Bcl-2-associated athanogene 3 (BAG3) is a mediator of chaperone-assisted selective autophagy, and in the brain, is most highly expressed in astrocy...

Genetic studies implicate clusterin (CLU) in the pathogenesis of Alzheimer’s disease (AD), yet its precise molecular impact remains unclear. Through u…

American universities have given the country prosperity and security. The Trump administration’s attack on academic freedom endangers all of that.

Mitochondrial damage and dysfunction are hallmarks of neuronal injury during cerebral ischemia-reperfusion (I/R). Critical mitochondrial functions including energy production and cell signaling are...

Identifying a tumor’s molecular subtype during surgery and rapidly quantifying mutations in resected tissues intraoperatively could guide resection strategy and improve resections. Murphy, Bianchini, et al. introduce Ultra-Rapid droplet digital PCR, which…

Identifying a tumor’s molecular subtype during surgery and rapidly quantifying mutations in resected tissues intraoperatively could guide resection strategy and improve resections. Murphy, Bianchini, ...

Researchers facing

To elucidate aging-associated cellular population dynamics, we present PanSci, a single-cell transcriptome atlas profiling over 20 million cells from 623 mouse tissues across different life stages, se...

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