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Bita Moghaddam

@bita137.bsky.social
8.2K followers 597 following 1.7K posts

Ketamine Karen, Dopamine Dame Here via Tehran/KU/Yale/Pitt author of KETAMINE mitpress.mit.edu/9780262542241 and a lot of good papers scholar.google.com/citations?user=W…

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Bita Moghaddam @bita137.bsky.social · 10h
I learned my lesson a few years ago and never get them together after that 🥵🤒- giving a week between each shot makes a big difference, at least for me
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Bita Moghaddam @bita137.bsky.social · 11h
Congrats and about time!! Thank you for always being a kind and approachable colleague
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Mark Histed @markhisted.org · 19h
Nobel Prize awarded for optogenetics. Congrats to Karl Deisseroth, Hegemann, and Nagel. The prize is well-deserved, for work that has been transformative. a few quick thoughts 1/4 🧪#neuroscience
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Bita Moghaddam @bita137.bsky.social · 15h
Nice review AND we have actual data to support (or refute!) some of the theories here on how psychedelics may influence reward learning and behavioral flexibility www.biorxiv.org/content/10.6...
biorxiv.org
Psilocybin asymmetrically modulates outcome-based choice and cortical processing under uncertainty
Emerging clinical research with psilocybin highlights the value of the psychedelic experience on successful treatment of a multitude of psychiatric disorders. While the psychedelic trip or clinical su...
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Bita Moghaddam @bita137.bsky.social · 15h
This is a really nice review! And we have actual data in support of some of your prediction looking at the effect of psilocybin on the exact task shown on Figure 3 www.biorxiv.org/content/10.6...
biorxiv.org
Psilocybin asymmetrically modulates outcome-based choice and cortical processing under uncertainty
Emerging clinical research with psilocybin highlights the value of the psychedelic experience on successful treatment of a multitude of psychiatric disorders. While the psychedelic trip or clinical su...
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Bita Moghaddam @bita137.bsky.social · 01/10/2026
Nice to see this out finally! Congrats
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Bita Moghaddam @bita137.bsky.social · 01/10/2026
Does double jeopardy protection apply here?
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Bita Moghaddam @bita137.bsky.social · 30/09/2026
Nice! you must feel great 😊
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Bita Moghaddam @bita137.bsky.social · 30/09/2026
yep. and the staging approach is not theoretically new but we finally have tools to begin to come of with treatment options that are stage-specific
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Bita Moghaddam @bita137.bsky.social · 30/09/2026
And I was not just theorizing: the ideas are supported by several recent preclinical papers including this from the lab www.nature.com/articles/s41...
nature.com
Grin2a knockout in adolescent dopamine neurons disrupts prediction error signaling and produces a phenotype relevant to schizophrenia - Molecular Psychiatry
Molecular Psychiatry - Grin2a knockout in adolescent dopamine neurons disrupts prediction error signaling and produces a phenotype relevant to schizophrenia
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Bita Moghaddam @bita137.bsky.social · 30/09/2026
Please check out my futuristic opinion piece in @jamapsychiatry.com "specific treatments for schizophrenia that are tailored to target symptoms at different developmental stages are no longer the stuff of science fiction, but instead are realistic future goals" jamanetwork.com/journals/jam...
jamanetwork.com
Updating Treatment Goals for Schizophrenia
This article discusses research providing renewed reasons to revisit the utility of glutamatergic drugs for treating schizophrenia.
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Bita Moghaddam @bita137.bsky.social · 29/09/2026
uncanny resemblance of phraseology uses with this paper www.nature.com/articles/s41...
nature.com
Interacting spiral wave patterns underlie complex brain dynamics and are related to cognitive processing - Nature Human Behaviour
Using concepts mostly familiar to fluid physicists, the authors manage to elegantly tackle the complex problem of describing large-scale brain activity patterns, providing a rich foundation for the fu...
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Yohan J John @dryohanjohn.bsky.social · 28/09/2026
Reading a review on serotonin by Peter Dayan and Quentin J.M. Huys from 2009. It's an increasingly rare experience in this LLM-blighted era to read a paper with good prose.
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Bita Moghaddam @bita137.bsky.social · 25/09/2026
Treat it like preparing a meal for guests - people remember the first and the last (hors d'oeuvres and dessert) course better than the meal itself. So have solid intro and conclusion slides and don't worry about too much data in the middle
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Mark Baxter 🏳️‍🌈🧂 @markgbaxter.bsky.social · 24/09/2026
If you work with international personnel, you may want to comment on this proposed rule change that would put visa holders out of status immediately (instead of after a 60 day grace period) when their employment ends keepthe60days.com
keepthe60days.com
Keep the 60 Days: H-1B, E-3, L-1, O-1 & TN grace period
DHS proposes ending the 60-day grace period after a layoff for H-1B, E-3, L-1, O-1 and TN visa holders. Comment on USCIS-2026-0364 before November 10, 2026.
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Bita Moghaddam @bita137.bsky.social · 24/09/2026
static.klipy.com
Vintage Typewriter in Use
ALT: Vintage Typewriter in Use
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Bita Moghaddam @bita137.bsky.social · 23/09/2026
I am thoroughly impressed. I thought the tools in my lab are well organized but this is the next level
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Bita Moghaddam @bita137.bsky.social · 23/09/2026
Leaves are turning already. Winter is coming 😕
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Bita Moghaddam @bita137.bsky.social · 23/09/2026
destruction of creative thinking by 1) professional editors who take 3+ years to accept a paper asking for more & more data (yes reviewers ask for it but editors used to stop it) and 2) uni hiring committees who only interview young people with a massive dataset paper that their PI pushed for
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Will Giardino @willgiardino.bsky.social · 05/09/2026
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Bita Moghaddam @bita137.bsky.social · 05/09/2026
😂
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Bita Moghaddam @bita137.bsky.social · 04/09/2026
“If men could get pregnant, abortion would be a sacrament” Gloria Steinem
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Bita Moghaddam @bita137.bsky.social · 04/09/2026
I hope you at least get some raw milk during the coffee break
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Bita Moghaddam @bita137.bsky.social · 04/09/2026
It should not have mattered even if you were married to a billionaire. What your partner or parents make should not even enter the discussion/negotiation
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Bita Moghaddam @bita137.bsky.social · 04/09/2026
static.klipy.com
Is That Legal Stan Marsh
ALT: Is That Legal Stan Marsh
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Bita Moghaddam @bita137.bsky.social · 04/09/2026
and not in my current institution - this happened in the early 90s and how it "used to be"
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Bita Moghaddam @bita137.bsky.social · 04/09/2026
For my first academic position, I politely voiced concern that my salary was too low. I was told that your husband works too so the combined salaries should be considerable
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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 04/09/2026
I went to Columbia for undergrad in 1991. It had only begun admitting women 4 years earlier, in 1987
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Matthew Baggott @mattbagg.eurosky.social · 03/09/2026
This is a genuinely exciting (mouse) result that may address a big unmet need and seemingly works with non psychedelic 2A agonists (tabernanthalog worked). www.science.org/doi/10.1126/...
science.org
Psilocybin prevents chemotherapy-induced peripheral neuropathy through mitochondrial trafficking preservation
Chemotherapy-induced peripheral neuropathy (CIPN) is a disabling, often irreversible toxicity that affects millions of patients, limits life-saving cancer therapy, and lacks proven treatment. In this ...
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Michael Hobbes @michaelhobbes.bsky.social · 03/09/2026
I’m sorry but this is never going to stop being funny
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Bita Moghaddam @bita137.bsky.social · 03/09/2026
In mice? I don’t know
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Bita Moghaddam @bita137.bsky.social · 03/09/2026
THC (CB1 receptor stimulation) does activate BDNF via mTORC1 signaling but BDNF, currently the darling of the neuroplastigen field, is a ubiquitous molecule and activated by just about any drug experience (antipsychotics, chronic nicotine, etc)
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Ann Powers @annkpowers.bsky.social · 03/09/2026
All the mothers are going
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Samantha Butler @samanthabutler.bsky.social · 02/09/2026
Please spread the news - the Department of Neurobiology at UCLA is hiring. This is an open rank search for all and any amazing neuroscientists! Please apply here by Nov 15th, first review end of October : recruit.apo.ucla.edu/JPF11296
recruit.apo.ucla.edu
Open-rank tenure-track faculty position
University of California, Los Angeles is hiring. Apply now!
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Erin Rich @erinlrich.bsky.social · 02/09/2026
Hey, we’ve been studying mnemonic chunking in🐒! With @fkchiang89.bsky.social Here’s the rundown: 🧵 www.cell.com/current-biol...
cell.com
Compression as a neural mechanism of mnemonic chunking in prefrontal cortex
Chiang and Rich show that macaques spontaneously chunk spatial targets in a self-ordered working memory task. dlPFC neurons compress chunked targets into lower-dimensional representations that are shi...
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Bita Moghaddam @bita137.bsky.social · 01/09/2026
to be clear, I am all for #celebrating if not #bragging about PI and trainee wins, here, on LinkedIn and even on xwitter. My issue is with lack of genuine or useful information exchange
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Jeremy Hogeveen @jeremyhogeveen.bsky.social · 01/09/2026
We ( @vincentcostaphd.bsky.social and I ) wrote a "Hot Topics" piece for @npp-journal.bsky.social on the potential utility of frontopolar cortex TMS in precision psychiatry. Relevant now that this region has been accessed in some excellent recent NHP studies. www.nature.com/articles/s41...
nature.com
Translating macaque frontopolar cortex discoveries into psychiatric treatments - Neuropsychopharmacology
Neuropsychopharmacology - Translating macaque frontopolar cortex discoveries into psychiatric treatments
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Bita Moghaddam @bita137.bsky.social · 01/09/2026
#proud of you and superkash.bsky.social
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Bita Moghaddam @bita137.bsky.social · 01/09/2026
perfectly phrased! thank you
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Bita Moghaddam @bita137.bsky.social · 01/09/2026
despite #icky experimental design, I am #thrilled the data is now out after 5 #glorious years of #delightful back and forth with the #brilliant journal editors
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Bita Moghaddam @bita137.bsky.social · 01/09/2026
#overjoyed #beyondexcited
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Bita Moghaddam @bita137.bsky.social · 01/09/2026
I honestly see very little actual "discussion" about data even related to mundane safe questions.
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Bita Moghaddam @bita137.bsky.social · 01/09/2026
🤔
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Bita Moghaddam @bita137.bsky.social · 01/09/2026
I know many scientists love Linkedin and are very active on it but I find it boring if not uninformative - my feed is 90% folks posting their latest awards or papers and others liking it 👏and/or replying congrats. No meaningful comments, no humor, no sarcasm, no disagreement What am I missing?
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Bita Moghaddam @bita137.bsky.social · 01/09/2026
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Bita Moghaddam @bita137.bsky.social · 01/09/2026
early 80s were truly the greatest years for movies
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Bita Moghaddam @bita137.bsky.social · 01/09/2026
static.klipy.com
Blade Runner Japan: Futuristic Cityscape
ALT: Blade Runner Japan: Futuristic Cityscape
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Alex Kwan @alexkwan.bsky.social · 31/08/2026
Two large-scale electrophysiologyical studies of psilocybin's effects in mice, from @alleninstitute.org @torbenott.bsky.social and others. Should be a treasure trove of data for those interested in perceptual effects of #psychedelics www.biorxiv.org/content/10.6... www.biorxiv.org/content/10.6...
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Bita Moghaddam @bita137.bsky.social · 31/08/2026
bsky.app/profile/bita...
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Bita Moghaddam @bita137.bsky.social · 31/08/2026
not my field but I'll some digging. I just recall the first paper long ago pubmed.ncbi.nlm.nih.gov/26158621/ and more recent drug discovery related papers pubs.acs.org/jmcmar/artic...
pubmed.ncbi.nlm.nih.gov
Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors - PubMed
Activation of cannabinoid CB1 receptors (CB1R) by delta9-tetrahydrocannabinol (THC) produces a variety of negative effects with major consequences in cannabis users that constitute important drawbacks for the use of cannabinoids as therapeutic agents. For this reason, there is a tremendous medical i …
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