Sign in

Célia Souque

@celiasouque.bsky.social
1.6K followers 785 following 41 posts

Evolution | Genomics | AMR ECDC EUPHEM fellow at the Norwegian Institute of Public Health. Previously seen: Harvard Medical School Currently obsessed with plasmids 🦠

PostsRepliesMedia
Reposted by Célia Souque
Everyone's least favorite lab mate @kepatitis-c.bsky.social · 06/01/2026
🎉 New year, NEW PREPRINT! Bacteria exhibit astonishing genetic diversity, but where do new genes come from? My best friend Arya Kaul (/labmate in the @baym lab) investigates how advantageous deletions can spawn new genes - "deletion-born fusions." 🧵:
14930
Reposted by Célia Souque
Everyone's least favorite lab mate @kepatitis-c.bsky.social · 20/11/2025
What is the best strategy to win any contest? Eliminate your opponents of course. Recently, my friend @fernpizza.bsky.social showed how plasmids compete intracellularly (check out his paper published in Science today!). With @baym.lol, we now know they can fight. www.biorxiv.org/content/10.1...
37942
Reposted by Célia Souque
Ricardo León-Sampedro @rleonsampedro.bsky.social · 07/11/2025
🚨 Excited to share our new paper is out! 🎉 We show how interactions within gut microbiomes allow certain antibiotic-resistant E. coli strains to persist even without antibiotics, helping explain how resistance is maintained in the human gut. Now published in @natcomms.nature.com rdcu.be/eOf63
rdcu.be
Multi-layered ecological interactions determine growth of clinical antibiotic-resistant strains within human microbiomes
Nature Communications - The role of ecological factors in modulating the spread of antibiotic-resistance bacteria in the gut remains unclear. Here, the authors use anaerobic microcosms to study the...
24917
Reposted by Célia Souque
Louise Roer @louiseroer.bsky.social · 18/09/2025
✨Célia Souque just showcased the outcomes of the 12th Microbial Bioinformatics Hackathon at IMMEM XIV. She brilliantly presented the first sneak-peek of PORT – Plasmid Outbreak Reporting Tool! 🧬 Looking forward to continuing this collaboration with PORT! #IMMEM #Hackathon #Plasmids #ESGEM #ESGMAP
1248
Reposted by Célia Souque
Sofya Garushyants @garushyants.bsky.social · 15/09/2025
hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!
16988
Reposted by Célia Souque
Didier Mazel @amazeld.bsky.social · 23/06/2025
chng.it/jNJSnj2hjQ
chng.it
Avez-vous une minute pour aider cette campagne?
Sauvons BIOASTER : Un Appel Urgent pour la Recherche en Microbiologie !
011
Reposted by Célia Souque
ESCMID_ESGMAP @esgmap.bsky.social · 19/06/2025
ESGMAP is now on LinkedIn and Bluesky! We published our first newsletter (lnkd.in/dUe43t8y). It introduces us, our mission, activities, and ways to get involved. Fill out our members' survey, and associate your publications with the group. Follow us for updates on the mobile elements and plasmids.
054
Reposted by Célia Souque
Siân Owen @sianowen.bsky.social · 03/06/2025
The Wadsworth Center is expanding it's research focus on #virology /vector-borne diseases! www.asmcareerconnections.org/job/research-scientist-5-g-31/78488664/ This is a unicorn assistant prof equivalent position with 12-month hard money salary and no teaching commitments (!) Reposts appreciated 🙏
34961
Reposted by Célia Souque
Liana Merk @bacteriyay.bsky.social · 24/05/2025
(1/7) Very excited to share my first PhD preprint on the interactions of two of my favorite mobile genetic elements: phages and group II introns! www.biorxiv.org/content/10.1...
biorxiv.org
Prevalence of Group II Introns in Phage Genomes
Although bacteriophage genomes are under strong selective pressure for high coding density, they are still frequently invaded by mobile genetic elements (MGEs). Group II introns are MGEs that reduce h...
47019
Reposted by Célia Souque
Craig MacLean @craigmaclean.bsky.social · 08/05/2025
New Research Assistant position available in my lab to work on a project testing the efficacy of pills dependent #phage against clinical isolates of enteric bacteria . Part of a growing phage research theme in my lab my.corehr.com/pls/uoxrecru...
my.corehr.com
Job Details
22826
Reposted by Célia Souque
Jose A Escudero @jaescudero.bsky.social · 08/05/2025
🧪 Finally out after peer review, our work showing that "Mobile #Integrons carry Phage Defense Systems" is now published in Science 🎉 Short 🧵 www.science.org/doi/10.1126/...
science.org
Mobile integrons encode phage defense systems
Integrons are bacterial genetic elements that capture, stockpile, and modulate the expression of genes encoded in integron cassettes. Mobile integrons (MIs) are borne on plasmids, acting as a vehicle ...
1513680
Célia Souque @celiasouque.bsky.social · 25/04/2025
The link is not working for me 😔
110
Reposted by Célia Souque
Bram van Dijk 🏳️‍🌈 @bramvandijk.bsky.social · 24/03/2025
Cool preprint! The smallest Darwinian entity is a little smarter than we thought... www.biorxiv.org/content/10.1...
biorxiv.org
RNA-guided nucleases enable a gene drive of insertion sequences in plasmids
Mobile genetic elements (MGEs) and the interactions between them are a major source of evolutionary innovation. Insertion sequences, the simplest MGEs usually encoding only the necessary genes for tra...
0184
Célia Souque @celiasouque.bsky.social · 03/03/2025
Any idea when the abstract submission portal opens for IMMEM XIV? 😊 @esgem-sg.bsky.social
000
Reposted by Célia Souque
Randall Munroe @xkcd.com · 26/02/2025
RNA xkcd.com/3056
154177392542
Célia Souque @celiasouque.bsky.social · 21/02/2025
Ground-breaking work by one of the most amazing of scientists. A must read for all plasmids afficionado (and and any evolutionary biologist in general!)
083
Célia Souque @celiasouque.bsky.social · 06/02/2025
It seems really good but apparently rough around the edges regarding the UI, so I am waiting a bit for them to patch it first!
110
Reposted by Célia Souque
Michael Baym @baym.lol · 17/01/2025
This paper has been a long time coming: We looked at the genomes of historical bacterial samples over a century to look for trends of antibiotic resistance genes, finding multiple instances of them in infections before the age of antibiotics, but an increase in both frequency and mobility after
11304122
Reposted by Célia Souque
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 17/01/2025
Genomic resistance in historical clinical isolates increased in frequency and mobility after the age of antibiotics www.biorxiv.org/content/10.1101/202…
2173
Reposted by Célia Souque
Alexandre Almeida @alexmsalmeida.bsky.social · 10/01/2025
Delighted to share the first peer-reviewed paper from our team @camvetschool.bsky.social where we investigate the ecological dynamics of Enterobacteriaceae in the human gut #microbiome: www.nature.com/articles/s41... @naturemicrobiol.bsky.social
nature.com
Ecological dynamics of Enterobacteriaceae in the human gut microbiome across global populations - Nature Microbiology
Assessing more than 12,000 metagenomic samples from across the world using computational approaches, the authors determined interactions between species that co-colonize or co-exclude Enterobacteriace...
69348
Reposted by Célia Souque
Anna Dewar @annadewar.bsky.social · 08/01/2025
Our review is out in Nature Reviews Genetics! rdcu.be/d5AY2 We show how phylogeny-based methods can resolve the problem of non-independence in genomic datasets. These methods must be considered an essential part of the comparative genomics toolkit. @lauriebelch.bsky.social @stuwest.bsky.social
rdcu.be
A phylogenetic approach to comparative genomics
Nature Reviews Genetics - Controlling for phylogeny is essential in comparative genomics studies, because species, genomes and genes are not independent data points within statistical tests. The...
519494
Reposted by Célia Souque
Rachel M. Wheatley @rachelmwheatley.bsky.social · 30/12/2024
Sharing three fully funded PhD opportunities to join my lab at Queen’s to work on topics spanning bacterial pathogens, antibiotic resistance, microbial interactions, & mobile genetic elements 🦠. Closing dates in January and February, and open to international candidates 🌍 Projects detailed below ⬇️
43747
Reposted by Célia Souque
Michael Brockhurst @brockhurstlab.bsky.social · 04/12/2024
In case you missed it: @matthewjshepherd.bsky.social surveyed the clinical literature to reveal how #AMR evolves within patients, why eco/evo mechanisms vary among infections, & what we can do better to improve treatments www.nature.com/articles/s41... #MicroSky
nature.com
Ecological and evolutionary mechanisms driving within-patient emergence of antimicrobial resistance - Nature Reviews Microbiology
In this Review, Shepherd, Brockhurst and colleagues explore the clinical evidence in support of four major ecological and evolutionary mechanisms of within-patient antimicrobial resistance emergence i...
13718
Célia Souque @celiasouque.bsky.social · 03/12/2024
Gosh parts of me hate the concept of ChatGPT with a passion, but I have to acknowledge it's supremacy when trying to debug a Snakemake pipeline, which I am not convinced are made to be understood by humans 😅
030
Reposted by Célia Souque
Anita Williams @catanita.bsky.social · 02/12/2024
Volume 2 of the #AMR Starter Pack is here! go.bsky.app/EUY2FUJ Follow these amazing people along with those in Vol. 1 go.bsky.app/KkZfvrh And don't forget to pin the Antimicrobial Resistance feed to get all the AMR posts in one place bsky.app/profile/did:...
93622
Reposted by Célia Souque
Craig MacLean @craigmaclean.bsky.social · 27/11/2024
Don't know how to do polls in Bluesky, but am very curious to know how what the #microsky thinks. Genes that increase fitness in natural conditions are: A. Over-represented on plasmids B. Over-represented on the chromosome C. Evenly distributed between plasmids and the chromosome
511
Célia Souque @celiasouque.bsky.social · 01/12/2024
For circular plots, I have found that out of the box elderly BRIG beatsonlab.com/softwares/br... remains the best. Otherwise for more custom plots I usually go with circos-like packages (like pyCirclize in Python) but it is much more work
beatsonlab.com
BRIG
020
Célia Souque @celiasouque.bsky.social · 27/11/2024
That's low-key one of my favorite thing about Oslo - the city center is very often car free, and the few cars are often electric, which makes them much less audible. Going to back to a 'proper' big city (Stockholm) for a week felt weird!
0100
Reposted by Célia Souque
Willem van Schaik @wvschaik.bsky.social · 30/10/2024
Please sign up, it will be fun! Open for all with an interest in AMR and genomics (in the UK and elsewhere). www.targetamr.org.uk (and please give @target-amr.bsky.social a follow!)
targetamr.org.uk
TargetAMR – Reducing AMR through Genomics
52223
Célia Souque @celiasouque.bsky.social · 24/11/2024
Signed up! 😊
010
Reposted by Célia Souque
Ellie Rand @ellie-rand.bsky.social · 23/11/2024
Get ready to dance, our paper – Phage DisCo: targeted discovery of bacteriophages by co-culture – has been pre-printed! 🪩 This has been a really fun project to work on with @sianowen.bsky.social, @baym.lol, @nquinoneso.bsky.social, and our two talented undergrads Kesther and Carmen!
420577
Célia Souque @celiasouque.bsky.social · 22/11/2024
GenoFig is my new favorite one! Clinker breaks down a bit when you look at plasmid-sized sequences (100kb)
130
Célia Souque @celiasouque.bsky.social · 22/11/2024
Very glad to see this properly out and open access from my time with @baym.lol We've learnt so much about antibiotic resistance evolution already, and yet so many outstanding and fascinating questions remain, at all levels of selection. www.annualreviews.org/content/jour...
05521
Reposted by Célia Souque
Michael Baym @baym.lol · 21/11/2024
The first review article from my lab, helmed by @celiasouque.bsky.social, "From Petri Dishes to Patients to Populations: Scales and Evolutionary Mechanisms Driving Antibiotic Resistance" is now online and open access at Annual Reviews Microbiology: www.annualreviews.org/content/jour...
11295112
Célia Souque @celiasouque.bsky.social · 19/11/2024
Very excited to be on the way to #ESCAIDE in Stockholm, and in particular to meet old and new EPIET/EUPHEM fellows 😄 On that note, if you are related to the fellowship and are not on this starter pack, let me know! go.bsky.app/EDqC8CG
075
Reposted by Célia Souque
Michael Landis @landismj.bsky.social · 19/11/2024
Here's a starter pack for early career researchers in evolutionary biology. I prioritized the most-junior folks, and this list quickly filled up with undergrads, grad students, and postdocs. Might do another list later, but I'm tired. Have fun everyone! 🐒 #evobio go.bsky.app/MzND7nX
39265154
Célia Souque @celiasouque.bsky.social · 18/11/2024
Interested 😄
000
Célia Souque @celiasouque.bsky.social · 14/11/2024
📌
000
Reposted by Célia Souque
Elinne Becket, PhD @bielleogy.bsky.social · 13/11/2024
Phylogenetics skeeps: any recommendations for a review of different approaches for building phylogenetic trees?
142
Célia Souque @celiasouque.bsky.social · 13/11/2024
📌
010
Reposted by Célia Souque
Jerónimo Rodríguez-Beltrán @jerorb.bsky.social · 11/11/2024
I just made a starter pack on Ecology and Evolution of AMR. 🦠 ⚡ 💊 Feel free to suggest names and I’ll add them as soon as I can!! go.bsky.app/CwEzc79
336436
Célia Souque @celiasouque.bsky.social · 13/11/2024
📌
000
Célia Souque @celiasouque.bsky.social · 12/11/2024
📌
000
Célia Souque @celiasouque.bsky.social · 12/11/2024
📌
010
Célia Souque @celiasouque.bsky.social · 12/11/2024
📌
020
Reposted by Célia Souque
Eva Garmendia @evagaresp.bsky.social · 12/11/2024
If you follow me, you should definetely follow the @uac-uu.bsky.social account! I post there as part of my work as coordinator of the center, and will all be about #AMR and #antibiotics! Help me get the center’s words to the right audience!! 👇🏻👇🏻
042
Reposted by Célia Souque
Mel Lacey @mellacey.bsky.social · 11/11/2024
Microbiology Education and Outreach peeps, I tried to find all the folk here I could and make this, please let me know who I've missed and I'll add them go.bsky.app/QYgSwS6
174825
Reposted by Célia Souque
João Botelho @joaoftsbotelho.bsky.social · 10/11/2024
Mobile Elements Starter Pack on BlueSky! Interested in plasmids, phages, ICEs, transposons, integrons, and all things accessory genome? Follow this curated list of researchers and labs doing exciting work in mobile elements.
2910466
Célia Souque @celiasouque.bsky.social · 14/03/2024
Question for the (ex-)postdocs! I am co-corresponding author of soon-to-be-out paper (yay!), but my current academic email is tied with my postdoc. I hate putting an email that will become a dud, but feel personal (gmail) email look less professional? In that case, email of PI is also included.
010
Reposted by Célia Souque
Elisa Granato @prokaryota.bsky.social · 14/12/2023
Big career announcement!! A few weeks ago I was offered an interview and site visit for a tenure-track Professor of Microbiology position at a dream location. But - I declined! Here is why ... (TLDR: enthusiastically saying "No, thank you" to academia) #MicroSky 1/8
711621