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Alan Grossfield

@agrossfield.bsky.social
1.7K followers 1.3K following 1.9K posts

Expert in biomolecular simulation and biophysics. grossfieldlab.org github.com/agrossfield/wham grossfieldlab.github.io/loos orcid.org/0000-0002-5877-2789

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Alan Grossfield @agrossfield.bsky.social · 14h
This is what I was about to say — the means show a good trend, but the width of the distributions (roughly the same for all estimated levels? seems weird) says self-assessment isn’t very predictive for any given individual
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Alan Grossfield @agrossfield.bsky.social · 17h
Well done, those forms are a serious PITA
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Colette Delawalla, PhD @cdelawalla.bsky.social · 18h
SIGN THE PETITION DEMANDING CONGRESS STOPS OUR TAX DOLLARS FROM BEING USED TO EXPERIMENT ON AFRICAN BABIES HERE: www.standupforscience.net/petition-to-... And then share with everyone you know! We are pulling *every lever* to stop the “study”.
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Alan Grossfield @agrossfield.bsky.social · 19h
I hear Four Seasons is hiring…
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Alan Grossfield @agrossfield.bsky.social · 11/10/2026
I’ve always liked “I hope my email doesn’t find you – I hope you’re free.”
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Valentin Rodionov @arbitraryeffect.bsky.social · 10/10/2026
No, AI will not scoop your science. 93% of the time, frontier models cannot tell real science from "biofields" and cold fusion. We measured it. intellicat.ai/traces/index...
intellicat.ai
AI Models + Bad Science
We tested 30 leading AI models on 42 unreliable papers. They went along with the bad premise 93% of the time.
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Alan Grossfield @agrossfield.bsky.social · 09/10/2026
Ok, *that* sounds awesome (if a bit of overkill for a 3.5 league match)
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Alan Grossfield @agrossfield.bsky.social · 09/10/2026
That would be cool. I’m more concerned I’ll play badly in my usta match on Sunday.
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Alan Grossfield @agrossfield.bsky.social · 09/10/2026
Three vaccines this morning (Covid, flu, pneumonia). Here’s hoping they don’t make me feel too lousy this weekend.
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Alan Grossfield @agrossfield.bsky.social · 09/10/2026
Setting aside how good this must feel for you, it’s also a good experience for the reviewer — realizing the authors took your suggestions seriously, and knowing you helped make a good paper better.
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Alan Grossfield @agrossfield.bsky.social · 09/10/2026
By BPJ do you mean Biophysical Journal?
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Alan Grossfield @agrossfield.bsky.social · 09/10/2026
I think it’s worse than that — he simply doesn’t care whether what he says is true, and he’s explicitly admitted it, I think when he got caught lying about immigrants in Ohio. That story should be attached every time he’s quoted — he told reporters he has no problem lying if it makes his point.
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Patrick van der Wel @pcavanderwel.bsky.social · 04/10/2026
Looking forward to tomorrow’s NWO #Biophysics symposium, and especially also @kaytrue.bsky.social keynote lecture: “Two extremes of liquid-liquid phase separation in membranes: minimal, artificial membranes with two lipids versus living, biological membranes with hundreds of components” #LLPS ..
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Alan Grossfield @agrossfield.bsky.social · 03/10/2026
I presented those two papers in a journal club when I was in grad school. Little did I know the author would end up a friend!
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Alan Grossfield @agrossfield.bsky.social · 02/10/2026
Thought you might be. I’ve only met her once and very briefly, but based on her posts, she seems worth celebrating
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Alan Grossfield @agrossfield.bsky.social · 02/10/2026
Great example — I just saw one of these from @drstarbird.bsky.social
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Alan Grossfield @agrossfield.bsky.social · 02/10/2026
Congrats! First paper from the lab is a huge step!
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Chrystal Starbird @drstarbird.bsky.social · 01/10/2026
And… I am SO excited to share the first research preprint from my group! In this paper we determined several cryoEM structures to visualize the entire cell-to-cell bridging complex formed by TAM receptor and ligand, bringing into 3D a common graphical depiction. www.biorxiv.org/content/10.6...
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Biophysical Journal @biophysj.bsky.social · 29/09/2026
Special issue call for papers: The Past, Present, and Future of Muscle Biophysics. buff.ly/LDBUW2Z
biophysics.org
https://www.biophysics.org/Portals/0/BPSAssets/Publications/Documents/BJ_CallForPapers_MuscleBiophysics.pdf#Page=1
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Courtney Milan @courtneymilan.com · 28/09/2026
As an affirmed dog lover, I have a few things to say. (1) Dogs are harder than people admit. They take a lot of work. They need constant exercise and mental stimulation, especially those with working dog heritage of any kind. Dogs are hard.
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Jason Rasgon @vectorgen.bsky.social · 26/09/2026
Oh, are we posting Bad Faculty Job Interview stories again? Here's my contribution bsky.app/profile/vect...
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Kate Clancy @kateclancy.bsky.social · 22/09/2026
The anti-abortion crowd gets why this book is a threat (and are writing badly about it). Would love to see the pro-abortion crowd take the evidence, arguments, and perspective of this book and use it in their work!
bookshop.org
Pregnancy Interrupted: The Science and Stories of How Pregnancies Really End
A compassionate, evidence-based look at pregnancy loss--how and why it happens, and why the assurances of the medical industry don't reflect the reality One of the most prevalent myths about human pre...
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Alan Grossfield @agrossfield.bsky.social · 21/09/2026
The mythical man month?
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Martin Pacesa @martinpacesa.bsky.social · 21/09/2026
ʙɪɴᴅᴄʀᴀꜰᴛ2 is out, and we're not waiting for the paper. The full code drops today, free for academic and industry use. We're releasing it early so you can start designing right now, and bring its full power to the current Adaptyv competition. github.com/PacesaLab/Bi...
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ACLU @aclu.org · 16/09/2026
BREAKING: We're suing Secretary Robert F. Kennedy, Jr. and the National Institutes of Health Director for their ideologically-driven termination and censorship of biomedical research grants. Targeting views the government disagrees with for not aligning with a political agenda is unconstitutional.
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Stand Up for Science! @standupforscience.net · 14/09/2026
Russell Vought, head of OMB and a key author of Project 2025, has put forward a proposal that will put ALL FEDERAL GRANT FUNDING in the hands of Trump's political appointees. They will only fund what "demonstrably advances the President's policy priorities". Tell MoCs to stop it: tr.ee/D8Bj25 🧵
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Elisa Fadda @elisafadda.bsky.social · 14/09/2026
🚨 Want to be part of top #glycotime on the seaside in the California sunshine? Register to the 2027 GRC Glycobiology ⬇️ Stacy and Lance put togteher up one of the most exciting programmes I have ever seen with phenomenal keynotes! We have 32 abstracts to select, so the next speaker could be YOU! 😎
Announcement of the GRC Glycobiology 2027 to be held in Ventura CA on March 14 to 19, 2027. Blue background with an photo of Ventura from the visitventuraca.com
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Stand Up for Science! @standupforscience.net · 14/09/2026
There's A LOT of ways the Trump admin is currently attacking & decimating American science. Here's a breakdown of what they are doing, and what you can do about it. 🧵
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chipotlab.bsky.social @chipotlab.bsky.social · 10/09/2026
No predefined reaction coordinate. No mechanistic guesswork. No massive sampling campaign. Gen-COMPAS reconstructs biomolecular transition pathways from endpoint structures alone. Protein folding, allostery, membrane transport. Now in Nature. @nature.com @springernature.com
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Alan Grossfield @agrossfield.bsky.social · 13/09/2026
I wonder if it’s a university-specific culture thing, but I haven’t had this problem, at least not with undergrads — the requests I get seem the same as they’ve always been, mostly thoughtful. Requests from high school students have gone up, though, but we’re discouraged from having them in lab.
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5 Calls @5calls.org · 11/09/2026
Hi don't use VoteSafe dot org Elon Musk created it to capture all your personal data for his pro-fascist super PAC
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Kevin M. Kruse @kevinmkruse.bsky.social · 08/09/2026
Jesus Christ, @bsky.app
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Kevin M. Kruse @kevinmkruse.bsky.social · 08/09/2026
Shout out to the librarians.

When I was a kid, I loved two things in particular – puzzles and reading. The puzzles came first, as we always seemed to have a giant jigsaw in progress on the dining room table. And I got into jumbles, word searches, rebuses, crosswords, and the rest as soon as I could read.
And as I read, I was drawn over and over again to stories about puzzles. We made regular trips to the Bellevue branch of the Nashville Public Library, where I began working my way through books that introduced me to big puzzles and the people solving big puzzles, people who I learned were loosely classified as "detectives."
And there were a lot! A massive collection of original Batman comics. Encyclopedia Brown and his western cousin, The Great Brain. The Hardy Boys and Nancy Drew. The Boxcar Children. The Westing Game. "Murders in the Rue Morgue" and then everything else Poe wrote. Every single Sherlock Holmes mystery, every single Agatha Christie one too. Countless more I can't even remember
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Jeremy Berg @jeremymberg.bsky.social · 07/09/2026
If you are ever feeling inclined to believe that NIH Director Bhattacharya has any core scientific beliefs, remember this... He criticized and eliminated pandemic preparedness and biodefence from the NIAID strategic plan (without any process). www.nature.com/articles/s41... 1/4
nature.com
The new vision from the National Institute of Allergy and Infectious Diseases (NIAID) - Nature Medicine
Preparing for tomorrow’s threats by enhancing our ability to help patients today.
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Elle Cordova @ellecordova.bsky.social · 03/09/2026
Rough Draft vs Final Draft
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Biophysical Society @biophysicalsoc.bsky.social · 02/09/2026
For the upcoming National Postdoc Appreciation Week, September 21–25, BPS is excited to launch Beauty in Biophysics, a new image contest celebrating the research, creativity, and unique visual perspectives of our postdoctoral community. www.biophysics.org/outreach/pos...
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Data Colada @datacolada.bsky.social · 02/09/2026
Colada[139] Artificial Deadlines Part 2 Evidence of fraud in the 25 year old gradesheet behind the key finding in an influential paper on deadlines and procrastination. datacolada.org/139
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Merriam-Webster @merriam-webster.com · 31/08/2026
macabre = “muh-KAHB” Worcestershire = “WOOSS-ter-sheer” omnipotent = “ahm-NI-puh-tunt” reticent = “RET-uh-sunt” epitome = “ih-PIT-uh-mee” myriad = "MEER-ee-ud" Never make fun of someone if they mispronounce a word. It means they learned it by reading.
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Markus Deserno @markusdeserno.bsky.social · 31/08/2026
📣 I am super thrilled to announce that during “Emerging Science Week” the MSAF subgroup of the Biophysical Society will run a webinar with three awesome speakers on “Lipids Feeling the World.” More info, including how you sign up, is contained in the ALT text of the image! Please share widely! 🧪
Lipids form the compartments that organize life. While doing so, they interact with an incredible variety of other molecules and supramolecular structures—things that touch the membrane on either side, are embedded inside, or simply want to get through. What are the chemical and biophysical principles that shape such interactions? How have biomembranes evolved to become such versatile interfaces to the world? In this webinar we will hear from three scientists who have examined questions of this kind from different directions, focusing on different molecules, and using different tools.

Speakers:

(1) Janice Robertson, Dept. of Biochemistry and Molecular Biophysics, Washington University St. Louis, USA 
(2) Luca Monticelli, Molecular Microbiology and Structural Biochemistry, INSERM, Lyon, France 
(3) Rumiana Dimova, Biophysics Lab, Max-Planck-Institute for Colloids and Interfaces, Potsdam, Germany 

Here’s the link to register:

https://my.biophysics.org/Events/Calendar-Of-Events/Meeting-Home-Page?meetingid=4ea7bbbf-b695-f111-8075-6045bdff16f4

Attention: you’ll be asked to sign in or create an account. That’s just to keep track and send you an access link. YOU WILL NOT HAVE TO BE OR BECOME A BPS MEMBER!
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Chad Loder @chadloder.dev · 28/08/2026
Texas has suspended over 1.2 million voter registrations. Many valid voters in Texas have found their voter registrations were somehow canceled when they checked. Check your registration here and fix it immediately - Texas doesn't always honor provisional ballots cast on election day.
goelect.txelections.civixapps.com
IvisMvpUi
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Prof Gavin Yamey MD MPH @gavinyamey.bsky.social · 26/08/2026
A study of over 4 million kids & young adults concludes that those who receive a Pfizer/Biotech COVID-19 mRNA vaccine have a lower risk of myocarditis, pericarditis, and death than those who do not
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Alan Grossfield @agrossfield.bsky.social · 14/08/2026
You can’t delete it, but you can turn it off, which is almost as good.
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Alan Grossfield @agrossfield.bsky.social · 12/08/2026
Food safety is the perfect example for Chesterton’s fence.
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Kate Clancy @kateclancy.bsky.social · 11/08/2026
Jesus fucking Christ covid vax REDUCED miscarriages and stillbirths. Also I'm one of the people who studied menstrual side fx of the covid vax to make sure we didn't invalidate peoples' real experiences, and to better set expectations for side fx. Ultimately the project made me even MORE provax!
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Alan Grossfield @agrossfield.bsky.social · 10/08/2026
Books are pretty much useless in bio areas — they take forever to come out and because there’s no institutional subscriptions, the odds say it’ll be totally inaccessible to the intended audience.
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Chemistry World @chemistryworld.com · 10/08/2026
A critical turning point came in 1865 when Clausius coined the word ‘entropy’ to label an issue which had concerned him for years – the fact that although energy cannot be created or destroyed, over time it becomes more dispersed and inevitably less available. www.chemistryworld.com/features/150...
chemistryworld.com
150 years of Gibbs’ phase rule
In 1873, Josiah Willard Gibbs published an equation that would transform chemistry - yet barely anyone noticed at the time. The story of his phase rule is one of delayed recognition, mathematical abst...
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Drug Monkey @drugmonkey.bsky.social · 08/08/2026
What I am most proactively angry about is that even if there is an after times, those who have been most injured / affected will be told to get to the back of the line and be happy with relative crumbs. While the “more important” things are fixed first.
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Alex @purplechrain.bsky.social · 06/08/2026
People angrily insisting that El-Sayed using the phrase “break bread” re: sharing a meal with Jews at Passover was ignorant or offensive or insincere is a peak combination of assholes going out of their way to find something to get angry about & some Jews having weird illiteracy about Judaism.
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Alan Grossfield @agrossfield.bsky.social · 06/08/2026
This responsibility is the hardest thing about having a pet. They can’t tell you when they’re done, so you have to make a guess and live with the guilt, no matter what happens. The only thing I can say is that I’d rather do it a day too soon than a day too late.
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Alan Grossfield @agrossfield.bsky.social · 06/08/2026
You are incorrect. The key difference with the fed is that the interests of a politician (strong economic growth leading up to an election) often directly contradict what’s good for the economy (balancing growth and employment with moderate inflation). Independence for the fed is a special case.
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