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Canals Lab

@canalslab.bsky.social
1K followers 273 following 50 posts

Neuroscience, memory, addiction, brain imaging, translational research

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Canals Lab @canalslab.bsky.social · 30/09/2026
Congratulations to all the team! Equilibrium between flexibility and stability of memories under the control of PV cells in the dentate gyrus!
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Augusto ER @augustoer.bsky.social · 06/08/2026
🚨URGENT 🚨 Looking for candidates for a postdoctoral contract at @neuroalc.bsky.social to join me in deciphering the neural circuits controlling chronic itch diseases!! Deadline very soon, start date October 1st 2026!! Please spread the word! #NeuroJobs
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 02/09/2026
Lamentamos profundamente el fallecimiento del Prof. Constantino Sotelo, referente de la neurociencia española. Primer director de la Cátedra de Neurobiología Remedios Caro Almela, dejó huella en el @neuroalc.bsky.social. Nuestras condolencias a sus familiares, amigos y colaboradores #DEP
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PessoaBrain @pessoabrain.bsky.social · 28/07/2026
𝗡𝗲𝘂𝗿𝗮𝗹 𝘁𝗿𝗮𝘃𝗲𝗹𝗶𝗻𝗴 𝘄𝗮𝘃𝗲𝘀 𝗶𝗻 𝗰𝗼𝗿𝘁𝗲𝘅: 𝗡𝗲𝘁𝘄𝗼𝗿𝗸 𝗺𝗲𝗰𝗵𝗮𝗻𝗶𝘀𝗺𝘀 𝗮𝗻𝗱 𝗽𝗼𝘁𝗲𝗻𝘁𝗶𝗮𝗹 𝗿𝗼𝗹𝗲𝘀 𝗶𝗻 𝗻𝗲𝘂𝗿𝗮𝗹 𝗰𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻 A must read for systems neuroscience. #neuroskyence doi.org/10.1016/j.ne...
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PLOS Biology @plosbiology.org · 28/07/2026
How do #learning processes related to reward exploitation and exploration interact with one another in the brain? This study uses behavior, neuroimaging, pharmacology, and modeling to reveal shared learning mechanisms, connecting with individual traits and experiences 🧪#AcademicSky plos.io/4fDkj27
Relationship between reward-learning interference and exploration-associated neural responses. The images show brain models on the left with regions of differential activity highlighted. Graphs on the right show significant correlations between neural activity patterns and behavior.

Using general linear model (GLM) 2 (see Materials and methods), dorsomedial prefrontal cortex (dmPFC) exhibited significant activations during exploration (contrast “Exploration> Exploitation”). Activated clusters were corrected for multiple comparisons at the whole-brain level (cluster-forming threshold of p < 0.001, and a cluster-level familywise error rate of p < 0.05). The color bar shows SPM-derived t scores. See S5 Table for details. Based on GLM3 (see Materials and methods), the BOLD signal extracted from the suprathreshold dmPFC clusters significantly covaried with the reduction in correct rates in reward-learning interference (RLINT) vs. reward-learning control (RLCON) trials.
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Nature Reviews Neuroscience @natrevneuro.nature.com · 27/07/2026
Brain mitochondria as key drivers of cognition and behaviour — a Review by Carmen Sandi, Mary Kay Lobo, Fiona Hollis, Yusuke Hirabayashi, Jaime de Juan-Sanz & Juan P. Bolaños #neuroscience #neuroskyence www.nature.com/articles/s41...
nature.com
Brain mitochondria as key drivers of cognition and behaviour - Nature Reviews Neuroscience
Neuronal and glial mitochondria support neuronal circuit function and plasticity through the supply of energetic substrates and the regulation of cellular physiology. Sandi and colleagues describe how...
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Nature Reviews Neuroscience @natrevneuro.nature.com · 27/07/2026
Microglial states revisited: from homeostasis to disease — a Review by Bart J. L. Eggen & Susanne M. Kooistra #neuroscience #neuroskyence www.nature.com/articles/s41...
nature.com
Microglial states revisited: from homeostasis to disease - Nature Reviews Neuroscience
Transcriptomic microglial states are shaped by development, ageing, genetics, environment and disease. In this Review, Eggen and Kooistra discuss how the formation of so-called hidden immune-memory st...
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 12/06/2026
📢 Fully funded PhD position available! Join @maxeggl.bsky.social team at @desantislab.bsky.social to develop mathematical and computational approaches for understanding brain health and disease through AI-inspired biomarkers of brain structure and function. More info ⬇️ in.umh-csic.es/es/ofertas/m...
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 30/06/2026
🎉 ¡Enhorabuena a @nietoangela.bsky.social, @bertalsl.bsky.social y Katia Sofía Illescas (@borrell-lab.bsky.social) por las ayudas de @contracancerinv.bsky.social para impulsar sus proyectos de investigación! Gracias por seguir apoyando la investigación oncológica👏 in.umh-csic.es/es/el-instit...
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 01/07/2026
☀️ ¡Bienvenido, julio! Empezamos este caluroso mes viajando al corazón de la memoria con la imagen 'Flying Memory', de Mirjam Cangonja (@barcolab.bsky.social)🧠✨ #SciencePhoto_IN @csic.es @dicv.csic.es @umh.es
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 15/06/2026
We hosted our 19th IN Progress Report Workshop🙌 @pastorparejalab.bsky.social, @jplopez-atalaya.bsky.social, I. Del Pino, @reiglab.bsky.social, A. Kardamakis, J.A. Moreno Bravo, S. Jurado, I. Pérez-0taño, @neuroviana.bsky.social, J. Sáez Valero & @desantislab.bsky.social presented their findings 🔝
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 29/05/2026
🧠 Ayer arrancó ‘Neurociencia sin barreras’, iniciativa del @neuroalc.bsky.social para acercar la neurociencia a públicos diversos mediante actividades accesibles y participativas. La primera jornada se celebró con beneficiarios de la Fundación Adecco👇 in.umh-csic.es/es/el-in-umh... @csic.es @umh.es
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 26/05/2026
El 6 de junio tienes una cita en la #FeriaLibroMadrid con los investigadores Santiago Canals @canalslab.bsky.social y Daniel Lloret @umh.es. De 12:30 a 13:30 firmarán su libro 'Juego de apuestas y publicidad. Salud, impacto social y prevención'. @csicdivulga.bsky.social @editorialcsic.bsky.social
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 27/03/2026
Today, we had the pleasure of hosting Dr. Riccardo Marioni from @uoe-igc.bsky.social at our #SeminarsIN with his talk: “Tracking brain health from saliva and blood samples”. A fantastic lecture, thank you! 👏👏 @csic.es @dicv.csic.es @umh.es
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 20/03/2026
🧠 Alicante hosted the 1st Systems-IN-Action Meeting, bringing together international experts to explore how brain circuits drive behavior, from sensation to action. A key step forward in systems neuroscience and scientific collaboration. Read more👇 in.umh-csic.es/en/alicante-... @csic.es @umh.es
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 17/03/2026
🔬 Juana Gallar, Director of the @neuroalc.bsky.social and @theneurotecheu.bsky.social lead at @umh.es, took part in a discussion on how female leadership is shaping the future of neurotechnology, science, and society. More info 👇 neurotecheu.umh.es/en/2026/03/1... #WomenInScience #NeurotechEU #8M
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 10/02/2026
👩‍🔬 Un año más el @neuroalc.bsky.social celebra el Día Internacional de la Mujer y la Niña en la Ciencia #11F Varias investigadoras acudirán a centros educativos para acercar la ciencia a las aulas. 📣 Sigue nuestras redes 👉 in.umh-csic.es/es/dia-inter... #TodasHacemosCiencia #WinS #MujeryCiencia
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 06/02/2026
🎉 Enhorabuena al recién nombrado Dr. Antonio Cerdán Cerdá por su defensa de #TesisIN y felicitaciones a sus directores de Tesis, los Dres. Silvia De Santis @desantislab.bsky.social y Santiago Canals @canalslab.bsky.social 🎉 @csic.es @dicv.csic.es @umh.es
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 09/01/2026
The @neuroalc.bsky.social invites applications for two permanent research positions (Científico titular @csic.es , Tenure-track) to build independent programs in a collaborative, international environment. We welcome applicants from all demographic backgrounds 👇 in.umh-csic.es/en/ofertas/d...
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 25/11/2025
🚨 Registration open for the 1st Systems-IN-Action neuroscience meeting on Circuits, Systems, Behaviour, and Computation at the @neuroalc.bsky.social in Alicante (Spain) Deadline: Jan 15 or until 120 participants! Orgs: @kardamakis.bsky.social, Ramón Reig & Isabel Pérez Otaño systems-in-action.umh.es
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 10/12/2025
We’re gearing up for our XXII Christmas Meeting! 🎄✨ Check out the full program and join the holiday spirit 👀🎁 #ChristmasMeeting_IN @csic.es @dicv.csic.es @umh.es @leroyfelix.bsky.social @kardamakis.bsky.social
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Canals Lab @canalslab.bsky.social · 22/11/2025
Congratulations!!!
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 19/11/2025
El investigador Santiago Canals @canalslab.bsky.social ha colaborado con la #OficinaC del Congreso en la elaboración del informe ‘Menores y redes sociales’ 🧠💻 Más info 👇 in.umh-csic.es/es/el-invest... #RedesSociales #SaludMental #CSIC #Tecnología @csic.es @dicv.csic.es @umh.es
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Canals Lab @canalslab.bsky.social · 08/10/2025
Thank you Aldo! We learnt that a triplet isn’t just jazz, it can set the hidden rhythm of a neuronal ensemble!
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 03/10/2025
Today we had the pleasure of hosting Dr. Aldo Genovesio from @uniupo.bsky.social at our #SeminarsIN with his talk: “What do we learn by shifting focus from neurons to neuronal assemblies?” A fantastic lecture, thank you! 👏👏 @csic.es @dicv.csic.es @umh.es
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Canals Lab @canalslab.bsky.social · 26/09/2025
Inspiring work. Thank you Jaime!
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Julián Macías @julianmacias.bsky.social · 19/09/2025
Israel ha detenido al director de orquesta israelí Ilan Volkov después de condenar las acciones de su país en Gaza durante un concierto en Londres. “Detengan el genocidio. Lo está destrozando todo. Párenlo ya”.
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 16/09/2025
🔥New study published in PLoS Computational Biology, led by Santiago Canals @canalslab.bsky.social at @neuroalc.bsky.social and @claudiomirasso.bsky.social at @ifisc.uib-csic.es , reveals how brain rhythms flexibly route information. More info 👇 in.umh-csic.es/en/articulos...
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 11/07/2025
Huge thanks to: 🔹 David Moratal - @upv.es 🔹 @plopezlarrubia.bsky.social - @iibm-csic-uam.bsky.social 🔹 Mohamed Selim - @uniofnottingham.bsky.social 🔹 From @neuroalc.bsky.social: Santiago Canals @canalslab.bsky.social, Silvia De Santis @desantislab.bsky.social & @maxeggl.bsky.social 🙌
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Pilar López Larrubia @plopezlarrubia.bsky.social · 09/07/2025
Happy to join the 2nd NeurotechEU Summer School on Preclinical Magnetic Resonance Imaging and Spectroscopy, presenting on #MetabolomicNMR in beautiful #Alicante!
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 04/07/2025
🎉 Today we celebrated the 18th IN Progress Report Workshop at @neuroalc.bsky.social! Leaders from 7 of our 8 scientific programs shared their latest research, alongside posters by our 2nd-year PhD students. Here's a quick recap 🧵👇 #Neuroscience #jornadasIN2025 @csic.es @dicv.csic.es @umh.es
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Eloísa del Pino @eloisadelpino.bsky.social · 14/06/2025
elpais.com/internaciona...
elpais.com
La junta de las becas Fulbright dimite en pleno por la interferencia del Gobierno de Trump
“Inyectar política y mandatos ideológicos en el programa viola la letra y el espíritu de la ley”, denuncian sus miembros
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Canals Lab @canalslab.bsky.social · 10/06/2025
👏🏻👏🏻
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Jonathan Portes @jdportes.bsky.social · 08/06/2025
Jeremy Bowen's long, measured, objective, but ultimately entirely clear and conclusive essay on Israeli war crimes. As Jonathan Sumption puts it: "These things make genocide the most plausible explanation for what is now happening." www.bbc.co.uk/news/article...
bbc.co.uk
Israel is accused of the gravest war crimes in Gaza
Distinguished lawyers, senior humanitarians and diplomats tell Jeremy Bowen why they are increasingly concerned about the catastrophe inside Gaza
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Ketan Joshi @ketanjoshi.co · 26/05/2025
hey lovelies, I finally got around to publicly sharing my compilation of big tech energy and emissions data. I'll be using it in articles, posts etc but it's yours too, free to use (w/ attribution is nice) ketanjoshi.co/2025/05/23/d...
a chart showing power consumption of big tech companies
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Canals Lab @canalslab.bsky.social · 27/05/2025
Thank you to all collaborators @wetuad.bsky.social @claudiomirasso.bsky.social @neuroalc.bsky.social @csic.es @umh.es @ifisc.uib-csic.es #Neuroscience #Memory #DBS #CognitiveFlexibility #Neuroimaging #NeuroTech
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Canals Lab @canalslab.bsky.social · 27/05/2025
If you are interested, find the full article here: rdcu.be/enT5X
rdcu.be
NAc-DBS selectively enhances memory updating without effect on retrieval
Neuropsychopharmacology - NAc-DBS selectively enhances memory updating without effect on retrieval
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Canals Lab @canalslab.bsky.social · 27/05/2025
Methodological highlight: We developed a novel spatial task that dissociates encoding vs. retrieval within-subjects using a high-dimensional behavioral readout. Standard memory tests might have missed this.
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Canals Lab @canalslab.bsky.social · 27/05/2025
Why does this matter? Memory flexibility is key in psychiatric disorders characterized by cognitive rigidity. Our study provides a mechanistic foundation for using NAc-DBS to improve cognitive flexibility.
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Canals Lab @canalslab.bsky.social · 27/05/2025
fMRI revealed that NAc-DBS activates a broad memory-related brain network: septum, entorhinal & insular cortices—with some degree of adaptation but not desensitization over time. We propose it mimics a dopaminergic “novelty” signal, reinforcing the encoding of new information.
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Canals Lab @canalslab.bsky.social · 27/05/2025
Using high-resolution behavioral analysis & fMRI in rats, we dissected memory into short-term, long-term, encoding, and retrieval. 📌 Key finding: NAc-DBS enhances the encoding of new long-term memories—not short-term memory or recall.
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Canals Lab @canalslab.bsky.social · 27/05/2025
Why NAc-DBS? NAc-DBS is already used to treat psychiatric conditions like OCD and depression. But it could also boost memory. We designed a new spatial navigation task to find out.
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Canals Lab @canalslab.bsky.social · 27/05/2025
New Study Out Now! We investigated how deep brain stimulation (DBS) of the nucleus accumbens (NAc) affects memory. www.nature.com/npp/ Title: NAc-DBS selectively enhances memory updating without effect on retrieval 👇 THREAD 👇
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Borrell Lab @borrell-lab.bsky.social · 16/05/2025
It was a real treat to host @franzelab.bsky.social. Such exciting and thought provoking findings!! Thanks for your visit 👏🏻👏🏻
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 08/05/2025
Mañana, en la jornada 'El juego de apuestas: un problema de salud pública', se presentará el libro 'Juego de apuestas y publicidad', coordinado por Santiago Canals @canalslab.bsky.social y Daniel Lloret @umh.es . Una obra clave para entender el impacto de la publicidad en el juego📚 @csic.es
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 05/03/2025
El @neuroalc.bsky.social y la Cátedra de Neurobiología Remedios Caro Almela organizan la mesa redonda del Ciclo Cerebro y Sociedad 'El arte de entender el cerebro: Cajal y las Neurociencias🧠 Sesión abierta a todos los públicos‼️ #SemanaCerebroIN Os esperamos en el Club Información #Alicante
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Canals Lab @canalslab.bsky.social · 08/03/2025
Today we celebrate #InternationalWomensDay. A privilege to work in a research center with such amazing colleagues!
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Liset M. de la Prida @lmprida.bsky.social · 26/02/2025
New from the lab!! 👉🏼 authors.elsevier.com/a/1kgT43BtfH... 📝 @cellpress.bsky.social We discovered that genetically-defined neuron types in the hippocampus form unique manifolds! Dual color imaging, chemogenetics and topological analysis all at once! With Juan Gallego @juangallego.bsky.social
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Instituto de Neurociencias CSIC-UMH @neuroalc.bsky.social · 07/03/2025
Today, Dr. Javier Fernández-Martínez from Instituto Biofisika UPV/EHU - CSIC offered us a fantastic #SeminarsIN about the structural and functional mapping of the nuclear pore complex. Great talk, thank you! 👏👏 @csic.es @umh.es @morantelab.bsky.social
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Canals Lab @canalslab.bsky.social · 06/03/2025
Great work by López-Bendito Lab on sensory cortex reorganization. Congratulations to the team!
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