iiinova — where your digital self keeps evolving

Babraham Institute @babrahaminst.bsky.social · 04/06/2026

Join our BioSCaPe PhD programme! You'll join an interdisciplinary, collaborative research environment and tackle fundamental biological questions with cutting-edge tools and expert supervision. Deadline 30th July. View the projects: buff.ly/Ex0o7rE

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Babraham Institute @babrahaminst.bsky.social · 26/01/2026

We are pleased to welcome Prof Sir Jim Smith as the Institute's Interim Director. Read more 👇

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Babraham Institute @babrahaminst.bsky.social · 15/01/2026

There is just one day left to register for our upcoming Frontiers in Stem Cell Innovation Conference! Join leading academics and industry professionals exploring cutting-edge stem cell technologies and disease modelling for drug discovery. View the full agenda and register now: buff.ly/ZiURhGV

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Babraham Institute @babrahaminst.bsky.social · 24/12/2025

Happy holidays from all of us at the Babraham Institute!✨Our card includes an image of a mouse intestine that has been stained for DNA (blue), e-cadherin (green) and muc2 (red). 📸 Petrina Tan, Christophorou lab

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Babraham Institute @babrahaminst.bsky.social · 23/12/2025

NEWS | Researchers ‘listen in’ to embryo-mother interactions during implantation using a culture system replicating the womb lining www.babraham.ac.uk/news/2025/12...

Microscopy image of a day 14 human embryo that has implanted in the new endometrial model.

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Babraham Institute @babrahaminst.bsky.social · 15/12/2025

Christmas special: buy one ticket, bring a colleague for free! Join leading academics, industry experts, and biotech innovators and explore next-generation stem cell technology, disease modelling, and translational breakthroughs at the Frontiers in Stem Cell Innovation Conference! buff.ly/oMmTmYd

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Babraham Institute @babrahaminst.bsky.social · 23/10/2025

Or watch one of our videos covering daily visual checks, cage cleaning, health checks, and enrichment provision: www.babraham.ac.uk/our-research...

Labelled black and white thumbnails of four video clips with titles: Cage cleaning, daily visual checks to ensure mouse welfare, Enrichment provision, Health checking our mice.

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Babraham Institute @babrahaminst.bsky.social · 23/10/2025

If you’re interested in seeing how we care for the mice, you can take a virtual tour of our animal facility: www.babraham.ac.uk/our-research...

Text reads: Take a 360 degree tour of our animal facility. Step 1: Visit. Step 2: Pick your route/area of interest. Step 3: Explore!

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Babraham Institute @babrahaminst.bsky.social · 23/10/2025

It’s #AnimalStats day in the UK today. You can see our animal stats at any time on our website, as well as finding out how and why we use mice in our research. www.babraham.ac.uk/our-research...

The graph title is: 2020-2024 Animal Use Statistics: Procedures & Severity
The graphic shows a horizontal bar chart showing the breakdown of severity numbers for each year from 2020 to 2024.

In 2024, a total of 30,389 procedures were carried out, with 23,257 being sub-threshold, 6,581 being mild, 516 being moderate and 35 being severe.
For previous years the data is as follows:
In 2023, a total of 33,364 procedures were carried out, with 25,585 being sub-threshold, 7,349 being mild, 375 being moderate and 55 being severe.
In 2022, a total of 39,157 procedures were carried out, with 4,069 being sub-threshold, 34,651 being mild, 389 being moderate and 48 being severe.
In 2021, a total of 40,750 procedures were carried out, with 4,008 being sub-threshold, 36,093 being mild, 514 being moderate and 135 being severe.
In 2020, a total of 48,599 procedures were carried out, with 7,613 being sub-threshold, 40,223 being mild, 664 being moderate and 99 being severe.

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Babraham Institute @babrahaminst.bsky.social · 16/10/2025

Interested in #StemCell research and technologies? Then hopefully this pairing of events is already marked in your calendar for February 2026. If not, take a longer look! www.eventbrite.co.uk/e/frontiers-...

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Frontiers in stem cell innovations, 5 & 6 February 2026
Wellcome Genome Campus and Babraham Research Campus, Cambridge, UK
Partnered with the Annual World Organoid and Organ-on-a-chip Research Day+ (WORD+)

Speakers
Lyle Armstrong - Newcastle University,
Bilada Bilican - AstraZeneca,
Adriana Buskin - Newcastle University,
Maria Christophorou - Babraham Institute,
Davide Danovi - Migration Biotherapeutics,
Fiona Ducotterd - Alzheimers Research UK & UCL,
Mark Kotter - Cambridge Stem Cell Institute & bit.bio,
Nick Ktistakis - Babraham Institute,
Marzena Kurzawa-Akanbi - Newcastle University,
Majlinda Lako - Newcastle University,
Rick Livesey - Talisman Therapeutics & UCL,
Matteo Martufi - GSK,
Fiona Menzies - Eli Lilly & Co,
Peter Rugg-Gunn - Babraham Institute,
Stefan Schoenfelder - Babraham Institute,

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Babraham Institute @babrahaminst.bsky.social · 30/09/2025

NEWS | A new multi-omics method enabling the profiling of multiple histone modifications and gene expression in single cells, and the researchers behind it, have been recognised with two awards. Congrats to the Rugg-Gunn lab and everyone involved! www.babraham.ac.uk/news/2025/09... #epigenetics

Text reads: News - Prizes for team behind game-changing multi-omics method to decode gene regulation. Image shows Dr Yang Wang (left) and Dr Peter Rugg-Gunn (right) shown over a data analysis plot from the scMTR-seq technique.

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Babraham Institute @babrahaminst.bsky.social · 08/09/2025

NEWS | Work just published by the Corcoran lab has described a mechanism estimated to be responsible for shaping the generation of up to half of all antibodies. www.babraham.ac.uk/news/2025/09/institute-immunologists-new-process-antibody-diversity @annecorcoran.bsky.social

Text reads: News - Institute immunologists uncover new process important for antibody diversity. Image shows a computer illustration of antibodies, showing the heavy chain (red) and the light chain (blue).

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Babraham Institute @babrahaminst.bsky.social · 01/09/2025

NEWS | We're delighted to welcome @diniscalado.bsky.social to the Institute as a senior group leader in our #immunology programme! The Calado lab works at the interface of immunity, #cancer, and #ageing. Learn more: www.babraham.ac.uk/news/2025/09...

Text reads: News: Institute welcomes Dr Dinis Calado as a senior group leader in the Immunology programme. Main image (left) shows Dinis Calado. Two images on the right are 3D confocal images of mouse bone marrow showing plasma cells (antibody producing cells; in red), endomucin⁺ vasculature (green), immunoglobulin (white), and cell nuclei stained with DAPI (blue). Credit: Abdouramane Camara, Immunity & Cancer Laboratory, The Francis Crick Institute.

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Babraham Institute @babrahaminst.bsky.social · 31/07/2025

Exciting news for @ukproteostasis.bsky.social and for #proteostasis researchers across the UK! Funding from BBSRC will support the development of the UK Proteostasis network, including: - connecting & building the community to accelerate research - supporting ECRs www.babraham.ac.uk/news/2025/07...

Abstract background representing network connections. Text reads: News - UK Proteostasis Network receives BBSRC Network Grant.

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Babraham Institute @babrahaminst.bsky.social · 30/07/2025

✋Hands up who loves #FlowCytometry? Then enjoy learning about how our annual Spectral Flow Cytometry Symposium is becoming an unmissable event (and note the dates for 2026). www.babraham.ac.uk/news/2025/07...

Image shows four parallel practical workshop sessions taking place in the Babraham Institute’s Flow Cytometry facility during the Spectral Flow Cytometry Symposium. Text reads: News - Institute’s Spectral Flow Cytometry Symposium provides a winning blend of insights and interaction.

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Babraham Institute @babrahaminst.bsky.social · 30/07/2025

BLOG | We had the pleasure of hosting Tomasz, a PhD student from the University of Leeds as a PIPS placement. In our latest blog article he describes how his exposure to the world of tech transfer has made him look at his research in a different way. www.babraham.ac.uk/blog/Tomasz-...

Photo of Tomasz on a stylised background. Text reads: Blog: A scientist in the business world - my PIPS placement with the Knowledge Exchange team. Article written by Tomasz Drobkiewicz, PhD student, University of Leeds.

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Babraham Institute @babrahaminst.bsky.social · 22/07/2025

We were honoured to host and hear from Tama Braithwaite-Westoby, Māori Engagement Advisor)/Tautotoro @malaghan.bsky.social for his seminar today: Innovating for Impact: Translating Immunology into Equitable Therapies for all in Aotearoa New Zealand.

Dr Theresa Pankhurst, Research Fellow at the Babraham Institute with Dr Tama Braithwaite-Westoby, Malaghan Institute of Medical Research.

Title slide from Tama's presentation: Innovating for Impact: Translating Immunology into Equitable Therapies for all in Aotearoa New Zealand.

The karakia (chant or blessing) gifted to the Malaghan Institute, shown in Māori on the left with the English translation on the right:
The sun rises, sends its rays into the sky
From beyond the skyline
The glow sent over the peaks on the sea
Casting a glow on the peaks inland at Pukehinua
Sending the spring's flow down Waikoukou
Stay on your path (the sun), rise up, reach your height
All darkness given light
Things unknown can be understood
The light can be found where? It is here.
It is

Closing slide from the presentation with text in Māori (top) and with English translation below: Together let's harness the power of the immune system, tackle health equity challenges and ultimately save lives.

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Babraham Institute @babrahaminst.bsky.social · 22/07/2025

Learn more about #AnimalResearch: step inside and explore what a mouse facility looks like and how it operates with our 360 virtual tour. More information about how and why we use mice in research on our website too. www.babraham.ac.uk/our-research...

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Babraham Institute @babrahaminst.bsky.social · 21/07/2025

Happy #MicroscopyMonday! This video, captured by Berta in the @trayon.bsky.social lab in collaboration with our Imaging facility, shows a mouse embryo dividing. This video allows researchers to visualise the events that happen before implantation at an early stage of development.

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Babraham Institute @babrahaminst.bsky.social · 11/07/2025

AWARD NEWS | Following Simon's award for Contribution to Research in the #PapinPrizes, our article covers just a slice of Simon's impact on the Institute's research, on #bioinformatics and on empowering researchers across the world by demystifying data analysis. www.babraham.ac.uk/news/2025/07...

Dr Simon Andrews, Head of Bioinformatics at the Babraham Institute, holding a certificate and an award for the 2025 Papin Prize for Contribution to Research. Image courtesy of The UK Institute for Technical Skills and Strategy. Photography by Alex Wilkinson Media.

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Babraham Institute @babrahaminst.bsky.social · 09/07/2025

NEWS | Thanks to BBSRC investment #MassSpectrometry capabilities at the Institute have been boosted by new high-throughput instrument, the Thermo Orbitrap Astral mass spectrometer. www.babraham.ac.uk/news/2025/07...

The Thermo Orbitrap Astral mass spectrometer, showing the sample introduction point for mass spectrometry analysis. Text reads: News - Mass spectrometry capabilities boosted by new high-throughput instrument.

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Babraham Institute @babrahaminst.bsky.social · 09/07/2025

This bowl of skittles means only one thing - our annual Spectral #FlowCytometry Symposium starts today! Missed out? Our facility offers training all year round: www.babraham.ac.uk/science-faci...

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Babraham Institute @babrahaminst.bsky.social · 09/07/2025

@drsimoncook.bsky.social is speaking at the #proteostasis session at #SEBconference this morning. In our feature, he describes how he's an "evangelist for discovery research" and the pipeline it feeds, and the Institute's growing strength in proteostasis. www.babraham.ac.uk/blog/2025/05...

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Babraham Institute @babrahaminst.bsky.social · 08/07/2025

At #SEBconference today, @delladavid-lab.bsky.social presented the group's research on understanding #ageing and protein aggregration. Della also played a key role in establishing the @ukproteostasis.bsky.social. She speaks about both themes in this feature. www.babraham.ac.uk/blog/2025/05...

Photo of Della David against an abstract background. Text reads: The rist and rise of proteostasis, with a quote by Della: "We are at a criticial moment to bring the community together and realise its potential."

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Babraham Institute @babrahaminst.bsky.social · 07/07/2025

This #MicroscopyMonday shows an image from research published last week. The images are of uveal melanoma cells showing the accumulation of lipid droplets in the absence of CDS2 (right), compared with cells with functional CDS2 (left). Lipid droplets are stained green with BODIPY™ 493/503.

Images show uveal melanoma cells showing the accumulation of lipid droplets in the absence of CDS2 (right), compared with cells with functional CDS2 (left). Lipid droplets are stained green with BODIPY™ 493/503. Image from Chan et al., Nature Genetics.

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Babraham Institute @babrahaminst.bsky.social · 04/07/2025

NEWS: Research just published by scientists from the @sangerinstitute.bsky.social and collaborators, including cell signalling experts at the Institute, has identified a new drug target to treat an aggressive eye cancer, and possibly other cancers too. ‬ www.babraham.ac.uk/news/2025/07...

Text reads: News - Signalling pathway research helps discover a new drug target for aggressive eye cancer. Images show uveal melanoma cells showing the accumulation of lipid droplets in the absence of CDS2 (right), compared with cells with functional CDS2 (left). Lipid droplets are stained green. Image from Chen et al., Nature Genetics.

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Babraham Institute @babrahaminst.bsky.social · 27/06/2025

Institute researchers, spanning research groups and facilities, contributed foundational knowledge about APDS, PI3-Kinase signalling and methodology central to the characterisation of APDS and the development of treatments. www.babraham.ac.uk/news/2025/06...

Text reads: News: First in-patient treatment received for life-threatening immunodeficiency syndrome. Images: Trio of images on a blue background. Left: the protein structure of PI3-Kinase delta in complex with a regulatory subunit and a bound inhibitor. Main image: Mary and her father Jimmy Catchpole with Dr Anita Chandra at Addenbrooke’s Hospital. Right: Leniolisib (Joenja). Middle and right image: both by Mel Yeneralski Media Studio. Copyright Cambridge University Hospitals.

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Babraham Institute @babrahaminst.bsky.social · 23/06/2025

We were honoured to receive the Research Culture in Research Management award at #ARMA2025 last week for the Institute’s Culture Consultation project to embed team science in our work. Congratulations to all teams recognised by the awards: #ResearchCulture #Advocacy #Innovation‬ #Management

ARMA certificate and awards for Research Culture in Research Management photographed outside the Babraham Institute lab building.
Certificate text reads: The Research Culture in Research Management award celebrates a project or initiative that has made a significant and positive impact to research culture, identifying challenges and opportunities and their resolution and enhancing the current culture across their organisation, sector or research ecosystem. Winner: The Institute Culture Consultation, Babraham Institute.
Perspex award: visible text reads: ARMA Award for Research Culture in Research Management. The Institute Culture Consultation, Babraham Institute.

The Institute’s Grants Officer, Jayashree Chakraborty and Project Manager, Stephen Barrett, with the award at ARMA's 2025 conference.

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Babraham Institute @babrahaminst.bsky.social · 03/06/2025

It's #BOARD25. Current research projects at the Institute are using mice to understand: 🧬 how what we eat affects the activity of our genes 💊 the increased susceptibility to disease with age ⌛how biological timing is encoded in the genome Learn more: www.babraham.ac.uk/our-research...

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Babraham Institute @babrahaminst.bsky.social · 02/06/2025

This #MicroscopyMonday comes to you from behind the scenes where Aurora, PhD student in the McGough lab, is imaging fly guts to look at proliferating cells! @ianmcgough.bsky.social‬

Aurora, with black hair in a ponytail, sits at a large computer screen with microscopy images of a fly gut in red in front of her.

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Babraham Institute @babrahaminst.bsky.social · 30/05/2025

Yesterday, our postdoc Francesca Rossi gave a seminar on the complex interplay of RNA-binding proteins, epigenetics & metabolism in immune cells at Sapienza’s School for Advanced Studies (SSAS) in Rome, where she was enrolled during her Bachelor’s, Master’s, and PhD at Sapienza University #ImmunoSky

Francesca in a blue suit next to the Italian, EU and University flag with her presentation on a display screen behind her

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Babraham Institute @babrahaminst.bsky.social · 30/05/2025

Happy 8 year anniversary for tomorrow @tech-commit.bsky.social! A great oppportunity to celebrate: - progress made through successive action plans, - our community of Technical Specialists, who are central to our research and operations, - coordinated national efforts and networks.

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Babraham Institute @babrahaminst.bsky.social · 19/05/2025

Did you see this research from the Turner lab? The team published the first description of the role of the ZFP36 family of RNA binding proteins in regulatory T cells. A step towards understanding age-related inflammation. www.babraham.ac.uk/news/2025/05... @martint-babraham.bsky.social #ImmunoSky

Representative images of sections (from L-R) of the lung, liver, and small intestine from control (upper panel) and knockout mice (lower panel). The arrows indicate accumulation of immune cells into these tissues. Text reads: News - Maintaining balance in the immune system.

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Babraham Institute @babrahaminst.bsky.social · 19/05/2025

We're excited to be welcoming Prof Paul Workman as the next speaker in our distinguished lecture series! Paul will cover the 15-year rollercoaster journey to discover the cancer drug NXP800 and its mechanisms 🧪 Register now to join us on 12th June: www.babraham.ac.uk/seminars/202...

Portrait of Paul Workman and event details copied from the website - 1-2pm, 12th June, Petersfield Lecture Theatre, Babraham

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Babraham Institute @babrahaminst.bsky.social · 16/05/2025

We're celebrating our superwoman of #FlowCytometry today - Head of our Flow Cytometry facility Rachael Walker who was Highly Commended in the Researcher of the Year category at the Cambridge Independent Science and Technology Awards last night!

Two polaroid-style images over a background of confetti. The image on the left shows Rachael accepting her award. The images on the right shows the award. Text reads: Congratualtions Rachael! Highly Commended: Researcher of the Year 2025. Cambridge Independent Science and Technology Awards

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Babraham Institute @babrahaminst.bsky.social · 14/05/2025

We're delighted to be retaining our Leader in Openness status. Take a look at our news item to learn about the progress we've made since our last Leader in Openness status renewal and thank you to everyone at the Institute who contributes to this important work. www.babraham.ac.uk/news/2025/05...

An animal technician holds a mouse in gloved hands. Text reads: News - Institute’s Leader in Openness status retained for transparency around animal research

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Babraham Institute @babrahaminst.bsky.social · 02/05/2025

That's the end of the Signalling Symposium and the end of an era. To quote Phill's closing words: "It's been a hell of a journey." Thank you to everyone for attending and making it such a fitting tribute.

Phill Hawkins and Len Stephens with Babraham Hall in the background

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Babraham Institute @babrahaminst.bsky.social · 02/05/2025

📢 Leaders of scientific facilities - read this perspective on change management in core facilities. Great piece on how to ensure the effective evolution of research facilities to meet external and internal change. Case studies: CEITEC, VIB & our Genomics facility

Figure show a stepwise model for supporting change within a core facility, featuring headlines and further explantory text. Step 1: Establish the sense of urgency. Step 2: Create guiding coalition. Step 3: Develop a vision and strategy. Step 4: Address cultural issues. Step 5: Manage the transition. Step 6: Sustain momentum.

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Babraham Institute @babrahaminst.bsky.social · 01/05/2025

What's the collective noun for @biochemsoc.bsky.social Morton Prize winners? We gathered together as many as we could get our hands on, including newest recipient Len. From left to right: Phill Hawkins, Peter Cullen, Robin Irvine, Peter Parker, Roger Williams, Len Stephens and Bob Mitchell.

A group of 8 people gathered together outside with a backdrop of the Babraham Research Campus. From left to right: Phill Hawkins, Peter Cullen, Robin Irvine, Peter Parker, Roger Williams, Len Stephens and Bob Mitchell.

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Babraham Institute @babrahaminst.bsky.social · 01/05/2025

Welcome everyone who is joining us for our two day Cellular signals for health & disease symposium! We're kicking off today with Len Stephens delivering the Biochemical Society Morton Lecture: buff.ly/NF0oSjk

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Babraham Institute @babrahaminst.bsky.social · 29/04/2025

Ahead of our celebratory symposium on 1-2 May to mark Len Stephen's and Phill Hawkins’s pioneering contributions to the PI3K signalling field, you might enjoy this feature with Len and Phill reflecting on their decades-long friendship, partnership – and fishing. www.babraham.ac.uk/blog/2021/11...

Len Stephens (shown left) and Phill Hawkins (shown right) with a background depicting colourful fish lures.

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Babraham Institute @babrahaminst.bsky.social · 24/04/2025

News from the Linterman lab - their comparison of B cell responses in the lung and lymph node showed the lung can support efficient B cell generated antibody development to the same extent as in the lymph node, albeit at a delay. www.babraham.ac.uk/news/2025/04...

Microscopy images of the germinal centres in the lymph node and the lung tissue

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Babraham Institute @babrahaminst.bsky.social · 22/04/2025

Babraham Distinguished Lecture 👨‍🏫Join us next week for Prof Jason Chin's lecture on reprogramming the genetic code. Registration required ➡️ www.eventbrite.co.uk/e/babraham-d... 🧪#MolBio

Tuesday 29th April, 1-2pm, Babraham Research Campus. Portrait of Prof Jason Chin, on a blue background

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Babraham Institute @babrahaminst.bsky.social · 08/04/2025

NEWS | We are delighted to congratulate our colleague Len Stephens on being awarded the 2026 Morton Lecture award from @biochemsoc.bsky.social for his outstanding contribution to lipid biochemistry #BiochemAwards www.babraham.ac.uk/news/2025/04...

Text reads: News - Dr Len Stephens awarded the Morton Lecture Prize. Main image shows Len Stephens with three images associated with his research area: Front image (left): Image of epithelia cells in the mouse prostate from a PTEN knockout mouse with red, orange and yellow cells showing early stages of tumour growth. Second image (top right): A section of a painting representing PI3K signalling as an electric circuit in the cell. Backmost image (bottom): Prostate tissue from a PTEN-knockout mouse stained to show hyperactive PI3K signalling.

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Babraham Institute @babrahaminst.bsky.social · 03/04/2025

📢Last chance to apply for the European B Cell Network Summer School, bringing together PhD students and postdocs with leading experts in B-cell immunology (inc. Kai-Michael Toellner). Event: 7–10 July in Lohr am Main, Germany Apply by: 7th April More info: www.b-cells.eu/ebcnet-2024-1 #ImmunoSky

2nd B Cell Summer School graphic, 7-10 July 2025, Lohr am Main, Germany. Graphic lists invited faculty and scientific organisers.

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Babraham Institute @babrahaminst.bsky.social · 02/04/2025

Thanks to our presenter @baptiste-piguet.bsky.social, PhD student in the @houseleylab.bsky.social, for delivering a session on neurodiversity today. Great primer offering the opportunity to learn and to consider preconceptions and the narrative around neurodiversity.

Baptiste and one of presentation slides: From Deficits to Strengths: How Neurodiversity changes the narrative.

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Babraham Institute @babrahaminst.bsky.social · 01/04/2025

AAALAC accreditation has been renewed for our animal facility, following rigorous external assessment. We're proud of the teamwork behind this achievement and the recognition that our facility, including our animal welfare practices, meets international standards. www.babraham.ac.uk/news/2025/03...

Text reads: News - Institute's animal facility retains AAALAC accreditation. Image shows a mouse in a plastic tunnel being held by gloved hands.

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Babraham Institute @babrahaminst.bsky.social · 07/03/2025

As Head of Research Operations, Danielle plays a key role in delivering scientific success. Co-founder of the UK Research Facility Coordinators Network, Chair of the @eu-life.bsky.social Core Facilities Working Group, and now a BIE Board member— her leadership is championing best practice!👏 #IWD2025

Image shows Danielle. Text reads: Danielle Hoyle, Head of Research Operations and Deputy Director of Operations. Babraham Institute Exterprise Non-Executive Directorship.

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Babraham Institute @babrahaminst.bsky.social · 07/03/2025

We highlight Hanane Hadj-Moussa @houseleylab.bsky.social, recipient of the Korenchevsky from the @bsrageing.bsky.social! Her work is shaping our understanding of biological #ageing, and we are excited about her attendance at the American Aging Association this May. 🌟 #IWD2025

Photo shows Hanane accepting her award from Prof. David Weinkove, President of the British Society for Research on Ageing. Text reads: Hanane Hadj-Moussa, Marie Skłodowska-Curie Fellow. British Society for Research on Ageing Korenchevsky Prize.

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Babraham Institute @babrahaminst.bsky.social · 07/03/2025

Laura Durrant is a champion for technical specialists! As Chair of our Technician Commitment Steering Group, she’s working to enhance visibility, recognition, and career growth for those who keep research moving forward. 🎯 #IWD2025 @tech-commit.bsky.social @uk-itss.bsky.social

Photos shows Laura holding a pipette. Text reads: Laura Durrant, Genomics specialist and Technician Commitment lead. Herschel Programme for Women in Technical Leadership.

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