iiinova — where your digital self keeps evolving

Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 23h

📄 New research in @nature.com from IICD affiliate member Dr. Sohrab Shah (@mskcancercenter.bsky.social) and collaborators! The study reveals how cancer cells repair extrachromosomal DNA (ecDNA), identifying a potential target for new cancer therapies. 🔗 www.nature.com/articles/s41...

MMEJ repair of breaks at TA repeats maintains ecDNA and cancer fitness

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 15/10/2026

Thank you to @paulmischel.bsky.social of @stanfordmedicine.bsky.social, for yesterday’s IICD Seminar! 🧬 Dr. Mischel discussed how ecDNA enables cancer cells to rapidly evolve and adapt, shaping our understanding of aggressive cancers. Watch the recording here: youtu.be/ofXvrnCPnd0?...

Paul Mischel discussing with IICD trainees

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 14/10/2026

Only a few spots left for our “Inferring Cancer Clonality Workshop” with @khanhndinh.bsky.social on Oct. 28. See details below to register. ⤵️

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 13/10/2026

👋 Welcome to IICD, Dr. Wilson Gregory! Mentored by @bimidu.bsky.social, Wilson applies machine learning to biological questions, particularly the mechanical interactions of cells during embryonic development.

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 12/10/2026

🧬 New research in @narjournal.bsky.social from IICD members and collaborators introduces Songbird, a computational tool that identifies copy number changes and estimates ploidy in single cells—offering new insights into genomic changes and cancer evolution. Read more > bit.ly/4s4W82y

Figure illustrating Songbird, a flexible genome copy number caller. Figure by Benjamin Wesley, Artwork by Jennifer Jones

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Reposted by Irving Institute for Cancer Dynamics

The Data Science Institute at Columbia University @datascicolumbia.bsky.social · 09/10/2026

DSI Member @brentstockwell.bsky.social has received three new awards to support his innovative research at the intersection of cancer and immunity. Congrats to Prof. Stockwell! Read more via @cancerdynamics.bsky.social: cancerdynamics.columbia.edu/news/new-awa...

cancerdynamics.columbia.edu

New Awards Support Brent Stockwell’s Research at the Intersection of Cancer and Immunity | Columbia University

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 09/10/2026

cc: bimidu.bsky.social, columbiaseas.bsky.social, columbiacancer.bsky.social‬, columbiamed.bsky.social

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 09/10/2026

📢 Join IICD on Oct. 21 at 2 PM ET for a special seminar with Harry Kabodha, co-founder of Varosync! “From Cell States to Patients: Building Cancer Models That Survive Clinical Translation” 📍 Schermerhorn Hall 603 + Zoom 🔗 cancerdynamics.columbia.edu/events/iicd-...

Banner for IICD Special Seminar on October 21 featuring Harry Kabodha

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 08/10/2026

Thank you to Apoorva Singh and @codyslater.bsky.social for presenting at yesterday’s IICD Monthly Research Meeting! 🧬 Apoorva discussed quantifying marginal zone B cell homeostasis across the lifespan, while Cody shared his work on grounding RNA language models in structure and function.

Apoorva Singh, PhD, presents during the October monthly research meeting at IICD.

Cody Slater, PhD, presents during the October monthly research meeting at IICD.

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 07/10/2026

Congratulations to IICD Postdoctoral Research Scientist @lingting-shi.bsky.social on being named a 2026 STAT Wunderkind! 🎉 Lingting uses single-cell and spatial genomics and computational methods to study cancer immunology. 🔗 cancerdynamics.columbia.edu/news/lingtin... #STATWunderkind #Postdoc

STAT Wunderkinds '26 award presented to Dr. Lingting Shi, a Postdoctoral Research Scientist with the IICD.

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 05/10/2026

🏆 Congratulations to IICD member Dr. @brentstockwell.bsky.social on receiving 3 awards supporting innovative approaches to cancer immunology! Read more: 🔗 cancerdynamics.columbia.edu/news/new-awa... cc: @columbiacancer.bsky.social @datascicolumbia.bsky.social

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 02/10/2026

🌟 IICD’s Lorenza Favrot is featured in INet NYC’s Scientists of New York series! Lorenza shares her journey from France to NYC, her transition from the bench to science outreach, and how mentorship, networking, and community have shaped her career. Read more: www.inetnyc.com/blogs.html

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 30/09/2026

cc: stanfordmedicine.bsky.social, paulmischel.bsky.social, @stanford-cancer.bsky.social , stanfordnsurg.bsky.social, columbiacancer.bsky.social‬, columbiamed.bsky.social, jlmcfalinefigueroa.bsky.social��

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 30/09/2026

🧬 Join us Oct. 14 for the IICD Seminar Series! Dr. Paul Mischel of Stanford University presents “Extrachromosomal DNA (ecDNA): Cancer’s Dynamic Circular Genome.” 📅 Oct. 14 | 2 PM ET | Zoom 🔗 cancerdynamics.columbia.edu/events/iicd-...

Banner for IICD Seminar Series on October 14 featuring Dr. Paul Mischel from Stanford University

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 29/09/2026

Congratulations to IICD’s Dr. Sanja Vicković on receiving a three-year grant from the Mathers Foundation! 🎉 Her team will investigate how aging reshapes spatial interactions between the microbiome and host tissues in the colon. 🔗 cancerdynamics.columbia.edu/news/sanja-v...

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 28/09/2026

🧬 Registration is now open for our next From Theory to Practice IICD Workshop! Join @khanhndinh.bsky.social on Oct. 28 for a hands-on workshop on inferring cancer clonality from DNA. Open to Columbia researchers. Limited to 15 participants. Register: cancerdynamics.columbia.edu/events/iicd-...

Graphic for "From Theory to Practice: IICD Workshop Series" on October 28. This workshop's title is "Inferring Cancer Clonality from DNA."

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 25/09/2026

🎉 It’s National Postdoc Appreciation Week! We’re celebrating IICD postdoc @lingting-shi.bsky.social, whose research uses computational approaches to better understand complex biological systems. Meet Linting and learn more about her research: cancerdynamics.columbia.edu/news/postdoc... #NPAW2026

Graphic of Lingting Shi for Postdoc Appreciation Week with the quote: "one of the most exciting moments is when something that initially appears as noise suddenly reveals a clear biological story. It is in these moments that computational modeling and biology truly come together."

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 24/09/2026

🎉 For National Postdoc Appreciation Week, meet IICD postdoc Ren-Yi Wang, PhD! Ren-Yi uses mathematical models to investigate extrachromosomal DNA (ecDNA) dynamics and better understand tumor evolution. #NPAW #postdocs #postdocappreciationweek @columbiacancer.bsky.social

Postdoc Appreciation Week graphic featuring Ren-Yi Wang, PhD with the quote, "The most exciting moments occur when a mathematical model predicts a feature of a biological process that is later confirmed by biological evidence."

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 23/09/2026

🔬 New research from IICD and @columbiamed.bsky.social! Published in @natimmunol.nature.com, the study tracks T-cell clones across time and tissue to reveal how they evolve and contribute to damage in graft-versus-host disease (GVHD). Learn more: cancerdynamics.columbia.edu/news/trackin...

Figure illustrating “Spatiotemporal single-cell profiling reveals T cell clonal dynamics and phenotypic plasticity in human graft-versus-host disease,” including computational methods

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 22/09/2026

🎉 For National Postdoc Appreciation Week, meet IICD postdoc Juliane Schröter, PhD! Juliane uses mathematical and computational approaches to study the immune system, with a particular interest in how immunity develops early in life. Read more: cancerdynamics.columbia.edu/news/postdoc... #NPAW2026

Postdoc appreciation week flyer featuring Juliane Schröter, PhD. A photo of Dr. Schröter with a text bubble containing the text:“Completing my PhD was a major milestone, both professionally and personally. It reinforced that persistence through difficult periods can lead to meaningful success.”

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 21/09/2026

It’s #NationalPostdocAppreciationWeek! 🎉🔬 #NPAW2026 Throughout the week, we’ll be spotlighting IICD postdocs and sharing more about their research, interests, and contributions to our community. Follow along as we celebrate our postdoctoral researchers! 👏

Collage of Postdoctoral Research Scientists at IICD with the text "postdoc appreciate week 2026"

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 18/09/2026

Have you seen Dr. Genevera Allen’s Faces of IICD feature? 🎥 A Professor of Statistics, @zuckermanbrain.bsky.social affiliate, & IICD core member, Dr. Allen develops machine learning and statistical methods to turn complex data into scientific insight. Watch the full feature: youtu.be/ReVQT3MAjuw

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Reposted by Irving Institute for Cancer Dynamics

Lingting Shi @lingting-shi.bsky.social · 17/09/2026

How do T-cell responses evolve across time, state, and tissue space in human GVHD? 🩸🧬📍 In our new @natimmunol.nature.com study @elhamazizi.bsky.social @RanReshef, we build a spatiotemporal atlas and connect clonal dynamics with tissue adaptation and localized injury. 🔗 doi.org/10.1038/s415...

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 17/09/2026

From IICD summer researcher to NSF Graduate Research Fellow! 🎉 Hadassah Mayerfeld is now pursuing an MS/PhD at Columbia under Michael L. Lipton, where she’s developing MRI methods to better understand mild traumatic brain injury. Read about her journey: cancerdynamics.columbia.edu/news/where-r...

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 15/09/2026

New research from IICD’s Kevin Hoffer-Hawlik and @elhamazizi.bsky.social! 📄 Published in Bioinformatics, ARCADIA integrates single-cell RNA sequencing and spatial proteomics to reveal how tissue environments shape cellular states. academic.oup.com/bioinformati...

Screenshot of "ARCADIA reveals spatially dependent transcriptional programs through integration of scRNA-seq and spatial proteomics."

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 14/09/2026

🔬Postdoc Profile: Apoorva Singh, PhD Discover Apoorva's journey from pure mathematics to computational immunology in a new article spotlighting her research and experiences as a postdoctoral researcher at IICD > cancerdynamics.columbia.edu/news/postdoc...

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 11/09/2026

New research from IICD’s Ren-Yi Wang, PhD! 📄 Published in iScience, the study introduces a stochastic framework that uses biological variability to uncover regulatory mechanisms in neural stem cell dynamics Read the paper: bit.ly/3T4u2Hk @columbiacancer.bsky.social @uniheidelberg.bsky.social

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 10/09/2026

Thank you to Dr. Katherine Yudeh King of Baylor College of Medicine for kicking off our 2026–27 IICD Seminar Series yesterday! Dr. King discussed the dynamics of clonal hematopoiesis and how interactions among mutant blood stem cell clones can shape clonal evolution. #CancerResearch

Screenshot of Zoom group discussion with Dr. King

Screenshot of Ren-Yi Wang, a Postdoctoral Research Scientist in the IICD, introducing Dr. King

Screenshot of Dr. King presenting in the September Seminar

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 09/09/2026

Welcome to IICD, Haochen Yang, in the @bimidu.bsky.social! 🎉 A PhD student in Biomedical Informatics in the Dumitrascu group, Haochen develops and applies computational methods to study developmental biology and cancer progression.

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 08/09/2026

What can two twentieth-century mathematicians teach us about collaboration in modern cancer research? Simon Tavaré revisits the wonderfully unconventional Hardy-Littlewood Axioms—and asks what they can still teach us today. Read here: cancerdynamics.columbia.edu/news/how-col...

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 04/09/2026

Welcome to IICD, James Lee! 🎉 A @apammsecu.bsky.social student in the Vicković Lab at the @nygenome.org, James develops genetic perturbation approaches for intact tissue to study how cellular neighborhoods influence perturbation effects in diseases including cancer.

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 03/09/2026

Yesterday, IICD kicked off its fall Monthly Research Meetings! 🔬 Kamila Szumala discussed cellular programs associated with T-ALL relapse, while Marek Kampa shared research on using dynamically guided representation learning to infer B-cell developmental trajectories.

Marek Kampa presents at IICD Monthly Research meeting

Kamila Szuzmala presents at IICD Monthly Research Meeting

Catered lunch from Fumo at IICD September monthly Research Meeting

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