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Pablo Ortiz

@313kidney.bsky.social
220 followers 309 following 9 posts

Renal Physiology , the kidney in hypertension, molecular mechanisms of cardiovascular disease, scientist , frustrated musician , happily living in Detroit (a miracle city!)

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Reposted by Pablo Ortiz
Joshua Weitz @joshuasweitz.bsky.social · 11/10/2026
The NIH proposal to conceal reviewer scores from program officers, investigators, and advisory councils is ill-conceived, introduces disproportionate weight to small percentile differences, diminishes the role of scientific peer review, and should be withdrawn in its entirety. a 🧵
joshuasweitz.substack.com
What is NIH Leadership Trying to Hide from Researchers & the Public?
A NIH proposal to conceal reviewer rankings of investigator-initiated research grants is ripe for misuse & demands a collective response (by October 13).
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Jenny Cohn @jennycohn.bsky.social · 02/10/2026
Argentina is about to be heavily colonized.
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Jonathan Howard @joho.bsky.social · 29/09/2026
In October 2020, Jay Bhattacharya looked into a camera and said he wanted to “let people face the risk of the disease.” Does his pro-virus advocacy merit inclusion amongst the giants of infectious disease prevention?
sciencebasedmedicine.org
Jay Bhattacharya October 2020: “Let People Face the Risk of the Disease.”
Dr. Jay Bhattacharya sought to spread a deadly pathogen. Does he belong in the HHS Hall of Heroes with legends who tried to contain them?
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Reposted by Pablo Ortiz
elizabethginexi.bsky.social @elizabethginexi.bsky.social · 23/09/2026
Advocacy works! But we must remain vigilant and be ready for more advocacy efforts in the future. www.semafor.com/article/09/2...
semafor.com
Exclusive: Trump administration backing off NIH grant order amid pushback
The proposal, which would have given President Donald Trump greater influence over health grant decisionmaking, could still advance in a new form.
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Reposted by Pablo Ortiz
American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 22/09/2026
NIH funding decisions should be made by scientific experts, not political appointees. Protecting rigorous peer review safeguards public trust, biomedical progress and U.S. scientific leadership. ➡️Learn more: www.asbmb.org/advocacy/pos... #ScienceServesUsAll #ASBMBAdvocates
Graphic reading "Science Serves Us All" over a blue scientific background with the ASBMB logo.
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American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 22/09/2026
📢 Make your voice heard. Contact your members of Congress today and urge them to ask the White House to withdraw its proposal for a board of political appointees with authority over NIH grant decisions. ➡️ Take action: asbmb.quorum.us/campaign/169... #ScienceServesUsAll #ASBMBAdvocates
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Reposted by Pablo Ortiz
STAT @statnews.com · 21/09/2026
“We should be strengthening our investment in the NIH, not dismantling it,” writes Reed Jobs. www.statnews.com/2026/09/21/n...
statnews.com
The NIH budget should be $100 billion per year
“We should be strengthening our investment in the NIH, not dismantling it,” writes Reed Jobs.
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Reposted by Pablo Ortiz
The Guardian @theguardian.com · 16/09/2026
New lawsuit accuses Trump administration of blocking NIH grants as form of censorship
theguardian.com
New lawsuit accuses Trump administration of blocking NIH grants as form of censorship
The administration has used a list of 235 keywords – such as ‘gender’ and ‘racist’ – to prevent topics from being funded
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Reposted by Pablo Ortiz
Journal of Clinical Investigation @jci.org · 10/09/2026
Take a look a the Commentary highlight by Brandilyn A. Peters: doi.org/10.1172/JCI2...
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Reposted by Pablo Ortiz
JAMA @jama.com · 28/08/2026
#MedNews: Under the updated AHA/ACC blood pressure guideline, nearly 1 in 3 adults with hypertension may be newly eligible for antihypertensive medication. Find out more about how expanding treatment could reduce mortality.
jamanetwork.com
Hypertension Widely Undertreated, New Study Suggests
This Medical News article discusses the estimated population-level effects of the 2025 blood pressure guideline, which expanded antihypertensive treatment eligibility.
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AAMC @aamc.org · 20/08/2026
NIH funding equates to $138 per American per year. And the return on investment is millions of lives saved. Read more about the extraordinary medical progress NIH funding supports: bit.ly/4i1ewX9
usatoday.com
How Biomedical Research Moves From a Lab Into Patient Care
Physicians work on both the research side and at the patient bedside, translating questions raised in clinical practice into rigorous scientific investigations and bringing those discoveries back to p...
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Reposted by Pablo Ortiz
Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 10/08/2026
NIH “Director” Jay Bhattacharya keeps talking about how he is going to restore trust in public health. So what has happened since he began his role on April 1, 2025? Trust in public health has *plummeted*. The rest of us would be fired for such poor performance. He is an absolute disgrace.
politico.com
NIH head quarrels with CBS host over loss in public trust on health issues
Jay Bhattacharya's interview ended up similar in tone to the one with Robert F. Kennedy Jr. last week on CNN.
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Jenna Norton @jenna-m-norton.bsky.social · 04/08/2026
RFK jr overrode the NIH recommendation for NIAID Director to appoint his own preferred candidate (who applied, but NIH declined to interview), per @politico.com. Institute directors have final say on funding decisions and are critical to the integrity of NIH. 🧵 www.politico.com/news/2026/08...
politico.com
A lab-leak proponent is in line for Fauci’s old job
Steven Quay is in final vetting to run the National Institute of Allergy and Infectious Diseases.
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Científico Latino @cientificolatino.com · 03/08/2026
Our Graduate School Mentorship Initiative (GSMI) started in 2019 when three graduate students had a vision to make graduate school entry accessible for students from low-income, first-generation and underserved communities. www.youtube.com/watch?v=s88T...
youtube.com
Científico Latino: Graduate School Mentorship Initiative (GSMI)
YouTube video by Científico Latino
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Lisa Needham @snipy.bsky.social · 30/07/2026
Oh hello, I wrote a gazillion words about Trump's proposed new golden age of science and how it is anything but.
open.substack.com
The new "science golden age" looks suspiciously like a grift
Trump wants to run scientific research like his family business.
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Reposted by Pablo Ortiz
Defend Public Health @defendpublichealth.bsky.social · 13/07/2026
Our own @elizabethjacobs.bsky.social in @sciam.bsky.social
scientificamerican.com
Scientists overwhelmingly against rule change that would give political appointees say over science grants
Hundreds of thousands of scientists, including Nobel laureates, warn that changes to the way federal grants are approved would greatly damage American science
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Tech Policy Press @techpolicypress.bsky.social · 13/07/2026
Using an open-source pipeline to read every comment on OMB's proposed grants rule that could have significant impact on science and technology research funding, Christopher Steven Marcum and Abigail Haddad find the verdict "clear and lopsided": ~94% oppose it.
buff.ly
The Public Rejects OMB's Federal Financial Assistance Rule
Tens of thousands of scientists, clinicians, and ordinary citizens warned OMB about putting political appointees in charge of which research gets funded.
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Karin Wulf @kawulf.bsky.social · 10/07/2026
Public conversation about the OMB proposal has focused on science, but make no mistake: this is about ALL research and humanities are just as vulnerable. I'm back @scholarlykitchen.bsky.social w historian & @historians.org exec director Sarah Weicksel. scholarlykitchen.sspnet.org/2026/07/10/t...
scholarlykitchen.sspnet.org
The OMB Guidance Revision Threatens All Research - The Scholarly Kitchen
The OMB proposed revision is about all research — and humanities research is just as vulnerable as STEM.
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Jeremy Berg @jeremymberg.bsky.social · 02/07/2026
Yes, these discoveries were subsequently used to develop drugs by private industry. That is how the biomedical research ecosystem almost always works. Discovery to Expansion/Refinement to Development 6/7
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Jeremy Berg @jeremymberg.bsky.social · 02/07/2026
Famously, a related peptide with a much longer biological half-life was discovered in gila monsters, in work first initiated in the intramural program at NIH. 5/7
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Jeremy Berg @jeremymberg.bsky.social · 02/07/2026
GLP-1 was discovered as a glucagon-like peptide encoded by preproglucagon in 1987 in research funded by NIH (NIDDK). Subsequent academic studies demonstrated that GLP-1 acts in an opposite manner than does glucagon, promoting lowering blood glucose level. 4/7
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Jeremy Berg @jeremymberg.bsky.social · 02/07/2026
Where does Atlas think information about the key molecules that led to checkpoint inhibitors can from? These molecules such as CTLA-4 were discovered from studies of basic immunology funded by NIH (NCI) 3/7
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Reposted by Pablo Ortiz
Jeremy Berg @jeremymberg.bsky.social · 02/07/2026
2/7
Private capital, not NIH direction, produced many of the most celebrated medical advances of the past two decades. Checkpoint inhibitors — drugs that allow the immune system to recognize and attack tumors it ignored — have converted metastatic melanoma, lung and kidney cancer from near-death sentences into more manageable conditions. These drugs reached patients through industry investment. Semaglutide, reshaping obesity treatment for tens of millions through drugs such as Ozempic and Wegovy, was developed by Novo Nordisk’s research chemists without NIH direction.
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Jeremy Berg @jeremymberg.bsky.social · 02/07/2026
Scott Atlas, the champion of herd immunity as an Fox News commenter and the Trump Advisor during COVID, weighs in with a DEEPLY MININFORMED op-ed in the WaPo. www.washingtonpost.com/opinions/202... 1/7
washingtonpost.com
Opinion | Abolish the NIH
A $48 billion government monopoly should give way to the market.
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Max Kozlov @maxkozlov.bsky.social · 27/06/2026
NIH grants have been under political scrutiny since early 2025. But what does the screening process actually look like? What is being flagged? I spent a month digging into leaked docs and emails. We've published the 235-word list that are being flagged by an internal AI tool. And so much more. 🧵
nature.com
Inside the new political screening that’s stalling NIH grants
Mandatory reviews by top health officials and checks for 235 disfavoured terms have left hundreds of vetted grant applications in administrative limbo.
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Drug Monkey @drugmonkey.bsky.social · 19/06/2026
"NIH aims to incentivize and reward rigorous research that delivers value to the American public, but current metrics of scientific success rely heavily on individual-level indicators of productivity, such as publication counts and citation metrics. " grants.nih.gov/grants/guide...
grants.nih.gov
NOT-OD-26-087: Request for Information on Measuring and Rewarding Scientific Impact
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Information on Measuring and Rewarding Scientific Impact NOT-OD-26-087. NIH
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Reposted by Pablo Ortiz
PKD Research Resource Consortium @pkdresearch.bsky.social · 18/06/2026
Did you miss the PKD RRC Monthly Scientific Roundtable for June 2026? No worries, the outstanding presentation by David M. Bedwell, Ph.D. Professor & Chair., Dept. of Biochemistry and Molecular Genetics at UAB, is now available at www.pkd-rrc.org/pkd-rrc-mont...
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Reposted by Pablo Ortiz
Jeremy Berg @jeremymberg.bsky.social · 17/06/2026
Powerful piece from two former NIH staffers www.insidehighered.com/opinion/view...
insidehighered.com
The 3-Pronged Attack on Scientific Communication (opinion)
At the NIH, political appointees exercise extensive control over scientific communication, and research on health communication is under siege.
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Michael D. Green, PhD @michaeldgreen.phd · 10/06/2026
Gave some comments for this story in @science.org about a study in JAMA that shows a devastating decrease in NIH fellowships awarded to Black and Hispanic scientists. A lot of early career people are having their future meddled with. Some groups unequally... www.science.org/content/arti...
science.org
Study finds sharp decline in Black, Hispanic researchers receiving NIH funding
Drop in those receiving grants and fellowships in 2025 shows impact of Trump administration rollbacks to diversity initiatives
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Science Magazine @science.org · 11/06/2026
The National Institutes of Health has returned to the idea that limiting lab size makes better use of grant dollars. scim.ag/4uZGBl9
scim.ag
NIH plans to cap number of grants a scientist can have at once
Agency is bringing back a version of a funding limit that was quickly abandoned nearly a decade ago
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Carl T. Bergstrom @carlbergstrom.com · 06/06/2026
Here's the article. diabetesjournals.org/care/article...
diabetesjournals.org
Misguided Brushes of a Pen Continue to Dismantle and Destroy Biomedical Research in the United States: We Can No Longer Afford Complacency and Fear. We Must All Act Now!
The opinions expressed in this editorial are the personal views of the authors (S.E. Kahn, C.A.M. Anderson, J.B. Buse, and E. Selvin) and do not represent
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Drug Monkey @drugmonkey.bsky.social · 09/06/2026
NIH seeks input on capping grant awards drugmonkey.wordpress.com/2026/06/09/n...
drugmonkey.wordpress.com
NIH seeks input on capping grant awards
The NIH has posted a request for input on a proposal to limit the number of grant awards a given PI may hold at any one time. NOT-OD-26-086 Request for Information: Proposal to Cap the Number of Si…
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Reposted by Pablo Ortiz
Carl T. Bergstrom @carlbergstrom.com · 06/06/2026
Remember the current NIH director going on about protecting researchers from government censorship? Today his people called the police in to forcibly remove my colleagues from their own society meeting for sharing an editorial published in their flagship journal that was critical of him. Gift link
nytimes.com
Police Remove Diabetes Experts From Conference for Distributing Critique of Trump Administration
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American Society for Cell Biology @ascbiology.bsky.social · 04/06/2026
Scientists: Your voice is needed. New federal regulations could reshape research funding, publishing, and collaboration. Comments close July 13. www.ascb.org/science-policy/propose…
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Reposted by Pablo Ortiz
Science Magazine @science.org · 01/06/2026
Exclusive: The Department of Health and Human Services is now recommending changes to peer-reviewed National Institutes of Health grants. scim.ag/3RXCs2l
scim.ag
Exclusive: HHS is now weighing in on science in NIH grants
Staffers say comments coming after NIH’s own approvals are overriding peer review
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American Society for Cell Biology @ascbiology.bsky.social · 01/06/2026
Sweeping draft regulations released by OMB pose one of the most significant threats to federally funded research in decades. The proposal would affect nearly every aspect of the scientific process. Read more: www.ascb.org/science-policy/federal…
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TK (Takashi DY) Kozai @bioniclab.bsky.social · 30/05/2026
🪼 Your tax dollars paid a scientist to squeeze jellyfish through cheesecloth. Osamu Shimomura processed tens of thousands on an NSF grant to understand why they glow. He found a protein that glowed green under UV light. Called it "green protein." Nobody cared. For decades.
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Timothy Burke @bubbaprog.xyz · 31/05/2026
and they called it a waste of tax dollars back then, too
CAPITAL CHATTER . . .  
By Don McLean  

WASHINGTON - On the same day that it was announced we will spend $2.2 million to study jellyfish in Chesapeake Bay it was announced also that we'll lay out only $22,000 to study student suicides.  

One's first impression might be that our government is 100 times more interested in jellyfish than it is in students. Of course, that's probably not true, but, in case it is, I have a suggestion: Since we're trying to eliminate jellyfish and sustain students, why not combine the two studies? Perhaps we can find a way to drive the jellyfish to suicide.  

In addition to the two government-sponsored studies mentioned above, there are a couple of other Federal research projects we should touch on. For instance, at this very moment we are transferring from the Federal Treasury to certain Icelandic scientists the sum of $32,000. This is for a study of the ptarmigan, a sort of game bird, and a subject about which I shall not grouse. After all, try to imagine a world without ptarmigans. Unthinkable.  

In looking over the list of government scientific interests, it is difficult to determine which it finds more fascinating - the backwardness or the progress of a people. For example, we are spending $9,573 to study "Family behavior and personality development in small isolated communities in mountain areas of Norway."  

On the other hand, we're spending only $25,765 to probe "The social problems associated with the rapid urbanization of Marsta," a village in Sweden. On the surface, it appears that we're three times more interested in the backwardness of Norway than we are in the progress of Sweden. But I think much of the Norwegian study money will be spent simply trying to FIND an isolated community to study.  
*Maclean dictionary: An isolated community is one surrounded by ice.*  

My favorite bit of research in the current list comes under the heading of "A study of the learning and memory processes of the large bilingual Estonian population of Toronto." This will cost us a trifling $48,000, although this probably makes us $48,700 more interested in the project than Canada itself is.  

It is obvious that the curiosity of our government is almost limitless. Except, I'm afraid, in the direction of space, where it's thinking of cutting expenditures. I presume this is so we can afford to study these other more worthwhile things. If only I could prove somehow that there are ptarmigans on the moon. NASA might have better luck with its appropriations.
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Chanda Prescod-Weinstein 🌌 @chanda.blacksky.app · 29/05/2026
In this newsletter I outline important actions to take. 1. Submit a comment opposing the rule change. 2. Contact state legislators to ensure states are engaged with the impact at the state and local level. 3. Contact members of Congress. 4. Spread awareness. This rundown is a great source:
open.substack.com
Summary of Key Changes in OMB’s Proposed Federal Financial Assistance Rule
Russell Vought is going to destroy American Science
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Jeremy Berg @jeremymberg.bsky.social · 30/05/2026
Several people have asked for possible content and structure for comments regarding the proposed OMB regulations. With some suggestions from others, I have posted on example (as a Word document) for downloading). jeremymberg.github.io/jeremyberg.g... I hope this is helpful.
jeremymberg.github.io
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Carl T. Bergstrom @carlbergstrom.com · 30/05/2026
While regulations.gov incorrectly lists this action as "closed for comments", you can submit your comments directly here: www.regulations.gov/commenton/OM... My response is below, but don't feel that you need to draft anything nearly so long-winded. A short statement will also be very helpful.
For the better part of a century, US science has been the envy of the world, propelled by Eisenhower-era investment in every level of research and education, up through and including the American research university system. The best and brightest from around the world have come to the United States to study and work. Some stayed, bringing their exceptional talent here; others returned home, often carrying with them professional norms, institutional ties, and democratic ideals encountered in the United States, a process that has been a critical form of US soft power for many decades. This vibrant ecosystem of science, technology, engineering, and medicine has led the US through its transformation from a manufacturing economy to a technology and information economy, and ensured US prosperity and economic power up to the present day. Our funding agencies have not only promoted the technological discoveries and medical breakthroughs that transform our world and extend our lives, but also have been instrumental in developing the human capital that flows into our commercial science and technology sector and generates the growth and innovation that has given US businesses a worldwide competitive advantage. 

These proposed changes to the Regulations for Federal Financial Assistance undercut all of this. By transferring decision-making authority from scientific experts to political appointees in the grantmaking process, we lose the competitive edge and innovative capacity provided by the most effective research funding system in history. The numerous provisions allowing administrators to exclude individuals and institutions based on political litmus tests serve to squander the diverse talent available in this country, undermine basic principles of free speech, and run counter to the very ethos of science as described by Robert Merton in 1942. 

Science costs money, and scientific research is planned out on the scale of years. When any grant can be terminated at any time for…
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Jeremy Berg @jeremymberg.bsky.social · 29/05/2026
Comments are now open. You can comment here: www.regulations.gov/search?filte... Note that even if the administration goes ahead with this abomination, the comments are essential to aid subsequent litigation! 2/2
static.klipy.com
Jordy's 'Just My Two Cents' on Breakfast TV
ALT: Jordy's 'Just My Two Cents' on Breakfast TV
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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 28/05/2026
The leadership and clarity of @MIT President Sally Kornbluth www.bostonglobe.com/2026/05/26/o...
bostonglobe.com
America built the world’s greatest research engine. Now it’s shrinking. - The Boston Globe
At public and private universities across the country, high-impact science is being damaged and derailed.
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NPR @npr.org · 21/05/2026
Even with federal grants largely restored, scientists say the Trump administration is still preventing those funds from reaching them. The consequences, they say, are already becoming clear. n.pr/4dwU7Fi
n.pr
Researchers say the Trump administration is finding new ways to punish science
Even with federal grants largely restored, scientists say the Trump administration is still preventing those funds from reaching them. The consequences, they say, are already becoming clear.
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Jenna Norton @jenna-m-norton.bsky.social · 18/05/2026
Bhattacharya often mischaracterizes multiyear funding as beneficial to early career scientists. In reality, it creates a hyper-competitive, resource constrained environment. Part 2 of @27unihted.bsky.social's fact check address MYF. 27unihted.substack.com/p/fact-check...
27unihted.substack.com
Fact Check, Part 2: NIH Director Conceals the Harmful Consequences of Multiyear Funding Transition
NIH Director Jay Bhattacharya oversells benefits, ignores harms from the rapid transition to multiyear funding during the March 17, 2026 House Appropriations Committee Hearing
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Philip N Cohen @philipncohen.com · 14/05/2026
Two new facts stand out: 1. 85% of hallucinated citations in preprints are also in the subsequent journal version (thanks, peer review!) 2. Fake cites more likely to use the names of (male) scholars who are already highly cited, creating a fake-citation Matthew effect. arxiv.org/abs/2605.07723
arxiv.org
LLM hallucinations in the wild: Large-scale evidence from non-existent citations
Large language models (LLMs) are known to generate plausible but false information across a wide range of contexts, yet the real-world magnitude and consequences of this hallucination problem remain p...
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Ames Grawert @amescg.bsky.social · 14/05/2026
Over the past year the Trump Administration has frozen, canceled, or slow-walked billions in funding for the sciences. We outline the dire consequences of those decisions — for the rule of law and the American economy. www.brennancenter.org/our-work/res...
brennancenter.org
The Cost of the Trump Administration’s Attacks on Research Funding
Arbitrary funding cuts and assaults on agency independence have destabilized American scientific research, potentially setting technology, health care, and the economy back decades.
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Science Magazine @science.org · 07/05/2026
#AI tools designed to execute end-to-end projects are increasingly popular with researchers—and increasingly skilled. But a new study shows these tools can stealthily violate norms of research integrity. Learn more: scim.ag/4dgqMit
AI agents may be skilled researchers—but not always honest ones
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Jeremy Berg @jeremymberg.bsky.social · 30/04/2026
New STAT story about the chances of receiving NIH funding www.statnews.com/2026/04/30/n... 1/3
statnews.com
Securing NIH awards is getting more competitive — and confusing
The likelihood of snagging NIH grants has plunged to historic lows, forcing academic researchers to resort to a variety of tactics to try to obtain funding
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Timothy McBride @mcbridetd.bsky.social · 26/04/2026
Federal Policy Changes and Career Stability Among NIH K-Award Recipients Among NIH K-award recipients, 96% perceived recent federal policy changes as negatively affecting research career stability; 18% report being much less likely to continue research vs 1 year ago jamanetwork.com/journals/jam...
jamanetwork.com
Federal Policy Changes and Career Stability Among NIH K-Award Recipients
This cross-sectional study uses survey data to evaluate how National Institutes of Health (NIH) K awardees perceive the effects of federal policy on research career stability and intentions to pursue ...
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