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Chris Bahl

@cdbahl.com
1.3K followers 84 following 62 posts

protein geek, founder and CEO of AI Proteins @aiproteins.com linkedin.com/in/cdbahl

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Chris Bahl @cdbahl.com · 18/09/2026
We always strive for our work to substantially benefit the greater scientific community, and it's such a thrill every time it happens. A massive thank you to @addgene.bsky.social for amplifying the impact of researchers everywhere! 🧵👇
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Protein Society @proteinsociety.bsky.social · 04/09/2026
📄 Facile, high-throughput protein purification enabled by high-efficiency protease elution (Fig. 2) Read more here: onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Facile, high‐throughput protein purification enabled by high‐efficiency protease elution
While advances in artificial intelligence have made protein design widely accessible, protein production and characterization remain a bottleneck. Protease-cleavable affinity tags are commonly used t...
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Protein Society @proteinsociety.bsky.social · 04/09/2026
🧬 Figure Friday AI is making protein design faster, but can protein production keep up? Edson Noriega, Chris Bahl & colleagues developed a high-throughput workflow for rapid protein purification, demonstrated across 96 diverse proteins.
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Rosetta Commons @rosettacommons.bsky.social · 18/08/2026
🧬 Want to stay updated on protein science? Check out the @bpdmc.org monthly presentation series! Recent topics: • Computational antibody design • Energy-based models & structure • De novo small-molecule induced changes Learn more, watch past presentations, and join the community at bpdmc.org.
 An announcement of the Boston Protein Design and Modeling Club’s monthly presentation series. It includes a picture of the Boston skyline with the club’s name over it. The text below it states, “Proteins, Presentations, and Peers; Boston Protein Design and Modeling Club (BPDMC) is an open community of computational protein engineers and modelers from both academia and industry. Visit their website to watch their monthly presentation series and to join the club. Learn more at bpdmc.org.” The background is a light teal with some hexagons on it. The Rosetta Commons logo is in the upper right corner.
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Addgene @addgene.bsky.social · 10/08/2026
Power up your protein purification with a new SUMO protease construct from @cdbahl.com and team! Find individual plasmids here: www.addgene.org/browse/artic... Or get the full benchmark set: www.addgene.org/kits/bahl-su...
addgene.org
Addgene: Facile, high-throughput protein purification enabled by high-efficiency protease elution.
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Chris Bahl @cdbahl.com · 05/08/2026
Every protein designer knows that producing & testing designed proteins is a foundational capability for our field, & this is still pretty challenging for a lot of folks. This is why I'm delighted to share our work to make high-throughput protein production more accessible dx.doi.org/10.1002/pro....
dx.doi.org
Facile, high‐throughput protein purification enabled by high‐efficiency protease elution
While advances in artificial intelligence have made protein design widely accessible, protein production and characterization remain a bottleneck. Protease-cleavable affinity tags are commonly used t....
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Nick Polizzi @nickpolizzi.bsky.social · 05/08/2026
We can design "static" binders routinely now, but design of "dynamic" shape-changing proteins has remained quite hard. Jeffrey Chang and I asked: why can't we couple small-molecule binding to shape change? After all, natural proteins do it every day. In a new preprint, we show how it can be done. 🧵
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AI Proteins @aiproteins.com · 25/06/2026
Three weeks ago, we welcomed the local scientific community to join us at our headquarters in Kenmore Square for the inaugural lecture in the AI Proteins Seminar Series. Our speaker Neil King from @uwproteindesign.bsky.social delivered a superb seminar. Check it out 👇 youtu.be/OPRMfRnlx1k
youtu.be
Neil King: ML-based design of nanoparticle vaccines (AI Proteins Seminar Series)
YouTube video by AI Proteins
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Protein Society @proteinsociety.bsky.social · 03/06/2026
⏰ Tomorrow! Join our webinar, Introduction to Protein Design for Africa, featuring speakers from AI Proteins, STEAMulater, Minimal Bio, and Nostrum Biodiscovery. Learn how protein design is advancing innovation and accessibility around the world! Register: us06web.zoom.us/webinar/regi...
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AI Proteins @aiproteins.com · 03/06/2026
Thank you to everyone who attended the inaugural lecture in the AI Proteins Seminar Series today. Neil King @kinglabipd.bsky.social gave a fantastic talk to a packed house!
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AI Proteins @aiproteins.com · 01/06/2026
We're delighted to kick off our new seminar series, and the inaugural speaker is none other than Neil King from the Institute for Protein Design, University of Washington "ML-based design of nanoparticle vaccines" June 3rd, 2026 12:00 PM – 1:00 PM EDT
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Martin Pacesa @martinpacesa.bsky.social · 14/04/2026
Really fun and challenging (!) discussion with @cdbahl.com on BindCraft, the state of binder design, the oustanding challenges and perhaps also some misconceptions in the field 💫 www.healthtech.com/the-chain/ma...
healthtech.com
Episode 84 Martin Pacesa on BindCraft An Automated Pipeline for De Novo Protein Binder Design
April 14, 2026 | How is BindCraft, the automated pipeline for de novo protein binder design, changing the protein design industry? Martin Pacesa, assistant professor of pharmacology at the University ...
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Chris Bahl @cdbahl.com · 09/04/2026
I never imagined this would happen ~8+ years ago. Just, wow. I'm so grateful to everyone in this community and for all the support and help from the many people that made it possible.
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Chris Bahl @cdbahl.com · 31/03/2026
We've got two more positions open for RAs to join AI Proteins! One opening is for our Protein Characterization group led by Alyssa Anderson, and the other is for our Biochemistry group led by Edson Carcamo. These wet lab roles are a perfect for college students who are graduating this spring.
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Chris Bahl @cdbahl.com · 09/03/2026
We're recruiting a Research Associate to join our Bioprocess Development team. This is a wet lab role ideally suited for someone graduating college this spring who is excited to join a team pioneering a new therapeutic modality Check it out! 👇 www.aiproteins.com/open-positio...
aiproteins.com
Research Associate in Bioprocess Development | AI Proteins
Mar 06, 2026
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Chris Bahl @cdbahl.com · 05/03/2026
I had a great time nerding out about protein design with @nickpolizzi.bsky.social, and an enormous thanks to @biotechtv.bsky.social and @massbio.bsky.social for hosting us! www.biotechtv.com/post/chris-b...
biotechtv.com
AI Proteins Founder & CEO Chris Bahl and Dana-Farber Cancer Institute Investigator Nick Polizzi discuss the current state of protein design and new innovations that are around the corner
Both experts in the field, one with an academic view and one from industry, they discuss what can be done today with protein design, new innovations coming in the next year or two, and how they think ...
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Chris Bahl @cdbahl.com · 27/02/2026
Speaking as someone who had a career in academia before industry - there are many things I love about academia, but my job satisfaction is higher in industry. I hope things get better for all my friends in academia, because switching isn't the solution for everyone. www.nature.com/articles/d41...
nature.com
Industry scores higher than academia for job satisfaction
Nature’s salary survey finds that industry researchers are more positive about their careers. Academia must raise its game.
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Boston Protein Design and Modeling Club @bpdmc.org · 21/02/2026
We've got Jeff Gray (graylab.jhu.edu) coming to present this month!! Wednesday, February 25th 2026, starting at 7pm EST in Room 181, Building 68, @MIT "Antibody language models vs. biology; protein docking denoising diffusion models vs. physics" bpdmc.org
bpdmc.org
schedule
introduction and membership Boston Protein Design and Modeling Club (BPDMC) is a community of computational protein engineers and modelers from both academia and industry. While we are based in Boston...
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Chris Bahl @cdbahl.com · 21/11/2025
Thanks for the fun conversation Ingmar Schuster, and for the opportunity to share more about what we're building at @aiproteins.com! youtu.be/7O0s5AY46U0
youtu.be
Chris Bahl on the Conundrum of Biotech Platforms
YouTube video by Provolut
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Chris Bahl @cdbahl.com · 20/11/2025
I appreciate all the congratulations for our Series A! I also want to make sure we don't forget an important truth Funding is not the finish line. We're grateful for the resources we have, and my promise is that we'll continue to do everything in our power to make a difference
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Chris Bahl @cdbahl.com · 18/11/2025
The next chapter for AI Proteins @aiproteins.com is officially underway! I'm absolutely delighted to share that we’ve closed a $41.5M Series A led by Mission BioCapital and Santé Ventures. endpoints.news/boston-biote...
endpoints.news
Exclusive: AI Proteins raises $42M Series A, and will launch miniproteins into hub-and-spoke model
AI Proteins raises $42M Series A for minibinder drug development, led by Mission BioCapital & Santé Ventures. CEO Chris Bahl aims to target TNFR1 with first candidate.
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Chris Bahl @cdbahl.com · 11/11/2025
My new @ted.com talk from the main stage just went live! go.ted.com/chrisbahl 🧵👇
go.ted.com
The secret language of cells — and how to "speak" it
What if medicines could "speak" directly to your cells? Protein designer and TED Fellow Chris Bahl introduces a new generation of miniproteins: AI-designed medicines that can deliver detailed instruct...
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Boston Protein Design and Modeling Club @bpdmc.org · 17/10/2025
Join us in Room 181, Building 68 @mit.edu on October 22nd 2025 @ 7pm EDT to see @grocklin.bsky.social present a mind blowing amount of data and learn what becomes possible at this scale "Predicting protein folding stability and aggregation propensity using large-scale experiments" bpdmc.org
bpdmc.org
schedule
introduction and membership Boston Protein Design and Modeling Club (BPDMC) is a community of computational protein engineers and modelers from both academia and industry. While we are based in Boston...
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Chris Bahl @cdbahl.com · 03/09/2025
We're looking for a mass spec expert to join our team at @aiproteins.com! This position is ideal for a freshly-minted PhD grad (or someone who will graduate within the next 6 months or less), or a rockstar scientist who earned their skills on the job in biotech
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Guilherme M. Arantes @garantes.bsky.social · 01/09/2025
🎥 Neste videocast produzido junto do @ieausp.bsky.social, tive uma conversa inspiradora com o Anderson Soares (UFG), @alexandre-cf.bsky.social e o @cdbahl.com sobre como a IA está moldando o futuro da biologia e da saúde humana. Assista aqui 👉 www.youtube.com/watch?v=qQbZ...
youtube.com
Inteligência Artificial Aplicada às Ciências da Vida
YouTube video by Instituto de Estudos Avançados da USP
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AI Proteins @aiproteins.com · 26/08/2025
Congratulations to Dr. James Bowman on his promotion to Chief Technology Officer! www.businesswire.com/news/home/20...
businesswire.com
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Chris Bahl @cdbahl.com · 26/08/2025
I am overjoyed to announce that James Bowman has been promoted to Chief Technology Officer at @aiproteins.com! 🧵👇
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Chris Bahl @cdbahl.com · 12/07/2025
This was a lot of fun - thanks so much @yossefbaidi.bsky.social and @fang-xie.bsky.social ‪for the great conversation, and for your passion and excitement for biotech and entrepreneurship!
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Nick Polizzi @nickpolizzi.bsky.social · 28/04/2025
Super excited to share a new preprint from our lab on design of small-molecule binding proteins using neural networks! The paper has a bit of everything. A new graph neural network, new design algorithms, and experimental validation. www.biorxiv.org/content/10.1... 🧵🧪
biorxiv.org
Zero-shot design of drug-binding proteins via neural selection-expansion
Computational design of molecular recognition remains challenging despite advances in deep learning. The design of proteins that bind to small molecules has been particularly difficult because it requ...
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Institute for Protein Innovation @ipiproteins.bsky.social · 01/05/2025
#IPISeminar alert 🔔 Friday at 2 p.m. ET, Chris Bahl of AI Proteins will share the challenges of incorporating #artificialintelligence into #proteindesign & the impact reimagined #miniproteins can have on therapeutics. Join us through the QR code or follow the Zoom link on our calendar! rb.gy/xcee9l
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Chris Bahl @cdbahl.com · 15/04/2025
It was an honor to speak from the main stage at TED last week about our work at AI Proteins Our mission is to design the next generation of therapeutics built from de novo #miniproteins, and this was an unbelievable opportunity to help shape the broader conversation about the future of biologics
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Chris Bahl @cdbahl.com · 12/02/2025
Big news to share! Phil Brandish has joined our team and will lead drug development efforts at AI Proteins. Phil is a rockstar, with a stellar track record and years of experience successfully bringing molecules into the clinic at Merck and Bicycle Therapeutics.
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Chris Bahl @cdbahl.com · 07/01/2025
I’m excited to share that I am now the CEO of AI Proteins @aiproteins.bsky.social! I’m grateful to continue leading this exceptional team as we build upon the strong foundation that we’ve established since launching the company in 2021. www.businesswire.com/news/home/20... 🧵👇
businesswire.com
AI Proteins Appoints Founder Dr. Chris Bahl as Chief Executive Officer; Company to Present at Biotech Showcase 2025 during J.P. Morgan Healthcare Week
AI Proteins, Inc., a pioneering company utilizing artificial intelligence to design novel protein therapeutics, announces the appointment of its found
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Chris Bahl @cdbahl.com · 20/12/2024
So, I might have ended up on the jumbotron at the Celtics game proudly wearing my @aiproteins.bsky.social colors
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Chris Bahl @cdbahl.com · 17/12/2024
Mireia Solà Colom gave an incredible seminar at @bpdmc.bsky.social last week, and I'm very excited for her to share some details about what we've built at @aiproteins.bsky.social and how well our #miniproteins perform as therapeutics
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Chris Bahl @cdbahl.com · 08/12/2024
So excited for my postdoc mentor David Baker giving his Nobel Prize lecture in Stockholm!!
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The Royal Swedish Academy of Sciences @scienceacademyswe.bsky.social · 05/12/2024
Today, several #NobelPrize Laureates arrive in Stockholm, warmly welcomed by Hans Ellegren. Here we see David Baker stepping off the plane at Arlanda. This week is packed with inspiration, press conferences and lectures, so stay tuned! 🌟 @uofwa.bsky.social @hhmi.bsky.social #Science #AcademicSky
Hans Ellegren Welcoming David Baker at Stockholm Arlanda.
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Maru Llases @mellases.bsky.social · 03/12/2024
Exciting times at @aiproteins.bsky.social ! We are getting so close to see our drugs helping patients! www.fiercebiotech.com/biotech/bris...
fiercebiotech.com
Bristol Myers Squibb taps AI Proteins in drug discovery collaboration worth up to $400M
Bristol Myers Squibb has
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AI Proteins @aiproteins.com · 03/12/2024
and more coverage from Endpoints News @endpts.com endpts.com/bms-inks-dea...
endpts.com
BMS inks deal with AI Proteins; Terns’ early-stage leukemia data
Bristol Myers Squibb partners with AI Proteins for miniprotein development, with up to $400M in milestones. Terns Pharmaceuticals reports positive Phase 1 data for TERN-701. Six biotechs seek Hong Kon...
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AI Proteins @aiproteins.com · 03/12/2024
You can read more about our exciting new collaboration with Bristol Myers Squibb in this coverage from Fierce Biotech www.fiercebiotech.com/biotech/bris...
fiercebiotech.com
Bristol Myers Squibb taps AI Proteins in drug discovery collaboration worth up to $400M
Bristol Myers Squibb has
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AI Proteins @aiproteins.com · 03/12/2024
AI Proteins is excited to partner with @bms-news.bsky.social to develop novel miniprotein-based therapeutics. This collaboration will leverage our cutting-edge AI-driven platform to design and optimize miniproteins with the potential to transform patient outcomes www.businesswire.com/news/home/20...
businesswire.com
AI Proteins Announces Research Collaboration and Option Agreement with Bristol Myers Squibb for Miniprotein-Based Therapeutics Valued up to $400M
AI Proteins, Inc., a biotechnology company that utilizes computational de novo protein design to create therapeutic miniproteins, today announced that
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Chris Bahl @cdbahl.com · 03/12/2024
We've got some very exciting news to share! businesswire.com/news/home/20... and here's a 🧵 about the journey from academia to @aiproteins.bsky.social
businesswire.com
AI Proteins Announces Research Collaboration and Option Agreement with Bristol Myers Squibb for Miniprotein-Based Therapeutics Valued up to $400M
AI Proteins, Inc., a biotechnology company that utilizes computational de novo protein design to create therapeutic miniproteins, today announced that
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Boston Protein Design and Modeling Club @bpdmc.org · 22/11/2024
There's just one meeting left in 2024, and we have a spectacular seminar by Mireia Solà Colom lined up for you! Join us at 7pm in Room 181, Building 68, MIT on Wednesday, December 11th. "De novo design of miniprotein-based natural killer cell engagers" See you there & Happy Thanksgiving! bpdmc.org
bpdmc.org
schedule
introduction and membership Boston Protein Design and Modeling Club (BPDMC) is a community of computational protein engineers and modelers from both academia and industry. While we are based in Boston...
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AI Proteins @aiproteins.com · 16/11/2024
Our founder, President and CSO Chris Bahl @cdbahl.bsky.social went to the Falling Walls Science Summit last week to explain how we make #miniprotein therapeutics with unprecedented ability to control cellular behavior - you can check out the recording 👇 www.youtube.com/live/zB6-iUB...
youtube.com
YouTube
Share your videos with friends, family, and the world
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