iiinova — where your digital self keeps evolving

Anne Corcoran

@annecorcoran.bsky.social

154 followers 101 following 3 posts

Associate Group Leader @babrahaminst.bsky.social ‬; Affiliated Lecturer Pharmacology, University of Cambridge UK. Immunology, epigenetics, gene regulation & ageing. Fascinated by how B cells make antibodies. Passionate about equity & inclusion in science

Posts Replies Media

Anne Corcoran @annecorcoran.bsky.social · 10/09/2025

Delighted to share that our paper solving the age-old mystery of whether and how VH-replacement shapes the antibody repertoire is in @embojournal.org www.embopress.org/doi/full/10.... Fantastic work from Harry White, @peterch405.bsky.social @babraham-bioinf.bsky.social @babrahaminst.bsky.social

This shows an antibody heavy chain successfully pairing with a surrogate light chain and signalling B cell progression. In contrast a non-pairing heavy chain fails to signal, the B cell stalls, and the suboptimal V gene is replaced by an upstream V to make a pairing heavy chain and rescue the B cell.

0114

Reposted by Anne Corcoran

Department of Pharmacology | University of Cambridge @phar.cam.ac.uk · 12/02/2025

👩‍🔬To celebrate International Women and Girls in Science Day yesterday, our team interviewed Dr Catherine Wilson! We chatted to her about a range of topics surrounding being a Woman in Pharmacology - read her interview here: bit.ly/3COpzjZ #Interview #Pharmacology #Women #Cambridge

033

Anne Corcoran @annecorcoran.bsky.social · 11/02/2025

First post: It is a joy to CELEBRATE 10th Anniversary of International Day of Women and Girls in Science #IDWGS #WomenInScience #GirlsInSTEM Celebrating women and girls who have broken barriers and paved the way for future scientists. Let us continue to make our voices and talents heard and valued

picture of girl and woman high-fiving with floating images of DNA, planets, circuit board, test tube, pendulum

0133