Nitrogen-fixing Nostoc species form symbiotic relationships with diverse plants, yet the role of specialized metabolites in these interactions remains poorly understood. Here, we identify a previously...

Scientists made 16 successful viruses that had their genetic code designed by artificial intelligence.

Cellular membranes are essentially complex and heterogeneous assemblies. The lipid bilayer forms the basis of the membrane architecture, and the assoc…

The lipase LipA from Pseudomonas aeruginosa is an extracellular enzyme that plays an important role in bacterial infections. Prior to its export via the type II secretion system, LipA requires the cog...

The Sec translocon and the YidC/Oxa1-type insertases universally mediate biogenesis of α-helical membrane proteins, but the molecular basis of their cooperation has remained disputed. Recent discovery...

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Structure of a stalled E. coli 70S RNC-NuoK-86 in complex with the membrane protein insertase SecYEG-YidC

We are looking for a candidate to undertake a PhD on extracellular electron exchange between photosynthetic and non-photosynthetic microorganisms, focusing on underlying molecular mechanisms and regul...

We are seeking a Postdoctoral Researcher to investigate extracellular electron uptake in photosynthetic bacteria (cyanobacteria), focusing on underlying molecular mechanisms and regulation, and with c...

A previously non-annotated, CO2-controlled gene was identified in the cyanobacterium Synechocystis sp. PCC 6803 that encodes a small protein contributing t

Operons are gene clusters controlled by a single promoter that enable coordinated translation from a single mRNA. Here we describe an expansion of the CyanoGate MoClo toolkit to assemble synthetic ope...

Three new synthetic algal culture media are described that have been used to cultivate ~12,000 diverse strains of (micro)algae, one culture medium for marine and brackish-water algae (ASP-MEL (Artific...

In many algae, photosynthesis is boosted by biophysical CO2-concentrating mechanisms, which pack the CO2-fixing enzyme Rubisco into liquid-like organelles called pyrenoids. Engineering C3 crops with a...

Microbial communities play a key role in biogeochemical transformations in a wide range of ecosystems, but they also hold significant potential to enh…

Fang et al. reveal how a bacterial circadian clock turns genes on and off at the right times of day and use the purified proteins to drive circadian gene transcription in a test tube for days.

Author summary Type IV pili enable Pseudomonas aeruginosa to attach to surfaces, move (twitch), and form biofilms. Pilus extension is powered by the motor protein PilB, which is regulated by other fac...

imageimageChemotaxis receptors typically mediate biased movement of motile bacteria in environmental gradients by controlling rotation of the flagellar motor. This study identifies a chemotaxis recept...

Prochlorococcus is the most numerically abundant photosynthetic organism in the oceans and plays a role in global carbon cycling. Despite its ecological significance and the availability of over a tho...

Nature Communications - RNA-binding proteins play key roles in post-transcriptional gene regulation. Here, Hemm et al. developed RAPDOR, a widely applicable tool based on Jensen-Shannon Distance...

Single-pot solid phase-enhanced sample preparation (SP3) and trifluoroacetic acid workflows open the door to high-throughput quantitative proteomics in cya

Circadian clocks allow organisms to anticipate daily fluctuations in light and temperature, but how this anticipatory role promotes adaptation to d...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Abstract. Pigments and dyes are widely used in multiple industries. Ketocarotenoids are a highly sought-after group of pigments with a dark-red hue and str

npj Biological Timing and Sleep - The cyanobacterial circadian clock

The advent of oxygenic photosynthesis by ancient cyanobacteria approximately 2.4 billion years ago profoundly transformed Earth’s landscape. Today, cyanobacteria inhabit a vast array of aquatic habita...