Changing the way the world treats childhood leukemia In the world of pediatric cancer research, a program at the Children’s Hospital Research Institute of Manitoba (CHRIM) has reimagined the ways to p...

Childhood tumours often emerge not from an accumulation of mutations, but from disruptions in developmental programmes. This premise shaped the 44th Barcelon...

Robert F. Kennedy’s Jr. advisers are sparring over how far he should go on vaccines as health secretary.

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The lawsuit, filed Monday in US District Court for Massachusetts, was co-led by Andrea Campbell and asserts that the Trump administration’s changes violate the Administrative Procedure Act.

Garrido-Mesa and Brown review findings from TCR profiling studies in rheumatic diseases and discuss how improved study design might help elicit information about autoreactive T cell clones and their c...

Key PointsTyrosine-unphosphorylated STAT5 maintains HSCs.JAK inhibition promotes unphosphorylated STAT5 activity and maintains normal and myeloproliferativ

Leukemia - Targeting LMO2-induced autocrine FLT3 signaling to overcome chemoresistance in early T-cell precursor acute lymphoblastic leukemia

Yu and colleagues present a single-cell transcriptomic landscape of olfactory neuroblastoma, characterizing different tumor subtypes and cancer cell responses to drug treatments.

Researchers facing

Extracellular vesicles are being explored for various biomedical applications, but face challenges with regard to isolation, characterization and manufacturing. This Review delineates the physico-chem...