This study described the development of an experimental model for eosinophilic gastritis (EoG). Experimental EoG recapitulates histopathological features of human disease. including foveolar elongati...

From pregnancy until lactation, eosinophils accumulate in the small intestine where they regulate goblet cell fate and enhance innate defences against enteric pathogens.

Eosinophils have traditionally been viewed as terminally differentiated type 2 effector cells involved in anti-helminth immunity and allergic inflamma…

Laboratory mice housed under specific pathogen-free conditions are the standard model in biomedical research. However, frequent germ-free rederivation and barrier housing restrict microbial exposure a...

Marteau et al. integrate colorectal cancer single-cell datasets, classify immune phenotypes, and identify myeloid gene expression programs. Characterization of neutrophils reveals pro- and antitumorigenic properties, spatial neutrophil niches, and tumor-derived reprogramming of neutrophils in the bone marrow.