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Reposted by Emma Anderson

Neil Davies @neilmdavies.bsky.social · 13/01/2026

The everyday understanding of cause and the epidemiological understanding of cause are similar. Virtually ubiquitous exposures can obviously have large contributions to disease in the population.

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Reposted by Emma Anderson

Emma Anderson @emmylooroll.bsky.social · 13/01/2026

Gene editing is absolutely a possibility, as is modifying downstream pathways. Genes aren’t all doom & gloom!🧬 The public don’t need patronising or protecting, they want to see that good science is being done and real progress is happening. Nice chatting Anneka, over & out! 😁 3/3

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Anneke Lucassen @alucassen.bsky.social · 13/01/2026

yep and as I said, fine in that setting- it was the press release I was responding to-'most alzheimer's cases linked to single gene' we lose the nuance that for 95% population carrying E3/E4, modifiable lifestyle factors remain the dominant lever for prevention.

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Reposted by Emma Anderson

Anneke Lucassen @alucassen.bsky.social · 13/01/2026

I think we're talking difference between "cause" in epidemiology and what pple understand in everyday speech. IMO "cause" misleads into thinking gene more deterministic than it is. for single dominant risk like smoking, "cause" is fine, but for multifactorial conditions "modifies risk" is better

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Dylan Williams @dylwil.bsky.social · 13/01/2026

My fave commentary on our paper in the Mail last week Interested to know what @alucassen.bsky.social uses as a definition of causation though! Here's mine: ajph.aphapublications.org/doi/full/10.... Further reading WRT the topic: zenodo.org/records/1796...

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Anneke Lucassen @alucassen.bsky.social · 13/01/2026

Thanks for waking me out of bluesky inactivity! Presume this on the back of my SMC quote? My point was that if >95% population have a genotype, it is pretty meaningless to talk about it being causative of disease. Quite happy with apoE alleles *modifying risk* of Alzheimer’s

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Dylan Williams @dylwil.bsky.social · 09/01/2026

Out now!! www.nature.com/articles/s44... Intro to this paper pictured below Huge thanks to collaborators @neilmdavies.bsky.social, @emmylooroll.bsky.social at @uclbrainscience.bsky.social & Sami Heikkinen and Mikko Hiltunen at @uniuef.bsky.social ... #endalz #episky #medsky

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Emma Anderson @emmylooroll.bsky.social · 08/09/2025

Last chance to sign up for our MR course next week folks!

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Emma Anderson @emmylooroll.bsky.social · 27/06/2025

New 29 month postdoc position available at Newcastle with Dr Oli Shannon for an exciting new project funded by ARUK 🥳 🔬 Investigating whether following UK-specific dietary guidelines is linked to lower dementia risk shorturl.at/6WZFd

shorturl.at

Research Assistant/Associate in Human Nutrition

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Emma Anderson @emmylooroll.bsky.social · 22/05/2025

Our in-person Mendelian randomisation course is back at University College London this autumn. Join us in Bloomsbury, 16th-18th September 2025. Tutors: Emma Anderson, Dylan Williams, Neil Davies Guest lecturer: Eleanor Sanderson onlinestore.ucl.ac.uk/conferences-...

onlinestore.ucl.ac.uk

D79 Mendelian Randomization | UCL Online Store

Abstract This course covers the fundamental developments in Mendelian randomization and gives practical explanations about how to apply MR to applied resea

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Dementia Researcher @dementiaresearcher.bsky.social · 30/06/2025

Postdoc in dementia research at Karolinska Institutet, Solna, with Dr Shireen Sindi and Prof Miia Kivipelto exploring sex differences and biomarkers in Alzheimer’s disease. Closing date: 6th July www.dementiaresearcher.nihr.ac.uk/job/karolins...

dementiaresearcher.nihr.ac.uk

Postdoctoral Researcher: Dementia Epidemiology

Postdoc in dementia research at Karolinska Institutet, Solna, with Dr Shireen Sindi & Prof Miia Kivipelto exploring sex differences & biomarkers in Alzheimer’s

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Emma Anderson @emmylooroll.bsky.social · 27/06/2025

shorturl.at

Research Assistant/Associate in Human Nutrition

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Emma Anderson @emmylooroll.bsky.social · 25/06/2025

Fabulous work by Phazha Bothongo! 2 years and several near mental breakdowns for us both in the making! 🧠 Causes and consequences of vascular dementia across the life course: Evidence from a UK Biobank phenome-wide and Mendelian randomization study 🧠 www.medrxiv.org/content/10.1...

medrxiv.org

Causes and consequences of vascular dementia across the life course: Evidence from a UK Biobank phenome-wide and Mendelian randomization study

Background Vascular dementia (VaD) is the second most common cause of dementia, yet its risk factors and biological mechanisms remain poorly understood. Objective To identify causes and consequences ...

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Emma Anderson @emmylooroll.bsky.social · 19/06/2025

Last couple of days to get your applications in folks!!

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Neil Davies @neilmdavies.bsky.social · 19/06/2025

Are you looking to learn how to conduct and interpret Mendelian randomization studies? You can register now for our in-person short course at UCL. With @emmylooroll.bsky.social and @dylwil.bsky.social 16th-18th September 2025. Details here: www.ucl.ac.uk/brain-scienc...

ucl.ac.uk

Mendelian randomization short course

This course covers the fundamental developments in Mendelian randomization and gives practical explanations about how to apply MR to applied research questions.

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Emma Anderson @emmylooroll.bsky.social · 11/06/2025

External link live! Please share widely :-) WE ARE RECRUITING! 🥳 Are you an epidemiologist with strong quantitative skills and an interest in contributing to exciting research into the genetic architecture of vascular dementia? Come join our friendly and productive team at UCL! shorturl.at/aZ5Ua

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Emma Anderson @emmylooroll.bsky.social · 30/05/2025

WE ARE RECRUITING! 🥳 Are you an epidemiologist with strong quantitative skills and an interest in contributing to exciting research into the genetic architecture of vascular dementia? Get in touch! We have an exciting opportunity to join our friendly and productive team at UCL. shorturl.at/fPbpv

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Emma Anderson @emmylooroll.bsky.social · 22/05/2025

onlinestore.ucl.ac.uk

D79 Mendelian Randomization | UCL Online Store

Abstract This course covers the fundamental developments in Mendelian randomization and gives practical explanations about how to apply MR to applied resea

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Emma Anderson @emmylooroll.bsky.social · 28/04/2025

Come join us! We had some great feedback last year and this year is set to be even better :-)

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Reposted by Emma Anderson

Dylan Williams @dylwil.bsky.social · 24/04/2025

Dislike this statement about AD by CARE programme grant invitation from @wellcomeleap.bsky.social and Lisa Mosconi. i) Commonplace misconception that "genetics = unmodifiable"... #episky #medsky

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Emma Anderson @emmylooroll.bsky.social · 23/04/2025

*NEW PREPRINT* Awesome work by Victoria Taylor-Bateman examining the effects of 46 different lipid-lowering, antihypertensive and anti-inflammatory drug targets on risk of vascular dementia diagnosis and several neuroimaging biomarkers of cerebrovascular pathology. A thread :-) shorturl.at/ecCD0

shorturl.at

Repurposing drugs for the prevention of vascular dementia: Evidence from drug target Mendelian randomization

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Emma Anderson @emmylooroll.bsky.social · 22/04/2025

Awesome work by Dylan and a REALLY important message

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Reposted by Emma Anderson

Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 19/02/2025

RFK Jr. thinks that a clinical trial should be done for the entire childhood vaccine schedule. Here’s why that will never happen. 1. You can’t do a randomized trial of something that we already know is safe and effective. There would have to be a placebo group that didn’t get vaxxed. Unethical.

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Emma Anderson @emmylooroll.bsky.social · 13/02/2025

Wow, it's like 'The Good Place' but for Twitter! 😀

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