Pages of the Rudolph laboratory at Brunel University London.

imageimageKRAS mutations at codon 12 induce profound metabolic changes in colorectal cancer cells. These oncogenic mutations promote FOXO1-dependent glutamine and nitrogen recycling, uncovering a vuln...

CenGEM | Centre for Genome Engineering and Maintenance · Episode

London, UK – May 13, 2025 – Axovia Therapeutics Ltd., a biotechnology company developing therapies to address the genetic causes of blindness and obesity, announced the presentation of new preclinical...

Quantitative Biology: Papers and Perspectives · Episode

ABSTRACT. Barbara Tanos is a Senior Lecturer in Biomedical Sciences in the Department of Life Sciences at Brunel University London (UK). Barbara received her undergraduate degree from the University o...

3D bioprinting techniques enable the precise deposition of living cells, biomaterials, and biomolecules, emerging as a promising approach for engineering functi

Scientists have developed an automated tool to study cell growth and division, including hard-to-study, free-floating blood cancer cells.

Methods that identify protein-protein interactions are essential for understanding molecular mechanisms controlling biological systems. Proximity-dependent labeling has proven to be a valuable method for revealing protein-protein interaction networks in living cells....

Abstract. GENCODE produces comprehensive reference gene annotation for human and mouse. Entering its twentieth year, the project remains highly active as n

Breast Cancer Risk Factors Mechanism and Epidemiology Research. Chemicals such as bisphenols, PFOS and aluminium have extensive research into their mechanism of action in cell lines and animal models...

Mucinous colorectal carcinoma (MUC CRC) dissemination into the tumor stroma and metastasis to multip

Epigenetic memory enables the stable propagation of gene expression patterns in response to transien

Centre for Genome Engineering and Maintenance is a network of cell and molecular biologists working to understand how the health and functionality of a cell