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Wert Laboratory (PI: Katherine Wert)

@wertlaboratory.bsky.social
1K followers 574 following 252 posts

PI for a group of scientists interested in #Retina #Photoreceptors #StemCells #GeneEditing #InheritedRetinalDystrophies #Ophthalmology at UT Southwestern Medical Center -Posts are my own

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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 21/09/2026
lnkd.in/p/dXDF56-E
lnkd.in
Nafisa Nuzhat and Siqi Tang in the Wert lab are incredible scientists! | Katherine Wert
Nafisa Nuzhat and Siqi Tang in the Wert lab are incredible scientists!
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 18/09/2026
www.linkedin.com/posts/ut-sou...
linkedin.com
#utswophthalmology #visionresearch #retina #utsw | UT Southwestern Ophthalmology
At today's Works-in-Progress Series (WIPS), Tiffany Yee, graduate student researcher in the Wert Lab, presented research investigating how genetic changes can influence the formation of retinal cells ...
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Reposted by Wert Laboratory (PI: Katherine Wert)
Liisa Galea @liisagalea.bsky.social · 09/09/2026
Our new preprint with @ciernialab.bsky.social we investigated transcriptional profiles of microglia (❤️the name) from hAPOEe4/3 female/male mice in HPC &CTX. We saw loads of sex x genotype interactions in both regions Cell cycling, ER stress, lipid metabolism ++ www.biorxiv.org/content/10.6...
biorxiv.org
Sex and APOE Genotype Differentially Shape Microglial Transcriptomic Profiles Across the Hippocampus and Cortex
Female sex and the APOEε4 allele are top risk factors for Alzheimer’s disease (AD). Microglia play a role in the pathogenesis of AD, yet how sex and APOE genotype affect microglia remain poorly unders...
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Reposted by Wert Laboratory (PI: Katherine Wert)
T. Michael Redmond @tmr65.bsky.social · 05/09/2026
Always look up: interior of the Baroque dome of the Cartuja de Ara Christi, a former Carthusian monastery north of Valencia in Spain.
Monochrome image of a circular dome within an arched area. The dome is divided into 8 sectors, each painted with various ornate images such as putti, lions, birds. There is a central dark hole, perhaps beneath a cupola. Surrounding the outside (lower ring) of the dome are 8 windows.
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Reposted by Wert Laboratory (PI: Katherine Wert)
eartha mae @endoeartha.bsky.social · 28/08/2026
Extremely proud to share @acara333.bsky.social and my new paper, out today in @cp-neuron.bsky.social, where we develop a new fluorescent reporter of neural responses to estrogen! 🔬 paper 📝: www.cell.com/neuron/fullt... addgene page 🧬: www.addgene.org/254753/ #neuroskyence 🧪 1/10
graphical abstract of the manuscript depicting pink estrogen-sensitive neurons with a subset of their nuclei colored in green. These green nuclei represent estrogen receptor dependent neural gene transcription, tracked via the expression of a destabilized GFP with a 2 hour half-life. At top, in green is shown a cartoon of the neural response to estrogen across two estrous cycles, and below there is a cartoon of a mouse implanted with an optic fiber for in vivo imaging.
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 28/08/2026
Great way to end #ISER2026, with a Valencian beach sunset and the amazing company of incredible scientists @suprajagv.bsky.social @annaintegrated.bsky.social
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 27/08/2026
UTSW faculty enjoying #ISER2026 @suprajagv.bsky.social
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 27/08/2026
🎉🥳 Thanks, @iser.bsky.social! How about we set up a session on sex differences and sex hormone signaling in the retina for 2028? I’ve seen some incredible scientists at #ISER2026 working in this field
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Reposted by Wert Laboratory (PI: Katherine Wert)
Supraja Varadarajan @suprajagv.bsky.social · 27/08/2026
If you missed these 4 talks by @wertlaboratory.bsky.social @annaintegrated.bsky.social @axonreg2lab.bsky.social and Laura Campello be sure to find them and talk to them about their awesome science! And another plug for the newly minted Campello Lab and Schaeffer Labs. #iser2026 #womeninscience
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 27/08/2026
Some of the beautiful scenery at Cartuja de Ara Christi for the #ISER2026 Gala Dinner.
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Reposted by Wert Laboratory (PI: Katherine Wert)
Levi Todd @levi-todd.bsky.social · 27/08/2026
First paper entirely from our lab is out in the wild! We tested if reprogramming still works in the aged CNS and found the aged retina blocks neurogenesis both intrinsically in Müller glia and through exacerbated inflammation. Then point at some ways to overcome this. www.pnas.org/doi/10.1073/...
pnas.org
Aging limits neuronal regeneration from glia in the mouse retina | PNAS
Reprogramming resident glia into neurons holds great therapeutic promise for neurodegenerative diseases across the central nervous system, yet thes...
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Reposted by Wert Laboratory (PI: Katherine Wert)
ISER @iser.bsky.social · 27/08/2026
It’s @wertlaboratory.bsky.social presenting her work on Altered Retinal Metabolism during Aging and Inherited Retinal Degenerative Disease: Implications for TCA Cycle Modulation
Katherine Wert presenting at the lectern.
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 26/08/2026
Cartuja de Ara Christi supporting pupillary dilation. #ISER2026
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 26/08/2026
Excellent talk by @suprajagv.bsky.social at #ISER2026 @iser.bsky.social
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Dario Tommasini @dariotommasini.bsky.social · 26/08/2026
Excited to share our new paper on the evolution of inhibitory neurons in the retina 👀 now out in Science Advances! www.science.org/doi/10.1126/... Please see my previous post for a brief summary: bsky.app/profile/dari...
science.org
The extreme diversity of retinal amacrine cells has deep evolutionary roots
Amacrine cells (ACs) comprise a heterogeneous class of inhibitory neurons in the vertebrate retina, exhibiting morphological and functional complexity rivaling that of cortical interneurons. Here, we ...
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 25/08/2026
Okay #ISER2026 @iser.bsky.social, representing the cone photoreceptors: blue, green and red opsins. Who wore it better? The @brightfocus.bsky.social WISER dinner cards or the UTSW Ophthalmology faculty?
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 25/08/2026
I’ll be coming home from #ISER2026 with some excellent new office artwork
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 25/08/2026
Great meeting. Can’t wait to see everyone in 2028 and share updates on our data!
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 24/08/2026
Okay, #ISER2026 @iser.bsky.social, I see you. You want to test our cone color perception with the colors you’ve included in the auditorium.
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arvoiovs.bsky.social @arvoiovs.bsky.social · 17/08/2026
Shuyi Chen et al. from Zhongshan Ophthalmic Center find that Ascl1 represses Müller glial and promotes rod photoreceptor fate through repressing notch signaling in late retinal progenitor cells. doi.org/10.1167/iovs.67.10.41
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 15/08/2026
Congratulations to Aashita Doshi, for winning the UT Dallas School of Behavioral and Brain Science SPUR Award for her presentation on our PRDM13 work. She’s been an amazing Green Fellow in the lab these past 6 months and I’m so excited for her future career successes!
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 13/08/2026
Excellent poster presentation yesterday by Nafisa Nuzhat at the Visual System Development GRC. We are grateful for all of the ideas and insights into our findings in retinal development!
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Reposted by Wert Laboratory (PI: Katherine Wert)
preLights @prelights.bsky.social · 13/08/2026
How PRDM family proteins influence neural crest differentiation and craniofacial development. #DevBio Anushka Patil highlights recent work from Lomeli C. Shull et al. @4everbiochemist.bsky.social @artingerlab.bsky.social #preprint #preLight ⬇️ prelights.biologists.com/highlights/p...
prelights.biologists.com
PRDM3 and PRDM16 define cranial neural crest cell states in zebrafish development - preLights
This preprint shows that PRDM3 and PRDM16 are mainly associated with nucleosome-containing chromatin in zebrafish neural crest cells.
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 07/07/2026
A little lab fun www.linkedin.com/posts/utswop...
linkedin.com
#utswophthalmology #ophthalmologylab #retina #utsw | UT Southwestern Ophthalmology
This or that – Wert Lab edition! 🔬 From early birds vs. night owls to making figures vs. writing papers, everyone's got their own style in the lab. Which one are you? 👀 #UTSWOphthalmology #Ophthalm...
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 06/07/2026
I’m excited to share that I’ve taken on a new appointment as Director of Basic Science Research Training for the Department of Ophthalmology. I will help guide & support basic science trainees through mentorship, professional development, & research training initiatives.
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 30/06/2026
www.linkedin.com/posts/ut-sou...
linkedin.com
#utswophthalmology #retina #ophthalmologylab #utsw | UT Southwestern Ophthalmology
What fuels a passion for research? 🔬💡 Members of the Wert Lab recently shared what excites them most about their work – and their answers reflect a deep commitment to discovery and impact. Their res...
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 27/06/2026
I was too busy having the best scientific chats to remember to take a photo, but I had a great time yesterday meeting everyone for the Advance Vision Research of San Antonio seminar hosted by Jason Chen. Special thanks to Daniel Mojica for organizing everything!
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 14/06/2026
Unplanned, but UTSW Ophthalmology basic science female faculty are representing each of the cone photoreceptors at Resident and Alumni Day. Love it!
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 10/06/2026
I have the best team 💕⭐️ www.linkedin.com/posts/ut-sou...
linkedin.com
#utswophthalmology #research | UT Southwestern Ophthalmology
Lab is fun… with them 💙 Behind every breakthrough in ophthalmology research is a team that makes the work meaningful. #UTSWOphthalmology #Research
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 05/06/2026
www.linkedin.com/posts/ut-sou...
linkedin.com
#utswophthalmology #retina #ophthalmology | UT Southwestern Ophthalmology
Allow us to reintroduce the Wert Lab, led by Principal Investigator Katherine Wert! 👋 This incredible group studies the neuronal cells of the retina, particularly the photoreceptor cells, and how the...
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 04/06/2026
Congratulations to recently graduated PhD @emilyrnett.bsky.social on another first-author publication! She found that acute exposure to sucrose or doxycycline during development alters electroretinography in adulthood in 3 different mouse strains. Check it out: www.sciencedirect.com/science/arti...
sciencedirect.com
Acute developmental exposure to doxycycline and sucrose alters retinal function in three commonly used mouse strains
Doxycycline is a widely used tetracycline antibiotic, which has become critical in biomedical research for use with tetracycline-inducible transgenic …
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Reposted by Wert Laboratory (PI: Katherine Wert)
Nature @nature.com · 03/06/2026
Scientists are raising the alarm about a White House proposal that could fundamentally recast federally funded science. The proposed rules would put political appointees in control of all federal grants and de-emphasize peer review, among other measures. go.nature.com/4ucZgsk
go.nature.com
White House proposes vast overhaul of US science funding: what you need to know
The Trump administration’s proposal aims to improve transparency in federal funding, but critics fear the proposed rules would politicize research
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 02/06/2026
Congratulations to Ana and Nafisa for winning travel awards for their excellent poster presentations at the WISMAC Celebration of Women in Science event! 🎉🏆
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 28/05/2026
Ana is giving her final Wert lab meeting on Friday. She’ll show some new data, followed by a full presentation of which Taylor Swift album matches each person in the lab. Anyone want to make guesses on which will be chosen for each member of the Wert lab?? 🎶🎵🎤
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 28/05/2026
Congratulations to Ashley Rowe! 🥳🎉
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 22/05/2026
Congratulations @emilyrnett.bsky.social!
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 21/05/2026
Filmed some Instagram reels for the lab, and learned how old I am. I had absolutely no idea what the “no eating in lab” meant 😂😂 excited to share some fun content soon!
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 21/05/2026
Wert lab outing before Ana, Israa and Emily move on to their next career goals. Bittersweet, but so fun getting all the lab (and two support team members) out for some fun! @emilyrnett.bsky.social
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 16/05/2026
Congratulations to Ashley Rowe for Best Poster Presentation at the annual Organization for the Study of Sex Differences @ossdcomm.bsky.social meeting! #OSSD2026
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BWJones @bwjones.bsky.social · 07/05/2026
It’s Sally Temple giving the closing #ARVO2026 keynote about some of her work in stem cells and AMD therapeutics.
Dr Sally Temple up on stage.
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 06/05/2026
Talented Wert lab scientists! Enjoying the Denver food scene at #ARVO2026 @emilyrnett.bsky.social
Four scientists at a restaurant
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ISER @iser.bsky.social · 06/05/2026
Come by the @iser.bsky.social booth at #ARVO2026 to hear about the next meeting in Valencia, Spain. Soooooo many travel awards to trainees to participate!
The International Society for Eye Research booth with two people sitting at it.
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Reposted by Wert Laboratory (PI: Katherine Wert)
BWJones @bwjones.bsky.social · 05/05/2026
Thank you @michaelfchiang.bsky.social for coming to José-Alain Sahael’s award talk today at #ARVO2026. I am grateful for your calm hand at the head of the NIH/NEI, and your hard work to help vision science move forward.
Drs Michael Chiang and Bryan Jones smiling into the camera.
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Miranda Scalabrino, PhD @icanhasmiranda.bsky.social · 05/05/2026
Great scientists make great friends. #arvo2026 @suprajagv.bsky.social @wertlaboratory.bsky.social
Three young female scientists
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 05/05/2026
Good morning, @arvoinfo.bsky.social! Interested in the gene regulatory networks involved in retinal development? Come hear @emilyrnett.bsky.social talk this morning! #ARVO2026
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 04/05/2026
Good morning, @arvoinfo.bsky.social! Check out these presentations from UTSW today (Monday) #ARVO2026
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 03/05/2026
TODAY (Sunday) come see Tiffany Yee and Ashley Rowe present their research in poster sessions this afternoon! Amazing work with retinal organoids and looking into steroidal sex hormones #ARVO2026 @arvoinfo.bsky.social
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 02/05/2026
Hello @arvoinfo.bsky.social! Excited for this week of science!
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University of Pittsburgh Ophthalmology Department @pittophthalmology.bsky.social · 26/02/2026
From photoreceptors to visual processing — #Webvision is your open-access deep dive into how we see. Now hosted at our Department, continuing its mission to make vision science accessible to all. Start exploring → www.webvision.pitt.edu #Ophthalmology #Neuroscience
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Wert Laboratory (PI: Katherine Wert) @wertlaboratory.bsky.social · 29/04/2026
www.linkedin.com/posts/ut-sou...
linkedin.com
#utswophthalmology #arvo2026 #retina #utsw | UT Southwestern Ophthalmology
We're proud to share that Emily Nettesheim, Ph.D., will be presenting at ARVO 2026 within the retinal cell type development, function, and dysfunction session. Her abstract titled "Acute PRDM13 over...
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