iiinova — where your digital self keeps evolving

Reposted by Daniel Irimia

Erinke van Grinsven @erinkevg.bsky.social · 14/11/2025

It has been a real pleasure to dive deep into the wonderful world of the unique and peculiar shape of the neutrophil nucleus, together with Ananda and Irina in the @udalovalab.bsky.social, and I'm proud this literature review is now out in @natrevimmunol.nature.com. rdcu.be/ePKFk

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Reposted by Daniel Irimia

Long Covid Advocacy @longcovidadvoc.com · 17/11/2025

Researchers compared blood from Long Covid patients with healthy controls, focusing on two features: microclots and NETs (neutrophil extracellular traps). 2/ www.independent.co.uk/news/science...

independent.co.uk

Long Covid has done something strange to people’s blood

Tiny clots appeared larger-than-normal in long Covid patients, study finds

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Journal of Cell Biology @jcb.org · 19/11/2025

Wang, Kim, Ding et al. of the Qing Deng lab demonstrate that inward-rectifying potassium channels maintain the resting membrane potential and are required for directional sensing during #neutrophil chemotaxis. rupress.org/jcb/article/...

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Journal of Cell Biology @jcb.org · 26/11/2025

Inwardly rectifying potassium channels promote directional sensing during #neutrophil chemotaxis, say Tianqi Wang, Daniel Kim, Chang Ding, GuangJun Zhang, Qing Deng, and colleagues (Purdue University) rupress.org/jcb/article/... #Migration #motility #Immunology

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ME/CFS Science @mecfsscience.org · 21/10/2025

1) Dr. Vanessa Velasco gave preliminary results on OMF's new neutrophil study. She found that neutrophils of ME/CFS patients died quicker and more often than those of healthy controls, under inflammatory conditions.

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Daniel Irimia @daniel-irimia.bsky.social · 29/10/2025

Qualitative and Quantitative Analysis of Circulating NET-derived chromatin and nucleosomes in... - goo.gl/scholar/MJk5Y4 #ScholarAlerts

goo.gl

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Reposted by Daniel Irimia

NEJM.org @nejm.org · 18/10/2025

A 52-year-old man with a history of splenectomy and hypogammaglobulinemia after CAR T-cell therapy for lymphoma 3 years earlier was admitted with septic shock. Encapsulated diplococci were seen in 20% of neutrophils. Read the full case details: nej.md/4oap9GL #MedSky #IDSky

Images in Clinical Medicine
Pneumococcal Sepsis in a Patient with Asplenia and Hypogammaglobulinemia

Panel A: Encapsulated diplococci seen in 20% of neutrophils on a peripheral-blood smear.
Panels B and C: Multiorgan dysfunction and purpura fulminans of the nose and fingers developed.

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Reposted by Daniel Irimia

Nader Ghasemlou @ghasemloulab.bsky.social · 02/10/2025

We've published our very first clinical study where we found that chronic low back pain rhythmicity contributes to biopsychosocial outcomes, including opioid use, via the neutrophil degranulation pathway t.co/0yFdJemScW

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Journal of Clinical Investigation @jci.org · 01/10/2025

This issue’s cover art represents the potential for improving pain relief by restoring circadian rhythmicity @ghasemloulab.bsky.social & team link daily pain rhythmicity with neutrophil activation, better biopsychosocial profiles, & reduced opioid use: buff.ly/GR3SOAK

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Blood Journals Portfolio @bloodjournals.hematology.org · 02/10/2025

New Blood issue out featuring: The acute myeloid leukemia microenvironment impairs neutrophil maturation and function through NF-κB signaling buff.ly/0vhlcDl

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NEJM.org @nejm.org · 04/07/2025

𝐏𝐡𝐚𝐠𝐨𝐜𝐲𝐭𝐨𝐬𝐢𝐬 is the process by which a phagocyte (a type of white cell such as macrophage, monocyte, or neutrophil) engulfs large particles, usually pathogens or debris from dead or dying cells, and removes them from the bloodstream. #MedSky #ScienceSky

A visual representation of "phagocytosis"

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Amber Stratman @astratman.bsky.social · 15/07/2025

Excited to be involved with this work driven by @dremilygoldberg.bsky.social and her team! Read the preprint now! "Neutrophil TLR2 signaling promotes lipid accumulation and vascular plaque growth"

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NEJM.org @nejm.org · 04/07/2025

To learn more about this NEJM Illustrated Glossary term, read the editorial “Defanging the Neutrophil to Treat Bronchiectasis” by Adam T. Hill, MD: nej.md/4cANv89  Explore more terms: nej.md/glossary

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Reposted by Daniel Irimia

Alejandro Brenes @ajbrenes.com · 27/07/2025

This is a technical feat showing the progress in sample processing an instrument sensitivity, as we estimate we inject 30pg of protein content from a single neutrophil. Yet we can detect >3,000 proteins from 500 neutrophils and >1,100 from a single GBM associated neutrophil!

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Daniel Irimia @daniel-irimia.bsky.social · 13/08/2025

A new drug acting on neutrophils is FDA cleared - an event in that not many neutrophil-acting drugs are out there! This is an inhibitor of DPP1... read more insmed.com

insmed.com

Insmed | For us, everything starts with people.

We work hard to understand the experiences of those living with serious diseases as we strive to deliver true change.

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