An epidemic’s expected course is determined by the magnitude and timing of a typical person’s infectiousness — captured, in turn, by the basic reproduction number and the generation-time distribution....

Abstract. Natural selection encodes learned information in the genome. Learned solutions may be tuned specifically to past challenges, failing in altered e

“As another Ebola outbreak unfolds, we cannot repeat the mistakes of the past,” writes Krutika Kuppalli.

Incorporating vaccination into mathematical models appears deceptively simple: models integrate vaccine-derived protections, such as reduced susceptibility to infection, using parameters informed by e...

HHS proposes spending $2 billion a year to re-create systems the U.S. accessed through the WHO at a fraction of the cost, according to officials briefed on the matter.

Declining vaccine coverage across the United States has increased the risk of outbreaks of vaccine-preventable diseases. Even when vaccines have low primary failure rates, conventional epidemic theory...

Abstract. While widely used to study vaccine effectiveness, test-negative designs (TNDs) also provide a platform for identifying and quantifying immunologi

Published in Future Virology (Vol. 20, No. 12, 2025)

Epistorm-Mix provides individual-level contact data and contacts patterns characterization relevant for the spread of respiratory infectious diseases within the US population.

The importance of playing the long game when it comes to pandemic surveillance