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Cenk Celik

@cenkcelik.bsky.social
49 followers 69 following 20 posts

Research Fellow @ugiatucl.bsky.social • Single-cell and spatial transcriptomics • EACR Ambassador cenk-celik.github.io

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Reposted by Cenk Celik
UCL Faculty of Life Sciences @ucllifesciences.bsky.social · 16/09/2026
Could targeting CD1d make immunotherapy more effective? New research from @ucllifesciences.bsky.social , @kingscollegelondon.bsky.social and the @crick.ac.uk points to a promising new approach for breast cancer treatment. 🔗 www.ucl.ac.uk/life-science...
ucl.ac.uk
Researchers identify potential target to boost anti-cancer immunity in breast cancer
Researchers have identified a potential target to make the environment surrounding breast tumours more favourable to anti-cancer immune responses.
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Reposted by Cenk Celik
Journal of Experimental Medicine @jem.org · 09/09/2026
CD1d remodels the tumor-infiltrating myeloid populations controlling anti-tumor immunity. From Lauren Evans, Maria Conde Poole, Patricia Barral @barrallab.bsky.social: rupress.org/jem/article/... Part of our #CancerImmunotherapy 2026 👉 rupress.org/jem/collecti... #CSHAsia
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Journal of Experimental Medicine @jem.org · 13/08/2026
Evans et al. @barrallab.bsky.social identify CD1d as a key regulator of myeloid cell diversity in #BreastCancer. CD1d targeting reshapes tumor immune infiltrates, suppresses tumor growth, & enhances #immunotherapy efficacy, suggesting an actionable pathway for treatment. rupress.org/jem/article/...
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Alexis Barr @alexisbarr.bsky.social · 30/07/2026
Through a fantastic collaboration with @mariasecrier.bsky.social we show how dormant breast cancer cells occupy protected niches, presenting a therapeutic challenge. Congratulations to @cenkcelik.bsky.social for a super study
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Bilimler Köyü @bilimler.bsky.social · 30/07/2026
Yapay zeka teknolojilerinin toplumsal yaşamın her alanında yarattığı dönüşümler, ona bütüncül bir perspektifle yaklaşmayı zorunlu kılıyor. Bu etkinlik böyle bir perspektifi kurmanın yollarını aramak üzere tasarlandı. Kayıtlar devam ediyor: bilimler.org #bilimlerköyü #villageofsciences #yapayzeka
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UCL Faculty of Life Sciences @ucllifesciences.bsky.social · 20/07/2026
Congratulations to UCL’s Dr Gemma Murray on receiving a prestigious Wellcome Career Development Award, recognising her pioneering research into bacterial evolution and antimicrobial resistance. @ugiatucl.bsky.social www.ucl.ac.uk/life-science...
ucl.ac.uk
Gemma Murray awarded prestigious Wellcome Career Development Award
Dr Gemma Murray has been awarded a Wellcome Career Development Award to lead pioneering research into the hidden role of commensal bacteria in antimicrobial resistance (AMR).
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Reposted by Cenk Celik
Alastair Lamb @lambalastair.bsky.social · 15/07/2026
Real treat to have @cenkcelik.bsky.social from @mariasecrier.bsky.social give #CEV talk "2 systems:1 Biology". Transferable concepts from #WoundHealing➡️ #CancerTransformation @qmbci.bsky.social @mcclellandlab.bsky.social @ciccarellilab.bsky.social @mirjana-efremova.bsky.social @mlockley.bsky.social
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Cenk Celik @cenkcelik.bsky.social · 12/06/2026
Are you interested in learning multiomics analysis for your project? Join me for a hands-on workshop at Bilimler Köyü (Village of Sciences) in Foça, İzmir for a week. #spatialtranscriptomics #scrnaseq
Life at the single-cell and spatial resolution.
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Biochemical Society @biochemsoc.bsky.social · 02/06/2026
G0 or no-G0, if you’re interested in learning the role of phosphatases in regulating quiescence and cell cycle entry read this new review by Robinson & Barr published in #BiochemSocTrans doi.org/10.1042/BST20250091 🧪
Overview of phosphatases controlling G0 entry, maintenance, and exit towards G1/S
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Bilimler Köyü @bilimler.bsky.social · 02/05/2026
10–16 Ağustos’ta Cenk Çelik hocamızın yürütücülüğünde gerçekleşecek olan bu etkinlikte; biyolojide tek hücreden uzamsal ölçeklerdeki yaşamın derinliklerine uzanan bir hattı, bilimsel verilerle iç içe tartışıyoruz. Merkezi dogma ve veri işlemeden gen düzenleyici ağlara; hücreler+
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Kimberly Kline 🏔 @kimingeneva.bsky.social · 27/01/2026
Lactic acid lover? Check out @ronni.bsky.social 's new work in @cp-cellhostmicrobe.bsky.social showing how Enterococcus faecalis-derived LA suppresses macrophage activation, in turn promoting bacterial persistence and polymicrobial wound infection in vivo. www.sciencedirect.com/science/arti...
sciencedirect.com
Enterococcus faecalis-derived lactic acid suppresses macrophage activation to facilitate persistent and polymicrobial wound infections
Macrophage activation is essential for innate immunity and antimicrobial defense. We show that Enterococcus faecalis suppresses macrophage activation …
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Alexis Barr @alexisbarr.bsky.social · 23/01/2026
We are also recruiting a Postdoc in cell/molecular biology! 3yr, fully funded by @cancerresearchuk.org more details here: news.cancerresearchuk.org/2025/11/27/s... Apply here: www.imperial.ac.uk/jobs/search-...
news.cancerresearchuk.org
Spin doctors: taking on the challenge of tissue-specific cell cycle control - Cancer Research UK - Cancer News
A false start, a Nobel Prize and renewed hope – understanding cell cycle disruption over different tissues is complex. But we are getting there…
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UCL Genetics Institute @ugiatucl.bsky.social · 22/01/2026
See UGI's Dr Marina Escalera Zamudio (Rosetrees Fellow) and Dr Cenk Celik (Research Fellow) @cenkcelik.bsky.social presenting at the Norwich Science Festival @niscifest.bsky.social session on "Reimagining Health with Big Data". norwichsciencefestival.co.uk/whats-on/rei... #NISF26
norwichsciencefestival.co.uk
Reimagining Health with Big Data | Norwich Science Festival
Dr Marina Escalera Zamudio and Dr Cenk Celik will share the ways in which big data and AI are transforming medicine.
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Guillaume Thibault @gthibault.bsky.social · 17/01/2026
Proud of this international effort led by NTU Singapore, @scelse.bsky.social and the University of Geneva. Huge props to first author @aarontan.bsky.social and my co-lead @kimingeneva.bsky.social and other authors including @cenkcelik.bsky.social. #ScienceAdvances #Microbiology #NTUsg
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Marie Monniaux @mariemonniaux.bsky.social · 13/01/2026
Have you ever heard that women have more chances than men of getting grants or positions in academia? Of course you have, and here are my personal views on this. With the shocking revelation that no, it is NOT TRUE ! (1/n)
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Lucy van Dorp @lucyvandorp.bsky.social · 08/01/2026
There's still a few days left to apply for our AI-Intervene PhD project mapping the drivers of avian influenza using viral genomics, bird migration data and AI-powered phylodynamics. Come join us! Details below. #FindaPhD #LondonPhD #genomics
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UCL Genetics Institute @ugiatucl.bsky.social · 09/12/2025
Great talk from @ugiatucl.bsky.social post-doc @cenkcelik.bsky.social presenting his work developing new approaches to explore the spatial patterns of cancer evolution. Preprint 👉 www.biorxiv.org/content/10.1... Thanks for giving our last seminar of the year!
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iMadeIt Apps @imadeitapps.bsky.social · 03/12/2025
We’re live! iMeanIt – Highlight Words. Forever. ✨ Highlight. Note. Remember. All while browsing. 1️⃣ Highlight anything on a webpage. Your highlights stay—refresh or revisit, they’re still there. 2️⃣ Add notes instantly. Tap a word → view or edit annotations in seconds.
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Maria Secrier @mariasecrier.bsky.social · 07/10/2025
How do tissues organise, adapt, or collapse? 🧬 We’re looking for a postdoc with strong quantitative skills to tackle these questions in a highly interdisciplinary project bridging spatial omics, ecology & mathematical modelling (expertise required in at least one topic). Apply 👉 tinyurl.com/3d37d3st
ucl.ac.uk
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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Maria Secrier @mariasecrier.bsky.social · 19/09/2025
Come do some cool cell cycle science with the awesome @alexisbarr.bsky.social and me! 🔬✨ We’re looking for an enthusiastic computational biologist / data scientist (4-year postdoc) to dive into loads of cancer genomics & transcriptomics data. Details below. Please share!
imperial.ac.uk
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
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Alexis Barr @alexisbarr.bsky.social · 18/09/2025
@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer. Deadline 15th October. Get in touch if you have any questions. Please repost! More details: www.imperial.ac.uk/jobs/search-...
imperial.ac.uk
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
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Alexis Barr @alexisbarr.bsky.social · 03/09/2025
Feeling very fortunate to be awarded a Programme Foundation Award from CRUK @cruk-si.bsky.social This is a new area for the lab & lets us team up with @mariasecrier.bsky.social to tackle a big problem of how different cancers lose control of proliferation
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Bilimler Köyü @bilimler.bsky.social · 14/08/2025
Bu hafta “Yapay Zekanın Politik Ekonomisi” etkinliğinde Altuğ Yalçıntaş hocamız “büyük veri” meselesini iktisadi ve siyasal boyutlarıyla ele alırken, aynı saatlerde Cenk Çelik hocamız Tek Hücre ve Uzamsal Boyutta Canlılık” atölyesinde “hücreler arası iletişim konusunu masaya yatırıyordu.
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Maria Secrier @mariasecrier.bsky.social · 12/08/2025
We recently published a review reflecting on challenges and opportunities in characterising cancer cell states and niches using spatial transcriptomics and integration with digital pathology, see full thread below. Thank you Molecular Oncology for the opportunity!
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Guillaume Thibault @gthibault.bsky.social · 11/08/2025
📢 Our new preprint is out! We show how the common gut bacterium 𝘌. 𝘧𝘢𝘦𝘤𝘢𝘭𝘪𝘴 stops wound healing. It uses a metabolic pathway, extracellular electron transport (EET), to stress host cells, halting their migration. Watch WT bacteria (orange) stop the cells while the mutant (blue) doesn't!
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Bilimler Köyü @bilimler.bsky.social · 04/08/2025
Bilimler Köyü'nde gelecek hafta... 📍 Detaylı bilgi ve başvuru: bilimler.org/etkinlikler/ #bilimlerköyü #villageofsciences
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Cenk Celik @cenkcelik.bsky.social · 26/07/2025
We, Secrier Lab UCL @ugiatucl.bsky.social Genetics Institute, discussed challenges in cell state identification using spatial transcriptomics in cancer research, now out in Molecular Oncology. 
doi.org/10.1002/1878...
#SpatialTranscriptomics #CancerResearch #SpatialNiches
doi.org
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UCL Genetics Institute @ugiatucl.bsky.social · 03/06/2025
New preprint from the Secrier lab. @cenkcelik.bsky.social @mariasecrier.bsky.social present EnrichMap, a Python package to compute gene set enrichment scores in spatial transcriptomics data: tinyurl.com/yc48f4fx. See an explainer thread from @cenkcelik.bsky.social here: bsky.app/profile/cenk....
biorxiv.org
EnrichMap: Spatially informed enrichment analysis for functional interpretation of spatial transcriptomics
Advances in spatial transcriptomics (ST) allow high-resolution mapping of gene expression within intact tissues, revealing spatially regulated biology. However, accurately quantifying gene set activit...
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Maria Secrier @mariasecrier.bsky.social · 02/06/2025
Want to uncover biologically meaningful patterns in spatial omics data? Check out our new method EnrichMap, details below. Work led by the brilliant @cenkcelik.bsky.social! #spatialomics #genesets
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Cenk Celik @cenkcelik.bsky.social · 02/06/2025
[Preprint alert] We’re thrilled to introduce EnrichMap: a powerful new method for spatial gene set enrichment. It’s spatially aware, biologically meaningful and built for the next generation of spatial transcriptomics. www.biorxiv.org/content/10.1...
Description of a computational method for computing biological signals in spatial transcriptomics.
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Bilimler Köyü @bilimler.bsky.social · 24/05/2025
bsky.app/profile/bili...
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Bilimler Köyü @bilimler.bsky.social · 15/05/2025
Işık yalnızca çevremizi aydınlatmaz; aynı zamanda doğanın en temel sırlarını da içinde taşır. Bu etkinlikte, Cambridge Üniversitesi’nden Prof. Mete Atatüre ve Dr. Yusuf Karlı’nın yürütücülüğünde, ışığın klasik fiziğin ötesine geçen dünyasına adım atacağız. ++
"Işığın Derinliklerine Yolculuk" başlıklı afişte, Cambridge Üniversitesi'nden Mete Atatüre ve Yusuf Karlı'nın fotoğrafları yer alıyor. Etkinlik tarihi: 14–20 Temmuz 2025. Arka planda ışık huzmeleriyle süslenmiş bir uzay-temalı görsel bulunuyor. Afişin altında "Bilimler Köyü" ve www.bilimler.org adresi yazıyor.
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Bilimler Köyü @bilimler.bsky.social · 09/04/2025
Yaşamı tek bir hücrenin sınırlarından başlayarak uzamsal boyutlara taşıyoruz. Bu etknlikte, hücresel düzeyde bilginin nasıl aktarıldığını, düzenlendiğini ve farklı mekânsal ölçeklerde nasıl organize olduğunu birlikte inceleyeceğiz.++
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Kimberly Kline 🏔 @kimingeneva.bsky.social · 01/02/2025
Check out how 💪🏼Enterococci💪🏼 use lactic acid to suppress the inflammatory response and promote virulence. Project started by Brenda Tien during her PhD and brought home by the always excellent @ronni.bsky.social! 🥳
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bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 13/01/2025
Balancing tumour proliferation and sustained cell cycle arrest through proteostasis remodelling drives immune niche compartmentalisation in breast cancer www.biorxiv.org/content/10.1101/202…
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Maria Secrier @mariasecrier.bsky.social · 02/01/2025
New insights into the role of p21 in lung cancer from the fantastic @alexisbarr.bsky.social!
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Fabian Theis @fabiantheis.bsky.social · 12/12/2024
1/🚀 Excited to share RegVelo, our new cell model combining RNA velocity with gene regulatory network (GRN) dynamics to model cellular changes and predict in silico perturbations. Here's how it works and why it matters! 🧵👇 biorxiv.org/content/10.1101/2024.12.11.627935v1
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