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Marc Lipsitch

@mlipsitch.bsky.social
1.9K followers 461 following 70 posts

Professor of Epidemiology Harvard Chan SPH, Director, @ccdd-hsph.bsky.social. Views my own.

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Marc Lipsitch @mlipsitch.bsky.social · 06/10/2025
cisac.fsi.stanford.edu/content/cisa... In my new role at @stanfordcisac.bsky.social, I'm recruiting for a postdoc to define how benefits of risky research should be evaluated. w Tony Mills of @notredame.bsky.social . #philsci #biosecurity #scipolicy
cisac.fsi.stanford.edu
CISAC Fellowship Program
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Marc Lipsitch @mlipsitch.bsky.social · 09/09/2025
New preprint reporting a large piece of work by Katherine Jia to define estimands and estimators for direct impact of vaccines with arbitrary rollout schedules arxiv.org/abs/2509.05508 with Alyssa Bilinski, @chrisboyer.bsky.social and me
arxiv.org
Defining and Estimating Outcomes Directly Averted by a Vaccination Program when Rollout Occurs Over Time
During the COVID-19 pandemic, estimating the total deaths averted by vaccination has been of great public health interest. Instead of estimating total deaths averted by vaccination among both vaccinat...
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Christophe Fraser's Group @christophraser.bsky.social · 26/08/2025
New paper: we argue that a promising approach for studying mpox vaccine effectiveness in Central Africa to incorporate mpox vaccination + testing data into existing cohort studies, especially those for HIV/STIs. www.thelancet.com/journals/ebi...
thelancet.com
Clade I mpox vaccination: strategies for deployment and evaluation
Clade I mpox continues to spread in Central Africa with no sign of abating,1 however very few doses of vaccine have been deployed. Mpox vaccination strategies using either of the licenced vaccines, MV...
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Marc Lipsitch @mlipsitch.bsky.social · 25/08/2025
Very pleased to share this newly published work with Aishani Aatresh, part of her exceptional Harvard undergrad thesis. journals.asm.org/doi/10.1128/... .
journals.asm.org
What is the relationship between viral prospecting in animals and medical countermeasure development? | mBio
Sampling in animal populations to detect novel viruses before they infect humans has been a major activity justified by several considerations, notably by the idea that finding such viruses will stimu...
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CCDD @ccdd-hsph.bsky.social · 21/07/2025
Check out "Are We Prepared for the Next Pandemic?"- CCDD Director, @mlipsitch.bsky.social's conversation with Sam Harris, host of the Making Sense podcast. www.samharris.org/podcasts/mak...
samharris.org
Sam Harris | #425 - Are We Prepared for the Next Pandemic?
Sam Harris speaks with Marc Lipsitch about pandemic preparedness.
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Elizabeth Warren @warren.senate.gov · 30/06/2025
Republicans, before you vote to close 1 of 4 nursing homes, can you update us on where those people will go? Maybe call a few seniors in your state and go over plans for where they go next? Or call the son whose dad has dementia and tell him how he can be a full-time caregiver?
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CCDD @ccdd-hsph.bsky.social · 24/06/2025
A new study by Julia Deichmann, @mlipsitch.bsky.social and collaborators at the Sheba Medical Center, Israel uses mathematical modeling to predict antibody kinetics and duration of protection against SARS-CoV-2 following vaccination using sparse serological data. Read it here at bit.ly/43XY9mK
bit.ly
Predicting antibody kinetics and duration of protection against SARS-CoV-2 following vaccination from sparse serological data
Author summary Vaccination against SARS-CoV-2 has played a key role during the COVID-19 pandemic to lower transmission rates and reduce the number of severe cases. This is due to a vaccine-induced ris...
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CCDD @ccdd-hsph.bsky.social · 25/06/2025
New tool for pangenome analysis! CLARC refines bacterial gene clusters using functional annotation + linkage—not just sequence. New publication by @indragon.bsky.social & collaborators, advised by @mlipsitch.bsky.social & @billhanage.bsky.social. Read more at bit.ly/4ek0Y51
bit.ly
Linkage-based ortholog refinement in bacterial pangenomes with CLARC
Abstract. Bacterial genomes exhibit significant variation in gene content and sequence identity. Pangenome analyses explore this diversity by classifying g
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Marc Lipsitch @mlipsitch.bsky.social · 20/06/2025
Deeply affecting article by an @hsph.harvard.edu PhD student denied the opportunity to graduate due to blanket exclusion of Sierra Leone citizens by the US Government. A very particular example of pointless cruelty by the US Government. www.theguardian.com/global-devel...
theguardian.com
What it’s really like … to know I’m going to miss my Harvard graduation because of Trump’s travel ban
Like many other international students I have had my educational dreams suspended without reason – and learned plenty about racism and resilience
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Marc Lipsitch @mlipsitch.bsky.social · 09/06/2025
Remarkable open letter to the director from NIH staff on the health, financial,academic freedom, and other impacts of changes at the agency. www.standupforscience.net/bethesda-dec...
standupforscience.net
Bethesda Declaration — STAND UP FOR SCIENCE
Support NIH Staff Now!
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Michael Baym @baym.lol · 31/05/2025
The goal is plainly and literally to cut the number of people involved in basic science in the US by 70%
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Ferric Fang, MD @fangferric.bsky.social · 31/05/2025
"The policy’s narrow-mindedness will make America small again.” I am simply at a loss to express how stupid this is. www.nytimes.com/2025/05/30/b...
nytimes.com
Denying Visas to Chinese Students Could Backfire on America
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Marc Lipsitch @mlipsitch.bsky.social · 29/05/2025
Great piece by @hsph.harvard.edu colleague Maitreyi Mazumdar about how NIH's evisceration of overseas research collaborations harm the US as well as the partner countries www.bostonglobe.com/2025/05/29/o...
bostonglobe.com
NIH cuts have doomed my research in Bangladesh — but US citizens will pay too - The Boston Globe
Global partnerships have led to major scientific breakthroughs and saved millions of lives. Now, those collaborations are in jeopardy.
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Marc Lipsitch @mlipsitch.bsky.social · 27/05/2025
The Department of Health and Human Services has a process for making and updating recommendations like this, using expert scientists and clinicians. RFK is deliberately putting Americans' health at risk and sidestepping good science for political reasons.
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Jasmin Abdel Ghany @jasminabdelghany.bsky.social · 26/05/2025
The Demographic and Health Survey (DHS) Program was central in improving the evidence base for health policies and interventions, particularly in Sub-Saharan Africa and Central & Southern Asia - figure by @aasli.bsky.social. Our preprint on the termination of the DHS Program: osf.io/preprints/so...
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Bailey Bowcutt @baileybowcutt.bsky.social · 22/05/2025
I'm a current Harvard graduate student and I found out today that I had my NSF GRFP terminated without notification. I was awarded this individual research fellowship before even choosing Harvard as my graduate school
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Marc Lipsitch @mlipsitch.bsky.social · 22/05/2025
Please consider a comment today if you are in the US. See the advice (shared from an email I received) in the follow-up posts below this one. Tomorrow is the deadline. This is an important part of scientific freedom in this country.
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Marc Lipsitch @mlipsitch.bsky.social · 22/05/2025
Time Sensitive: Public comment on Schedule F (removing civil service protections for many federal employees INCLUDING THOSE WITH AUTHORITY OVER GRANTS) ends tomorrow. Notice is here: www.govinfo.gov/content/pkg/... . Comment here (green button) www.federalregister.gov/documents/20... .
govinfo.gov
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Marc Lipsitch @mlipsitch.bsky.social · 22/05/2025
An easily overlooked consequence of research funding cancellations: completed research these days requires hundreds to several thousand dollars to be published due to publication fees from journals. Without support for these fees many pieces of scientific work will be near invisible.
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Marc Lipsitch @mlipsitch.bsky.social · 21/05/2025
This is pure authoritarianism. www.nytimes.com/2025/05/21/u...
nytimes.com
If Justice Dept. Can’t Prosecute Trump’s Foes, It Will ‘Shame’ Them, Official Says
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Stand Up for Science! @standupforscience.net · 19/05/2025
🎓 The GOP’s reconciliation bill is a direct hit on higher ed: – $351B in cuts education & workforce programs – eliminating subsidized student loans – Taxes on scholarships & endowments – & more. ACE calls it a “full-out assault” on access to college. Read below ⬇️ www.acenet.edu/News-Room/Pa...
acenet.edu
House Reconciliation Bill Targets Higher Education with Deep Cuts and Tax Hikes
A budget reconciliation bill advancing in the House of Representatives proposes hundreds of billions of dollars in cuts to student aid, imposes new taxes on colleges and universities, and jeopardizes ...
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Linda Barlow @bizzarlow.bsky.social · 20/05/2025
Proposed cut to NIH for fiscal 2026- $18 billion www.whitehouse.gov/wp-content/u...
whitehouse.gov
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Marc Lipsitch @mlipsitch.bsky.social · 20/05/2025
Important public service reporting from @statnews.com on how people are getting their NIH grants reinstated www.statnews.com/2025/05/19/r...
statnews.com
Scientists are pushing to get their grants reinstated — and some are winning
The grant termination letters say there are no appeals. Yet dozens of appeals have succeeded as biomedical researchers lobby and sue to restore funding.
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Megan Behringer @megbehri.bsky.social · 09/05/2025
Given that there are 435 voting members of Congress, I would have hoped for more than 25% of House members to support American innovation in science and technology. 112? That’s it? No one else wants answers?!?!
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Sonja Lehtinen @sonjalehtinen.bsky.social · 23/04/2025
Looking for examples of beautiful, controversial or impactful microbial modelling papers - ideally a mixture of the above! It’s for teaching in the context of microbial eco/evo/epi. The modelling should be relatively easy to understand for a master’s student with a biology background.
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Pleuni Pennings @pleunipennings.bsky.social · 23/04/2025
Love this initiative!
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People For the American Way @peoplefor.bsky.social · 22/04/2025
Breaking: Over 150 college presidents across the country just signed a letter condemning the Trump administration’s threats to dictate their policies. “We speak with one voice against the unprecedented government overreach now endangering American higher education.”
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Marc Lipsitch @mlipsitch.bsky.social · 17/04/2025
New Brief Report out in @pnas.org with Katherine Budeski: www.pnas.org/doi/10.1073/... Focusing a virus risk ranking tool on prediction -- highlighting the importance of training models for viral emergence only on data available before emergence has happened.
pnas.org
Focusing a viral risk ranking tool on prediction | PNAS
Preparing to rapidly respond to emerging infectious diseases is critical. SpillOver: Viral Risk Ranking is an open-source tool developed to assess ...
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Carl T. Bergstrom @carlbergstrom.com · 19/03/2025
1. For the past thirty years I've had the best job in the world. 
I've had the opportunity to follow my curiosity; explore the workings of nature and society; mentor students and junior colleagues in the same process; and teach generations of students about it all.
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Carl T. Bergstrom @carlbergstrom.com · 11/04/2025
College Republicans: "Women, amirite?" "Wait, you hate women? I hate blacks! We have so much in common!" "Wou guys hate women and blacks? I hate the capital gains tax!" "Bro!" College Democrats: "Well actually, your expression of solidarity for trafficked migrants failed to acknowledge...."
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Brennan Center @brennancenter.org · 10/04/2025
BREAKING: The House will vote on the SAVE Act today. If this bill becomes law, millions of American citizens could be blocked from voting. 1/
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Carl T. Bergstrom @carlbergstrom.com · 05/04/2025
I've already had two federal grants terminated and face a 33% pay cut due to future terminations. It's painful, but not as painful as the conversations I'm having every day with brilliant trainees in graduate school and postdoctoral positions who see little future for themselves in US science.
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Marc Lipsitch @mlipsitch.bsky.social · 09/04/2025
New commentary on pandemic surveillance and the need to have it be repeatable/continuous for updating, out in @pnas.org with Freya Shearer of Uni Melbourne: www.pnas.org/doi/10.1073/...
pnas.org
The importance of playing the long game when it comes to pandemic surveillance | PNAS
The importance of playing the long game when it comes to pandemic surveillance
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Marc Lipsitch @mlipsitch.bsky.social · 06/04/2025
New preprint on how to approach antimicrobial use and resistance from a causal perspective led by Juan Gago and @cboyer.bsky.social @ccdd-hsph.bsky.social www.medrxiv.org/content/10.1...
medrxiv.org
How should we study the indirect effects of antimicrobial treatment strategies? A causal perspective.
Effective antimicrobial stewardship requires unbiased assessment of the benefits and harms of different treatment strategies, considering both immediate patient outcomes and patterns of antimicrobial ...
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CCDD @ccdd-hsph.bsky.social · 20/03/2025
New preprint by Hanage lab researchers Ilan Rubin, Mary Bushman, and Dr. @billhanage.bsky.social, with Dr. @mlipsitch.bsky.social: Seasonal forcing and waning immunity drive the sub-annual periodicity of the COVID-19 epidemic. Available at bit.ly/4htOSX1
bit.ly
Seasonal forcing and waning immunity drive the sub-annual periodicity of the COVID-19 epidemic
Seasonal trends in infectious diseases are shaped by climatic and social factors, with many respiratory viruses peaking in winter. However, the seasonality of COVID-19 remains in dispute, with signifi...
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The American Association of Immunologists @aai.org · 06/03/2025
AAI encourages members and friends of #immunology to #StandUpforScience on March 7. Join the rally in Washington, D.C., or participate in the National Day of Action to uphold the integrity of science, protect its accessibility, and ensure its benefits serve all people! standupforscience2025.org
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Rachel Levinson-Waldman @rlevinsonwaldman.bsky.social · 06/03/2025
This is dangerous and frankly anti-democratic. This is not how a healthy democracy functions. www.nytimes.com/2025/03/06/u...
nytimes.com
Fearing Retribution, Trump Critics Muzzle Themselves
People say they are intimidated by online attacks from the president, concerned about harm to their businesses or worried about the safety of their families.
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Office of Mayor Michelle Wu 吳弭 @mayorwu.boston.gov · 05/03/2025
If Republicans in Congress want to help make our country safe, I have some ideas for them.
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Office of Mayor Michelle Wu 吳弭 @mayorwu.boston.gov · 05/03/2025
Boston doesn’t listen to kings.
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Marc Lipsitch @mlipsitch.bsky.social · 06/03/2025
Mayor @mayorwu.boston.gov told the truth to a congressional committee yesterday and made me proud to be a Bostonian and proud to have such a great mayor www.boston.com/news/local-n...
boston.com
Before Congress, Wu touts Boston’s safety record, slams ‘false narrative’
Boston Mayor Michelle Wu will defend the city's sanctuary policies, which limit cooperation between ICE and local police.
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Rabbi Danya Ruttenberg @theradr.bsky.social · 05/03/2025
🔥 Meirav Solomon KILLS IT, placing responsibility for antisemitism exactly where it belongs: "it is not student protesters, but the bloody legacy of Pittsburgh and Poway, Charlottesville and the Capitol riots... Trump has highlighted and platformed neo-Nazis and white supremacists."
youtube.com
J Street U Vice President Meirav Solomon's Testimony in the Senate Judiciary Hearing on Antisemitism
YouTube video by J Street
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Marc Lipsitch @mlipsitch.bsky.social · 05/02/2025
I just joined APHA bit.ly/3tPy1KU -- a strong advocate for public health right now. Encourage others to do the same!
bit.ly
APHA Membership
Join APHA. Together, we really can make a difference.
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Marc Lipsitch @mlipsitch.bsky.social · 29/01/2025
This should be really interesting.
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Marc Lipsitch @mlipsitch.bsky.social · 26/01/2025
Follow the whole @harvardchanschool.bsky.social Starter Pack here bsky.app/starter-pack... Including @causalab.bsky.social , @harvardcchange.bsky.social , and numerous faculty.
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Marc Lipsitch @mlipsitch.bsky.social · 24/01/2025
Thrilled that this work by Lerato Magosi with many colleagues is now out as a preprint www.medrxiv.org/content/10.1.... It suggests results from treatment-as-prevention HIV cluster-randomized trials are lower than many expected due to significant "spillover" of infections from untreated communities
medrxiv.org
Unpacking sources of transmission in HIV prevention trials with deep-sequence pathogen data – BCPP/ Ya Tsie study
To develop effective HIV prevention strategies that can guide public health policy it is important to identify the main sources of infection in HIV prevention studies. Accordingly, we devised a statis...
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Marc Lipsitch @mlipsitch.bsky.social · 10/01/2025
From @harvardchanschool.bsky.social on a point often forgotten in the discussion on regulating risky research: very little evidence to date that it actually helps public health hsph.harvard.edu/news/little-.... For details see academic.oup.com/jid/article/... and www.cidrap.umn.edu/avian-influe...
hsph.harvard.edu
Little to be gained through ‘gain-of-function’ research, says expert | Harvard T.H. Chan School of Public Health
According to Marc Lipsitch, professor of epidemiology at Harvard Chan School, the risks of infectious disease "gain-of-function" research outweigh the potential benefits—which aren’t as significant as...
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Marc Lipsitch @mlipsitch.bsky.social · 27/12/2024
A terrific new review, super useful for getting a sense of the broad field and existing techniques, with good ideas about future directions.
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Gregg Gonsalves @gregggonsalves.bsky.social · 20/12/2024
New Orleans steps up. We need to support them.
Statement on vaccines by New Orleans Health Department.
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Sam Horwich-Scholefield @samhorwich.bsky.social · 21/12/2024
"Medical societies can speak out," Georges Benjamin, MD, executive director of the American Public Health Association, said... "The nursing societies can speak up. The hospital association can speak up. This is going to create business -- tragic business -- for the hospitals."
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