Sassano et al. identify endoplasmic reticulum–mitochondria contact sites as the intracellular location where phospholipid peroxidation first occurs to promote ferroptosis. Manipulating these contact s...

Exhaustion is the functional deterioration of T cells following chronic stimulation. Here, Wu et al. show that mitochondrial dysfunction drives T cell exhaustion by inhibiting HIF-1α degradation and ...

Stress-associated catecholamines promote CD8+ T cell exhaustion through the β1-adrenergic receptor, and blocking β-adrenergic signalling may help restore anti-tumour functions.

Today in Science and science: Hemoglobin isn’t just for red blood cells, gray whales’ future not so certain with climate change, and more

Die schweren Erdbeben von Herat gehören zu einer rätselhaften Klasse von Beben, die unerwartet zuschlagen kann

Let's hear it for these brilliant and inspiring scientists, docs, engineers, and coders, from Arrow's Felicity to The X-Files' Scully.

The official journal of the British Society for Rheumatology. Publishes high-quality scientific (basic and translational) and clinical-epidemiological papers on a wide range of paediatric and adult rh...

Modulating mitochondrial electron flow improves tumor immune response.