throughput drug screening platform that uses real-time bioluminescent monitoring to measure the viability of PDTX-derived tumor cells during drug treatment. T...

Tu et al. present a systematic analysis of the tumor microenvironment across 14,837 breast cancers, identifying distinct cellular patterns that predict disease-specific survival independently of genom...

Abstract. Germline CDH1 loss-of-function mutations are causally linked to an increased lifetime risk of diffuse gastric cancer (DGC). Early, multifocal signet ring cell (SRC) lesions are ubiquitous am...

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Whole-gene sequencing of microdissected gastric glands from individuals with and without gastric cancer reveals distinct patterns of somatic mutations and provides insights into influen...

This university crisis is a grim scrabble for numbers

The developmental Genotype-Tissue Expression (dGTEx) projects will catalogue and integrate gene expression, regulation and genetics data across 120 human donors from birth to adulthood with developmen...

Clinical research should recruit participants from LGBTQIA+ populations, and this requires specific actions and policies to create affirming and welcoming environments.

Five experts share their thoughts on key areas of focus in multidisciplinary cancer research for the upcoming years. They discuss the research approaches, tools, technologies, collaborations and way o...

This proof-of-concept phase 1 trial shows that the size of circulating tumor cell clusters (which can promote metastatic spread) can be reduced by treatment with the Na+/K+ ATPase inhibitor digoxin in...