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Pearson Lab

@capearson.bsky.social
1.4K followers 1.5K following 57 posts

Developmental Neurobiology | Autism | Epilepsy | Cortex | Neural stem cells | mouse | human Assistant Professor Weill Cornell Medicine. UCLA, University of Sheffield, University of Newcastle upon Tyne alum capearsonlab.com (Posts my own opinions)

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Pearson Lab @capearson.bsky.social · 08/09/2026
Great to see another paper published from our wonderful U54 collaboration! 🧪 congrats Parent lab and team www.frontiersin.org/journals/mol...
frontiersin.org
Frontiers | Cryopreservation of human cortical organoids using vitrification
Vitrification is a fast-cooling cryopreservation technique that limits ice crystal formation and cryoprotectant toxicity. We adapted an established vitrifica...
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Reposted by Pearson Lab
Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 26/08/2026
Excellent talk by @suprajagv.bsky.social at #ISER2026 @iser.bsky.social
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Pearson Lab @capearson.bsky.social · 23/08/2026
Placzek Lab reunion!
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Pearson Lab @capearson.bsky.social · 21/08/2026
Congrats to Momoko and team on their beautiful work making cerebral organoids with anterior and posterior identity 🧠🧪🎉 www.cell.com/cell-stem-ce...
cell.com
Morphogen-guided neocortical organoids with anteroposterior areal identity
Tsai et al. describe a transient morphogen exposure strategy that establishes anterior and posterior organizers in neocortical organoids, driving long-term tissue polarization and areal molecular iden...
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Pearson Lab @capearson.bsky.social · 16/08/2026
Finally refreshed my website thanks to Annette and Isabella in the lab! Hopefully the link works! capearsonlab.com
capearsonlab.com
The Pearson Lab – Developmental biology lab at Weill Cornell Medicine investigating neural progenitor cell biology and neurodevelopmental disorders.
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Pearson Lab @capearson.bsky.social · 05/08/2026
news.weill.cornell.edu/news/2026/08...
news.weill.cornell.edu
Coordinating the Development of Heart Muscle and Vasculature
During development, regional dips in oxygen levels serve as a signal that triggers the coordinated growth of heart muscle and coronary vessels, according to a new study.
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Pearson Lab @capearson.bsky.social · 31/07/2026
Our Summer Scholars Program ended today with a great presentation by this years intern. Congrats to Ritika and everyone involved! appel.weill.cornell.edu/news/congrat...
appel.weill.cornell.edu
Congratulations to Ritika Rohatgi and Dr. Li Fan on the Successful Completion of the 2026 Appel Summer Scholar Program | Helen & Robert Appel Alzheimer’s Disease Research Institute
The Helen & Robert Appel Institute for Alzheimer's Disease Research is proud to congratulate Ritika Rohatgi and Dr. Li Fan on the successful completion of the 2026 Appel Summer Scholar Program.
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Pearson Lab @capearson.bsky.social · 01/07/2026
Usually try to keep posts science-related but phew 😮‍💨 🏴󠁧󠁢󠁥󠁮󠁧󠁿⚽️
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Pearson Lab @capearson.bsky.social · 22/06/2026
Congrats @harrisonlab.bsky.social and team! Another beautiful paper, this time illustrating the role of hypoxia in coordinating coronary angiogenesis and myocardial expansion during zebrafish heart development 🧪♥️🐟 www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Pearson Lab @capearson.bsky.social · 17/06/2026
A lovely study from the Casaccia lab published in Nature Neuroscience showing the importance of glucose metabolism in OPC development 🧠🧪 www.nature.com/articles/s41...
nature.com
Glucose-dependent spatial and temporal modulation of oligodendrocyte progenitor cell proliferation via ACLY-regulated histone acetylation - Nature Neuroscience
The authors identify glucose-derived conversion of citrate to acetyl-CoA upstream of histone acetylation as modulating the regional dynamics of oligodendrocyte progenitors, with extranuclear acetyl-Co...
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Pearson Lab @capearson.bsky.social · 04/06/2026
So excited and honored to join the Stem Cell Reports editorial board as an Early Career Editor. @stemcellreports.bsky.social
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Pearson Lab @capearson.bsky.social · 04/06/2026
As an early career editor for @stemcellreports.bsky.social, I am excited to share that we are looking for submissions in the field of stem cell research! I invite you to submit your work for consideration. invt.io/1bxba2xo5he @isscr.org
invt.io
Check out ISSCR's society journal, Stem Cell Reports!
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Pearson Lab @capearson.bsky.social · 27/05/2026
Forever grateful for the support from the GLUT1 Deficiency foundation and thankful to them for highlighting our research 🧪👩‍🔬🧠 www.g1dfoundation.org/recent-nih-g...
g1dfoundation.org
Recent NIH grants for GLUT1 Deficiency Research | GLUT1 Deficiency Foundation
We are thrilled to share exciting news from the GLUT1 Deficiency research community as two investigators, Dr. Caroline Pearson and Dr. Casey Vickstrom, have recently received NIH funding to support…
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David Solecki @so-lets-kilab70.bsky.social · 05/05/2026
Hey y’all 👋 repost magic appreciated. The Solecki lab is recruiting multiple postdocs at St. Jude for a chromatin imaging project at the edge of live-cell imaging, neuronal cell biology, chromatin regulation, and quantitative image analysis. Ever dreamed of touring chromatin like this? We CAN 🔥
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Pearson Lab @capearson.bsky.social · 20/02/2026
Njoud and I wrote a review article about our favorite cells - radial glia - and their complex yet fascinating relationship with endothelial cells and the cortical vasculature. 🧪🧠 #devbio #neurodev #neuroscience #science Enjoy! www.frontiersin.org/journals/cel...
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Pearson Lab @capearson.bsky.social · 04/02/2026
The Pearson lab is looking for an enthusiastic research technician to join our team! Come join us in New York City! 🍎🧪 jobs.weill.cornell.edu/NY/job/New-Y... #science #neurobiology #devbio
jobs.weill.cornell.edu
Research Technician I
Research Technician I
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Eric Topol @erictopol.bsky.social · 16/01/2026
Tylenol during pregnancy is safe without increased risk of autism, ADHD, or intellectual disability of offspring A new review of the evidence just out www.thelancet.com/journals/lan...
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Pearson Lab @capearson.bsky.social · 09/01/2026
podcasts.apple.com/us/podcast/r...
podcasts.apple.com
Brain Balls
Podcast Episode · Radiolab · 01/09/2026 · 41m
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Pearson Lab @capearson.bsky.social · 29/12/2025
c.org/rjDpX6tzX7
c.org
Support a New York State Biomedical Institute for a Healthier, More Affordable Future
Can you spare a minute to help this campaign?
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Reposted by Pearson Lab
Prasad Jallepalli, MD, PhD @prasad.bsky.social · 09/09/2025
📌
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Pearson Lab @capearson.bsky.social · 07/09/2025
Super proud of Njoud and her PhD thesis work. Here she demonstrates that mitochondrial dysfunction is one of the earliest defects in DRPLA-patient derived neurons. Furthermore, neurodegeneration and ROS accumulation can be rescued with phenylbutyrate treatment. www.biorxiv.org/content/10.1...
biorxiv.org
Mitochondrial dysfunction precedes neurodegeneration in DRPLA patient-derived neurons, and phenylbutyrate improves survival.
Dentatorubral-pallidoluysian atrophy (DRPLA) is a progressive autosomal-dominant neurodegenerative disorder caused by a CAG repeat expansion in the ATN1 gene, which encodes the transcriptional corepre...
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Pearson Lab @capearson.bsky.social · 07/08/2025
Might have to update my website with this image….🧠🧪
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Pearson Lab @capearson.bsky.social · 07/08/2025
Paper submitted! It’s just the beginning but super grateful to all our co-authors🤞🏻🧠⚡️🧪
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Pearson Lab @capearson.bsky.social · 21/06/2025
Enjoyed my time at the @foxp1foundation.bsky.social meeting in the Netherlands. So great to see lots of exciting #FOXP1 related research and meet so many inspiring parents 🦊🧪
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Pearson Lab @capearson.bsky.social · 08/06/2025
Know any great developmental neurobiologists looking for a post doc position? Are you looking for an adventure with cerebral organoids in New York City? We are looking for an enthusiastic new team member! Feel free to DM or email me 🧪 🧠 🍎 #science #neurodev #neurobiology #neuroscience #devbio
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Pearson Lab @capearson.bsky.social · 21/04/2025
Happy to contribute to this methods paper from our collaborators at University of Michigan - it was an exciting day when vitrified cerebral organoids arrived! 🧪 🧠 👩‍🔬 www.biorxiv.org/content/10.1...
biorxiv.org
Cryopreservation of Human Cortical Organoids Using Vitrification
Cryopreservation at ultra-low temperatures is a valuable tool for preserving cells and tissues used in research. However, few protocols exist for the preservation of brain organoid models. Current met...
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Pearson Lab @capearson.bsky.social · 09/04/2025
👏🏻👏🏻👏🏻https://www.cnn.com/2025/04/09/health/nobel-laureate-research-funding-patapoutian/index.html
cnn.com
Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN
Dr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...
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Pearson Lab @capearson.bsky.social · 28/03/2025
#fluorescencefriday 🧪🧠🧫😍 I ❤️ neural stem cells
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Pearson Lab @capearson.bsky.social · 26/03/2025
Can finally breathe and celebrate that my R01 application has been funded! 🧪🧠🥳 #GLUT1 #neurobiology
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Pearson Lab @capearson.bsky.social · 11/03/2025
Excited to see the latest preprint from the Badhuri lab at UCLA 🧠🧫🧪 www.biorxiv.org/content/10.1...
biorxiv.org
Metabolic Atlas of Early Human Cortex Identifies Regulators of Cell Fate Transitions
Characterization of cell type emergence during human cortical development, which enables unique human cognition, has focused primarily on anatomical and transcriptional characterizations. Metabolic pr...
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Pearson Lab @capearson.bsky.social · 08/03/2025
Happy International Women's Day! Science is a team sport and I'm so thankful to be part of such a strong squad of #womeninSTEM @suprajagv.bsky.social @madelineandrews.bsky.social @jennkong.bsky.social @katrinaladams.bsky.social 🧪💪👩‍🔬🦄
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Pearson Lab @capearson.bsky.social · 08/03/2025
Fab new study on #FOXP1 and its role during cortical development from Gena Konopka and her team 🧪🧠🦊👏
cell.com
Cell-type-specific roles of FOXP1 in the excitatory neuronal lineage during early neocortical murine development
Ortiz et al. leverage mice with loss of FOXP1 in their cortical progenitors. Detailed cell-type-specific genomic and epigenetic alterations are described, with key findings in progenitors related to a...
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Reposted by Pearson Lab
Ashley Ingiosi @ashleyingiosi.bsky.social · 02/03/2025
Try this 👇 to access era commons, and view the rest of the thread for access solutions to PubMed, etc.
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Reposted by Pearson Lab
Herman Wong @hermanywong.bsky.social · 11/02/2025
Johns Hopkins officials said the NIH funding cut puts at risk approximately 600 current and ongoing clinical trials at Hopkins, including open clinical trials in cancer, pediatrics and children’s health, heart and vascular studies and the aging brain. www.thebaltimorebanner.com/education/hi...
thebaltimorebanner.com
Johns Hopkins sues federal government over NIH funds
Johns Hopkins University joined several universities in a lawsuit on Monday evening suing the federal government over NIH funding.
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Pearson Lab @capearson.bsky.social · 30/01/2025
New cover slide for work in progress talk tomorrow #devbio #neuroscience 🧪🧠🌈
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Pearson Lab @capearson.bsky.social · 27/01/2025
An actual #microscopymonday in action! Beautiful #organoids packed full of neurons #neurobiology #neurodev 😍🧠🧪
Microscopy image of an organoid on a computer screen
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Pearson Lab @capearson.bsky.social · 10/01/2025
We are hiring! Looking for a research technician to join our team, preferably with some wet lab experience but not necessary. We welcome anyone with a willingness to learn! Applications can be submitted through jobs.weill.cornell.edu/job-invite/9...
jobs.weill.cornell.edu
Research Technician I
Research Technician I
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Pearson Lab @capearson.bsky.social · 29/12/2024
Have some reading to do! Thanks @trayon.bsky.social for this list!
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Pearson Lab @capearson.bsky.social · 11/12/2024
Super happy to receive an R03 from the NIMH to continue our work on FOXP1 and further our understanding of its role during brain development 🧪🧠🦊
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Pearson Lab @capearson.bsky.social · 09/12/2024
So good to be back in LA for this years #AES meeting! And so much exciting science 🧪
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Pearson Lab @capearson.bsky.social · 07/12/2024
Had such a fun morning at UCLA. It was so nice to see old friends and meet new people and have the opportunity to present our work 🧪🧠
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Pearson Lab @capearson.bsky.social · 03/12/2024
#neurojobs
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Pearson Lab @capearson.bsky.social · 01/12/2024
Some post-holiday reading! 😍 🧪 🧠@derubeislab.bsky.social www.biorxiv.org/content/10.1...
biorxiv.org
Sex-specific perturbations of neuronal development caused by mutations in the autism risk gene DDX3X
DDX3X is an X-linked RNA helicases that escapes X chromosome inactivation and is expressed at higher levels in female brains. Mutations in DDX3X are associated with intellectual disability (ID) and au...
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Pearson Lab @capearson.bsky.social · 30/11/2024
Looking forward to visiting #UCLA 🐻 and attending #AES2024 next week….and a trip to Disneyland 😍🏰
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Pearson Lab @capearson.bsky.social · 29/11/2024
Promising study from Zach Grinspan and colleagues for #STXBP1 patients 🧪 www.medrxiv.org/content/10.1...
medrxiv.org
4-Phenylbutyrate for STXBP1 and SLC6A1. Safety, tolerability, seizure, and EEG outcomes. A case series at 2 centers
Introduction Pathogenic mutations in STXBP1 and SLC6A1 can cause developmental delay and epilepsy. 4-phenylbutyrate (4PB), a drug used for urea cycle disorders, rescues dysfunction in pre-clinical mod...
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Pearson Lab @capearson.bsky.social · 28/11/2024
Happy Thanksgiving 🦃
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Reposted by Pearson Lab
Daniel Medina-Cano @danielmedinacano.bsky.social · 22/11/2024
Happy to share our mouse cortical organoid system, which recapitulates in vivo tempos and cell types. We used it to identify gene expression changes across subspecies during development, which might underlie neuroanatomical differences and affect disease penetrance. www.biorxiv.org/content/10.1...
biorxiv.org
A MOUSE ORGANOID PLATFORM FOR MODELING CEREBRAL CORTEX DEVELOPMENT AND CIS-REGULATORY EVOLUTION IN VITRO
Natural selection has shaped the gene regulatory networks that orchestrate the development of the neocortex, leading to diverse neocortical structure and function across mammals, but the molecular and...
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Pearson Lab @capearson.bsky.social · 22/11/2024
#FluorescenceFriday human excitatory neurons CTIP2 in red MAP2 in green and DAPI in blue
human neurons grown in vitro
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Pearson Lab @capearson.bsky.social · 20/11/2024
Do you want to experience Thanksgiving in New York? The Pearson lab is hiring! Research technician and post doc position available
Macy’s Day Parade Turkey float going down Central Park West on Thanksgiving day
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Reposted by Pearson Lab
Harrison Lab @harrisonlab.bsky.social · 19/11/2024
Zebrafish cardiac lymphatics (grey) inching along vegfc (red) expressing coronary arteries. Fun collaboration with the Cao lab published this week 🙌 journals.biologists.com/dev/article/...
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