Bita Moghaddam @bita137.bsky.social · 10hI learned my lesson a few years ago and never get them together after that 🥵🤒- giving a week between each shot makes a big difference, at least for me 020
Bita Moghaddam @bita137.bsky.social · 11hCongrats and about time!! Thank you for always being a kind and approachable colleague 040
Reposted by Bita MoghaddamMark Histed @markhisted.org · 19hNobel Prize awarded for optogenetics. Congrats to Karl Deisseroth, Hegemann, and Nagel. The prize is well-deserved, for work that has been transformative. a few quick thoughts 1/4 🧪#neuroscience 29825
Bita Moghaddam @bita137.bsky.social · 15hNice review AND we have actual data to support (or refute!) some of the theories here on how psychedelics may influence reward learning and behavioral flexibility www.biorxiv.org/content/10.6...biorxiv.orgPsilocybin asymmetrically modulates outcome-based choice and cortical processing under uncertaintyEmerging clinical research with psilocybin highlights the value of the psychedelic experience on successful treatment of a multitude of psychiatric disorders. While the psychedelic trip or clinical su... 061
Bita Moghaddam @bita137.bsky.social · 15hThis is a really nice review! And we have actual data in support of some of your prediction looking at the effect of psilocybin on the exact task shown on Figure 3 www.biorxiv.org/content/10.6...biorxiv.orgPsilocybin asymmetrically modulates outcome-based choice and cortical processing under uncertaintyEmerging clinical research with psilocybin highlights the value of the psychedelic experience on successful treatment of a multitude of psychiatric disorders. While the psychedelic trip or clinical su... 040
Bita Moghaddam @bita137.bsky.social · 30/09/2026yep. and the staging approach is not theoretically new but we finally have tools to begin to come of with treatment options that are stage-specific 000
Bita Moghaddam @bita137.bsky.social · 30/09/2026And I was not just theorizing: the ideas are supported by several recent preclinical papers including this from the lab www.nature.com/articles/s41...nature.comGrin2a knockout in adolescent dopamine neurons disrupts prediction error signaling and produces a phenotype relevant to schizophrenia - Molecular PsychiatryMolecular Psychiatry - Grin2a knockout in adolescent dopamine neurons disrupts prediction error signaling and produces a phenotype relevant to schizophrenia 061
Bita Moghaddam @bita137.bsky.social · 30/09/2026Please check out my futuristic opinion piece in @jamapsychiatry.com "specific treatments for schizophrenia that are tailored to target symptoms at different developmental stages are no longer the stuff of science fiction, but instead are realistic future goals" jamanetwork.com/journals/jam...jamanetwork.comUpdating Treatment Goals for SchizophreniaThis article discusses research providing renewed reasons to revisit the utility of glutamatergic drugs for treating schizophrenia. 22912
Bita Moghaddam @bita137.bsky.social · 29/09/2026uncanny resemblance of phraseology uses with this paper www.nature.com/articles/s41...nature.comInteracting spiral wave patterns underlie complex brain dynamics and are related to cognitive processing - Nature Human BehaviourUsing concepts mostly familiar to fluid physicists, the authors manage to elegantly tackle the complex problem of describing large-scale brain activity patterns, providing a rich foundation for the fu... 011
Reposted by Bita MoghaddamYohan J John @dryohanjohn.bsky.social · 28/09/2026Reading a review on serotonin by Peter Dayan and Quentin J.M. Huys from 2009. It's an increasingly rare experience in this LLM-blighted era to read a paper with good prose. 1277
Bita Moghaddam @bita137.bsky.social · 25/09/2026Treat it like preparing a meal for guests - people remember the first and the last (hors d'oeuvres and dessert) course better than the meal itself. So have solid intro and conclusion slides and don't worry about too much data in the middle 020
Reposted by Bita MoghaddamMark Baxter 🏳️🌈🧂 @markgbaxter.bsky.social · 24/09/2026If you work with international personnel, you may want to comment on this proposed rule change that would put visa holders out of status immediately (instead of after a 60 day grace period) when their employment ends keepthe60days.comkeepthe60days.comKeep the 60 Days: H-1B, E-3, L-1, O-1 & TN grace periodDHS proposes ending the 60-day grace period after a layoff for H-1B, E-3, L-1, O-1 and TN visa holders. Comment on USCIS-2026-0364 before November 10, 2026. 02839
Bita Moghaddam @bita137.bsky.social · 24/09/2026static.klipy.comVintage Typewriter in UseALT: Vintage Typewriter in Use 1111
Bita Moghaddam @bita137.bsky.social · 23/09/2026I am thoroughly impressed. I thought the tools in my lab are well organized but this is the next level 131
Bita Moghaddam @bita137.bsky.social · 23/09/2026destruction of creative thinking by 1) professional editors who take 3+ years to accept a paper asking for more & more data (yes reviewers ask for it but editors used to stop it) and 2) uni hiring committees who only interview young people with a massive dataset paper that their PI pushed for 160
Bita Moghaddam @bita137.bsky.social · 04/09/2026“If men could get pregnant, abortion would be a sacrament” Gloria Steinem 093
Bita Moghaddam @bita137.bsky.social · 04/09/2026I hope you at least get some raw milk during the coffee break 020
Bita Moghaddam @bita137.bsky.social · 04/09/2026It should not have mattered even if you were married to a billionaire. What your partner or parents make should not even enter the discussion/negotiation 110
Bita Moghaddam @bita137.bsky.social · 04/09/2026static.klipy.comIs That Legal Stan MarshALT: Is That Legal Stan Marsh 100
Bita Moghaddam @bita137.bsky.social · 04/09/2026and not in my current institution - this happened in the early 90s and how it "used to be" 020
Bita Moghaddam @bita137.bsky.social · 04/09/2026For my first academic position, I politely voiced concern that my salary was too low. I was told that your husband works too so the combined salaries should be considerable 4609
Reposted by Bita MoghaddamNeedhi Bhalla 💅🏽 @needhibhalla.bsky.social · 04/09/2026I went to Columbia for undergrad in 1991. It had only begun admitting women 4 years earlier, in 1987 69933
Reposted by Bita MoghaddamMatthew Baggott @mattbagg.eurosky.social · 03/09/2026This is a genuinely exciting (mouse) result that may address a big unmet need and seemingly works with non psychedelic 2A agonists (tabernanthalog worked). www.science.org/doi/10.1126/...science.orgPsilocybin prevents chemotherapy-induced peripheral neuropathy through mitochondrial trafficking preservationChemotherapy-induced peripheral neuropathy (CIPN) is a disabling, often irreversible toxicity that affects millions of patients, limits life-saving cancer therapy, and lacks proven treatment. In this ... 292
Reposted by Bita MoghaddamMichael Hobbes @michaelhobbes.bsky.social · 03/09/2026I’m sorry but this is never going to stop being funny 14780101
Bita Moghaddam @bita137.bsky.social · 03/09/2026THC (CB1 receptor stimulation) does activate BDNF via mTORC1 signaling but BDNF, currently the darling of the neuroplastigen field, is a ubiquitous molecule and activated by just about any drug experience (antipsychotics, chronic nicotine, etc) 120
Reposted by Bita MoghaddamAnn Powers @annkpowers.bsky.social · 03/09/2026All the mothers are going 04613
Reposted by Bita MoghaddamSamantha Butler @samanthabutler.bsky.social · 02/09/2026Please spread the news - the Department of Neurobiology at UCLA is hiring. This is an open rank search for all and any amazing neuroscientists! Please apply here by Nov 15th, first review end of October : recruit.apo.ucla.edu/JPF11296recruit.apo.ucla.eduOpen-rank tenure-track faculty positionUniversity of California, Los Angeles is hiring. Apply now! 06965
Reposted by Bita MoghaddamErin Rich @erinlrich.bsky.social · 02/09/2026Hey, we’ve been studying mnemonic chunking in🐒! With @fkchiang89.bsky.social Here’s the rundown: 🧵 www.cell.com/current-biol...cell.comCompression as a neural mechanism of mnemonic chunking in prefrontal cortexChiang and Rich show that macaques spontaneously chunk spatial targets in a self-ordered working memory task. dlPFC neurons compress chunked targets into lower-dimensional representations that are shi... 16921
Bita Moghaddam @bita137.bsky.social · 01/09/2026to be clear, I am all for #celebrating if not #bragging about PI and trainee wins, here, on LinkedIn and even on xwitter. My issue is with lack of genuine or useful information exchange 040
Reposted by Bita MoghaddamJeremy Hogeveen @jeremyhogeveen.bsky.social · 01/09/2026We ( @vincentcostaphd.bsky.social and I ) wrote a "Hot Topics" piece for @npp-journal.bsky.social on the potential utility of frontopolar cortex TMS in precision psychiatry. Relevant now that this region has been accessed in some excellent recent NHP studies. www.nature.com/articles/s41...nature.comTranslating macaque frontopolar cortex discoveries into psychiatric treatments - NeuropsychopharmacologyNeuropsychopharmacology - Translating macaque frontopolar cortex discoveries into psychiatric treatments 11712
Bita Moghaddam @bita137.bsky.social · 01/09/2026despite #icky experimental design, I am #thrilled the data is now out after 5 #glorious years of #delightful back and forth with the #brilliant journal editors 070
Bita Moghaddam @bita137.bsky.social · 01/09/2026I honestly see very little actual "discussion" about data even related to mundane safe questions. 130
Bita Moghaddam @bita137.bsky.social · 01/09/2026I know many scientists love Linkedin and are very active on it but I find it boring if not uninformative - my feed is 90% folks posting their latest awards or papers and others liking it 👏and/or replying congrats. No meaningful comments, no humor, no sarcasm, no disagreement What am I missing? 16531
Bita Moghaddam @bita137.bsky.social · 01/09/2026early 80s were truly the greatest years for movies 110
Bita Moghaddam @bita137.bsky.social · 01/09/2026static.klipy.comBlade Runner Japan: Futuristic CityscapeALT: Blade Runner Japan: Futuristic Cityscape 250
Reposted by Bita MoghaddamAlex Kwan @alexkwan.bsky.social · 31/08/2026Two large-scale electrophysiologyical studies of psilocybin's effects in mice, from @alleninstitute.org @torbenott.bsky.social and others. Should be a treasure trove of data for those interested in perceptual effects of #psychedelics www.biorxiv.org/content/10.6... www.biorxiv.org/content/10.6... 0389
Bita Moghaddam @bita137.bsky.social · 31/08/2026not my field but I'll some digging. I just recall the first paper long ago pubmed.ncbi.nlm.nih.gov/26158621/ and more recent drug discovery related papers pubs.acs.org/jmcmar/artic...pubmed.ncbi.nlm.nih.govCognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors - PubMedActivation of cannabinoid CB1 receptors (CB1R) by delta9-tetrahydrocannabinol (THC) produces a variety of negative effects with major consequences in cannabis users that constitute important drawbacks for the use of cannabinoids as therapeutic agents. For this reason, there is a tremendous medical i … 041