iiinova — where your digital self keeps evolving

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Spokane Rising @spokanerising.com · 29/09/2026

Send Stephen Miller to The Hague.

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Harmit Singh Malik @harmitmalik.bsky.social · 24/09/2026

I see that @anthropic.com is now competing with PhD students in Biology/Bioengineering labs, whose biggest worry until now was being inevitably scooped by the Feng Zhang and Jennifer Doudna labs. Very different from Wild West days of RT discoveries in my PhD. www.anthropic.com/news/claude-...

anthropic.com

Claude discovers a novel enzyme system

In early results from our new life sciences research lab, Claude agents found an enzyme system whose function is still unknown.

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Harmit Singh Malik @harmitmalik.bsky.social · 06/08/2026

Come be our colleague. I have been in this Division for 27 years (4 as a postdoc and 23 as a PI). It is an amazing place to work, collaborate, and be inspired. If you are applying to be an Assistant or Associate Professor this Fall, don't miss this deadline.

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wbialek.bsky.social @wbialek.bsky.social · 09/09/2026

We have been fortunate to have our community enriched by a remarkable stream of Fellows, both theorists and experimentalists. This is our annual effort at renewal. Please apply if it looks like a good fit!!

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Fred Hutch Biostatistics Program @fredhutchbiostat.bsky.social · 09/07/2026

🎉 Welcoming @biophysben.bsky.social to our Biostat Program in January 2027! He works across ML, physics, and biology, using generative models to map genetic drivers of disease, infer gene networks from sister cell data, and predict cellular responses from gene co-fluctuations. 🎉benkuznets-speck.com

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Fred Hutch Biostatistics Program @fredhutchbiostat.bsky.social · 09/07/2026

👀 We are super excited for Ben to bring his energy and ideas to Fred Hutch. Welcome, @biophysben.bsky.social !!

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Ben Kuznets-Speck @biophysben.bsky.social · 09/07/2026

Thrilled to announce I'll starting my lab in Biostatistics at Fred Hutch Cancer Center, where we'll fearlessly cross the boundaries of statistical physics, AI, and single-cell biology to study drug resistance, metastasis, and immune exhaustion! Huge thanks to everyone who made this possible.

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Ryan Estrada @ryanestrada.com · 24/06/2026

A cartoonist named Daniel "Des" Rolando Sanchez Estrada was tried as a terrorist and sentenced to 30 years in prison for having anti-Trump comics in his car. Prosecutors connected him to a 2025 anti-ICE protest he didn't even attend because he was in the same book club as others who were.

A photo of Daniel "Des" Rolando Sanchez Estrada, who looks like a cuddly and rad dude, smiling while holding a sketchbook full of drawings of baby hippos.

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People’s City Council - Los Angeles @pplscitycouncil.bsky.social · 23/06/2026

30 years for moving a box of zines. Des Sanchez Estrada was not even at the noise demo that led to this. The state is attempting to make an example of these anti-fascist political prisoners. We can expect the crackdowns to continue & escalate. Take this seriously. Don't back down

PRAIRIELAND
DEFENDANT SENTENCED TO 30 YEARS IN PRISON FOR MOVING A BOX OF ANTIFASCIST ZINES
Anti-ICE activists received lengthy prison terms - including a 100-year sentence — in the first major trial of the NSPM-7 era.

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 06/06/2026

They can control the copy right but we're all Tarheels. The Tar Heels ARE for everyone, and the UNC administrators who deleted this can go to hell.

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David Roberts @volts.wtf · 16/05/2026

Jesus Christ this is the most chilling thing I've read in ages. The "new understanding of truth" described here is not new in any way, it is basically a return to pre-literate dark ages & the inevitable result is going to be fascism.

wired.com

Gen Z Is Pioneering a New Understanding of Truth

The first generation to truly grow up online, Generation Z and their cohort live in a social media ecosystem that blends facts and feelings. It’s significantly shifting how they understand what’s true...

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Simon Fisher @profsimonfisher.bsky.social · 03/05/2026

Been training for this moment my whole life.

A 3x3 CAPTCHA grid showing different stock images of DNA, several of which have unusual left-handed double-helices, rather than the right-handed structure most typically seen in nature. To prove that the user is not a robot, they simply need to click on "all DNA stock images with messed-up chirality".

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NSF-Simons NITMB @nitmb.bsky.social · 17/04/2026

Travel applications for our upcoming workshop, ‘Cell State Transitions and Fate (in)decisions,’ are due in one week! Don’t miss your opportunity to join a community formalizing a unified framework for understanding plasticity and cell state-fate relationships www.nitmb.org/cell-state-t...

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Jen Bendery @jbendery.bsky.social · 31/03/2026

Just in: Supreme Court rules against law banning conversion therapy for minors. 8-1 decision. Justice Ketanji Brown Jackson was the lone dissenter. www.huffpost.com/entry/suprem...

huffpost.com

Supreme Court Rules Against Law Banning Conversion Therapy For Minors

The justices ruled 8-1, with Justice Ketanji Brown Jackson as the lone dissenter.

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The Washington Post @washingtonpost.com · 26/02/2026

Breaking news: A federal judge found that the IRS violated federal law “approximately 42,695 times” when it shared confidential taxpayer addresses with immigration enforcement officials last summer.

wapo.st

Judge: IRS broke law ‘approximately 42,695 times’ in giving DHS data

A court on Thursday issued an opinion on a data-sharing agreement between the taxpayer agency and federal immigration authorities.

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Brad Lander @bradlander.bsky.social · 18/02/2026

Shame on NYU Langone for ending gender-affirming care & kicking trans New Yorkers to the curb. It's a violation of their promise to treat all people equally, kindly, and respectfully — and a violation of NYC's human rights law as well. Bending the knee is bad; denying people care is even worse.

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Alejandra Caraballo @esqueer.net · 31/01/2026

The nazis redistributed the stolen property of deported Jews to the German population. It was called Aryanization. This is no different. en.wikipedia.org/wiki/Aryaniz...

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Mariya Savinov @mathbiosavinov.bsky.social · 22/01/2026

So excited to be co-organizing this!! If you're in the Chicago area, I highly recommend you join us for this 2.5 day workshop -- we have stellar speakers talking about all sorts of theory and biology. Make sure to apply before the deadline if you are interested!

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Suri Vaikuntanathan @vaikuntsuri.bsky.social · 17/12/2025

Excited to share new work by Daiki and Hector in collaboration with Monika: arxiv.org/abs/2512.13859 We introduce a gating mechanism in classic associative memory models and find capacity is increased far above the Hopfield limit without the usual catastrophic breakdown.

arxiv.org

Neuromodulation-inspired gated associative memory networks:extended memory retrieval and emergent multistability

Classical autoassociative memory models have been central to understanding emergent computations in recurrent neural circuits across diverse biological contexts. However, they typically neglect neurom...

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Suri Vaikuntanathan @vaikuntsuri.bsky.social · 17/12/2025

Super happy to be associated with this work !!

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Yogesh Goyal @goyallab.bsky.social · 02/12/2025

NEW PREPRINT led by stellar postdoc @biophysben.bsky.social We turn diffusion models into inference machines. Score function→exact likelihoods, uncertainty estimate & interpretablity. Diffusion models generate. But classify? Untapped—until now @chanzuckerberg.bsky.social shorturl.at/s32uX

shorturl.at

Interpretable Thermodynamic Score-based Classification of Relaxation Excursions

Classification and regression are cornerstones of computational biology and science at large, from identifying cell types to stratifying patients by disease state. Current deep learning classifiers pr...

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Ben Kuznets-Speck @biophysben.bsky.social · 02/12/2025

Today we’re excited to share Keeping SCORE, a framework that turns any diffusion model into a thermodynamic inference machine. Using only a model’s score function, we compute exact class likelihoods and uncertainty—and even decompose which features drove the decision. www.biorxiv.org/content/10.1...

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KaminskiMed @kaminskimed.bsky.social · 18/11/2025

Not sure why @lpachter.bsky.social did not post this here. But it is brilliant. Single cell genomics finally makes it to the clinic.

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Armita Nourmohammad @thearmita.bsky.social · 27/10/2025

excited to announce that this January we are relocating to Yale to start a theory initiative at the Center for Systems and Engineering Immunology (CSEI): @yalecsei.bsky.social looking to hire 2 postdocs to join us in this endeavor. more details can be found here: sites.google.com/uw.edu/statp...

sites.google.com

SPE - join us

Postdoctoral position: In January 2026, we are relocating to Yale university to start a theory initiative at the Center for Systems and Engineering Immunology (CSEI). We are looking for talented postd...

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Adam Rose @adamrose.bsky.social · 15/10/2025

Babies who are threat to DHS = 0 DHS teargas grenades thrown at babies = More than 0 (Before anyone blames adults for bringing baby there, video shows woman pull baby from her obstructed car to escape area. No indication she was there for a protest.)

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Rachel Maddow @maddow.bsky.social · 29/09/2025

www.nytimes.com/2025/09/29/u...

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Oded Rechavi @odedrechavi.bsky.social · 29/09/2025

Trying to log into Eduroam

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Victor Ray @victorerikray.bsky.social · 29/09/2025

There is no world in which masked and armed agents of the state running down delivery drivers makes us safer. That our information environment and political leaders have convinced people otherwise is a massive failure.

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Andrew White 🐦‍⬛ @andrew.diffuse.one · 26/09/2025

I finished my estimate on required compute to make an atomic-resolution virtual cell: 10^38 FLOPs to simulate a human cell for 1 day. We should be able to do this simulation in 2074 using 200 TW of power. 1/3

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Ben Kuznets-Speck @biophysben.bsky.social · 23/09/2025

Excited to share my new work on using AI and measured transcriptional responses to gene perturbations (knockdowns for example) to predict which sets of genes cause/mitigate complex disease phenotypes like cancer metastasis, IBD, or asthma, out now in PNAS! www.pnas.org/doi/full/10....

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NPR @npr.org · 26/08/2025

A whistleblower complaint says that the personal data of over 300 million Americans was copied to a private cloud account to allow access by members of the Department of Government Efficiency team.

n.pr

Whistleblower says Trump officials copied millions of Social Security numbers

A whistleblower complaint says that the personal data of over 300 million Americans was copied to a private cloud account to allow access by members of the Department of Government Efficiency team.

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Ran Blekhman @blekhman.bsky.social · 09/08/2025

This is not just HHMI. All Chan Zuckerberg Initiative funding calls are CLOSED. The Gates Foundation has no Grand Challenges funding opportunities. I've never seen anything like this. Private foundations have just decided to stop supporting biomedical research.

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Madhu Pai, MD, PhD @madhupai.bsky.social · 10/08/2025

A reminder that the mRNA vaccine technology saved millions of lives during the Covid pandemic and received the 2023 Nobel Prize for Medicine

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Harmit Singh Malik @harmitmalik.bsky.social · 08/08/2025

I don’t have a problem with someone evaluating my science abilities if I have the ability to examine theirs. Let’s do televised qualifying exams for all the political appointees who will be evaluating science grants and proposals. Let’s start with directors of institutes and cabinet secretaries.

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Nikolai Slavov @slavov-n.bsky.social · 24/07/2025

How challenging is the prediction of transcriptional responses to CRISPR gene perturbations ? A simple model, just scaling RNA correlation vectors, results in accurate predictions for many perturbations. The model is intuitive & grounded in a simple approximation. 1/2

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Rakyan Lab @rakyanlab.bsky.social · 17/07/2025

Paper in Nature 150 years ago. Beats reading any single-cell experiment…

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Matthew Facciani @matthewfacciani.bsky.social · 10/07/2025

"Grant cancellations and budget reductions at the National Institutes of Health have put millions of dollars in research for promising new cancer treatments, tuberculosis therapies, and much more in jeopardy." www.scientificamerican.com/article/atta...

scientificamerican.com

Apathy Over Attacks on Higher Education Needs to Change

If Americans don’t fight back against efforts to dismantle higher education, the U.S. will lose lifesaving medical research, innovation that spurs our economy and the ability to freely study science a...

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Carl T. Bergstrom @carlbergstrom.com · 09/07/2025

Under Trump, NOAA ran the most recent competition for their highly prestigious postdoc program in climate and global change — but funded no one, wasting huge amounts of applicant and reviewer time. It gets a lot worse. Now current postdocs in the program are going unpaid.

nytimes.com

Recipients of a U.S. Climate Science Fellowship Are Put on Unpaid Leave

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Yogesh Goyal @goyallab.bsky.social · 07/07/2025

Excited to share our paper on deciphering the design & control principles of tissue scaling w/ Luisa Arispe! Amazing work by co-first authors Danielle Pi and Jonas Braun. We show *differentiated* endothelial cell proliferate in waves with ultrafast cell cycle time of ~5h www.cell.com/cell-systems...

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Yogesh Goyal @goyallab.bsky.social · 06/07/2025

Excited to share our latest by my postdoc Ben KS: we use statistical physics & Bayesian inference to model genome-wide perturbation outcomes. Remarkably, perturbation responses are encoded in gene "chatter" even before the perturbation–a fundamental insight with broad implications shorturl.at/2LHbw

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