Tamas Spisak @tspisak.bsky.social · 28/09/2026Beyond pain: a brain-based biomarker predicts individual pain relief 056
Tamas Spisak @tspisak.bsky.social · 25/08/2026Reinforcement Learning from Brain Feedback! Our new preprint by @ggallitto.bsky.social introduces an open-source framework and promising pilot results for using real-time fMRI to optimize (possibly AI-generated) stimuli to elicit a target neural response: doi.org/10.64898/202... 141
Reposted by Tamas SpisakThe Power of Expectations @sfb-trr-289.bsky.social · 03/08/2026⏰ New preprint ⏰ "Layer-specific cortical processing dissociates sensory and cognitive influences on pain" www.biorxiv.org/content/10.6... Collab w. @elh-institute.bsky.social, @tspisak.bsky.social, @ulrikebingel.bsky.social and some people not on here 😍 196
Reposted by Tamas SpisakThe Power of Expectations @sfb-trr-289.bsky.social · 22/07/2026💐✨ Huge congrats to Dr. Balint Kincses ✨💐 He has received the IFORES Career Kickstart grant for "Layers of pain: uncovering the mechanisms in the cortical integration of bottom-up and top-down processes in pain perception and its modulation using ultra-high field fMRI" @elh-institute.bsky.social 081
Reposted by Tamas SpisakThe Power of Expectations @sfb-trr-289.bsky.social · 20/07/2026More than words: Experience shapes #placebo pain relief through additional brain pathways 🧠 We're excited to share our latest publication in @natcomms.nature.com! 🤩 🔗 Read the paper: rdcu.be/fuxmn #neuroskyence #PsychSciSky #Neuroscience #PainResearch #BrainImaging #TeamScience #Reproducibility 11810
Tamas Spisak @tspisak.bsky.social · 19/05/2026Many of you asked how we create those pretty whole-brain plots with the cortical outline. We just made it available as a Python package: pni-lab.github.io/quickbrain/ 35923
Tamas Spisak @tspisak.bsky.social · 28/04/2026The brain’s “default mode” and “action mode” networks are two sides of the same attractor. Encoding a macro-scale Bayesian prior that biases processing toward internal or external drive. 020
Tamas Spisak @tspisak.bsky.social · 22/04/2026Looking forward to the colloquium in Bochum next Wednesday! www.ini.rub.de/events/ 030
Tamas Spisak @tspisak.bsky.social · 17/04/2026Our work with Karl Friston on Self-Orthogonalizing Attractor Neural Networks is now out in Neurocomputing! What does this theoretical model mean for our understanding of the brain? I’ve mapped out the key neuroscience implications below. Read the thread for a neuroscience walk-through ↓ 273
Tamas Spisak @tspisak.bsky.social · 16/04/2026Really exciting to see my pTFCE work re-implemented in Python and taken even further by an independent group. Great to know pTFCE is in good hands! github.com/Don-Yin/pytfce arxiv.org/abs/2603.11344github.comGitHub - Don-Yin/pytfce: Fast probabilistic Threshold-Free Cluster Enhancement in PythonFast probabilistic Threshold-Free Cluster Enhancement in Python - Don-Yin/pytfce 000
Tamas Spisak @tspisak.bsky.social · 19/03/2026Out in @elife.bsky.social: Functional connectivity-based attractor dynamics of the human brain in rest, task, and disease doi.org/10.7554/eLif... 052
Tamas Spisak @tspisak.bsky.social · 12/01/2026Brain attractors are approximately orthogonal to each other, suggesting that the brain may function as a self-orthogonalizing attractor network. Check out our revised manuscript about functional connectivity-based brain attractor dynamics in @elife.bsky.social. Link in comment! 1115
Tamas Spisak @tspisak.bsky.social · 07/11/2025Replicability of BWAS with functional and structural MRI has been hotly debated. But what about DWI? Our new paper - first authored by @rkotikalapudi.bsky.social - shows that multivariate DWI models of trait-like phenotypes can be replicable, even with moderate sample sizes. 🔗 Link in comment! 111
Reposted by Tamas SpisakOle Goltermann @olegolt.bsky.social · 22/07/2025Serious concerns about a new cortical biomarker for pain sensitivity jamanetwork.com/journals/jam... We (with @tspisak.bsky.social, @christianbuchel.bsky.social) published a commentary on Chowdhury, Bi et al. (2025, JAMA Neurology) raising serious concerns about their reported results. 👇 1/13jamanetwork.comConcern About Predictive Performance of a Pain Sensitivity BiomarkerTo the Editor Chowdhury et al1 evaluated a biomarker for pain sensitivity, combining peak alpha frequency and corticomotor excitability. The authors report outstanding performance (validation set area... 47336
Tamas Spisak @tspisak.bsky.social · 30/05/2025As many of you know, I’ve been fascinated by brain attractor dynamics lately. Thrilled to share a new preprint on their link to orthogonal neural representations, co-authored with Karl Friston: arxiv.org/abs/2505.22749 - with implications for both neuroscience & AI! First in a series - stay tuned!arxiv.orgSelf-orthogonalizing attractor neural networks emerging from the free energy principleAttractor dynamics are a hallmark of many complex systems, including the brain. Understanding how such self-organizing dynamics emerge from first principles is crucial for advancing our understanding ... 32910
Tamas Spisak @tspisak.bsky.social · 28/05/2025🚨 New paper out in GigaScience! To avoid common pitfalls in multivariate modeling: combine external validation with pre-registration — freeze your model before testing. For the pros: decide on the fly when to stop training! First-authored by the brilliant @ggallitto.bsky.social 163
