Author summary The human cerebral cortex is thought to encode sensory information in population activity patterns, but the statistical structure of these population codes has yet to be characterized. ...

The reinforcement learning community has made significant progress in understanding dopamine (DA) in reward learning, cognitive control, and motivatio…

In EEG and fMRI analysis, researchers choose from a combinatorially large set of theoretically indistinguishable options while building a data processing pipeline based on individual beliefs and other...

Aperiodic neural activity - activity with no characteristic frequency - has increasingly become a common feature of study, including in clinical work. Reports investigating aperiodic activity from pat...

Nature Communications - People often discard incoming information when it contradicts their pre-existing beliefs about the world. Here, the authors show that this discarded information is precisely...

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It has been widely believed that a key function of sleep is to actively clear metabolites and toxins from the brain. Miao, Luo et al. show in mice that brain clearance is markedly reduced—not increase...

While neurological and psychiatric disorders have historically been considered to reflect distinct pathogenic entities, recent findings suggest shared pathobiological mechanisms. However, the extent t...

This case-control study investigates whether the incidence of dementia in the general population covaries with long-term exposure to microlevels of lithium in drinking water.

Background Dementia is associated with psychiatric symptoms but the effects of antidepressants on cognitive function in dementia are understudied. We aimed to investigate the association between antid...