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Antonio Regalado

@antonioregalado.bsky.social
3K followers 557 following 154 posts

Journalist covering biotechnology for MIT Technology Review. Scoops about new methods in genetics and cell biology. The "playing God" beat. Gene editing, gene therapy, ancient DNA, synthetic embryos, cloning, etc.

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Antonio Regalado @antonioregalado.bsky.social · 10/12/2025
Have a smarter baby? You might, but it's not necessarily legal to advertise. Our look at the NYC subway ad campaign by IVF embryo profiling company Nucleus and how it collides with anti-discrimination statutes that apply to advertising on public property. www.technologyreview.com/2025/12/05/1...
technologyreview.com
The ads that sell the sizzle of genetic trait discrimination
A startup’s ads for controversial embryo tests hit the New York City subway.
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Antonio Regalado @antonioregalado.bsky.social · 04/12/2025
I am preparing MIT Technology Review's infamous list of "worst" technologies of the year. What are 2025's biggest failures, set backs, and misfires but which also hold useful lessons about technology? I think Cybertruck has to be on the list. Tell me your picks in the replies👇!!
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Antonio Regalado @antonioregalado.bsky.social · 10/11/2025
A month after Bari Weiss hired to lead CBS News division, heretic eugenics philosopher Jonathan Anomaly is on the morning show pitching bell curves and embryo scores. www.youtube.com/watch?v=qvVM...
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Adrian Woolfson @adrianwoolfson.bsky.social · 10/11/2025
I tremendously enjoyed Matthew Cobb’s definitive new biography of Crick. It was hard to put down and provides many new perspectives. My review of it will appear in Science later this week.
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Hank Greely @hankgreely.bsky.social · 04/11/2025
A 3rd (?) germline editing co announced @antonioregalado.bsky.social in @technologyreview.com, www.technologyreview.com/2025/10/31/1... I mainly share Fyodor's reaction, quoted in story—"In his email, Urnov said the launch of still another venture into the area made him want to “howl with pain.”
technologyreview.com
Here’s the latest company planning for gene-edited babies
Entrepreneurs say it’s time to safety-test designer baby technology.
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Jason Moore @moorejh.bsky.social · 21/10/2025
#password
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Antonio Regalado @antonioregalado.bsky.social · 21/10/2025
The astonishing science of synthetic embryology and our profile of it's most ambitious praticioner, Jacob Hanna www.technologyreview.com/2025/10/21/1...
technologyreview.com
The astonishing embryo models of Jacob Hanna
Scientists are creating the beginnings of bodies without sperm or eggs. How far should they be allowed to go?
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Antonio Regalado @antonioregalado.bsky.social · 06/10/2025
Read this item by TB researcher whose grant got cancelled as 'dangerous gain of function.' Ironic, because the administration (RFK), has promoted whole‑virus vaccines, whose development, especially if they are attenuated, probably relies on very similar techniques.
hhs.gov
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Antonio Regalado @antonioregalado.bsky.social · 17/09/2025
Here come the first "generative" genomes. Folks at the Arc Institute used an AI trained on DNA sequence to propose code for novel bacteriophage genomes. Of the 302 they synthesized, 16 actually worked--replicating and killing E. Coli. www.technologyreview.com/2025/09/17/1...
technologyreview.com
AI-designed viruses are here and already killing bacteria
Can AI create a life form? These “generative” genomes are a start
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Niall Firth @niallfirth.bsky.social · 17/09/2025
Can AI create a life form? These "generative" genomes are a start. New from @antonioregalado.bsky.social www.technologyreview.com/2025/09/17/1...
technologyreview.com
AI-designed viruses are here and already killing bacteria
Can AI create a life form? These "generative" genomes are a start
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Dr. D Boulware, MD MPH @drboulware.bsky.social · 24/06/2025
Can anyone find a Berman MF et al. Neurotoxicology 2008; 29(5), 914–922 ? This is a fake citation. www.sciencedirect.com/journal/neur...
sciencedirect.com
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Antonio Regalado @antonioregalado.bsky.social · 06/06/2025
World famous synthetic embryo scientist stopped while entering U.S. Agent: Any embryos in your luggage? Scientist: One sec. [Opens guideline booklet of the International Society for Stem Cell Research.] Scientist: Nope, just 3-D structures derived from pluripotent stem cells.
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Antonio Regalado @antonioregalado.bsky.social · 05/06/2025
Coinbase CEO, net worth ~$10B, wants to start definitive embryo editing company in the US. Making a gene-edit baby is prohibited in most of the world. But the winds can change. www.technologyreview.com/2025/06/05/1...
technologyreview.com
Crypto billionaire Brian Armstrong is ready to invest in CRISPR baby tech
The stigmatized idea could get a massive boost from “tech bros”—and some scientists are cheering them on.
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Antonio Regalado @antonioregalado.bsky.social · 29/05/2025
OMG. Government "Make America Healthy Again" report has references to non-existent papers, suggesting US medical policy is partly plagiarized AI slop. Calling on author, NIH director @drjbhattacharya.bsky.social‬ to issue correction + investigate AI plagiarism www.notus.org/health-scien...
notus.org
The MAHA Report Cites Studies That Don’t Exist
The Trump administration’s “Make America Healthy Again” report misinterprets some studies and cites others that don’t exist, according to the listed authors.
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Antonio Regalado @antonioregalado.bsky.social · 27/05/2025
Japanese company to remove anachronisms from corporate names. What other companies have anachronisms in their names or logos?
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Cathy Gao-Howard MD MS @catgaohow.bsky.social · 18/05/2025
Northwestern has not received any NIH funds since March. No written communication about why or what can be done. Thank you Ben Singer for raising awareness at #ATS2025
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Antonio Regalado @antonioregalado.bsky.social · 07/05/2025
Patient was posting from a Musk implant, with the help of Musk's AI, on a Musk media platform and in reply to a Musk fanboy, if not actually the “alt” of the richest person in the world. So it’s fair to ask: Where does patient end and Musk’s ecosystem begin? www.technologyreview.com/2025/05/07/1...
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Antonio Regalado @antonioregalado.bsky.social · 01/05/2025
This is pig. I mean big. FDA approves gene-edited pig resistant to common swine virus. more 👇https://www.pig-world.co.uk/news/pic-receives-us-approval-for-gene-edited-prrs-resistant-pigs.html
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Antonio Regalado @antonioregalado.bsky.social · 16/04/2025
Let biotechnology bring forth mammoths™ and birds™ and beasts™ of every kind. And it was so.
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Antonio Regalado @antonioregalado.bsky.social · 16/04/2025
Colossal Biosciences is trying to win patents on the "Woolly mammoth" and the "dire wolf." www.technologyreview.com/2025/04/16/1...
technologyreview.com
Jurassic Patent: How Colossal Biosciences is attempting to own the “woolly mammoth”
The company claiming it can restore lost species also wants to patent them.
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Hank Greely @hankgreely.bsky.social · 26/03/2025
Dream on. As Antonio knows, head transplants were done decades in dogs & monkeys but sad failures. And Sergio Canavero kept promising human ones "by the end of the year" (For a decade?) Anyway (the great) Lois McMaster Bujold (winner of FOUR best novel Hugos) got there decades ago.
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Hank Greely @hankgreely.bsky.social · 26/03/2025
This paper is the weirdest & most unsettling thing I've ever (co)written. & HUGE science questions—not just ectogenesis, but could a "brainless" animal survive? would it be a good model for a "real" animal? And ethics question, which are much bigger with humans. But I think it needs discussion.
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Antonio Regalado @antonioregalado.bsky.social · 25/03/2025
Imagine human bodies grown without complete brains, without consciousness. These are "bodyoids." And today in MIT Technology Review, researchers from Stanford University are ready to talk about them. www.technologyreview.com/2025/03/25/1...
technologyreview.com
Ethically sourced “spare” human bodies could revolutionize medicine
Human “bodyoids” could reduce animal testing, improve drug development, and alleviate organ shortages.
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Catherine Rampell @crampell.bsky.social · 19/03/2025
Email sent to FDA staff informs that agency leadership canceled the agency's LexisNexis subscription, even though staff need this tool to research legal and regulatory information as part of their jobs. I'm reproducing the text of the email here:
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Antonio Regalado @antonioregalado.bsky.social · 19/03/2025
For $19.99, couldn't resist this addition to my biotech t-shirt collection.
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Marc Dionne @marcsdionne.bsky.social · 04/03/2025
GIVE THEM TRUNKS YOU COWARDS www.theguardian.com/science/2025...
theguardian.com
Scientists aiming to bring back woolly mammoth create woolly mice
Genetically modified mice have traits geared towards cold tolerance, in step towards modifying elephants
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Antonio Regalado @antonioregalado.bsky.social · 18/02/2025
We looked into the booming field of ancient DNA research, how it's telling stories from pre-history and how some of the old information is being teleported into the present and added to plants in a bid to defeat climate change. www.technologyreview.com/2025/02/17/1...
technologyreview.com
Adventures in the genetic time machine
Ancient DNA is telling us more and more about humans and environments long past. Could it also help rescue the future?
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Antonio Regalado @antonioregalado.bsky.social · 14/02/2025
Renee Wegrzyn Founding director of ARPA-H (the DARPA of medical research) is out of a job, and apparently very suddenly.
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Christophe Veltsos @drinfosec.bsky.social · 10/02/2025
This 👇is a 🎯 all-in-one H5N1 tracking tool to bookmark & share: H5N1 US Tracker - Ginkgo Biosecurity www.ginkgobiosecurity.com/h5n1-us-trac... H/t @rhonda234567.bsky.social
Colored map of the US showing various cases of H5N1 across different species including human cases, dairy farms, poultry farms, wild birds, other wildlife.
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Antonio Regalado @antonioregalado.bsky.social · 17/01/2025
Google DeepMind won a Nobel Prize for protein prediction. Now OpenAI says it's getting into the game as well, with model trained on protein sequences that' being used in longevity research. www.technologyreview.com/2025/01/17/1...
technologyreview.com
OpenAI has created an AI model for longevity science
The company is making a foray into scientific discovery with an AI built to help manufacture stem cells.
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Antonio Regalado @antonioregalado.bsky.social · 16/01/2025
What to expect from Elon Musk's Neuralink in 2025. www.technologyreview.com/2025/01/16/1...
technologyreview.com
What to expect from Neuralink in 2025
More volunteers will get Elon Musk’s brain implant, but don’t expect a product soon.
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Antonio Regalado @antonioregalado.bsky.social · 06/01/2025
Doc, does this mean I shouldn't swallow the toothpaste?
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Antonio Regalado @antonioregalado.bsky.social · 04/01/2025
Technical drawing of an infant gestating inside an artificial womb. Emanuel M. Greenberg, ARTIFICIAL UTERUS, U.S. Patent No. 2,723,660 (November 15, 1955)
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Antonio Regalado @antonioregalado.bsky.social · 03/01/2025
Ancient DNA. Often said that the number of old human skeletons whose DNA is being sequence is increasing "exponentially." Here is the data, from the Allen Resource for ancient DNA. I mean, the trend is more...punctuated linearity? Someone help me feel ok calling this exponential.
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Antonio Regalado @antonioregalado.bsky.social · 03/01/2025
MIT Technology Review annual list of 10 Breakthrough Technologies of the year. They are: Vera C. Rubin Observatory Generative AI search Small language models Cattle burping remedies Robotaxis Cleaner jet fuel Fast-learning robots HIV prevention med Green steel Stem-cell therapies that work
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Antonio Regalado @antonioregalado.bsky.social · 03/01/2025
An accumulation of somatic mutations cause cancer. But do they also cause a misunderstood class of other conditions that aren't inborn, but arise in adulthood? An M.D. writing in Atlantic draws together some rare examples. www.theatlantic.com/health/archi...
theatlantic.com
Doctors Thought They Knew What a Genetic Disease Is. They Were Wrong.
Mutations that happen throughout a person’s life may contribute to disease more than we realized.
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Antonio Regalado @antonioregalado.bsky.social · 30/12/2024
New documentary follows career of MIT prof Phil Sharp and rise of biotech industry. Sharp shared 1993 Nobel for how RNA codes proteins and he co-founded founded Biogen, Alnylam, among others. Director is Bill Haney, a biotech exec. www.youtube.com/watch?v=ruJd...
youtube.com
Cracking the Code: Phil Sharp and the Biotech Revolution [Official Trailer]
YouTube video by Uncommon Productions
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Science Magazine @science.org · 20/12/2024
In the 20 years since the term “microplastics” was first coined, a growing body of research has consistently shown how pervasive and problematic the pollutants have become. A recent #ScienceReview provides an overview and the progress made in understanding #microplastics.
scim.ag
Twenty years of microplastic pollution research—what have we learned?
Twenty years after the first publication that used the term microplastic, we review current understanding, refine definitions, and consider future prospects. Microplastics arise from multiple sources, including tires, textiles, cosmetics, paint, and the...
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Antonio Regalado @antonioregalado.bsky.social · 20/12/2024
5.5% of prescriptions doctors write in the U.S. are for GLP-1 agonists like Wegovy/Ozempic. Up from 1% in 2021 -used for diabetes and weight loss -women 2X as likely -50% of scripts for weight loss unfilled (presumably, due to high price) www.technologyreview.com/2024/12/20/1...
technologyreview.com
Drugs like Ozempic now make up 5% of prescriptions in the US
The ever-increasing use of GLP-1 agonists is uncovering clues about what else they can do.
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Antonio Regalado @antonioregalado.bsky.social · 17/12/2024
Our annual list of the worst technology failures, flimflams and foul ups is live The winners are: -Google Woke AI -Boeing Starliner -Crowdstrike Outage -Vertical Farms -Exploding Pagers -23andMe -AI Slop -Voluntary Carbon Markets www.technologyreview.com/2024/12/17/1...
technologyreview.com
The 8 worst technology failures of 2024
Vertical farms, woke AI, and 23andMe made our annual list of failed tech.
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Antonio Regalado @antonioregalado.bsky.social · 05/12/2024
remember Biden's cancer moonshot? what ever happened to that
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Antonio Regalado @antonioregalado.bsky.social · 25/11/2024
Quite a story here about an IVF clinic mixup. Do you trade the baby you carried and cuddled for your biological child? www.nytimes.com/2024/11/25/m...
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Antonio Regalado @antonioregalado.bsky.social · 22/11/2024
Technology Review reports on "10 Years of Womb Transplants: What Have We Learned?" The oldest person gestated in a transplanted womb is now 10 years old. Overall, about 50 births from ~135 womb transplants. www.technologyreview.com/2024/11/22/1...
technologyreview.com
Who should get a uterus transplant? Experts aren’t sure.
Around 135 transplants have been performed, but it's probably too soon to offer the procedure to trans women.
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Antonio Regalado @antonioregalado.bsky.social · 21/11/2024
Seeking candidates for TR's infamous list of the "Worst" technologies of the year!!! Looking for tech that blew up, flopped in the market, or that we just love to hate. Extra points if failure holds a lesson. What are you picks? Please give me some ideas in replies 👇. All areas of technology.
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Antonio Regalado @antonioregalado.bsky.social · 15/11/2024
In this post, Robert F. Kennedy signaled several of his contrarian medical takes. Vis a vis "stem cells" he is referring to a range of unproven injections that the FDA sometimes cracks down on. As far as anyone knows, these treatments raise health expenditures for no improvement in health.
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Antonio Regalado @antonioregalado.bsky.social · 13/11/2024
A picture of notched and polished eagle talons retrieved from a Neanderthal site in Croatia, and ChatGPT's rendering of a Neanderthal wearing a necklace made from eagle talons.
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Matthew Herper @matthewherper.bsky.social · 12/11/2024
The end of 23andMe’s drug discovery dream. www.statnews.com/2024/11/11/2...
statnews.com
The end of 23andMe’s drug discovery dream
23andMe, the genetics startup that has repeatedly captured the public imagination and then faced nearly fatal business challenges, announced it would lay off 40% of its workforce.
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Michel Nivard @michelnivard.bsky.social · 11/11/2024
I LOVE the starter packs getting more and more niche “biology pack” -> “cellular biology” -> “organelle biology” -> “mitochondria pack” -> “mammalian mitochondrial evolution studies in Northern Europe on a Wednesday pack”
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Antonio Regalado @antonioregalado.bsky.social · 11/11/2024
As soon as they pass organoid testing !?#47^%!!
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