AbstractAims. In the heart, endogenous nicotinic acid adenine dinucleotide phosphate (NAADP) triggers lysosomal calcium (Ca2+) release to augment sarcoplas

BEHAV3D is a 3D live imaging platform for analyzing engineered T cell behavior and tumor response. This provides insights into the mode of action of cellular immunotherapy, capturing heterogeneity wit...

Cysteine is a central metabolite in cellular redox regulation and iron-sulfur cluster assembly. Despite its critical role, monitoring cysteine dynamics in living systems has remained a challenge due t...

NanoPyx optimizes bioimage analysis workflows by dynamically selecting code variations based on input data and hardware. This ensures maximum computational efficiency, enabling fast analysis of large ...

The people who work behind the scenes to keep research moving say that there should be more recognition for their roles.

YouTube video by Biochemistry Focus webinar series

Spurred by a recent report on sexual harassment in academia, our columnist revisits a historical case and reflects on what has changed—and what hasn’t

EutQ governs enzymatic cargo encapsulation within the protein shell to drive Eut microcompartment biogenesis in Salmonella.

The function and position of organelles are pivotal for tumor cell dissemination. Here the authors use melanoma patient samples and animal models to show that peripheral localization of lysosomes prom...

AI and tissue clearing-based technologies for health. Director at Helmholtz Munich, Full professor at LMU Munich, and CEO of Deep Piction (@deeppiction.bsky.social) We’re🇩🇪🇹🇷🇭🇷🇨🇳🇮🇹🇮🇳🇸🇮🇴🇲🇨🇱🇭🇺🇧🇬🇺🇦🇷🇴🇦🇹🇹...