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Carolina Sanchez-Rocha

@caro-rocha.bsky.social
57 followers 50 following 6 posts

Postdoc at @Weizmann Institute in Naama Barkai's lab 🧪🧬 | Structural biologist | Evolutionary biologist 🌳🪸🦠 | Art lover 🎨

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Reposted by Carolina Sanchez-Rocha
Hassan uz Zaman @hassanzaman.bsky.social · 09/03/2026
This talk is happening tomorrow—as part of the Protein Structure Evolution seminar! Click here to register if you like cool science: tinyurl.com/prose-seminar2 Organized by @lacholt.bsky.social, @caro-rocha.bsky.social, @claudiaalcar.bsky.social, @zachary-ardern.bsky.social and myself.
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Reposted by Carolina Sanchez-Rocha
Protein Structure Evolution (ProSE) Seminar @proteinstructure.bsky.social · 28/10/2025
The next ProSE Seminar will be given by Joana Pereira @joanampereira.bsky.social (VIB, KU Leuven) 🗓️ November 11th, 5pm CET Registration is now open: tinyurl.com/prose-seminar2 Please share!
Protein Structure Evolution Seminar
November 11, 5pm CET
Title: AI-Powered Classification and Discovery Across the Protein Universe
Speaker: Joana Pereira
Organized by: Claudia Alvarez Carreno, Zachary Ardern, Lars Eicholt, Carolina Sanchez-Rocha, Sergio Romero-Romero and MD. Hassan Uz-Zaman
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Reposted by Carolina Sanchez-Rocha
Claudia Alvarez Carreño @claudiaalcar.bsky.social · 06/10/2025
The next Protein Structure Evolution Seminar will be given by Stephen Fried (JHU): Title: “Who Cares About Protein Refolding Anyway?: Why Some Microbes Do and Others Don’t” Date: October 14th, 5 pm CET Registration link: tinyurl.com/prose-seminar2
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Reposted by Carolina Sanchez-Rocha
Claudia Alvarez Carreño @claudiaalcar.bsky.social · 15/09/2025
Happy to share Piecing Together the History of Protein Folds From a Fragmented Evolutionary Record 🧪 It appears as part of a Special Section in @genomebiolevol.bsky.social organized by @cpuentelelievre.bsky.social @proteinmechanic.bsky.social and J. Douglas doi.org/10.1093/gbe/...
doi.org
Piecing Together the History of Protein Folds From a Fragmented Evolutionary Record
Abstract. Protein folds are structural units defined by the number, type, arrangement, and orientation of their core secondary structural elements. The uni
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Reposted by Carolina Sanchez-Rocha
Claudèle Lemay-St-Denis @claudele.bsky.social · 08/10/2025
How does catalysis emerge from non-catalytic domains? In our new paper, we show that catalytic activity can arise without conserved active-site residues — through multimerization and electrostatic features instead. A striking case of catalysis evolving from binding.
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Carolina Sanchez-Rocha @caro-rocha.bsky.social · 07/09/2025
🌍ProSE Online Talk 📅 Tue Sep 9 | 🕔 5pm CET How does protein sequence → structure → function really work? Prof. Nir Ben-Tal will show how AI (CLSS) is reshaping our view of the protein universe and uncovering hidden evolutionary design. 🚀 Don’t miss this! Registration: tinyurl.com/prose-seminar2
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Reposted by Carolina Sanchez-Rocha
Claudia Alvarez Carreño @claudiaalcar.bsky.social · 02/09/2025
The ProSE seminars are back after a summer break. The next speaker is Nir Ben-Tal on "Contrastive learning unites sequence and structure in a global representation of protein space". Date: September 9 Time: 5pm CET Register here: tinyurl.com/prose-seminar2 Please share! 🧪 #mevosky
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Reposted by Carolina Sanchez-Rocha
Claudia Alvarez Carreño @claudiaalcar.bsky.social · 29/05/2025
Join us for the next ProSE Seminar! We are excited to welcome Sophie Heiding for a talk on "Computational Insights into Protein Adaptation Across Environmental Gradients" Date: June 10 Time: 4PM CET Register here: tinyurl.com/prose-seminar2 Please share! 🧪 #MEvoSky
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Reposted by Carolina Sanchez-Rocha
Claudia Alvarez Carreño @claudiaalcar.bsky.social · 01/05/2025
We are pleased to announce that the next speaker in the ProSE seminar series will be Dr. Klara Hlouchova with a talk on "Protein Structure Before LUCA" May 13, 4PM CET Registration link: tinyurl.com/prose-seminar4 Please share!
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Carolina Sanchez-Rocha @caro-rocha.bsky.social · 25/02/2025
🚨 Unravel BILLIONS of years of protein evolution! 🚨 How did protein structures emerge and evolve over deep time? Join @zachary-ardern in the next ProSE Seminar! 📅 March 11, 3PM GMT 🔗 tinyurl.com/prose-seminar2 #ProteinEvolution #StructuralBiology
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Carolina Sanchez-Rocha @caro-rocha.bsky.social · 18/02/2025
🧬 New research reveals that encoded & non-genetic protein variants shape the human proteome in ways previously unknown! These **alternative proteoforms** expand protein function bypassing genetic constraints. 🔗 Check it!: www.biorxiv.org/content/10.1... #Proteomics #CentralDogma #Translation
biorxiv.org
Encoded and non-genetic alternative protein variants expand human functional proteome
Each stage of the Central Dogma contributes to proteome diversity through mechanisms such as heterozygosity, somatic mutations, transcriptional errors, and translational errors. As a result, a diverse...
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Reposted by Carolina Sanchez-Rocha
Claudia Alvarez Carreño @claudiaalcar.bsky.social · 24/01/2025
The ProSE seminar series is organized by @zachary-ardern.bsky.social, @lacholt.bsky.social, @caro-rocha.bsky.social a.bsky.social, @hassanzaman.bsky.social and me
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Reposted by Carolina Sanchez-Rocha
Zachary Ardern @zachary-ardern.bsky.social · 24/01/2025
The ProSE seminar series is organised by @claudiaalcar.bsky.social @hassanzaman.bsky.social @lacholt.bsky.social @caro-rocha.bsky.social & me - do reach out with any questions or suggestions!
a.bsky.social
Bluesky
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Carolina Sanchez-Rocha @caro-rocha.bsky.social · 03/02/2025
New seminar series! Join us to explore how protein structures evolved! Kicking off with the outstanding work of Andrei Lupas, who revealed how ancient peptides gave rise to modern protein folds ⚗️💫 ProSE launches one day before Darwin's day! 📅 Feb 11, 3PM GMT 🔗https://tinyurl.com/prose-seminar1
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Reposted by Carolina Sanchez-Rocha
Claudia Alvarez Carreño @claudiaalcar.bsky.social · 29/01/2025
Join the ProSE Seminar Series! A monthly discussion on the #Evolution of #ProteinStructure 🧪 Next up: Andrei Lupas “Highly repetitive genomic ORFs: a source of new fibrous proteins?” 11th February | 3 PM GMT 🔗 Register here: tinyurl.com/prose-seminar1
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Reposted by Carolina Sanchez-Rocha
Lars Eicholt @lacholt.bsky.social · 31/01/2025
Co-organized by Md. Hassan Uz-Zaman, @zachary-ardern.bsky.social , @claudiaalcar.bsky.social , @caro-rocha.bsky.social & me.
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