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Antonio Regalado

@antonioregalado.bsky.social
3K followers 558 following 154 posts

Biotechnology reporter for MIT Technology Review. Scoops about new methods. 'Playing God' beat. Gene editing, gene therapy, ancient DNA, synthetic embryos, cloning.

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Reposted by Antonio Regalado
Geoff Brumfiel @gbrumfiel.bsky.social · 30/03/2026
Okay this @antonioregalado.bsky.social story is hands down the most insane thing I’ve read this year. And 2026 has been WILD! www.technologyreview.com/2026/03/30/1...
technologyreview.com
Inside the stealthy startup that pitched brainless human clones
The ultimate plan to live forever is a brand new body.
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Reposted by Antonio Regalado
Rachel Courtland @rachelcourtland.com · 15/10/2026
For our Impossible issue, @antonioregalado.bsky.social took on the most mental of subjects. Head transplants, uploads, brains in jars, and more. ter.li/ihzd61a3
ter.li
Six wild ideas for perpetuating your mind
The quest for cognitive immortality continues.
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Antonio Regalado @antonioregalado.bsky.social · 10/12/2025
Have a smarter baby? You might, but it's not necessarily legal to advertise. Our look at the NYC subway ad campaign by IVF embryo profiling company Nucleus and how it collides with anti-discrimination statutes that apply to advertising on public property. www.technologyreview.com/2025/12/05/1...
technologyreview.com
The ads that sell the sizzle of genetic trait discrimination
A startup’s ads for controversial embryo tests hit the New York City subway.
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Antonio Regalado @antonioregalado.bsky.social · 04/12/2025
yeah. Several topics on which Grok argues forcefully from evidence that isn't great.
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Antonio Regalado @antonioregalado.bsky.social · 04/12/2025
Thanks for making the case. You are right it's a perennial candidate, but the Presidential sh*t coin takes it extra. What's the best factual coverage you've seen?
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Antonio Regalado @antonioregalado.bsky.social · 04/12/2025
lol. great.
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Antonio Regalado @antonioregalado.bsky.social · 04/12/2025
people are saying. but DOGE is not a technology per se. hard to shoehorn in, though Im open to ways
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Antonio Regalado @antonioregalado.bsky.social · 04/12/2025
Yeah, we had "AI Slop" on the list last year. I hate Google's AI suggestions in particular, but are they are failure or actually Google's bold and successful move to self-disrupt search.
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Antonio Regalado @antonioregalado.bsky.social · 04/12/2025
I am preparing MIT Technology Review's infamous list of "worst" technologies of the year. What are 2025's biggest failures, set backs, and misfires but which also hold useful lessons about technology? I think Cybertruck has to be on the list. Tell me your picks in the replies👇!!
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Antonio Regalado @antonioregalado.bsky.social · 25/11/2025
I think the matter at hand is not a prediction of ultimate IQ, but predicting which of two or more sibling embryos is likely to have higher IQ and by what degree.
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Antonio Regalado @antonioregalado.bsky.social · 10/11/2025
A month after Bari Weiss hired to lead CBS News division, heretic eugenics philosopher Jonathan Anomaly is on the morning show pitching bell curves and embryo scores. www.youtube.com/watch?v=qvVM...
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Reposted by Antonio Regalado
Adrian Woolfson @adrianwoolfson.bsky.social · 10/11/2025
I tremendously enjoyed Matthew Cobb’s definitive new biography of Crick. It was hard to put down and provides many new perspectives. My review of it will appear in Science later this week.
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Reposted by Antonio Regalado
Hank Greely @hankgreely.bsky.social · 04/11/2025
A 3rd (?) germline editing co announced @antonioregalado.bsky.social in @technologyreview.com, www.technologyreview.com/2025/10/31/1... I mainly share Fyodor's reaction, quoted in story—"In his email, Urnov said the launch of still another venture into the area made him want to “howl with pain.”
technologyreview.com
Here’s the latest company planning for gene-edited babies
Entrepreneurs say it’s time to safety-test designer baby technology.
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Reposted by Antonio Regalado
Jason Moore @moorejh.bsky.social · 21/10/2025
#password
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Antonio Regalado @antonioregalado.bsky.social · 21/10/2025
Here's an archived copy of his article that gets you past the paywall. web.archive.org/web/20251021...
web.archive.org
The astonishing embryo models of Jacob Hanna
Scientists are creating the beginnings of bodies without sperm or eggs. How far should they be allowed to go?
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Antonio Regalado @antonioregalado.bsky.social · 21/10/2025
The astonishing science of synthetic embryology and our profile of it's most ambitious praticioner, Jacob Hanna www.technologyreview.com/2025/10/21/1...
technologyreview.com
The astonishing embryo models of Jacob Hanna
Scientists are creating the beginnings of bodies without sperm or eggs. How far should they be allowed to go?
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Antonio Regalado @antonioregalado.bsky.social · 06/10/2025
Read this item by TB researcher whose grant got cancelled as 'dangerous gain of function.' Ironic, because the administration (RFK), has promoted whole‑virus vaccines, whose development, especially if they are attenuated, probably relies on very similar techniques.
hhs.gov
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Antonio Regalado @antonioregalado.bsky.social · 29/09/2025
69.97% certain he's referencing something he heard from people with relevant expertise. IVF clinics have nothing if not aneuploid embryos at hand.
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Antonio Regalado @antonioregalado.bsky.social · 29/09/2025
anyway, FYI, here is a person will billions in crypto proposing something (unspecified) about trisomy KO on the other site.
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Antonio Regalado @antonioregalado.bsky.social · 29/09/2025
Right. I am not sure of the tactic, but you can see it's interesting to strategize how to get rid of a trisomy.
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Antonio Regalado @antonioregalado.bsky.social · 25/09/2025
I see the figures thanks for the link.
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Antonio Regalado @antonioregalado.bsky.social · 25/09/2025
My q has been: i rob(14;21) such as case? Based on the chart seems like if a carrier generated many embryos some would be unaffected?
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Antonio Regalado @antonioregalado.bsky.social · 25/09/2025
cool. evo theory. These robs are a potential target of CRISPR. Use it to shred the extra bit (in zygote i guess). Some seek a situation/justification where germline editing would be *necessary* to obtain a healthy embryo (i.e. can't be done via embryo selection).
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Antonio Regalado @antonioregalado.bsky.social · 24/09/2025
thanks for posting. this is a very confusing phenomenon
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Antonio Regalado @antonioregalado.bsky.social · 17/09/2025
Here come the first "generative" genomes. Folks at the Arc Institute used an AI trained on DNA sequence to propose code for novel bacteriophage genomes. Of the 302 they synthesized, 16 actually worked--replicating and killing E. Coli. www.technologyreview.com/2025/09/17/1...
technologyreview.com
AI-designed viruses are here and already killing bacteria
Can AI create a life form? These “generative” genomes are a start
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Reposted by Antonio Regalado
Niall Firth @niallfirth.bsky.social · 17/09/2025
Can AI create a life form? These "generative" genomes are a start. New from @antonioregalado.bsky.social www.technologyreview.com/2025/09/17/1...
technologyreview.com
AI-designed viruses are here and already killing bacteria
Can AI create a life form? These "generative" genomes are a start
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Reposted by Antonio Regalado
Dr. D Boulware, MD MPH @drboulware.bsky.social · 24/06/2025
Can anyone find a Berman MF et al. Neurotoxicology 2008; 29(5), 914–922 ? This is a fake citation. www.sciencedirect.com/journal/neur...
sciencedirect.com
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Antonio Regalado @antonioregalado.bsky.social · 10/06/2025
yeah. thanks. it does sound like that is what she is saying.
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Antonio Regalado @antonioregalado.bsky.social · 10/06/2025
can you point me to where she makes this claim made? thanks. just want to see the source because..interesting if true.
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Antonio Regalado @antonioregalado.bsky.social · 09/06/2025
how do you know Musk employed gender selection.
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Antonio Regalado @antonioregalado.bsky.social · 06/06/2025
World famous synthetic embryo scientist stopped while entering U.S. Agent: Any embryos in your luggage? Scientist: One sec. [Opens guideline booklet of the International Society for Stem Cell Research.] Scientist: Nope, just 3-D structures derived from pluripotent stem cells.
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Antonio Regalado @antonioregalado.bsky.social · 06/06/2025
I call it business-casual eugenics
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Antonio Regalado @antonioregalado.bsky.social · 06/06/2025
glenn cohen commented recently that rules like that in the rider are surpassingly difficult to change. he presented at the "Observatory" meeting with a live reading of the rider. It was the first time I really appreciated it.
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Antonio Regalado @antonioregalado.bsky.social · 05/06/2025
For example, just this year an SEC lawsuit against Coinbase--for trading unregistered securities--was dismissed, reflecting a favorable re-assessment of crypto, from crime coin to real money. Similarly, online gambling + marijuana. from illegal to legal CRISPR babies next?
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Antonio Regalado @antonioregalado.bsky.social · 05/06/2025
Coinbase CEO, net worth ~$10B, wants to start definitive embryo editing company in the US. Making a gene-edit baby is prohibited in most of the world. But the winds can change. www.technologyreview.com/2025/06/05/1...
technologyreview.com
Crypto billionaire Brian Armstrong is ready to invest in CRISPR baby tech
The stigmatized idea could get a massive boost from “tech bros”—and some scientists are cheering them on.
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Antonio Regalado @antonioregalado.bsky.social · 29/05/2025
good one.
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Antonio Regalado @antonioregalado.bsky.social · 29/05/2025
OMG. Government "Make America Healthy Again" report has references to non-existent papers, suggesting US medical policy is partly plagiarized AI slop. Calling on author, NIH director @drjbhattacharya.bsky.social‬ to issue correction + investigate AI plagiarism www.notus.org/health-scien...
notus.org
The MAHA Report Cites Studies That Don’t Exist
The Trump administration’s “Make America Healthy Again” report misinterprets some studies and cites others that don’t exist, according to the listed authors.
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Antonio Regalado @antonioregalado.bsky.social · 27/05/2025
Japanese company to remove anachronisms from corporate names. What other companies have anachronisms in their names or logos?
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Reposted by Antonio Regalado
Cathy Gao-Howard MD MS @catgaohow.bsky.social · 18/05/2025
Northwestern has not received any NIH funds since March. No written communication about why or what can be done. Thank you Ben Singer for raising awareness at #ATS2025
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Antonio Regalado @antonioregalado.bsky.social · 07/05/2025
This individual has a "voice clone" that reads text in his voice. It is a subscription service from Eleven Labs. So it's possible if he doesnt pay he cant use "his" voice. Further, there are Terms & Conditions. You can't use the voice to say naughty things.
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Antonio Regalado @antonioregalado.bsky.social · 07/05/2025
Patient was posting from a Musk implant, with the help of Musk's AI, on a Musk media platform and in reply to a Musk fanboy, if not actually the “alt” of the richest person in the world. So it’s fair to ask: Where does patient end and Musk’s ecosystem begin? www.technologyreview.com/2025/05/07/1...
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Antonio Regalado @antonioregalado.bsky.social · 01/05/2025
Too lazy to clone the whole thread over from Musk's site. If you want to read about pig eugenics tho... x.com/antonioregal...
x.com
Antonio Regalado on X: "These pigs were produced using CRISPR to knock out the receptor for the virus, known as PRRS. This is your basic "CRISPR babies" strategy except applied to porkers." / X
These pigs were produced using CRISPR to knock out the receptor for the virus, known as PRRS. This is your basic "CRISPR babies" strategy except applied to porkers.
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Antonio Regalado @antonioregalado.bsky.social · 01/05/2025
This is pig. I mean big. FDA approves gene-edited pig resistant to common swine virus. more 👇https://www.pig-world.co.uk/news/pic-receives-us-approval-for-gene-edited-prrs-resistant-pigs.html
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Antonio Regalado @antonioregalado.bsky.social · 16/04/2025
Trademarks on Mamice, Mammouse, Woolly Mouse, Tassie (i.e. a thylacine), and Colossal. They could certainly trademark Dire wolf in a field of use or covering a particular font/design. There are several Dire Wolf trademarks from other people already.
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Antonio Regalado @antonioregalado.bsky.social · 16/04/2025
They trademarked "Woolly Mouse"
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Antonio Regalado @antonioregalado.bsky.social · 16/04/2025
my favorites are those hiding in plain sight, if only we have eyes to see them.
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Antonio Regalado @antonioregalado.bsky.social · 16/04/2025
bsky.app/profile/anto...
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Antonio Regalado @antonioregalado.bsky.social · 16/04/2025
Let biotechnology bring forth mammoths™ and birds™ and beasts™ of every kind. And it was so.
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Antonio Regalado @antonioregalado.bsky.social · 16/04/2025
Good kicker
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Antonio Regalado @antonioregalado.bsky.social · 16/04/2025
Here is the patent application discussed in this item. It was published in October 2024 but went uncommented upon. example claim "21. A transgenic animal comprising at least one woolly mammoth (Mammuthus primigenius) gene variant." patents.google.com/patent/WO202...
patents.google.com
WO2024211655A1 - Woolly mammoth specific gene variants and compositions comprising same - Google Patents
Provided herein are isolated nucleic acids, vectors, recombinant cells, and transgenic animals capable of expressing at least one or more woolly mammoth genes. Also provided are recombinant cells and ...
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