iiinova — where your digital self keeps evolving

Reposted by Andrew Savinov

Rikki Garner @rikkigarner.bsky.social · 16/09/2026

Excited to announce that the Rikki Garner lab has opened its doors in beautiful Austin, TX! Our interdisciplinary lab @utaustin.bsky.social MBS investigates tissue fluidity as a universal physical regulator of multicellular patterning in health and disease. www.rikkigarnerlab.org 1/n

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Andrew Savinov @biosavinov.bsky.social · 16/09/2026

Thrilled to announce that the Savinov lab is now live at UT Austin @utaustin.bsky.social! Our lab employs massively parallel experimental and AI methods to discover and design protein fragments as universal regulators of protein interactions in health and disease. www.savinovlab.com (1/n)

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Andrew Savinov @biosavinov.bsky.social · 13/05/2026

Interested in genetically encodable inhibitors of your favorite biomolecular condensate? Excited to announce our latest work, w/ Jibin Sadasivan, Gene-Wei Li, & Lindsay Case, on protein fragments as generalizable regulators of phase separation. (1/n) www.biorxiv.org/content/10.6...

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Rikki Garner @rikkigarner.bsky.social · 05/12/2025

If you're at #cellbio2025, @atmolines.bsky.social Hernan Garcia and I invite you to attend our Minisymposium “Physical Cell Biology from Molecules to Organisms” for incredible talks on epigenetic mechanical memory, viscoelasticity, cortical flows, morphogenesis, tissue wetting, size scaling, et al!

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Kate Cavanaugh @katecavanaugh.bsky.social · 06/12/2025

🚨 Link up with me at #Cellbio2025 ! 🚨 Excited to present the majority of my postdoc work in the Physical Cell Biology from Molecules to Organisms Minisymposium. Thanks to the organizers for putting together such an exciting session 🤩

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Liam J. Russell @liamjrussell99.bsky.social · 06/12/2025

Super excited to share some of my work in such a great session at #cellbio2025!! If you’re at the meeting come on down, I’ll be talking about cell density and its influence on tissue fluidization during epithelial morphogenesis 🔬👨🏻‍🔬🪰

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Rikki Garner @rikkigarner.bsky.social · 05/12/2025

Looking forward to seeing everyone at #cellbio2025! Excited to share new work from my postdoc to measure, model, and control the interplay of tissue fluidity and multicellular patterning in a living organism. Come see me at my talk or poster (details below), or DM me if you want to meet up!

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Andrew Savinov @biosavinov.bsky.social · 27/10/2025

Thrilled to contribute to this exciting work on protein binder design together w/ @hannes-stark.bsky.social , Felix Faltings, Regina Barzilay, Tommi Jaakkola, and co. We applied BoltzGen to design novel antimicrobial peptides targeting DNA gyrase based on inhibitory protein fragments. (1/n)

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Rikki Garner @rikkigarner.bsky.social · 23/10/2025

Happy to share that this work is now published in @biophysj.bsky.social! doi.org/10.1016/j.bp...

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Rikki Garner @rikkigarner.bsky.social · 10/09/2025

So honored to be speaking today at the Stanford.Berkeley.UCSF Next Generation Faculty Symposium! Hope to see you there! (Zoom registration link below)

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Rikki Garner @rikkigarner.bsky.social · 02/09/2025

Friendly reminder that the deadline to submit an abstract for talk at #cellbio2025 is TOMORROW, Wednesday, September 3, 2025 at 9 PM ET! Please consider submitting to our minisymposia "Physical Cell Biology from Molecules to Organisms (more details in the repost)

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Andrew Savinov @biosavinov.bsky.social · 04/08/2025

Check out this exciting new minisymposium at ASCB!

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MIT Department of Chemistry @mitchemistry.bsky.social · 02/07/2025

Congratulations to Barbara Imperiali, the Class of 1922 Professor of Chemistry and Biology, who has been elected as a Fellow of the Royal Society, the United Kingdom’s national academy of sciences. chemistry.mit.edu/chemistry-ne...

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Chrystal Starbird @drstarbird.bsky.social · 26/06/2025

The @berlowlab.bsky.social kicking off the next session at #PS39 If you missed his talk, Jake Simmons and Jamie Do of the Berlow lab will both be presenting posters at the afternoon session!

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Debraj Ghose @debrajghose.bsky.social · 05/05/2025

We found that cells use emergent collective memory—arising from simple chemical reactions—to outperform physical limits of detecting chemical gradients. Curious how? 1/n 8 min talk: www.youtube.com/watch?v=A7XH... bioRxiv: www.biorxiv.org/content/10.1... #biophysics #cellbiology

youtube.com

Local collective memory from ratiometric signaling outperforms cellular gradient sensing limits

YouTube video by Debraj Shubham Ghose

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Andrew Savinov @biosavinov.bsky.social · 09/06/2025

Excited to be at the @bostonbacteria.bsky.social‬ Meeting this year! I'll be a panelist at the AI in biology breakout session on Tuesday 6/10 after lunch, in Hall A -- together with ‪@microyunha.bsky.social‬ and M.S. Suryateja Jammalamadaka. Come join us for what should be a great discussion!

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Whitehead Institute @whiteheadinstitute.bsky.social · 30/04/2025

Whitehead Institute Member Yukiko Yamashita, who studies how genetic information is passed from parents to offspring, has been elected to the National Academy of Sciences. Full story on our website: wi.mit.edu/news/yukiko-...

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Arjun Raj @arjunraj.bsky.social · 28/04/2025

So excited to see this live! Awesome work from @giannatbusch.bsky.social on the concept of population-based synergy—using cell-to-cell heterogeneity to uncover new therapeutic vulnerabilities!

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Nick Polizzi @nickpolizzi.bsky.social · 28/04/2025

Super excited to share a new preprint from our lab on design of small-molecule binding proteins using neural networks! The paper has a bit of everything. A new graph neural network, new design algorithms, and experimental validation. www.biorxiv.org/content/10.1... 🧵🧪

biorxiv.org

Zero-shot design of drug-binding proteins via neural selection-expansion

Computational design of molecular recognition remains challenging despite advances in deep learning. The design of proteins that bind to small molecules has been particularly difficult because it requ...

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Reposted by Andrew Savinov

Alex Bisson @archaeon-alex.bsky.social · 24/04/2025

I'm the biggest fan of Rikki. Elegant physics. Breathtaking biology. If you're looking for a seminar speaker...she's a fantastic communicator. Congrats for the new work, @rikkigarner.bsky.social!

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Andrew Savinov @biosavinov.bsky.social · 24/04/2025

Check out this extremely thought-provoking work on tissue fluidity, cell motility, and patterning from @rikkigarner.bsky.social! Certainly changes how I think about development...

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Andrew Savinov @biosavinov.bsky.social · 11/02/2025

Also happy to share the @MITBiology news brief highlighting our @NIH-funded basic research which paves the way to systematically develop novel inhibitors and drugs, such as peptide-based antibiotics: biology.mit.edu/a-sum-of-the....

biology.mit.edu

A sum of their parts

All biological function is dependent on how different proteins interact with each other. Protein-protein interactions facilitate everything from transcribing DNA and controlling cell division to highe...

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Andrew Savinov @biosavinov.bsky.social · 05/02/2025

Happy to announce that our paper on systematically discovering peptides to inhibit protein-protein interactions in living cells is out now @pnas.org: www.pnas.org/doi/10.1073/.... @MITBiology @hhmi.bsky.social See thread on the updated preprint for details: x.com/bioSavinov/s...

pnas.org

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Proceedings of the National Academy of Sciences @pnas.org · 19/12/2024

Researchers engineered Escherichia coli bacteria to express an enzyme derived from sea sponges, which polymerizes bioglass from silica, allowing the bacteria to self-assemble lenses that focus light into narrow, intense beams. In PNAS: www.pnas.org/doi/full/10....

Maximum intensity projections for silicate in-expressing cells scattering light captured by a custom-built microscope capable of illuminating the bacteria at incident angles ranging from −90˚ to 90˚.

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Reposted by Andrew Savinov

Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 06/10/2024

⚠️ Tag with Caution ⚠️ New preprint led by Kerstin Dörner in Maria Hondele’s lab with contributions from Fan Cao on our side on the effects of tagging with FPs and peptides on condensation and phase separation 🧪 TL/DR: It’s complicated See more: doi.org/10.1101/2024...

Figure from paper showing simulation results of the effects of tagging

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