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Benjamin Broomfield

@benjbroom.bsky.social
103 followers 80 following 3 posts

Immunologist & PhD Candidate @WEHI-research in Melbourne, Australia

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Reposted by Benjamin Broomfield
Journal of Experimental Medicine @jem.org · 09/01/2026
Transient inhibition of type I interferon enhances CD8⁺ T cell stemness and #vaccine protection. From Benjamin Broomfield @benjbroom.bsky.social, Joanna Groom @groomlab.bsky.social and colleagues 👉 rupress.org/jem/article/... 📘 In 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
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Reposted by Benjamin Broomfield
Joanna Groom @groomlab.bsky.social · 21/12/2025
Hey "Friends" The 2025 edition of our #AwkwardLabPhoto celebrates an incredible year of growth, publications, promotions, PhD submissions and grads I feel immensely proud and grateful to be part of this team
@brigetteduckworth.bsky.social @benjbroom.bsky.social @raymondqin.bsky.social @taylahjbennett.bsky.social @chinweetan.bsky.social
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Reposted by Benjamin Broomfield
Journal of Experimental Medicine @jem.org · 17/12/2025
The 2025 𝘉𝘦𝘴𝘵 𝘰𝘧 𝘑𝘌𝘔 highlights research in basic #immunology, #immunotherapy & #TumorImmunology, #InbornErrorsOfImmunity, #neurodegeneration, & #inflammation. We remain grounded in our commitment to publishing studies that push the boundaries of our knowledge forward 👉 rupress.org/jem/collecti...
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Reposted by Benjamin Broomfield
Joanna Groom @groomlab.bsky.social · 18/12/2025
🎉🥂 our @jem.org paper “Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection” is in the 2025 Best of JEM collection This work was led by @benjbroom.bsky.social @wehi-research.bsky.social check out the original thread.. bsky.app/profile/groo...
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Joanna Groom @groomlab.bsky.social · 07/12/2025
Another fantastic @ASI annual meeting, with @benjbroom.bsky.social (New Investigator finalist) and @brigetteduckworth.bsky.social (Symposia session) sharing the latest work from our lab. Loved catching up with old friends and hearing the current research from this brilliant network.
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Reposted by Benjamin Broomfield
Joanna Groom @groomlab.bsky.social · 30/09/2025
Thrilled to make the cover of @natimmunol.nature.com this month. A version of this warhol-inspired image has been in my head almost since we first conceived this Tfh diversity project (many, many years ago) @wehi-research.bsky.social
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Reposted by Benjamin Broomfield
Cyril Seillet, PhD @seilletlab.bsky.social · 02/06/2025
🎓 PhD positions available @MonashUni Join our lab to explore how neurons and immune cells shape gut immunity! 🧬 Single-cell RNAseq 🔬 3D imaging 🧠 Neuro-immune interactions 👥 Great mentoring & collaborations Apply now 👉 tinyurl.com/Seilletlab
tinyurl.com
Understanding the neuroimmune regulation of innate immunity | Supervisor Connect
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Reposted by Benjamin Broomfield
WEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · 19/05/2025
A landmark WEHI-led study has uncovered how our daily food choices are having an immediate effect on our gut health. Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint #chronicinflammation at the source. Now published in Immunity. www.wehi.edu.au/news/fast-fo...
Innate lymphoid cells 3 (ILC3s) are a subset of immune cells that are critical to gut immunity. When there is excess fat, such as after a rich meal, ILC3s store this fat in tiny lipid droplets to maintain their function. In this 3D illustration, we can see a lipid droplet (in orange) inside an ILC3.
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Reposted by Benjamin Broomfield
Lauren Howson @lauren-j-howson.bsky.social · 16/04/2025
🚨 New publication alert! 🚨 Thrilled to share our latest research out today in @jclinical-invest.bsky.social! This work is another great outcome of my amazing clinical research partnership with first author Samantha Chan and RMH. @wehi-research.bsky.social #immunology #research #JCI
jci.org
JCI - A dominant-negative IFNGR1 variant reveals broad immune cell sequestering of IFN-γ
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Reposted by Benjamin Broomfield
Joanna Groom @groomlab.bsky.social · 09/05/2025
Excited to have our latest research published in @jem.org this week and also highlighted by @natrevimmunol.nature.com @wehi-research.bsky.social @benjbroom.bsky.social
nature.com
Brief blockade of type I IFN increases CD8+ T cell memory - Nature Reviews Immunology
A study shows that transient blockade of type I interferon signalling during T cell priming enhances the generation of stem cell-like memory CD8+ T cells after viral infection and mRNA vaccination.
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Reposted by Benjamin Broomfield
WEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · 08/05/2025
Future vaccines a step closer. Research from @groomlab.bsky.social, @benjbroom.bsky.social and team use novel approach and mRNA tech to boost stem cell-like memory CD8+ T cells after vaccination. Published in @jem.org www.wehi.edu.au/news/vaccine...
A visualisation of immune cells, with headline "Long-lasting vaccines of the future a step closer"
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Reposted by Benjamin Broomfield
Journal of Experimental Medicine @jem.org · 05/05/2025
Our May issue is here! rupress.org/jem/issue/22... Cleary et al. (doi.org/10.1084/jem....) developed a new intravital technique for imaging pulmonary lymphatics. The cover depicts a 3D projection of a whole lung lobe with lymphatics (purple) and smooth muscle (white) labeled.
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Reposted by Benjamin Broomfield
Journal of Experimental Medicine @jem.org · 30/04/2025
@benjbroom.bsky.social et al. @groomlab.bsky.social show that transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection. rupress.org/jem/article/... 📘 In JEM #Immunology Collection: rupress.org/jem/collecti... #AAI2025
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Reposted by Benjamin Broomfield
Journal of Experimental Medicine @jem.org · 29/04/2025
This year's JEM #Immunology collection highlights recent findings in the field of B cells, CD8+ T cell stemness, priming and differentiation, CD4+ T cell heterogeneity, autoimmunity, lymphatic immunophysiology and innate immune signaling. 👉 rupress.org/jem/collecti... #AAI2025
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Le Xiong @lexiong.bsky.social · 15/04/2025
Thrilled to share our work now published on @cp-immunity.bsky.social . Big thanks to our collaborators. Here we show that short-term High-Fat diet impairs ILC3 functions in producing IL-22 through microbiota-dependent and-independent mechanisms.
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Reposted by Benjamin Broomfield
WEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · 10/04/2025
You’re invited! Celebrate the Day of Immunology at WEHI on 29 April. 🔹Hear from top scientists 🔹Discover the new Snow Centre for Immune Health 🔹Go behind the scenes with a lab tour 🔹Enjoy morning tea & meet the team Register now - www.immunology.org.au/events/-ASI-...
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Benjamin Broomfield @benjbroom.bsky.social · 17/03/2025
Happy one week of my @jem.org paper! Our work from the @groomlab.bsky.social at @wehi-research.bsky.social identifies using early IFN-I blockade alongside mRNA vaccination to direct CD8+ T cell positioning in the lymph node to drive Tscm cell differentiation and enhance vaccine protection
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Ivan Zanoni @lozanzi.bsky.social · 15/03/2025
#WeekendRead! #InterferonFriendOrFoe! @benjbroom.bsky.social @groomlab.bsky.social &co show @jem.org that transient type I IFN inhibition upon LCMV infection or a mRNA vaccine boosts stem-like memory CD8 T cells by altering their location within the draining lymph node, potentiating virus protection
rupress.org
Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection | Journal of Experimental Medicine | Rockefeller University Press
Broomfield et al. demonstrate that early type I interferon blockade alters CXCR3 chemokine regulation and cell location to promote an antigen-dependent CD8
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Joanna Groom @groomlab.bsky.social · 11/03/2025
Very excited our work out in @jem.org “Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection” @wehi-research.bsky.social led by talented (and determined) PhD student @benjbroom.bsky.social Thread below.
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Reposted by Benjamin Broomfield
Journal of Experimental Medicine @jem.org · 10/03/2025
@benjbroom.bsky.social et al. @groomlab.bsky.social show that early type I interferon blockade alters CXCR3 chemokine regulation & cell location to promote an antigen-dependent CD8+ T cell transition of precursor of exhausted T cells to stem cell–like memory CD8+ T cells rupress.org/jem/article/...
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Benjamin Broomfield @benjbroom.bsky.social · 19/12/2024
So lucky to be in a lab that does great science AND indulges in a weird photoshoot 🫶 Happy holidays!
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