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Christoph Gunkel

@christophgunkel.bsky.social
35 followers 79 following 5 posts

Microbial Biotech | Doctoral student @ TUM Campus Straubing

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Reposted by Christoph Gunkel
Science Magazine @science.org · 25/04/2026
In a new study, researchers describe a bacterial enzyme that synthesizes DNA without a nucleic acid template, using its own structure as a guide. Learn more on #DNADay: scim.ag/3OEc2RV
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Christoph Gunkel @christophgunkel.bsky.social · 30/04/2026
We wrote down some thoughts about microbial succinic acid production in our latest paper published in @microbiotech.bsky.social Check out the paper here: doi.org/10.1111/1751...
doi.org
Perspectives for Advancing Biotechnological Succinic Acid Production
Succinic acid is an important molecule for sustainable chemical manufacturing, but its industrial production faces high costs and sustainability challenges, which are linked to feedstocks and excessi...
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Reposted by Christoph Gunkel
bioRxivpreprint @biorxivpreprint.bsky.social · 13/02/2026
Outpacing E. coli: Development of Vibrio natriegens as a Next-Generation Cloning Host www.biorxiv.org/content/10.64898/20…
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Reposted by Christoph Gunkel
CCI Uni of Liverpool @cci-liv.bsky.social · 13/10/2025
🚨📣 Pathogenic bacteria assemble protein-based microcompartments to digest ethanolamine in the gut, a process essential for their growth and survival and a potential target for antimicrobial strategies. doi.org/g95j7q Synergy of multiple UoL Shared Research Facilities also 🚨📣 @makaefer.bsky.social
doi.org
Molecular basis of the biogenesis of a protein organelle for ethanolamine utilization
EutQ governs enzymatic cargo encapsulation within the protein shell to drive Eut microcompartment biogenesis in Salmonella.
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Reposted by Christoph Gunkel
Science X / Phys.org @sciencex.bsky.social · 12/08/2025
Engineered yeast now produces succinic acid from plant sugars with an 85% yield, significantly lowering production costs and advancing sustainable alternatives to petrochemical-based methods. doi.org/g9wn2w
phys.org
Ready for market: Engineered yeast boosts clean, cost-efficient chemical production
Building on their success developing a cleaner way to make valuable organic acids, researchers from the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) have pushed one product closer to commercialization with a major upgrade in yield.
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Reposted by Christoph Gunkel
C&EN (Chemical & Engineering News) @cenmag.bsky.social · 07/10/2025
Researchers have invented a system that captures carbon dioxide from ocean water and converts it to succinic acid, a key monomer used to make the commonly used biodegradable plastic polybutylene succinate. cen.acs.org/environment/... #chemsky 🧪
cen.acs.org
Turning ocean carbon into biodegradable plastic
System is first to pull carbon dioxide from the ocean and convert it to valuable product
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Christoph Gunkel @christophgunkel.bsky.social · 03/09/2025
Advances in metabolic engineering of Vibrio natriegens as an unconventional host for biotechnology doi.org/10.1016/j.ym...
doi.org
Redirecting
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Reposted by Christoph Gunkel
Microbial Biotechnology (MBT) @microbiotech.bsky.social · 11/06/2025
#MicroSky: SynBIOL: Engineered E. coli makes creatine! By adding AGAT & GAMT plus an ATP regeneration system, Shen et al achieve >5 g/L CR with high productivity. A new platform for ATP-hungry metabolite production! doi.org/10.1111/1751...
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Reposted by Christoph Gunkel
PLOS Biology @plosbiology.org · 22/04/2025
The unique #CellEnvelope of #corynebacteria: @tbharat-lab.bsky.social &co map the C. glutamicum cell surface, revealing a patchy S-layer & specific assembly of the PS2 protein, thereby informing our understanding of cell envelopes that contain #MycolicAcids @plosbiology.org 🧪 plos.io/3Y6JNgw
Left: The atomic model of the PS2 lattice is shown in top and side views. PS2 hexamers are repeated in the 2D sheet with a lattice constant of 176 Å. Each PS2 monomer is colored and labeled separately within the hexamer, which repeats throughout the lattice (with pore dimensions highlighted). The side view of the lattice shows the smooth surface facing the extracellular space and rough surface with coiled-coil segments protruding towards the MM. Top right: Interactions at the hexameric and trimeric interfaces are stabilized by both hydrophilic and hydrophobic residues. Bottom right: A cell envelope tomogram was used to overlay the cryo-EM structure of the S-layer onto the in situ S-layer tomographic density. A single slice of the tomogram is shown, with the overlayed PS2 S-layer lattice in green and the tomogram in grayscale. The S-layer (surface layer), MM (mycomembrane), IM (inner membrane), and Cytosol are labeled.
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Reposted by Christoph Gunkel
Alf Soler-Bistué 🦠🔬🧫 @alfmicrobe.bsky.social · 10/04/2025
I was waiting two years to see this out!! The genomic location of bacterial genes is not random!!! Congratulation on the authors (Martin Lercher and Team!). www.science.org/doi/10.1126/...
science.org
Most bacterial gene families are biased toward specific chromosomal positions
The arrangement of genes along bacterial chromosomes influences their expression through growth rate–dependent gene copy number changes during DNA replication. Although translation- and transcription-...
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Reposted by Christoph Gunkel
VAAM e.V. @vaam-microbes.bsky.social · 17/02/2025
BIOspektrum issue 1/25 is on its way to your📫 This edition features the latest news from across the biosciences along with our special coverage on the Microbe of the Year 2025 #MdJ Corynebacterium glutamicum🦠🧪🏆 t1p.de/egenx
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