iiinova — where your digital self keeps evolving

7/ This remains a hypothesis. But it turns an intriguing imaging finding into concrete, falsifiable questions about thalamic gain, bodily signal weighting and treatment response in ME/CFS. I thank the @sfb-trr-289.bsky.social for the support of this work!

6/ The key next step is to move beyond resting-state snapshots and track these processes within individuals after exertion, through the onset and peak of post-exertional malaise, and during recovery.

5/ This may provide one missing piece linking symptoms: sensory hypersensitivity, pain, orthostatic intolerance and cognitive “brain fog” could reflect a shared neurological gating disturbance across different domains.

4/ If thalamic filtering is altered, predictable ascending input may no longer be sufficiently attenuated. Signals that should remain in the background could instead dominate processing.

3/ The starting point is peripheral biology. Post-infectious immune, vascular, metabolic and autonomic disturbances can change the statistics of the body: the intensity, variability and reliability of the signals reaching the brain. The body the brain is inferring has changed.

2/ In this commentary, I argue that the thalamus may not simply relay bodily signals, but help determine how much they “count” by regulating their gain and precision.

Trends in Neurosciences @cp-trendsneuro.bsky.social · 24/07/2026

Reposted by Andreas Strube

'Brain rhythms of depression: A predictive processing perspective' by Andreas Strube @astrube.bsky.social & Diego Pizzagalli @diegopizzagalli.bsky.social www.cell.com/trends/neuro...

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Fabrice Hubschmid @hubschmidf.bsky.social · 30/06/2026

Glad to announce that our paper investigating the effect of action-outcome uncertainty on pain modulation is now out in @painthejournal.bsky.social 🧠💻! Super briefly: Learned certainty in what action lead to pain relief exagerates perception of pain relief. journals.lww.com/pain/fulltex...

journals.lww.com

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Andreas Strube @astrube.bsky.social · 25/06/2026

Vom Sonderforschungsbereich Treatment Expectation @sfb-trr-289.bsky.social wurde ich dazu interviewt, warum unser Gehirn wie eine Vorhersagemaschine ist - und wie Erwartungen unsere Wahrnehmung und unser Schmerzempfinden verändern können. Und was das für Jugendpsychiatrie bedeutet. Hier der Link:👇

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Andreas Strube @astrube.bsky.social · 23/06/2026

2/2 Among many exciting projects, we will use OPM-MEG task batteries in a large youth cohort at clinical high risk for psychosis, borderline personality disorder, and bipolar disorder - aiming to identify transdiagnostic neural mechanisms of vulnerability, resilience, and early intervention.

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Andreas Strube @astrube.bsky.social · 23/06/2026

1/2 Today was the launch event of the Einstein Center for Youth Mental Health in Berlin - funded by the @einsteinberlin.bsky.social. I am very excited to become part of this inspiring new environment as a postdoctoral researcher starting in October.

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Meike Ramon @meikeramon.bsky.social · 21/05/2026

Science Needs 3rd Spaces We envision scientific third spaces as “collaborative hubs where researchers, artists, engineers, and practitioners co-develop methods, share resources, and pursue projects driven by curiosity". authors.elsevier.com/sd/article/S...

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⚡️GREG_CORDER⚡️ @flybottleescape.bsky.social · 08/01/2026

🧠⚡️💊New @nature.com publication ! Mimicking opioid analgesia in cortical pain circuits We built a brain-behavior framework to decode spontaneous chronic pain in mice—and to biologically mimic morphine with a synthetic opioid gene therapy nature.com/articles/s41... @pennmedicine.bsky.social

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Andreas Strube @astrube.bsky.social · 06/06/2026

Many thanks to the @biodgps-dgpa.bsky.social and all colleagues for awarding me the DGPA Early Career Award 2026 at the fantastic #PuG2026! I am also grateful to the @sfb-trr-289.bsky.social for the support of my scientific work and the great research environment and network.

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Gamer Lab Wuerzburg @gamerlab.bsky.social · 20/04/2026

Are you a DGPA member (or thinking of becoming one 😁) conducting outstanding research in biopsychology, psychophysiology, or neuroscience? Apply now for the 2026 Early Career Award! @biodgps-dgpa.bsky.social

Ausschreibungstext für den DGPA Early Career Award 2026

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Goliathwatch @goliathwatch.bsky.social · 15/04/2026

🎬 Ein Film, der unter die Haut geht. 🎞 „Ich, Daniel Blake" – Ken Loachs mit der Goldenen Palme ausgezeichnet. Witz und Widerstand – britisch. Dienstag, 21. April · 19 Uhr 📍 Lichtmeß-Kino, Hamburg Mehr Infos: www.goliathtwatch.de #KenLoach #Lichtmeß #TaxTheRich #Pfeffersack #Film #Hamburg

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5/6 Bayesian modeling supports a prior intensity shift instead of a precision modulation. Those who expect to wait longer shift their top-down prior toward higher intensity.

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4/6 EEG reveals a clear dissociation: - Temporal expectations modulate α/β power during cue presentation (not during stimulation) - Prediction errors emerge in β/γ during stimulation - Actual stimulus latency is encoded in α/β frequencies

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3/6 Key finding: Expecting longer delays → higher intensity ratings. Actual delays? No effect. Prediction errors? No effect on ratings. This holds for painful heat AND non-painful cold, which suggest not a pain-specific phenomenon but a general somatosensory mechanism.

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2/6 The “dread effect” says that we prefer pain sooner rather than later. But is that driven by actually waiting longer, or by the expectation of waiting? Previous studies couldn’t disentangle the two.

Miriam Block @mibloq.bsky.social · 20/03/2026

1/6 Our paper is out today in Nature Communications! From the SFB/TRR 289 Treatment Expectation @sfb-trr-289.bsky.social we show that temporal expectations shape somatosensory perception - for both painful heat AND non-painful cold stimuli.

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🎬 Filme können Realitäten zeigen, die wir sonst leicht übersehen. Harburg Social Filmclub, Termin 2: „Souleymans Geschichte". Film u. Gespräch Miriam Block u. Anne Widder (NGG), Moderation Andreas Strube. 📅 Mo. 23.03. | 19:30 Uhr 📍 Schwarzenbergstr. 36, HH 📩 Anmeldung: filmclub@kinokulturhamburg.de

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Miriam Block @mibloq.bsky.social · 11/03/2026

🎬 Harburg Social Filmclub! Nächsten Montag: „Die jüngste Tochter" Danach Gespräch mit u.a. Andreas Strube (er/ihm), Miriam Block (sie/ihr), Han Kahrizi (keine Pronomen) & Juli Avemark (sie/keine). 📍 Schwarzenbergstr. 36 📅 Weitere Termine: 23.03. & 30.03. 📩 Anmeldung: filmclub@kinokulturhamburg.de

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Andreas Strube @astrube.bsky.social · 17/12/2025

In 10 Minuten – live! www.bundestag.de Fachgespräch zur Nationalen Dekade gegen postinfektiöse Erkrankungen im Ausschuss für Forschung & Technologie. Einschalten! Super spannend & sehr wichtig. #mecfs

bundestag.de

Deutscher Bundestag - Startseite

Internetseite des Deutschen Bundestages: Informationen über das Parlament und die Abgeordneten, Tagesordnungen, Livestreams und Service-Angebote.

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The Power of Expectations @sfb-trr-289.bsky.social · 18/11/2025

This might be a good moment to reshare our CRC starter pack, where you can follow all of our fantastic expectation researchers at once! 🤩

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The Power of Expectations @sfb-trr-289.bsky.social · 20/11/2025

Last order of business: ✨ PRIZES ✨ We congratulate four early career researchers who won best paper awards! 🤩 Huge congrats for doing amazing work, @astrube.bsky.social, Lieven Schenk, Justine Schmidt, and Stefanie Hölsken! 🥳

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Andreas Strube @astrube.bsky.social · 20/11/2025

Thank you so much for this honor - I’m very grateful. Sad I couldn’t be there in person, but congratulations to all awardees! ✨