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Anneke Lucassen

@alucassen.bsky.social
823 followers 594 following 131 posts

Prof Genomic Medicine, UoOxford Director Centre for Personalised Medicine cpm.ox.ac.uk Interested in how we bring together ethics, social, molecular and clinical sciences to make sense of genomics. @annekeluc at the other place

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Anneke Lucassen @alucassen.bsky.social · 29/04/2026
What a spectacular tour de force this lecture was. Thankyou Trish for interesting and entertaining lecture highlighting how personalised medicine and personalised care must be considered together and that technologies are only useful if we retain context around data 1/2
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Rachel Horton @rachel-horton.bsky.social · 26/03/2026
This is such a brilliant and creative entry, I love the concept of people trying to see each other through layers of data
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Centre for Personalised Medicine @cpmoxford.bsky.social · 02/04/2026
A huge well done to Nyah! And thank you to everyone who entered and supported the competition this year. You can check out all of the finalists here: cpm.ox.ac.uk/centre-for-p...
cpm.ox.ac.uk
Centre for Personalised Medicine Art Competition 2025-26 - cpm
Earlier this year, the CPM ran an art competition asking UK students in Years 7 to 9 (approx. 11 to 14 years old) to send in art exploring the meaning of ‘personalised medicine’ and showing us what it...
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Centre for Personalised Medicine @cpmoxford.bsky.social · 13/04/2026
We're pleased to invite you to our 2026 Research Showcase - 'New Frontiers in Personalised Medicine' 🗓️ Wednesday 3rd June 2026 📍 St Anne's College, University of Oxford Find out more and register here: cpm.ox.ac.uk/event/resear...
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Centre for Personalised Medicine @cpmoxford.bsky.social · 23/04/2026
A huge well done to Ottilie! And thank you to everyone who entered and supported the competition this year. You can check out all of the finalists here: cpm.ox.ac.uk/centre-for-p...
cpm.ox.ac.uk
Centre for Personalised Medicine Art Competition 2025-26 - cpm
Earlier this year, the CPM ran an art competition asking UK students in Years 7 to 9 (approx. 11 to 14 years old) to send in art exploring the meaning of ‘personalised medicine’ and showing us what it...
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THIS Institute (The Healthcare Improvement Studies Institute) @thisinstitute.cam.ac.uk · 19/01/2026
There needs to be more clarity about what the #NHS10YearPlan offers for patients and what “good enough” looks like in terms of access, along with careful co-design and evaluation of the detail of each of the three shifts. Full paper: ths.im/4b6oPWp THIS Summary: ths.im/49oDU4k
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Heidi MacDonald @ SPX @comixace.bsky.social · 19/01/2026
Maybe we should stick to a message this simple.
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Centre for Personalised Medicine @cpmoxford.bsky.social · 19/01/2026
We’re delighted to announce that Professor Trish Greenhalgh @trishgreenhalgh.bsky.social will deliver this year’s CPM Annual Lecture, 'Personalised Medicine: A Primary Care Perspective' 🗓 28 April 2026 | 📍 Maths Institute, Oxford Find out more and register here: cpm.ox.ac.uk/event/cpm-an...
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Anneke Lucassen @alucassen.bsky.social · 14/01/2026
@emmylooroll.bsky.social said "Gene editing is absolutely a possibility, as is modifying downstream pathways. Genes aren’t all doom & gloom!🧬"
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Anneke Lucassen @alucassen.bsky.social · 14/01/2026
Yes for most of the population it will be modest, looking at the extremes of risk for a population doesnt tell you what the shift in probability would be with intervention for most.
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Anneke Lucassen @alucassen.bsky.social · 14/01/2026
Gene therapy in ~95% of the population is the naive concept here: manipulating the genomes of most people for only a modest shift in prob. This why, in public discussion, it is more appropriate to talk about genes as modifying risk alongside other factors, not singular “causes” to be edited away.
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Anneke Lucassen @alucassen.bsky.social · 13/01/2026
yep and as I said, fine in that setting- it was the press release I was responding to-'most alzheimer's cases linked to single gene' we lose the nuance that for 95% population carrying E3/E4, modifiable lifestyle factors remain the dominant lever for prevention.
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Anneke Lucassen @alucassen.bsky.social · 13/01/2026
Calling the most common human variant a 'risk allele' is methodologically correct but nosologically problematic—it redefines disease categorisation in a way that obscures rather than clarifies the distinction between genetic susceptibility and modifiable risk pathways.
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Centre for Personalised Medicine @cpmoxford.bsky.social · 02/12/2025
🧬 How well do ethnicity labels actually work in genomic medicine? Our new blog explores the challenges - and the pathways to more inclusive, meaningful data. ➡️ cpm.ox.ac.uk/thinking-out... #Genomics #HealthEquity #DiversityInResearch
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Centre for Personalised Medicine @cpmoxford.bsky.social · 05/01/2026
You can find out more about the competition and enjoy the amazing winning entries from previous years here: cpm.ox.ac.uk/art-and-scie...
cpm.ox.ac.uk
Arts & science connection - cpm
Centre for Personalised Medicine Art Competition Every year, we plan to ask young people to create art that looks at the great things and the challenging things about personalised medicine. This year,...
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Centre for Personalised Medicine @cpmoxford.bsky.social · 13/01/2026
Our 2024–25 Annual Report is now live! Reflecting on a year of collaboration, engagement, and impact at the CPM. Explore our flagship events, annual lectures, and creative outreach. ➡️ Read more here: cpm.ox.ac.uk/wp-content/u...
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Anneke Lucassen @alucassen.bsky.social · 13/01/2026
I think we're talking difference between "cause" in epidemiology and what pple understand in everyday speech. IMO "cause" misleads into thinking gene more deterministic than it is. for single dominant risk like smoking, "cause" is fine, but for multifactorial conditions "modifies risk" is better
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Anneke Lucassen @alucassen.bsky.social · 13/01/2026
I'm really looking forward to this. @CPM we have been fortunate to have absolutely stellar annual lecturers- see here for recordings of the last few years: cpm.ox.ac.uk/series/cpm-a... and @trishgreenhalgh.bsky.social will be no exception
cpm.ox.ac.uk
CPM Annual Lecture Series Archives - cpm
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Trish Greenhalgh @trishgreenhalgh.bsky.social · 13/01/2026
I'll be giving the Annual Guest Lecture for the Oxford Centre for Personalised Medicine. On 28th April 2026 at 5.30 pm. ‘Personalised Medicine, a Primary Care Perspective’. Open to all. cpm.ox.ac.uk/event/cpm-an...
cpm.ox.ac.uk
CPM Annual Lecture 2026 - cpm
We are delighted that the 2026 CPM Annual Lecture will be given by Professor Trish Greenhalgh; Personalised Medicine: A Primary Care Perspective. This will take place at the Maths Institute on Tuesday...
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Anneke Lucassen @alucassen.bsky.social · 13/01/2026
And 👏 to Honourable exception 🤭
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Anneke Lucassen @alucassen.bsky.social · 13/01/2026
Thanks for waking me out of bluesky inactivity! Presume this on the back of my SMC quote? My point was that if >95% population have a genotype, it is pretty meaningless to talk about it being causative of disease. Quite happy with apoE alleles *modifying risk* of Alzheimer’s
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Anneke Lucassen @alucassen.bsky.social · 13/11/2025
Brilliant! I did not know this paper so thanks from infrequent bluesky user for this nugget reposted.
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Hank Greely @hankgreely.bsky.social · 11/11/2025
Have you got a patent application in? Have you been to Sandhill Road in Palo Alto for funding? Why not??? BTW add the strong prediction that the kid will drink milk!
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Natalie Bennett @nataliegreenpeer.bsky.social · 10/11/2025
We get the politics the few pay for. #democracy - it would be a good idea www.theguardian.com/politics/202...
theguardian.com
Billionaire Tory donor gives £200,000 to Reform UK
JCB chair Lord Bamford hands equal amount to Tories and Reform to support parties he says ‘believe in small business’
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Bylines Network @bylinesnetwork.co.uk · 10/11/2025
Worried that using ChatGPT harms the planet? A new analysis shows each query uses less energy than a Google search – and far less than lighting a bulb or streaming TV. @eastangliabylines.co.uk
eastangliabylines.co.uk
How much energy does ChatGPT really use?
You shouldn’t really worry about your energy use when using domestic AI, it’s probably no worse than watching your favourite soap
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Michael Hobbes @michaelhobbes.bsky.social · 10/11/2025
“This thing is definitely bad for us but no one can say what it is”
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Anneke Lucassen @alucassen.bsky.social · 09/11/2025
Sounds very appealing: www.theguardian.com/lifeandstyle...
theguardian.com
She left her desk job and walked 3,541 miles from Mexico to Canada: ‘Give yourself permission’
Jessica Guo hiked 30 miles a day, becoming the first woman to continuously hike two historic US trails in a calendar year
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Kriszta Satori @fulelo.bsky.social · 06/11/2025
#BBCNews - Holocaust survivor and educator Manfred Goldberg dies aged 95 www.bbc.com/news/article...
bbc.com
Holocaust survivor and educator Manfred Goldberg dies aged 95
The German Jewish boy who saw his school closed by the Nazis dedicated his life to educating young people.
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Paul Fairie @paulisci.bsky.social · 06/11/2025
A List of Things Said to Have Been Ruined by Women 🧵
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Max Roser @maxroser.bsky.social · 06/11/2025
Over the last months, we’ve entirely rebuilt search on Our World in Data — we just launched it: ourworldindata.org/introducing-... Let me know what you think. Does it work for you?
ourworldindata.org
Introducing our new, more powerful search
Finding what you’re looking for, or discovering something new, has never been easier.
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LabLit.com @lablit.bsky.social · 06/11/2025
BBC vandalism, in an Age of Science to destroy the one science news programme left, after trivializing Science Now. These two programmes were once consecutive & complemented each other, treating listeners as adults.
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Christophe Veltsos @drinfosec.bsky.social · 06/11/2025
Sharing this 🎯 post from @barryhunt008.bsky.social over here: "Wow 🤩 Public Health messaging 100 years ago 👏👏👏"
[Alt text generated via Google Lens]
Do's and Don't's for Influenza Prevention.
(Douglas Island News.)
Wear a mask.
Live a clean, healthy life.
Keep the pores open that is bathe frequently.
Wash your hands before each meal.
Live in an abundance of fresh air, day and night.
Keep warm.
Get plenty of sleep.
Gargle frequently (and always after having been out) with a solution of salt in water (1/2 tsp for 8oz water). 
Report early symptoms to the doctor at once, Respect the quarantine regulations.
Avoid crowds. You can get the influenza only by -being near some one who is infected.
Avoid persons who sneeze or cough.
Do not neglect your mask.
Do not disregard the advice of a specialist just be-cause you do not understand.
Do not disregard the rights of a community obey cheerfully the rules issued by the authorities.
Do not think you are entitled to special privileges.
Do not go near other people if you have a cold or fever you may expose them to the influenza and death. See the doctor.
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Elizabeth Lanphier @ethicselizabeth.bsky.social · 06/11/2025
Sometimes I see a pre-print and pray to the science communication gods that it isn’t reported in the news as though it is a peer reviewed study.
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Trish Greenhalgh @trishgreenhalgh.bsky.social · 03/09/2025
Your periodic reminder that mRNA vaccines are a scientific and public health game-changer. Those that have been approved have passed stringent efficacy and safety checks. They protect you and your child against potentially fatal diseases. You may, however, get a sore arm.
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Bylines Network @bylinesnetwork.co.uk · 06/11/2025
Talent is everywhere, opportunity isn’t. In this letter to the editor, a former teacher reflects on her pupils’ hopes, and the barriers some will face ⤵️ @eastangliabylines.co.uk
eastangliabylines.co.uk
Letter to the editor: Every child’s ambition matters – whatever their background
A former teacher fears children’s dreams could be limited by prejudice and urges us to protect their potential
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Benjamin Riley @benjaminjriley.bsky.social · 06/11/2025
"LLMs are common-sense repositories. Yes, they can remix and recycle our knowledge in interesting ways. But they are trapped in the vocabularies we’ve encoded in our data and trained them upon. Large-language models are dead-metaphor machines." buildcognitiveresonance.substack.com/p/there-is-n...
buildcognitiveresonance.substack.com
There is no Artificial Irony
Large-language models are dead-metaphor machines
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IMS Epidemiology, University of Cambridge @imsepidemiology.bsky.social · 06/11/2025
Join our rescheduled online Bradford Hill Seminar with @alucassen.bsky.social, discussing: Diagnostic and predictive journeys: Finding the right balance in genomic medicine 📅 Wed 26 November, 1 PM (UK) Register buff.ly/U06QZ9N @dphpc.bsky.social @mrc-bsu.bsky.social @phgfoundation.bsky.social
Photo of Professor Anneke Lucassen, who will give a Bradford Hill Seminar on Wednesday  29 October, 1 PM (UK) discussing:

Diagnostic and predictive journeys: Finding the right balance in genomic medicine.
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Doug Parr @dougparr.bsky.social · 04/08/2025
Plastic is often seen as a cheap material but scientists in The Lancet argue it is expensive when including damage to health One estimate of the health damage from just three plastic chemicals – PBDE, BPA and DEHP – in 38 countries was $1.5tn a year. www.theguardian.com/environment/...
theguardian.com
World in $1.5tn ‘plastics crisis’ hitting health from infancy to old age, report warns
Plastic production has increased more than 200 times since 1950 and hits health at every stage from extraction to disposal, says review in the Lancet
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Chris Packham @chrisgpackham.bsky.social · 16/07/2025
Sheep are destroying precious British habitats – and we taxpayers are footing the bill to the tune of millions in a climate and biodiversity emergency - it’s bad and bonkers ! ⁦Me for The Guardian . . . @wildjustice.bsky.social www.theguardian.com/commentisfre...
theguardian.com
Sheep are destroying precious British habitats – and we taxpayers are footing the bill | Chris Packham
Large parts of Dartmoor have been denuded of wildlife, harmed by farming and a mess of government schemes that are costly in every way, says naturalist and broadcaster Chris Packham
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Anneke Lucassen @alucassen.bsky.social · 20/07/2025
Agreed, Brit soc genetic Medicine wrote a briefing on this: bsgm.org.uk/media/12702/...
bsgm.org.uk
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Helen Salisbury @helensalisbury.bsky.social · 19/07/2025
This this this Washing hands and wiping down surfaces will not do much to protect children from a deadly, highly infectious, airborne virus. Vaccinate and ventilate.
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Scientista @scientistas.bsky.social · 18/07/2025
In a world of polarized headlines, Katharine Hayhoe is cutting through the noise. She’s not just a top climate scientist — she’s showing how to talk about climate in ways that build trust, not division. 📰 Read more on Scientista:
scientista.substack.com
Katharine Hayhoe: Climate Communication that Works
The key to climate communication? Talk about what people already care about.
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Shane McKee @shaneir.bsky.social · 19/07/2025
Love this. Meanwhile can someone please hunt down whoever "Kiroe" is, and make it manifestly clear to them that their graffiti tag sucks and they're never to deface Belfast/Newtownabbey/Carrick ever again...
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Trish Greenhalgh @trishgreenhalgh.bsky.social · 19/07/2025
Greatly enjoying this book by a physicist turned sociologist explaining why you need more than the laws of physics to explain societal problems.
‘Everything is obvious’ by Duncan Watts
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Sasha Gusev @sashagusevposts.bsky.social · 19/07/2025
People often intuitively interpret genetic ancestry PCA plots as simple genetic distances, but this is not always the case. Below are random pairs of individuals that are far apart in PCA space (lines) but actually have fewer total variant differences (numbers).
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Penncat @pennicat.bsky.social · 18/07/2025
Email Yvette Cooper and tell her that the right to protest is part of any functioning democracy and if she wants to even pretend we’re that, she needs to stop preventing pretty much all protest the government doesn’t like. action.greenpeace.org.uk/e/854853/4lP...
action.greenpeace.org.uk
Yvette Cooper: Stop attacking the right to protest.
Tell the Home Secretary to repeal extreme anti-protest laws and protect our right to protest.
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hannah @hannahkateboast.bsky.social · 19/07/2025
Shaimaa has a scholarship to do a PhD on Palestinian literature with me at @uoe-llc.bsky.social, but she's stuck in Gaza because the foreign office won't help. Please share. www.telegraph.co.uk/world-news/2...
telegraph.co.uk
I should be at Cambridge, but I’m trapped in Gaza
Home Office red tape strands dozens of Palestinian scholarship winners in war zone
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Healthwatch @healthwatch.bsky.social · 20/07/2025
Good but remember more terminally ill die at home. So hospice at home services also need support. www.gov.uk/government/n...
gov.uk
£75 Million boost for hospices to transform end-of-life care
£75 million to modernise facilities and deliver upgrades to hospices across England including specially adapted beds, rooms, and technology.
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womensartbluesky.bsky.social @womensartbluesky.bsky.social · 20/07/2025
'Moonshine' by contemporary UK printmaker Janis Goodman #WomensArt
Print featuring a night scene with a central path through a wheat field leading to a hedgerow and tree under a full moon
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Paul Fairie @paulisci.bsky.social · 04/07/2025
AI is going to revolutionize everything
Image of Google AI overview
Yes, British websites use the term "biscuits" to refer to what Americans call "cookies". In the context of website usage, "cookies" refers to small pieces of data websites store on users' computers, not the baked treat. While some British websites might use "cookies" in this technical sense, the term "biscuits" is often used interchangeably with "cookies" for the digital data. 
Here's why:
British English vs. American English:
In British English, "biscuit" is the general term for what Americans call "cookies". 
Website Terminology:
Even though the technical term for website data is "cookies," some British websites might use "biscuits" to refer to them, especially when explaining the concept to users who might not be familiar with the technical term. 
Chocolate Chip Cookies:
The term "cookie" in the UK often refers specifically to chocolate chip cookies. 
Example:
A British website might say, "This website uses biscuits to improve your experience," meaning they use cookies for tracking and personalization.
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