iiinova — where your digital self keeps evolving

Jonathan Jacobs @bioinformer.bsky.social · 09/10/2026

Note to self - OPEN YOUR EYES WHEN TALKING… I had no idea I did this. 😆🙃

030

Jonathan Jacobs @bioinformer.bsky.social · 09/10/2026

Congrats! Important area for agencies to be investing in too.

010

Reposted by Jonathan Jacobs

Jonathan Jacobs @bioinformer.bsky.social · 24/09/2026

ATCC Genome Portal Q3 2026 Release out Monday! genomes.atcc.org previews... New genome assemblies: 207 bacterial, 24 fungal, 15 viral. Plus new RNAseq datasets for 51 human cell lines and organoids (255 total samples, typically N=5 per line) #genomics #bioinformatics #aixbio #referencedata #NGS

153

Jonathan Jacobs @bioinformer.bsky.social · 29/09/2026

Well - at least we still have a edge for a little while longer...

021

Jonathan Jacobs @bioinformer.bsky.social · 24/09/2026

153

Reposted by Jonathan Jacobs

Magdalena Skipper @magdalenaskipper.bsky.social · 20/08/2026

Exclusive: NSF set to issue lowest number of new grants in four decades www.nature.com/articles/d41... 🧪 #AcademicSky @nature.com

34850

Reposted by Jonathan Jacobs

Jeff Dillon Fine Art @jeffdillonfineart.bsky.social · 07/07/2026

My name is Jeff Dillon and I'm a Canadian landscape painter. This is my art and I'd love to hear what you think. Jeff #art

7878281844

Jonathan Jacobs @bioinformer.bsky.social · 12/06/2026

I can not believe this is a legitimate journal… And if you haven’t looked into the fast paced and growing field of necrobots… please do. And please stick to the PEER REVIEWED papers only.

000

Jonathan Jacobs @bioinformer.bsky.social · 12/06/2026

Seems I’ve caught the writing bug. This is sort of follow up to my first SubStack post last week. Please take a look, repost and restack as well. Thank you!🙏 open.substack.com/pub/bioinfor...

open.substack.com

Reproducible Does Not Mean Correct

Reproducible Wrongness: When Genomics Gets the Same Answer for the Wrong Reason

020

Jonathan Jacobs @bioinformer.bsky.social · 07/06/2026

If you’re attending #ASMicrobe today and the #metadata / #microbiome dark matter session - you may be interested in my recent Substack article and preprint on this broad issue across all of #genomics open.substack.com/pub/bioinfor... interested? Send me a DM and let’s chat!

open.substack.com

Metadata as Infrastructure

Genomics data provenance and quality are something we can't ignore anymore

0103

Reposted by Jonathan Jacobs

Jonathan Jacobs @bioinformer.bsky.social · 06/06/2026

Metadata as Infrastructure. I finally created a Substack! My first post is on a topic that I probably spend entirely too much time worrying about. 😊 please reshare with your #genomics and #bioinformatics peeps! 🙏 🧬🦠🔬📊🧫🚀 substack.com/home/post/p-... #ASMicrobe #digitalbiology #biotech #biopharma

substack.com

Metadata as Infrastructure

Genomics data provenance and quality are something we can't ignore anymore

064

Jonathan Jacobs @bioinformer.bsky.social · 06/06/2026

Join ATCC’s Industry & Science Showcase today at the #ASMMicrobe conference and enjoy lunch on us while you learn. Discover how ATCC is supporting scientists in the fight against antimicrobial resistance with trusted strains and robust genomic resources. ow.ly/iv0950Z80wg

020

Jonathan Jacobs @bioinformer.bsky.social · 06/06/2026

substack.com

Metadata as Infrastructure

Genomics data provenance and quality are something we can't ignore anymore

064

Jonathan Jacobs @bioinformer.bsky.social · 06/06/2026

Hey #genomics and #bioinformatics community: I need an "endorsement" in order to submit a preprint to @arxiv.bsky.social 😭 I'm registered, but can't submit our preprint to q-bio\GN (Genomics) section until we get an endorsement from an existing arXiv author w/endorse privileges. that you? plz DM me🙏

022

Reposted by Jonathan Jacobs

Kaz Windness she/her @kazwindness.bsky.social · 05/06/2026

Make art with your hands. It’s what humans do. #noAI #artistssupportingartists #humanart

A graphic by author illustrator Kaz Windness that says make art with your human hands. And shows colorful hand outlines pressed up against the wall with colorful splatters behind them, reminiscent of hands in caves.

583561774

Jonathan Jacobs @bioinformer.bsky.social · 05/06/2026

And I could agree more. Slightly reworded for space from www.science.org/content/arti...

science.org

Science | AAAS

000

Jonathan Jacobs @bioinformer.bsky.social · 05/06/2026

“Every hour you spend confused is an hour spend building the infrastructure inside your own head that will eventually let you do original work,”… [by using AI tools]… “you haven’t saved time. You’ve forfeited the experience that the time was supposed to give you.” @minaskar.bsky.social

science.org

Amid a flood of AI advances, astrophysicists are questioning the soul of their field

Researchers see enormous power in new tools—but also the potential end of astrophysics as a human endeavor

140

Jonathan Jacobs @bioinformer.bsky.social · 05/06/2026

This is a thought provoking metaphysical piece that pulls at the strings of why we care so much (or don’t) as to whether AI can be better at everything than we can be. Absolutely love this. Thanks @aaas.org @science.org 🥰

031

Reposted by Jonathan Jacobs

Jonathan Jacobs @bioinformer.bsky.social · 21/06/2025

#ASMicrobe Gold. These are all great people.

3172

Reposted by Jonathan Jacobs

Scott V. Nguyen @scottnguyen.bsky.social · 05/06/2026

What if waste could become a resource? Join Dr. Ryan Bing as he explores how engineered microbes can transform waste feedstocks into valuable compounds. Looking forward to moderating this session! #ASMMicrobe @bioinformer.bsky.social

141

Reposted by Jonathan Jacobs

Stephen Turner @stephenturner.us · 05/06/2026

Biodefense in the Intelligence Age: openai.com/index/biodef... PDF: cdn.openai.com/pdf/biodefen...

openai.com

Biodefense in the Intelligence Age

An action plan for AI-powered biological resilience

021

Reposted by Jonathan Jacobs

Stephen Turner @stephenturner.us · 05/06/2026

Developing a standard definition for sequences of concern: www.frontiersin.org/journals/bio...

031

Jonathan Jacobs @bioinformer.bsky.social · 05/06/2026

#ASMicrobe rumors: attendees climbed out the window of a rooftop bar to retrieve someone’s backpack that had fallen out the window onto a lower rooftop. @tallcuppajoe.bsky.social ?

static.klipy.com

Nick Fury: I Will Neither Confirm Nor Deny

ALT: Nick Fury: I Will Neither Confirm Nor Deny

021

Reposted by Jonathan Jacobs

Dr Jamie Gallagher @jamiebgall.co.uk · 02/06/2026

It’s Pride 🏳️‍🌈 Spare one repost for a small creator? 🥺 My science and sci fi pins raise money for homeless LGBTQ+ people. Just sent another £800 to @aktcharity.bsky.social bringing total to £47,521 New for Pride 2026: 🌈Scientist🌈 🏳️‍🌈🐥🦜🦅🏳️‍🌈 🌈pronouns🌈 www.jamiebgall.co.uk/shop

Two bird pins. A series if birds sitting on a branch. Each bird is the colour of a stripe on the rainbow flag.

Pronoun pins with rainbow motif:
She her
He him
She they
He they
They them

An array of pride themed science and sci fi pins.

231097771

Reposted by Jonathan Jacobs

Stephen Turner @stephenturner.us · 02/06/2026

Once upon a time I was falling in love, but now I'm only falling apart 🎵 The total eclipse of bioinformatics: From disruption to convention, and a gentle warning journals.plos.org/ploscompbiol...

061

Jonathan Jacobs @bioinformer.bsky.social · 29/05/2026

I finally forked up the money to buy an original hardback version of S. Ohno’s infamous 1970 “Evolution by Gene Duplication” it’s wonderful. And I was super surprised and happy to find it had a page torn out of its book review in Science from 1972. 🤩

020

Reposted by Jonathan Jacobs

Binning Singletons @binningsingletons.com · 28/05/2026

It’s exciting to go to @asm.org #ASMicrobe but it can be intimidating if it’s your first time or you are alone (and even if you’re not!). We help you have a great meeting through our grassroots peer mentoring program. Join today! 🔬 🧪 🦠 #MicroSky #AMR binningsingletons.com/singleton/bi...

Distracted girlfriend meme. She’s wearing a name tag that says “Hello my name is Solo and 1st time attendees.” She’s checking out Binning Singletons while her guy, wearing a tag that says “Attending ASMicrobe without binsing”, is upset

079

Reposted by Jonathan Jacobs

James McInerney @jomcinerney.bsky.social · 11/05/2026

Paper: doi.org/10.64898/202... Code: github.com/mol-evol/pan... Pushback and alternative readings very welcome.

doi.org

5136

Jonathan Jacobs @bioinformer.bsky.social · 04/05/2026

It’s certainly more reasonable. Gemini is too.

010

Reposted by Jonathan Jacobs

Ida Bae Wells @nhannahjones.bsky.social · 29/04/2026

None of us take pleasure in being right: But we are in the Second Nadir. www.nytimes.com/2025/06/27/m...

nytimes.com

How Trump Upended 60 Years of Civil Rights in Two Months

161332309

Reposted by Jonathan Jacobs

Jasmine 🌌🔭 @astrojaz.bsky.social · 27/04/2026

i feel like society moved on from these too quickly

$A solar eclipse, captured from a camera mounted on one of the Orion spacecraft\u2019s solar array wings during the Artemis II crew\u2019s flyby of the Moon\u2019s far side. The Moon is dark, save for a bright halo of white light surrounding it. The Orion spacecraft is in the leftmost half of the image, mostly shadowed.$ The Moon and crescent Earth from Artemis II

The Moon and crescent Earth from Artemis II

$A crescent Earth setting behind the Moon\u2019s horizon. Credit: NASA$

A full disk image of Earth, as seen from the Orion capsule. The planet is a pale blue, swirling with white clouds and glowing slightly lighter blue in place from reflected light. From about 8 to 9 o'clock, a large brown landmass is Africa, with the Iberian peninsula twinkling with lights just where the planet curves. At the 1 o'clock spot, aurora glow in a thin green glow, just barely separated from the planet's surface. Earth is set against the black of space. Credit: NASA/Reid Wiseman

262151756

Reposted by Jonathan Jacobs

Kenneth Loi @kenjmloi.bsky.social · 27/04/2026

This work was co-led by myself and Peter Yoon. Structure was led by Peter, @terryzzy.bsky.social , and Trevor Docter. Many thanks to our intrepid collaborators and special thanks to Jennifer for supporting us through this project. www.biorxiv.org/content/10.6... www.biorxiv.org/content/10.6...

biorxiv.org

1439

Jonathan Jacobs @bioinformer.bsky.social · 28/04/2026

? Why does this need to be debunked ? It was about life imitating art.

010

Jonathan Jacobs @bioinformer.bsky.social · 27/04/2026

A “country of geniuses in a datacenter.” - @darioamodei.bsky.social (rereading this essay and it hits different even a few months later.. www.darioamodei.com/essay/the-ad... )

darioamodei.com

Dario Amodei — The Adolescence of Technology

Confronting and Overcoming the Risks of Powerful AI

000

Jonathan Jacobs @bioinformer.bsky.social · 27/04/2026

There are assemblies in GenBank and RefSeq where the methods are listed as “a bioinformatics pipeline” or something like that… I should bookmark these when I come across them…

000

Jonathan Jacobs @bioinformer.bsky.social · 27/04/2026

internal discussion about the shoddy job most publications do in describing their bioinformatics methods... and one of my team members replied with this... LMAO.. (used with permission)... so true. 💀

130

Jonathan Jacobs @bioinformer.bsky.social · 26/04/2026

Metadata as infrastructure Curation as design requirements not afterthoughts Reference materials as validation and benchmarking requirements This has to be the way moving forward

073

Reposted by Jonathan Jacobs

Pat Schloss @patschloss.bsky.social · 26/04/2026

I never got to meet Woese, but Ford and Pace have been fantastic to me. Regardless of whether people agree with them, they are/were deep thinkers. No shade to anyone of my generation or the next, but I'm not sure who is similarly gifted.

141

Jonathan Jacobs @bioinformer.bsky.social · 26/04/2026

And an RNA Biologist at heart - Carl Woese has been one of my hero’s since I was in grad school. 🙏

031

Jonathan Jacobs @bioinformer.bsky.social · 24/04/2026

I friggen love these old historical papers 🤗 !!!

120

Jonathan Jacobs @bioinformer.bsky.social · 22/04/2026

a couple more internal reviews - but i'm hoping to ship it soon. 🤞

010