This population-based cohort study assesses the association between prenatal paracetamol exposure and risk of autism spectrum or attention-deficit/hyperactivity disorder using a sibling-matched design.

This randomized clinical trial investigates whether a telehealth-delivered mindfulness group medical visit program for persons with chronic low back pain improves pain intensity and interference compared with usual care.

This qualitative study explores the perspectives of primary care physicians regarding their own well-being and the health and well-being of their immigrant patients after anti-immigrant policy changes in January 2025.

There is a growing literature on physician sex differences in patient care and outcomes that largely favor female physicians. Studies in the primary care setting find, for example, that female physicians spend more time in direct and indirect patient care,1 use more patient-centered communication,...

Randomized clinical trials, when rigorously conducted, offer the highest level of evidence to evaluate health care interventions. The value of a health care intervention depends on the benefits relative to the harms, which can be physical, psychological, or social.1,2 Published reports of randomized...

The National Institutes of Health (NIH) has a strong interest in ensuring that the knowledge arising from research it funds is available to the scientific community and the general public. A key contr...

Kenneth Covinsky, MD, MPH, Krista Harrison, PhD, Lauren Hunt, PhD, RN, FNP, and colleagues have published a new study in JAMA examining rural-urban disparities in hospice care.

This randomized clinical trial evaluates the effect of routine referral of patients with prostate cancer to a cardiovascular specialist for systematic risk factor control compared with usual care.

This Clinical Insights summarizes current cervical cancer screening recommendations.

This cohort study investigates the association of alpha-gal syndrome prevalence among patients with blood type O blood and rates of allergic transfusion reaction.

At JAMA Internal Medicine, we have become increasingly aware that some US researchers are unable to report on race or ethnicity as demographic variables to describe their sample or to conduct stratified analyses by these variables. In some cases, we have been informed that based on 3 recent US...

The National Institutes of Health (NIH) has a strong interest in ensuring that the knowledge arising from research it funds is available to the scientific community and the general public. A key contributor to the Open Science movement, the NIH has embraced a variety of strategies, including...